Proactive Air Management in CT Power Injections: A Comprehensive Approach to Reducing Air Embolization
This study reviews the challenges associated with reactive air management approaches employed on contemporary systems, proposes a novel air management approach using proactive methods, and compares the impact of reactive and proactive approaches on injected air volumes under simulated clinical use. Methods: Injected air volumes from three power injection systems were measured under simulated clinical use via custom air trap fixture. Two of the systems employed reactive air management approaches, while a new system implemented the proposed proactive air management approach. Results: The proactive system injected significant...
Source: IEEE Transactions on Biomedical Engineering - February 19, 2021 Category: Biomedical Engineering Source Type: research

Prediction of Individual Knee Kinematics From an MRI Representation of the Articular Surfaces
Conclusion: The proposed approach allows the prediction of individual joint motion based on non-ionizing MRI data. Significance: This method may help to characterize healthy and, by comparison, pathological knee behavior. Moreover, it may provide an individual reference motion for the personalization of musculoskeletal models, opening the way to their clinical application. (Source: IEEE Transactions on Biomedical Engineering)
Source: IEEE Transactions on Biomedical Engineering - February 19, 2021 Category: Biomedical Engineering Source Type: research

Principal Component Analysis in Projection and Image Domains—Another Form of Spectral Imaging in Photon-Counting CT
Conclusion: The PCA in either projection or image domain provides another form of spectral imaging in photon-counting CT that fits the essential requirements on spectral imaging in true color. Significance: The verification of PCA's feasibility in CT as a form spectral imaging and observation of its potential superiority in CNR over conventional polychromatic CT are meaningful in theory and practice. (Source: IEEE Transactions on Biomedical Engineering)
Source: IEEE Transactions on Biomedical Engineering - February 19, 2021 Category: Biomedical Engineering Source Type: research

Fiber Optic Sensors-Based Thermal Analysis of Perfusion-Mediated Tissue Cooling in Liver Undergoing Laser Ablation
The current challenge in the field of thermo-ablative treatments of tumors is to achieve a balance between complete destruction of malignant cells and safeguarding of the surrounding healthy tissue. Blood perfusion plays a key role for thermal ablation success, especially in the case of highly vascularized organs like liver. This work aims at monitoring the temperature within perfused swine liver undergoing laser ablation (LA). Temperature was measured through seven arrays of Fiber Bragg Grating sensors (FBGs) around the laser applicator. To mimic reality, blood perfusion within the ex-vivo liver was simulated using artifi...
Source: IEEE Transactions on Biomedical Engineering - February 19, 2021 Category: Biomedical Engineering Source Type: research

Electrocardiogram Derived Respiratory Rate Using a Wearable Armband
A method for deriving respiratory rate from an armband, which records three-channel electrocardiogram (ECG) using three pairs of dry (no hydrogel) electrodes, is presented. The armband device is especially convenient for long-term (months-years) monitoring because it does not use obstructive leads nor hydrogels/adhesives, which cause skin irritation even after few days. An ECG-derived respiration (EDR) based on respiration-related modulation of QRS slopes and R-wave angle approach was used. Moreover, we modified the EDR algorithm to lower the computational cost. Respiratory rates were estimated with the armband-ECG and the...
Source: IEEE Transactions on Biomedical Engineering - February 19, 2021 Category: Biomedical Engineering Source Type: research

Evaluation of Non-Invasive Ankle Joint Effort Prediction Methods for Use in Neurorehabilitation Using Electromyography and Ultrasound Imaging
Conclusion: The findings indicate FFNN or HNM approach and using pennation angle or fascicle length predict human ankle movement intent with higher accuracy. Significance: The accurate ankle effort prediction will pave the path to safe and reliable robotic assistance in patients with drop foot. (Source: IEEE Transactions on Biomedical Engineering)
Source: IEEE Transactions on Biomedical Engineering - February 19, 2021 Category: Biomedical Engineering Source Type: research

Efficient Medical Instrument Detection in 3D Volumetric Ultrasound Data
Ultrasound-guided procedures have been applied in many clinical therapies, such as cardiac catheterization and regional anesthesia. Medical instrument detection in 3D Ultrasound (US) is highly desired, but the existing approaches are far from real-time performance. Our objective is to investigate an efficient instrument detection method in 3D US for practical clinical use. We propose a novel Multi-dimensional Mixed Network for efficient instrument detection in 3D US, which extracts the discriminating features at 3D full-image level by a 3D encoder, and then applies a specially designed dimension reduction block to reduce t...
Source: IEEE Transactions on Biomedical Engineering - February 19, 2021 Category: Biomedical Engineering Source Type: research

