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Specialty: Cardiology
Condition: Cardiomyopathy

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Total 533 results found since Jan 2013.

The Impact of Segmental Volumetric Changes on Functional Mitral Regurgitation: A Study Using Three‐Dimensional Regional Time‐Volume Analysis Combined with Low‐Dose Dobutamine
ConclusionsThe FMR decreasing during low‐dose dobutamine is quantitatively associated with the regional LV volume change of attached PMs. Real time transthoracic three‐dimensional echocardiography may provide a simple and noninvasive approach to assess regional LV time‐volume characteristic during FMR.
Source: Echocardiography - September 18, 2013 Category: Cardiology Authors: Xiaofeng Chen, Ming‐Chon Hsiung, Yuming Mu Tags: Original Investigation Source Type: research

Prognostic Value of N-Terminal Pro-Brain Natriuretic Peptide in Outpatients With Hypertrophic Cardiomyopathy
In hypertrophic cardiomyopathy, the plasma levels of N-terminal pro-brain natriuretic peptide (NT-proBNP) correlate with functional capacity. However, their prognostic relevance remains unresolved. We followed up 183 stable outpatients with hypertrophic cardiomyopathy (age 50 ± 17 years, 64% men) for 3.9 ± 2.8 years after NT-proBNP measurement. The primary end point included cardiovascular death, heart transplantation, resuscitated cardiac arrest, and appropriate implantable cardioverter-defibrillator intervention. The secondary end point (SE) included heart failure-related death or hospitalization, progression to end-...
Source: The American Journal of Cardiology - July 22, 2013 Category: Cardiology Authors: Rossella D'Amato, Benedetta Tomberli, Gabriele Castelli, Roberto Spoladore, Francesca Girolami, Alessandra Fornaro, Anna Caldini, Francesca Torricelli, Paolo Camici, Gian Franco Gensini, Franco Cecchi, Iacopo Olivotto Tags: Cardiomyopathy Source Type: research

Termination of dobutamine infusion causes transient rebound left heart diastolic dysfunction in healthy elderly women but not in men: a cardiac magnetic resonance study
Men and women are known to react differently to stress. Thus, stress cardiomyopathy almost solely strikes women. Stress cardiomyopathy is suggested to relate to sex differences in catecholamine reaction. Left heart function during dobutamine stress is well described, but sex-specific inotropic and lusitropic response to abrupt termination of dobutamine stress is not. We aimed to investigate sex differences in left ventricular (LV) and atrial (LA) function during and after dobutamine stress. We enrolled 20 healthy elderly subjects (60–70 yr, 10 females) and measured their LV and LA volumes throughout the cardiac cycle...
Source: AJP: Heart and Circulatory Physiology - October 1, 2013 Category: Cardiology Authors: Ahtarovski, K. A., Iversen, K. K., Lonborg, J. T., Madsen, P. L., Engstrom, T., Vejlstrup, N. G. Tags: INTEGRATIVE CARDIOVASCULAR PHYSIOLOGY AND PATHOPHYSIOLOGY Source Type: research

Coronary artery bypass grafting in patients with left ventricular dysfunction: Predictors of long-term survival and impact of surgical strategies
This study aimed to determine predictors of clinical outcomes in patients with severe LV dysfunction undergoing CABG.Methods: Out of 6084 patients who underwent CABG between 1997 and 2011, 476 patients (aged 62.6±9.3years, 100 females) were identified as having severe LV dysfunction (ejection fraction≤35%), preoperatively. All-cause mortality and adverse cardiac events (myocardial infarction, repeat revascularization, stroke and hospitalization due to cardiovascular causes) were evaluated during a median follow-up period of 55.2months (inter-quartile range: 26.4–94.8months).Results: During the follow-up, 187 patients ...
Source: International Journal of Cardiology - August 26, 2013 Category: Cardiology Authors: Jae Suk Yoo, Joon Bum Kim, Sung-Ho Jung, Suk Jung Choo, Cheol Hyun Chung, Jae Won Lee Tags: Original Articles Source Type: research

