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Specialty: Biochemistry
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Total 1283 results found since Jan 2013.
Identification of ligustrazine-based analogs of piperlongumine as potential anti-ischemic stroke agents
Fitoterapia. 2022 Dec 20:105398. doi: 10.1016/j.fitote.2022.105398. Online ahead of print.ABSTRACTPiper longum has a specific aroma and spicy taste. In addition to edible value, current studies have shown that piper longum also has pharmacological activities such as anti-platelet aggregation, anti-inflammation, anti-cancer, anti-diabetes and anti-depression. Piperlongumine is an alkaloid isolated from Piper longum. Based on our previous studies, four Piperlongumine analogs were synthesized, and their anti-platelet aggregation activities were evaluated. Among them, compound 8 has the strongest anti-platelet aggregation acti...
Source: Fitoterapia - December 23, 2022 Category: Biochemistry Authors: Tan Lijuan Cao Xiaolu Wan Xin He Yuying Lan Xi Yang Xiliang Wang Ting Min Zhenli Zou Yu Source Type: research
ASAP Nuclear Magnetic Resonance-Based Metabolomics to Predict Early and Late Adverse Outcomes in Ischemic Stroke Treated with Intravenous Thrombolysis
Journal of Proteome ResearchDOI: 10.1021/acs.jproteome.2c00333
Source: Journal of Proteome Research - December 5, 2022 Category: Biochemistry Authors: Cristina Licari, Leonardo Tenori, Francesca Di Cesare, Claudio Luchinat, Betti Giusti, Ada Kura, Rosina De Cario, Domenico Inzitari, Benedetta Piccardi, Mascia Nesi, Cristina Sarti, Francesco Arba ⧫, Vanessa Palumbo, Patrizia Nencini, Rossella Marcucci, Source Type: research
Neurofilaments: a key new biomarker for clinicians. Part 2: Neurofilaments, an asset beyond neurodegenerative diseases
This article completes the first part, in which we presented the interest of NfL in the context of neurodegenerative diseases. Here we focus our review on other clinical contexts of neurological injury (such as traumatic brain injury, multiple sclerosis, stroke, and cancer) and present the potential value of NfL assay in the management of these patients, for both diagnosis and prognosis. We also discuss the added value of the NfL assay compared to other biomarkers commonly used in the described clinical situations.PMID:36453743 | DOI:10.1684/abc.2022.1758
Source: Annales de Biologie Clinique - December 1, 2022 Category: Biochemistry Authors: Constance Delaby Olivier Bousiges Damien Bouvier Catherine Fill ée Anthony Fourier Étienne Mondésert Nicolas Nezry Souheil Omar Isabelle Quadrio Benoit Rucheton Susanna Schraen-Maschke Vincent van Pesch St éphanie Vicca Sylvain Lehmann Aur élie Bedel Source Type: research
