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Condition: Hemorrhagic Stroke
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Total 196 results found since Jan 2013.

Machine learning prediction of symptomatic intracerebral hemorrhage after stroke thrombolysis: a cross-cultural validation in Caucasian and Han Chinese cohort
CONCLUSION: The established SVM model is feasible for predicting the risk of sICH after thrombolysis quickly and efficiently in both Caucasian and Han Chinese cohort.PMID:36225969 | PMC:PMC9549180 | DOI:10.1177/17562864221129380
Source: Adv Data - October 13, 2022 Category: Epidemiology Authors: Junfeng Liu Xinyue Chen Xiaonan Guo Renjie Xu Yanan Wang Ming Liu Source Type: research

Machine learning and acute stroke imaging
Conclusions ML in acute ischemic stroke imaging has already made tremendous headway. Additional applications and further integration with clinical care is inevitable. Thus, facility with these approaches is critical for the neurointerventional clinician.
Source: Journal of NeuroInterventional Surgery - January 11, 2023 Category: Neurosurgery Authors: Sheth, S. A., Giancardo, L., Colasurdo, M., Srinivasan, V. M., Niktabe, A., Kan, P. Tags: Neuroimaging Source Type: research

Ctbrain machine learning predicts stroke thrombolysis result
Conclusions This proof-of-concept study shows that machine learning methods applied to acute stroke CT-scans potentially offers automation, and improved performance in SICH prediction following thrombolysis. Larger-scale cohorts, and incorporation of CT perfusion/angiography data, should be tested with such methods.
Source: Journal of Neurology, Neurosurgery and Psychiatry - September 9, 2014 Category: Neurosurgery Authors: Epton, S., Bentley, P., Ganesalingam, J., Dias, A., Mahady, K., Rinne, P., Sharma, P., Halse, O., Mehta, A., Rueckert, D. Tags: Abstracts Source Type: research

Microwave-Based Stroke Diagnosis Making Global Prehospital Thrombolytic Treatment Possible
Here, we present two different brain diagnostic devices based on microwave technology and the associated two first proof-of-principle measurements that show that the systems can differentiate hemorrhagic from ischemic stroke in acute stroke patients, as well as differentiate hemorrhagic patients from healthy volunteers. The system was based on microwave scattering measurements with an antenna system worn on the head. Measurement data were analyzed with a machine-learning algorithm that is based on training using data from patients with a known condition. Computer tomography images were used as reference. The detection meth...
Source: IEEE Transactions on Biomedical Engineering - October 17, 2014 Category: Biomedical Engineering Source Type: research

Effects of thalamic hemorrhagic lesions on explicit and implicit learning during the acquisition and retrieval phases in an animal model of central post-stroke pain.
Abstract Hemorrhagic stroke has many symptoms, including central pain, learning and memory impairments, motor deficits, language problems, emotional disturbances, and social maladjustment. Lesions of the ventral basal complex (VBC) of the thalamus elicit thermal and mechanical hyperalgesia, forming an animal model of central post-stroke pain (CPSP). However, no research has yet examined the involvement of learning and memory in CPSP using an animal model. The present study examined whether VBC lesions affect motor function, conditioned place preference (CPP; implicit memory), and spatial learning (explicit memory)...
Source: Behavioural Brain Research - September 24, 2016 Category: Neurology Authors: Wang CC, Shih HC, Shyu BC, Huang AC Tags: Behav Brain Res Source Type: research

Study Documents Neurological, Psychiatric Complications From COVID-19
While previous studies and case reports have found that COVID-19 patients have experienced vascular and neurological problems, a newstudy inthe Lancet Psychiatry reports that patients are also showing symptoms of psychiatric disorders, including psychosis and depression.The study was the result of a collaborative effort of specialists in the United Kingdom to document COVID-19 complications.“To our knowledge, this is the first systematic, nationwide U.K. surveillance study of the breadth of acute complications of COVID-19 in the nervous system,” wrote Aravinthan Varatharaj, M.R.C.P., of University Hospital Southampton ...
Source: Psychiatr News - June 29, 2020 Category: Psychiatry Tags: Aravinthan Varatharaj brain hemorrhage brain inflammation cognition COVID-19 depression Lancet Psychiatry pain psychiatric disorders psychosis stroke United Kingdom weakness Source Type: research

Machine Learning-Based Model for Prediction of Hemorrhage Transformation in Acute Ischemic Stroke After Alteplase
In this study, an RF machine learning method was successfully established to predict HT in AIS patients after intravenous alteplase, which the sensitivity was 66.7%, and the specificity was 80.7%.
Source: Frontiers in Neurology - June 10, 2022 Category: Neurology Source Type: research

