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Total 3346 results found since Jan 2013.

Effects of IL-6 and cortisol fluctuations in post-stroke depression
This study will help the screening of potential PSD in the early stage.
Source: Journal of Huazhong University of Science and Technology -- Medical Sciences -- - September 30, 2016 Category: Research Source Type: research

Diaphragm Thickness and Inspiratory Muscle Functions in Chronic Stroke Patients.
CONCLUSIONS Stroke patients showed decreases in the thickening ability of the diaphragm at TLC and in inspiratory muscle function. The change between the diaphragm thickness at end expiration and at TLC was positively correlated with MIP, PIF, and VC. PMID: 28284044 [PubMed - in process]
Source: Medical Science Monitor - March 12, 2017 Category: Research Tags: Med Sci Monit Source Type: research

Risk of stroke/systemic embolism, major bleeding and associated costs in non-valvular atrial fibrillation patients who initiated apixaban, dabigatran, or rivaroxaban compared with warfarin in the United States Medicare population.
CONCLUSIONS: Among the DOACs in the study, only apixaban is associated with a significantly lower risk of stroke/SE and major bleeding and lower related medical costs compared to warfarin. PMID: 28635338 [PubMed - as supplied by publisher]
Source: Current Medical Research and Opinion - June 22, 2017 Category: Research Tags: Curr Med Res Opin Source Type: research

Adequate Platelet Function Inhibition Confirmed by Two Inductive Agents Predicts Lower Recurrence of Ischemic Stroke/Transient Ischemic Attack.
CONCLUSION: The platelet function tested by PL-11 demonstrated that adequate inhibition of both MARADP and MARAA could predict lower risk of ischemic stroke/TIA recurrence. PMID: 28913351 [PubMed - in process]
Source: Biomed Res - September 16, 2017 Category: Research Authors: Zhang L, Hu X, Zhu J, Cai X, Kong Y, Wang H, Diao S, Zhao H, Jiang J, Wang D, Zhang Q, Qin Y, Yue W, Fang Q Tags: Biomed Res Int Source Type: research

Factors associated with stroke, myocardial infarction, ischemic heart disease, unstable angina, or mortality in patients from real world clinical practice with newly diagnosed type 2 diabetes and early glycemic control.
CONCLUSIONS: Early and sustained HbA1c control between 6.5 and <7.0% is an important modifiable factor that helps reduce CV risk in patients with newly-diagnosed T2DM in real-world clinical practice. PMID: 29065729 [PubMed - as supplied by publisher]
Source: Current Medical Research and Opinion - October 29, 2017 Category: Research Tags: Curr Med Res Opin Source Type: research

A retrospective study to assess resource utilization and costs in patients with post-stroke spasticity in the United Kingdom.
CONCLUSION: Costs after stroke for patients developing PSS are twice as high compared to patients who do not develop it, with the major driver being the number of hospital admissions. This highlights the need for better recording and closer management of PSS. PMID: 29490512 [PubMed - as supplied by publisher]
Source: Current Medical Research and Opinion - March 3, 2018 Category: Research Tags: Curr Med Res Opin Source Type: research

Patent foramen ovale closure or medical therapy for cryptogenic ischemic stroke: an updated meta-analysis of randomized controlled trials.
CONCLUSIONS: PFO-C after cryptogenic ischemic stroke is safe and effective to reduce the risk of recurrent stroke and recurrent stroke + TIA, albeit with an increased risk for NOAF. PMID: 29500568 [PubMed - as supplied by publisher]
Source: Clin Med Res - March 2, 2018 Category: Research Authors: Schulze V, Lin Y, Karathanos A, Brockmeyer M, Zeus T, Polzin A, Perings S, Kelm M, Wolff G Tags: Clin Res Cardiol Source Type: research

Improvement of Endovascular Stroke Treatment: A 24-Hour Neuroradiological On-Site Service Is Not Enough.
Conclusions: A 24-hour interventional on-site service is a major prerequisite to adequately provide modern reperfusion therapies in patients with acute ischemic stroke. However, simple measures like standardized and focused documentation that affect the entire interdisciplinary pre- and intrahospital stroke rescue chain seem to be important. PMID: 29516015 [PubMed - in process]
Source: Biomed Res - March 10, 2018 Category: Research Authors: Nikoubashman O, Schürmann K, Othman AE, Bach JP, Wiesmann M, Reich A Tags: Biomed Res Int Source Type: research

Decreased Respiratory Muscle Function Is Associated with Impaired Trunk Balance among Chronic Stroke Patients: A Cross-sectional Study.
Abstract The abdominal muscles play a role in trunk balance. Abdominal muscle thickness is asymmetrical in stroke survivors, who also have decreased respiratory muscle function. We compared the thickness of the abdominal muscles between the affected and less affected sides in stroke survivors. In addition, the relationship between respiratory muscle function and trunk balance was evaluated. Chronic stroke patients (18 men, 15 women; mean age, 58.94 ± 12.30 years; Mini-Mental Status Examination score ≥ 24) who could sit without assist were enrolled. Abdominal muscle thickness during rest and contraction was meas...
Source: The Tohoku Journal of Experimental Medicine - June 2, 2018 Category: Research Authors: Lee K, Cho JE, Hwang DY, Lee W Tags: Tohoku J Exp Med Source Type: research