Image Guidance in Deep Brain Stimulation Surgery to Treat Parkinson's Disease: A Comprehensive Review
This article surveys the state-of-the-art techniques in image-guided DBS surgery to treat PD, and discusses their benefits and drawbacks, as well as future directions on the topic. (Source: IEEE Transactions on Biomedical Engineering)
Source: IEEE Transactions on Biomedical Engineering - February 19, 2021 Category: Biomedical Engineering Source Type: research

Low-Frequency Impedance-Based Cell Discrimination Considering Ion Transport Model in Cell Suspension
Low-frequency impedance-based (LFI) cell discrimination as a novel non-destructive and non-invasive cell discrimination is proposed. LFI cell discrimination discriminates the cell type by considering an ion transport model in cell suspension. Ion transport model in cell suspension is constructed on the basis of Fick's laws of diffusion in the extracellular region under ion permeability P which represents the characteristics of cell type. P is achieved using the ion transport model equation through an iterative curve fitting to an ion concentration in extracellular region obtained from low-frequency impedance which i...
Source: IEEE Transactions on Biomedical Engineering - February 19, 2021 Category: Biomedical Engineering Source Type: research

Evaluation of Respiratory Muscle Activity by Means of Concentric Ring Electrodes
Surface electromyography (sEMG) can be used for the evaluation of respiratory muscle activity. Recording sEMG involves the use of surface electrodes in a bipolar configuration. However, electrocardiographic (ECG) interference and electrode orientation represent considerable drawbacks to bipolar acquisition. As an alternative, concentric ring electrodes (CREs) can be used for sEMG acquisition and offer great potential for the evaluation of respiratory muscle activity due to their enhanced spatial resolution and simple placement protocol, which does not depend on muscle fiber orientation. The aim of this work was to analyze ...
Source: IEEE Transactions on Biomedical Engineering - February 19, 2021 Category: Biomedical Engineering Source Type: research

Unified Expression of the Quasi-Static Electromagnetic Field: Demonstration With MEG and EEG Signals
Conclusion: The VSH model is a powerful and simple approach for modeling quasi-static electromagnetic fields. Significance: Our formalism provides a unified framework for interpreting resolution questions, and paves the way for new processing and analysis methods. (Source: IEEE Transactions on Biomedical Engineering)
Source: IEEE Transactions on Biomedical Engineering - February 19, 2021 Category: Biomedical Engineering Source Type: research

A Novel Estimation Approach of Pressure Gradient and Haemodynamic Stresses as Indicators of Pathological Aortic Flow Using Subvoxel Modelling
Conclusion: Our novel approach based on the modelling of subvoxel stress offers a validated and- more accurate way to estimate pressure gradient, irreversible pressure loss and SVS stress. Significance: We anticipate that the approach may potentially be applied to image-based in vivo, in vitro 4D flow data or in silico data with limited spatial resolution to assess pressure loss and SVS stresses in disturbed aortic blood flow. (Source: IEEE Transactions on Biomedical Engineering)
Source: IEEE Transactions on Biomedical Engineering - February 19, 2021 Category: Biomedical Engineering Source Type: research

Toward Minimal-Sensing Locomotion Mode Recognition for a Powered Knee-Ankle Prosthesis
Conclusion: Results thus indicate the capability of the proposed framework to achieve simultaneously accurate and low-complex LMR systems for transfemoral individuals with powered prostheses. Significance: This framework would potentially lead to less frequent clinical visits needed for sensor replacement and calibrations, which may save health care costs and the prosthesis user's time and energy. (Source: IEEE Transactions on Biomedical Engineering)
Source: IEEE Transactions on Biomedical Engineering - February 19, 2021 Category: Biomedical Engineering Source Type: research

Enhancement of Penetration of Millimeter Waves by Field Focusing Applied to Breast Cancer Detection
Conclusion: The possibility of focusing, within a lossy medium, the electromagnetic power at millimeter-wave frequencies is demonstrated. Significance: Field focusing can be a key for using millimeter waves for breast cancer detection. (Source: IEEE Transactions on Biomedical Engineering)
Source: IEEE Transactions on Biomedical Engineering - February 19, 2021 Category: Biomedical Engineering Source Type: research

Nonlinear Modeling of Cortical Responses to Mechanical Wrist Perturbations Using the NARMAX Method
Conclusion: The proposed method well determined the common characteristics across subjects in the cortical responses to wrist perturbations. Significance: It provides new insights into the human sensorimotor nervous system in response to somatosensory inputs and paves the way for future translational studies on assessments of sensorimotor impairments using our modeling approach. (Source: IEEE Transactions on Biomedical Engineering)
Source: IEEE Transactions on Biomedical Engineering - February 19, 2021 Category: Biomedical Engineering Source Type: research