Concurrent validity of machine learning-classified functional upper extremity use from accelerometry in chronic stroke
Conclusion: Our machine learning approach provides a valid measure of functional UE use. The accuracy, validity, and small footprint of this machine learning approach makes it feasible for measurement of UE recovery in stroke rehabilitation trials.
Source: Frontiers in Physiology - March 22, 2023 Category: Physiology Source Type: research

Posterior Fossa Syndrome After Cerebellar Stroke.
We report longitudinal clinical, neurocognitive and neuroradiological findings in a 71-year-old right-handed patient who developed PFS following a right cerebellar haemorrhage that was not surgically evacuated. During follow-up, functional neuroimaging was conducted by means of quantified Tc-99m-ECD SPECT studies. After a 10-day period of akinetic mutism, the clinical picture developed into cerebellar cognitive affective syndrome (CCAS) with reversion to a previously learnt accent, consistent with neurogenic foreign accent syndrome (FAS). No psychometric evidence for dementia was found. Quantified Tc-99m-ECD SPECT studies ...
Source: Cerebellum - April 11, 2013 Category: Neuroscience Authors: Mariën P, Verslegers L, Moens M, Dua G, Herregods P, Verhoeven J Tags: Cerebellum Source Type: research

Keeping up with Amanda: Life after brain surgery
In most ways, Amanda LePage is just like any other rambunctious fourth grader. She loves school, dance class, playing basketball and keeping up with her twin sister Macy and older brother Nathan. Sometimes it just takes her a little longer to do these everyday things. That’s because Amanda has been through a lot in her short nine years. Amanda was just 5 months old when she was brought by helicopter to Boston Children’s Hospital for a hemorrhage in her brain from an intracranial aneurysm, a type of vascular malformation. Despite long odds, Amanda survived two life-saving brain surgeries and a massive stroke that left ...
Source: Thrive, Children's Hospital Boston - May 22, 2017 Category: Pediatrics Authors: Ellen Greenlaw Tags: Our Patients’ Stories brain aneurysm Dr. Caroline Robson Dr. Craig McClain Dr. Edward Smith Dr. Peter Manley Hydrocephalus low-grade glioma pediatric stroke Source Type: news

Prediction of Hemorrhagic Transformation Severity in Acute Stroke From Source Perfusion MRI
Conclusion: The key contribution of our framework formalize HT prediction as a machine learning problem. Specifically, the model learns to extract imaging markers of HT directly from source PWI images rather than from pre-established metrics. Significance: Predictions visualized in terms of spatial likelihood of HT in various territories of the brain were evaluated against follow-up gradient recalled echo and provide novel insights for neurointerventionalists prior to endovascular therapy.
Source: IEEE Transactions on Biomedical Engineering - August 21, 2018 Category: Biomedical Engineering Source Type: research

Beneficial actions of prothymosin alpha-mimetic hexapeptide on central post-stroke pain, reduced social activity, learning-deficit and depression following cerebral ischemia in mice
Publication date: Available online 23 January 2020Source: PeptidesAuthor(s): Keita Sasaki, Sebok Kumar Halder, Hayato Matsunaga, Hiroshi UedaAbstractProthymosin alpha (ProTα)-mimetic hexapeptide (amino acid: NEVDQE, P6Q) inhibits cerebral or retinal ischemia-induced behavioral, electrophysiological and histological damage. P6Q also abolishes cerebral hemorrhage induced by ischemia with tissue plasminogen activator (tPA). In the present study we examined the beneficial effects of P6Q on other post-stroke prognostic psychology-related symptoms, which obstruct the motivation toward physical therapy. Intravenous (i.v.) admini...
Source: Peptides - January 24, 2020 Category: Biochemistry Source Type: research

Natural Language Processing of Radiology Reports to Detect Complications of Ischemic Stroke
ConclusionsOur study demonstrates robust performance and external validity of a core NLP tool kit for identifying both categorical and continuous outcomes of ischemic stroke from unstructured radiographic text data. Medically tailored NLP methods have multiple important big data applications, including scalable electronic phenotyping, augmentation of clinical risk prediction models, and facilitation of automatic alert systems in the hospital setting.
Source: Neurocritical Care - May 9, 2022 Category: Neurology Source Type: research

Diagnostic model constructed by nine inflammation-related genes for diagnosing ischemic stroke and reflecting the condition of immune-related cells
ConclusionsTaken together, the diagnostic model constructed using the inflammation-related genes TNFSF10, ID1, PAQR8, OSR2, PDK4, PEX11B, TNIP1, FFAR2, and JUN exhibited high and specific diagnostic value for IS and reflected the condition of lymphocytes, monocytes, and neutrophils in the blood. The diagnostic model may contribute to the diagnosis of IS.
Source: Frontiers in Immunology - December 13, 2022 Category: Allergy & Immunology Source Type: research