Peak systolic velocity of pulmonary venous flow and mitral annulus are independent predictors of left ventricular global longitudinal strain in patients with cardiomyopathy
Measurement of pulmonary venous flow (PVF) by Doppler echocardiography is a useful tool for evaluating left ventricular (LV) diastolic dysfunction. It is most often used in combination with transmitral flow and tissue Doppler imaging of mitral annular motion in patients with heart failure . Peak systolic velocity (S-vel) of PVF is affected by LV contractility, stroke volume, and decrease in the systolic descent of the mitral annulus . The recently developed two-dimensional (2D) strain imaging, based on speckle tracking echocardiography, is an objective imaging method that allows tracking of longitudinal and circumferential...
Source: International Journal of Cardiology - August 26, 2013 Category: Cardiology Authors: Jun Koyama, Ayako Kozuka, Masatoshi Minamisawa, Hirohiko Motoki, Atsushi Izawa, Takeshi Tomita, Yusuke Miyashita, Masafumi Takahashi, Uichi Ikeda Tags: Letters to the Editor Source Type: research

Adverse Cardiovascular, Cerebrovascular, and Peripheral Vascular Effects of Marijuana Inhalation: What Cardiologists Need to Know
In conclusion, the potential for increased use of marijuana in the changing legal landscape suggests the need for the community to intensify research regarding the safety of marijuana use and for cardiologists to maintain an awareness of the potential for adverse effects.
Source: The American Journal of Cardiology - October 30, 2013 Category: Cardiology Authors: Grace Thomas, Robert A. Kloner, Shereif Rezkalla Tags: Review Source Type: research

Progress: the ROPAC multinational registry advances our understanding of an important outcome in pregnant women with heart disease
When caring for women with structural heart disease (SHD), clinicians face an apparent paradox: most women with SHD are able to complete a pregnancy without complication; however, compared with the general population, maternal risk is increased and SHD remains a major source of maternal morbidity and mortality and poor fetal outcomes.1–4 Identifying those women with SHD who are at increased risk for meaningful complications during pregnancy is critical. During pregnancy, intravascular volume, stroke volume, heart rate and cardiac output increase, while systemic vascular resistance decreases. During pregnancy, women w...
Source: Heart - January 3, 2014 Category: Cardiology Authors: Krieger, E. V., Stout, K. K. Tags: Congenital heart disease, Drugs: cardiovascular system, Hypertension, Acute coronary syndromes, Epidemiology Editorials Source Type: research

Predictors of Long-Term Outcomes in Patients with Significant Myxomatous Mitral Regurgitation Undergoing Exercise Echocardiography.
CONCLUSIONS: In patients with ≥III+ myxomatous MR undergoing ExEc, lower %age-gender predicted METS, lower HRR, atrial fibrillation, lower LV ejection fraction and high resting RVSP predicted worse outcomes. PMID: 24396041 [PubMed - as supplied by publisher]
Source: Circulation - January 6, 2014 Category: Cardiology Authors: Naji P, Griffin BP, Asfahan F, Barr TS, Rodriguez LL, Grimm R, Agarwal S, Stewart WJ, Mihaljevic T, Gillinov AM, Desai MY Tags: Circulation Source Type: research

Echocardiographic Evaluation of the Effects of Stem Cell Therapy on Perfusion and Function in Ischemic Cardiomyopathy
Background: Small animal models of ischemic left ventricular (LV) dysfunction are important for the preclinical optimization of stem cell therapy. The aim of this study was to test the hypothesis that temporal changes in LV function and regional perfusion after cell therapy can be assessed in mice using echocardiographic imaging.Methods: Wild-type mice (n = 25) were studied 7 and 28 days after permanent ligation of the left anterior descending coronary artery. Animals were randomized to receive closed-chest ultrasound-guided intramyocardial delivery of saline (n = 13) or 5 × 105 multipotential adult progenitor cell...
Source: Journal of the American Society of Echocardiography - December 5, 2013 Category: Cardiology Authors: Yoichi Inaba, Brian P. Davidson, Sajeevani Kim, Ya Ni Liu, William Packwood, J. Todd Belcik, Aris Xie, Jonathan R. Lindner Tags: Coronary Perfusion and Function Source Type: research