Enhanced Detection of Magnetic Nanoparticles Using a Novel Microwave Ferromagnetic Resonance Imaging System
Conclusion: Similar to ferromagnetic resonance (FMR) spectroscopy, in which detection of FMR phenomena is best achieved at probing frequencies coinciding with the structural resonant frequency of a metallic cavity, these resonant frequencies of interest yield a high level of sensitivity to MNP permeability changes and are suitable for imaging within the chamber. Significance: These represent the first experimental results of a full-scale FRI system capable of detecting and eventually imaging MNPs at biologically relevant concentra- ions. (Source: IEEE Transactions on Biomedical Engineering)
Source: IEEE Transactions on Biomedical Engineering - February 19, 2021 Category: Biomedical Engineering Source Type: research

Control of Spinal Motoneurons by Feedback From a Non-Invasive Real-Time Interface
Interfacing with human neural cells during natural tasks provides the means for investigating the working principles of the central nervous system and for developing human-machine interaction technologies. Here we present a computationally efficient non-invasive, real-time interface based on the decoding of the activity of spinal motoneurons from wearable high-density electromyogram (EMG) sensors. We validate this interface by comparing its decoding results with those obtained with invasive EMG sensors and offline decoding, as reference. Moreover, we test the interface in a series of studies involving real-time feedback on...
Source: IEEE Transactions on Biomedical Engineering - February 19, 2021 Category: Biomedical Engineering Source Type: research

Non-Invasive Characterization of Atrial Flutter Mechanisms Using Recurrence Quantification Analysis on the ECG: A Computational Study
Conclusion: RQA has been shown an effective method to distinguish different AFl electrophysiological mechanisms in a non-invasive computational framework. A clinical 12-lead ECG used as proof of concept showed the value of both the simulations and the methods. Significance: The non-invasive discrimination of AFl mechanisms helps to delineate the ablation strategy, reducing time and resources required to conduct invasive cardiac mapping and ablation procedures. (Source: IEEE Transactions on Biomedical Engineering)
Source: IEEE Transactions on Biomedical Engineering - February 19, 2021 Category: Biomedical Engineering Source Type: research

A Scalable Approach to Determine Intracardiac Pressure From Mechanical Circulatory Support Device Signals
Conclusion: LVEDP can be continuously calculated using device signals without specialized characterization. Calculated LVEDP values improved upon PAC estimations and were found using a scalable and manufacturer-accessible method. Significance: This method improves upon existing LVEDP measures without the need for rigorous characterization, external calibration, or additional intervention; this allows widescale deployment of continuous LVEDP measurement f- r patients on MCS and demonstrates key considerations necessary to translate research-grade technologies. (Source: IEEE Transactions on Biomedical Engineering)
Source: IEEE Transactions on Biomedical Engineering - February 19, 2021 Category: Biomedical Engineering Source Type: research

Deriving Polarimetry Feature Parameters to Characterize Microstructural Features in Histological Sections of Breast Tissues
Conclusion: This work demonstrates the ability of PFPs to quantitatively characterize the DPFs in the H&E pathological sections of TBTs. Significance: This technique paves the way for automatic and quantitative evaluation of specific microstructural features in histopathological digitalization and computer-aided diagnosis. (Source: IEEE Transactions on Biomedical Engineering)
Source: IEEE Transactions on Biomedical Engineering - February 19, 2021 Category: Biomedical Engineering Source Type: research

Electromagnetic Actuation System for Focused Capturing of Magnetic Particles With a Half of Static Saddle Potential Energy Configuration
Targeted drug delivery using magnetic particles (MPs) and external magnets for focusing them at the diseased regions, called magnetic drug targeting (MDT), is a next-generation therapeutic method that is being continually improved. However, most existing magnetic systems cannot focus MPs in the targeted region due to there not being enough magnetic capturing force and absence of schemes to generate localized high magnetic field at the wall of the target region. This paper suggests a novel scheme to utilize half of a static saddle potential energy configuration generated using four electromagnets that not only enhances the ...
Source: IEEE Transactions on Biomedical Engineering - February 19, 2021 Category: Biomedical Engineering Source Type: research

