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Specialty: Biochemistry

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Total 1283 results found since Jan 2013.

Some miRNA expressions and their targets in ischemic stroke
Nucleosides Nucleotides Nucleic Acids. 2022 Jul 23:1-39. doi: 10.1080/15257770.2022.2098974. Online ahead of print.ABSTRACTIschemic stroke (IS) is a global health challenge leading to life-long disabilities or the deaths of patients. IS is a complex disease where genetic and environmental factors are both concerned with the pathophysiology of the condition. Here, we aimed to investigate various microRNA (miRNA) expressions and their targets in IS. A rapid and accurate diagnosis of acute IS is important to perform appropriate treatment. Therefore, there is a need for a more rapid and simple tool to carry out an acute diagno...
Source: Nucleosides, Nucleotides and Nucleic Acids - July 25, 2022 Category: Biochemistry Authors: Ummugulsum Can Ebru Marzioglu Sadinaz Akdu Source Type: research

Biomechanical regulation of planar cell polarity in endothelial cells
This study provides new ideas and therapeutic targets for the treatment of endothelial PCP-related diseases.PMID:35850177 | DOI:10.1016/j.bbadis.2022.166495
Source: Biochimica et Biophysica Acta - July 19, 2022 Category: Biochemistry Authors: Caihong Wang Kai Qu Jing Wang Rui Qin Bingyi Li Juhui Qiu Guixue Wang Source Type: research

Association between obstructive sleep apnea and cardiovascular diseases
Acta Biochim Biophys Sin (Shanghai). 2022 Jul 25. doi: 10.3724/abbs.2022084. Online ahead of print.ABSTRACTObstructive sleep apnea (OSA) is a common respiratory disorder characterized by partial obstruction of upper respiratory tract and repetitive cessation of breathing during sleep. The etiology behind OSA is associated with the occurrence of intermittent hypoxemia, recurrent arousals and intrathoracic pressure swings. These contributing factors may turn on various signaling mechanisms including elevated sympathetic tone, oxidative stress, inflammation, endothelial dysfunction, cardiovascular variability, abnormal coagul...
Source: Acta Biochimica et Biophysica Sinica - July 15, 2022 Category: Biochemistry Authors: Yiran E Li Jun Ren Source Type: research

Cynaropicrin Averts the Oxidative Stress and Neuroinflammation in Ischemic/Reperfusion Injury Through the Modulation of NF-kB
Appl Biochem Biotechnol. 2022 Jul 15. doi: 10.1007/s12010-022-04060-x. Online ahead of print.ABSTRACTCerebral ischemia and successive reperfusion are the prevailing cause of cerebral stroke. Currently cerebral stroke is considered to be one of the prior causes for high mortality, disability, and morbidity. Cynaropicrin, a sesquiterpene lactone, exhibits various pharmacologic properties and also has an anti-inflammatory property associated with the suppression of the key pro-inflammatory NF-κB pathway. The protective effect of cynaropicrin against oxidative stress and neuroinflammation during CIR injury through the modulat...
Source: Applied Biochemistry and Biotechnology - July 15, 2022 Category: Biochemistry Authors: Tao Jin Bing Leng Source Type: research

Association between obstructive sleep apnea and cardiovascular diseases
Acta Biochim Biophys Sin (Shanghai). 2022 Jul 25. doi: 10.3724/abbs.2022084. Online ahead of print.ABSTRACTObstructive sleep apnea (OSA) is a common respiratory disorder characterized by partial obstruction of upper respiratory tract and repetitive cessation of breathing during sleep. The etiology behind OSA is associated with the occurrence of intermittent hypoxemia, recurrent arousals and intrathoracic pressure swings. These contributing factors may turn on various signaling mechanisms including elevated sympathetic tone, oxidative stress, inflammation, endothelial dysfunction, cardiovascular variability, abnormal coagul...
Source: Acta Biochimica et Biophysica Sinica - July 15, 2022 Category: Biochemistry Authors: Yiran E Li Jun Ren Source Type: research

Cynaropicrin Averts the Oxidative Stress and Neuroinflammation in Ischemic/Reperfusion Injury Through the Modulation of NF-kB
Appl Biochem Biotechnol. 2022 Jul 15. doi: 10.1007/s12010-022-04060-x. Online ahead of print.ABSTRACTCerebral ischemia and successive reperfusion are the prevailing cause of cerebral stroke. Currently cerebral stroke is considered to be one of the prior causes for high mortality, disability, and morbidity. Cynaropicrin, a sesquiterpene lactone, exhibits various pharmacologic properties and also has an anti-inflammatory property associated with the suppression of the key pro-inflammatory NF-κB pathway. The protective effect of cynaropicrin against oxidative stress and neuroinflammation during CIR injury through the modulat...
Source: Applied Biochemistry and Biotechnology - July 15, 2022 Category: Biochemistry Authors: Tao Jin Bing Leng Source Type: research