Systolic and Diastolic Mechanics in Stress Cardiomyopathy.
CONCLUSIONS: SCM and LAD MI show severe diastolic dysfunction: at similar LV volumes, their diastolic pressures are more than twice as high as control; systolic dysfunction is equally reduced in SCM and LAD MI. Despite a completely different pathophysiology, as far as systolic and diastolic function, SCM is indistinguishable from acute LAD territory MI. PMID: 24503950 [PubMed - as supplied by publisher]
Source: Circulation - February 6, 2014 Category: Cardiology Authors: Medeiros K, O'Connor M, Aurigemma GP, Baicu CF, Fitzgibbons T, Zile MR, Tighe DA, Shaw P Tags: Circulation Source Type: research

Preventing Cardiovascular Complications of Acute Infection: A Missed Opportunity?
Abstract "...This is an experimental verification of this medical concept, relatively new, suggesting that infections merit an important place in the etiology of human atheromatous arteritis..." -Gilbert A and Lion G, Comptes Rendus Hebdomadairesdes Séances et Mémoires de la Société de Biologie. Published 1889 The connections between infection and cardiovascular disease have been postulated for at least 125 years, when Gilbert and Lion observed that acute infection with the typhoid bacillus resulted in atherosclerotic changes to the rabbit aorta. In the last few decades, much work has investigated the role for...
Source: Circulation - February 12, 2014 Category: Cardiology Authors: Walkey AJ Tags: Circulation Source Type: research

Takotsubo cardiomyopathy: A review.
Abstract Abstract Takotsubo cardiomyopathy can occur after acute mental or physical stress, subarachnoid hemorrhage, ischemic stroke, major head trauma, acute medical illness or acute pheochromocytoma crisis. It is characterized by transient systolic dysfunction of the apical and/or midventricular segments in patients without epicardial coronary artery disease. The condition occurs most commonly in postmenopausal women, and is characterized by transient left ventricular dysfunction. The pathophysiology of the disorder remains to be elucidated but may involve catecholamine excess and vasospasm. Future studies, perh...
Source: Acute Cardiac Care - February 22, 2014 Category: Cardiology Authors: Veillet-Chowdhury M, Hassan SF, Stergiopoulos K Tags: Acute Card Care Source Type: research

Cardiac MRI assessment of atrial fibrosis in atrial fibrillation: implications for diagnosis and therapy
Atrial fibrillation (AF) is the most commonly encountered cardiac arrhythmia in clinical practice, with a prevalence of 0.4–1% in the US population.w1 AF is a potent risk factor, increasing the risk of stroke fivefold and accounting for approximately 15% of all strokes in the USA.w2 AF also significantly increases the risk of mortality from heart failure.w3–7 Many therapies, including pharmacological approaches and direct current cardioversion, have been tried to treat this malignant arrhythmia, but were not found to be that effective.1 w8–w11 Catheter ablation of AF has provided better outcomes compared ...
Source: Heart - March 5, 2014 Category: Cardiology Authors: Higuchi, K., Akkaya, M., Akoum, N., Marrouche, N. F. Tags: Tachyarrhythmias, Atrial fibrillation, Education in Heart, Dilated cardiomyopathy, Hypertrophic cardiomyopathy, Drugs: cardiovascular system, Echocardiography, Heart failure, Acute coronary syndromes, Clinical diagnostic tests, Epidemiology Source Type: research

Natriuretic Peptide: A Probable Culprit in Prevention of Primary Cardiovascular Diseases Using {beta}-Blockers Letters to the Editor
Source: Hypertension - March 12, 2014 Category: Cardiology Authors: Peng, H., Liu, Y. Tags: Biochemistry and metabolism, Cerebrovascular disease/stroke, Myocardial cardiomyopathy disease Letters to the Editor Source Type: research

Three‐Dimensional Speckle Tracking Echocardiography Allows Detailed Evaluation of Left Atrial Function in Hypertrophic Cardiomyopathy–Insights from the MAGYAR‐Path Study
ConclusionsThree‐dimensional speckle tracking echocardiography allows detailed evaluation of LA (dys) function in HCM by volumetric and strain measurements.
Source: Echocardiography - March 20, 2014 Category: Cardiology Authors: Péter Domsik, Anita Kalapos, Számi Chadaide, Róbert Sepp, Péter Hausinger, Tamás Forster, Attila Nemes Tags: Original Investigation Source Type: research