Intraoperative Margin Assessment in Oral and Oropharyngeal Cancer Using Label-Free Fluorescence Lifetime Imaging and Machine Learning
Objective: To demonstrate the diagnostic ability of label-free, point-scanning, fiber-based Fluorescence Lifetime Imaging (FLIm) as a means of intraoperative guidance during oral and oropharyngeal cancer removal surgery. Methods: FLIm point-measurements acquired from 53 patients (n = 67893 pre-resection in vivo, n = 89695 post-resection ex vivo) undergoing oral or oropharyngeal cancer removal surgery were used for analysis. Discrimination of healthy tissue and cancer was investigated using various FLIm-derived parameter sets and classifiers (Support Vector Machine, Random Forests, CNN). Classifier outpu...
Source: IEEE Transactions on Biomedical Engineering - February 19, 2021 Category: Biomedical Engineering Source Type: research

Design and Comparison of Magnetically-Actuated Dexterous Forceps Instruments for Neuroendoscopy
Robot-assisted minimally invasive surgical (MIS) techniques offer improved instrument precision and dexterity, reduced patient trauma and risk, and promise to lessen the skill gap among surgeons. These approaches are common in general surgery, urology, and gynecology. However, MIS techniques remain largely absent for surgical applications within narrow, confined workspaces, such as neuroendoscopy. The limitation stems from a lack of small yet dexterous robotic tools. In this work, we present the first instance of a surgical robot with a direct magnetically-driven end effector capable of being deployed through a standard ne...
Source: IEEE Transactions on Biomedical Engineering - February 19, 2021 Category: Biomedical Engineering Source Type: research

A Glucose-Insulin Mixture Model and Application to Short-Term Hypoglycemia Prediction in the Night Time
Conclusion: GIM, by fusing various glucose-insulin models via Bayesian inference, has the promise to capture glucose dynamics and predict hypoglycemia. Significance: GIM based short-term hypoglycemia prediction has potential clinical utility for timely intervention. (Source: IEEE Transactions on Biomedical Engineering)
Source: IEEE Transactions on Biomedical Engineering - February 19, 2021 Category: Biomedical Engineering Source Type: research

Reconstruction of Organ Boundaries With Deep Learning in the D-Bar Method for Electrical Impedance Tomography
Conclusions and Significance: The results demonstrate that deep neural networks can successfully learn the mapping between scattering transforms and the internal boundaries of structures. (Source: IEEE Transactions on Biomedical Engineering)
Source: IEEE Transactions on Biomedical Engineering - February 19, 2021 Category: Biomedical Engineering Source Type: research

Predicting Biological Gender and Intelligence From fMRI via Dynamic Functional Connectivity
Conclusion: Our work is an important milestone for the understanding of non-stationary behavior of hemodynamic blood-oxygen level dependent (BOLD) signal in brain and how they are associated with biological gender and intelligence. Significance: The paper demonstrates that dynamic behavior of bra- n can contribute substantially towards forming a fingerprint of biological gender and intelligence. (Source: IEEE Transactions on Biomedical Engineering)
Source: IEEE Transactions on Biomedical Engineering - February 19, 2021 Category: Biomedical Engineering Source Type: research

A Direct Drive Parallel Plane Piezoelectric Needle Positioning Robot for MRI Guided Intraspinal Injection
Conclusion: The reported robot and MRI image feedback system is capable of repeatable and accurate needle guide positioning. Significance: This high accuracy will result in a significant improvement to the workflow of spinal injection procedures. (Source: IEEE Transactions on Biomedical Engineering)
Source: IEEE Transactions on Biomedical Engineering - February 19, 2021 Category: Biomedical Engineering Source Type: research

Enhanced Fast-VESTAL for Magnetoencephalography Source Imaging: From Theory to Clinical Application in Epilepsy
A novel magnetoencephalography source imaging approach called Fast Vector-based Spatio-Temporal Analysis (Fast-VESTAL) has been successfully applied in creating source images from evoked and resting-state data from both healthy subjects and individuals with neurological and/or psychiatric disorders, but its reconstructed source images may show false-positive activations, especially under low signal-to-noise ratio conditions. Here, to effectively reduce false-positive artifacts, we introduced an enhanced Fast-VESTAL (eFast-VESTAL) approach that adopts generalized second-order cone programming. We compared the spatiotemporal...
Source: IEEE Transactions on Biomedical Engineering - February 19, 2021 Category: Biomedical Engineering Source Type: research

Analysis of the RF Excitation of Endovascular Stents in Small Gap and Overlap Scenarios Using an Electro-Optical E-field Sensor
Conclusion: Electro-optic E-field measurements are a valuable tool for RF safety assessments in both single as well as coupled stents. Significance: RF induced heating of single stents during MRI has been extensively studied. However, in clinical practice often two or more stents are implanted in close proximity which can substantially change the pattern of the scattered electric fields and the localization and intensity of hot spots. In this study a detailed assessment of the coupling of stents during RF excitation is given. (Source: IEEE Transactions on Biomedical Engineering)
Source: IEEE Transactions on Biomedical Engineering - February 19, 2021 Category: Biomedical Engineering Source Type: research