Mean Platelet Volume, C-Reactive Protein, and Prognosis in Patients with Acute Ischemic Stroke Following Intravenous Thrombolytic Treatment.
CONCLUSIONS MPV and CRP values were significantly associated with improvement in the NIH Stroke Scale and MRS scores in AIS when patients were treated with IV thrombolytic therapy within 4.5 hours of the onset of symptoms. PMID: 29869620 [PubMed - in process]
Source: Medical Science Monitor - June 7, 2018 Category: Research Tags: Med Sci Monit Source Type: research

Prevalence of Abnormal Glucose Regulation according to Different Diagnostic Criteria in Ischaemic Stroke without a History of Diabetes.
Abstract We aimed to investigate the prevalence and distribution of abnormal glucose regulation, including prediabetes and newly diagnosed diabetes, according to different criteria in ischaemic stroke patients without a history of diabetes. Data were derived from a representative cohort across China. Prediabetes was defined as fasting plasma glucose (FPG) 5.6-6.9 mmol/L or 2-hour oral glucose tolerance test (OGTT) 7.8-11.0 mmol/L or haemoglobin A1c (HbA1c) 5.7-6.4%. Newly diagnosed diabetes was defined as FPG ≥ 7.0 mmol/L, 2 h OGTT ≥ 11.1 mmol/L or HbA1c ≥ 6.5%. Among 1251 ischaemic stroke patients...
Source: Biomed Res - June 30, 2018 Category: Research Authors: Zhang X, Shi Q, Zheng H, Jia Q, Zhao X, Liu L, Wang C, Meng X, Jing J, Pan Y, Wang Y, Wang Y Tags: Biomed Res Int Source Type: research

Comparison of Quantitative and Qualitative Oxygen Extraction Fraction (OEF) in Acute Stroke Patients with Large Vessel Occlusion.
Authors: Nemoto E, Lin R, Uchino K, Billigen J, Bircher N, Zaidi S, Reddy V, Jumma M, Kuwabara H, Sashin D, Boada F, Chang YF, Vora N, Hammer M, Jovin T, Massaro L, Zhang T, Matsumoto K, Yonas H Abstract The superficial temporal artery-middle cerebral artery bypass (STA-MCA) bypass surgery developed by Donaghy and Yarsagil in 1967 provided relief for patients with acute stroke and large vessel occlusive vascular disease. Early reports showed low morbidity and good outcomes. However, a large clinical trial in 1985 reported a failure of extracranial-intracranial (EC/IC) bypass to show benefit in reducing the risk of ...
Source: Advances in Experimental Medicine and Biology - September 6, 2018 Category: Research Tags: Adv Exp Med Biol Source Type: research

Modeling the impact of real-world adherence to once-daily (QD) versus twice-daily (BID) non-vitamin K antagonist oral anticoagulants on stroke and major bleeding events among non-valvular atrial fibrillation patients.
CONCLUSION: QD NOACs prevented a significant number of strokes and caused no significant increase in MBs compared to BID NOACs which leads to significant net cost savings for NVAF patients in the US. PMID: 30265159 [PubMed - as supplied by publisher]
Source: Current Medical Research and Opinion - September 29, 2018 Category: Research Tags: Curr Med Res Opin Source Type: research

Exosomes from miRNA-126-modified ADSCs promotes functional recovery after stroke in rats by improving neurogenesis and suppressing microglia activation.
Authors: Geng W, Tang H, Luo S, Lv Y, Liang D, Kang X, Hong W Abstract Although adipose derived stem cells (ADSCs) exert their therapeutic potential in ischemic stroke, the migration of ADSCs in injured area is not apparently observed after intravenous administration. ADSCs are an important source of exosomes which hold great promise as an endogenous drug delivery system for the treatment of cerebral ischemia given their ability to cross the blood-brain barrier. Here we investigated whether ADSCs-derived exosomes mediated miRNAs transfer and thus promoted neurological recovery after stroke. We first proved that miR...
Source: American Journal of Translational Research - March 24, 2019 Category: Research Tags: Am J Transl Res Source Type: research

Impact of serum omentin-1 levels on functional prognosis in nondiabetic patients with ischemic stroke.
CONCLUSION: In this cohort of nondiabetic patients with ischemic stroke, a reduced baseline level of serum omentin-1 was related with an increased risk for poor functional outcome or death, independent of baseline variables. PMID: 30972209 [PubMed]
Source: American Journal of Translational Research - April 13, 2019 Category: Research Tags: Am J Transl Res Source Type: research