Multi-Tissue Analysis on the Impact of Electroporation on Electrical and Thermal Properties
Conclusion: The three tissue types show similar electrical and thermal responses to IRE, though brain tissue exhibits the greatest differences. The results also show that tissue type plays a role in the expected ablation and thermal damage volumes. Significance: The conductivity and its changes due to heating are expected to have a marked impact on the ablation volume. Incorporating these tissue properties aids in the prediction and optimization of electroporation-based therapies. (Source: IEEE Transactions on Biomedical Engineering)
Source: IEEE Transactions on Biomedical Engineering - February 19, 2021 Category: Biomedical Engineering Source Type: research

Intensity Augmentation to Improve Generalizability of Breast Segmentation Across Different MRI Scan Protocols
Conclusion: Our results show that the proposed intensity augmentation increases segmentation performance across different datasets. Significance: The proposed method can improve whole breast segmentation of clinical MR scans acquired with different protocols. (Source: IEEE Transactions on Biomedical Engineering)
Source: IEEE Transactions on Biomedical Engineering - February 19, 2021 Category: Biomedical Engineering Source Type: research

A Wireless Implantable Passive Intra-Abdominal Pressure Sensing Scheme via Ultrasonic Imaging of a Microfluidic Device
In this article, we demonstrate a wireless and passive physiological pressure sensing scheme that utilizes ultrasound imaging of an implantable microfluidic based pressure sensitive transducer. The transducer consists of a sub-mm scale pressure sensitive membrane that covers a reservoir filled with water and is connected to a hydrophobic micro-channel. Applied pressure onto the transducer deflects the membrane and pushes the water from the reservoir into the channel; the water's travelling distance in the channel is a function of the applied pressure, which is quantitatively measured by using a 40 MHz ultrasound ima...
Source: IEEE Transactions on Biomedical Engineering - February 19, 2021 Category: Biomedical Engineering Source Type: research

Quantitative Assessment of the Airway Response to Bronchial Tests Based on a Spirometric Curve Shift
Conclusion: An unprecedented method to plausibly transforming the spirometry data into the site and degree of changes in airway properties has been proposed. Significance: The- method can be used to deduce about the effects of bronchial tests, as well as to monitor changes in the airways between visits or to investigate how inhaled pharmaceuticals affect the bronchi. (Source: IEEE Transactions on Biomedical Engineering)
Source: IEEE Transactions on Biomedical Engineering - February 19, 2021 Category: Biomedical Engineering Source Type: research

Table of Contents
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Source: IEEE Transactions on Biomedical Engineering - February 19, 2021 Category: Biomedical Engineering Source Type: research

IEEE Transactions on Biomedical Engineering Handling Editors
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Source: IEEE Transactions on Biomedical Engineering - February 19, 2021 Category: Biomedical Engineering Source Type: research

IEEE Transactions on Biomedical Engineering (T-BME)
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Source: IEEE Transactions on Biomedical Engineering - February 19, 2021 Category: Biomedical Engineering Source Type: research

IEEE Engineering in Medicine and Biology Society
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Source: IEEE Transactions on Biomedical Engineering - February 19, 2021 Category: Biomedical Engineering Source Type: research

Frontcover
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Source: IEEE Transactions on Biomedical Engineering - February 19, 2021 Category: Biomedical Engineering Source Type: research

Corrections to “A multiscale Agent-Based Model of Ductal Carcinoma in Situ”
(Source: IEEE Transactions on Biomedical Engineering)
Source: IEEE Transactions on Biomedical Engineering - January 22, 2021 Category: Biomedical Engineering Source Type: research

Hydraulically Steerable Micro Guidewire Capable of Distal Sharp Steering
Current steerable catheters or guidewires often cannot advance into small diameter vessels due to their large diameters or lack of sharp steering capacity. This paper proposes a hydraulically steerable guidewire with 400 μm diameter, which can access 1 mm diameter vessels whose branching angle is larger than 90 degrees. The designed steering mechanism consists of a flexible eccentric tube with inner micro patterns, which can bend in two different curvatures when pressurized. Its distal sharp curve of the 2 mm segment allows access to small diameter vessels because it provides a large steering angle even in confinement i...
Source: IEEE Transactions on Biomedical Engineering - January 22, 2021 Category: Biomedical Engineering Source Type: research

Real-Time Forecasting of sEMG Features for Trunk Muscle Fatigue Using Machine Learning
Conclusion: Even though the sEMG features are non-stationary and vary between subjects, adaptive learning and forecasting, especially using CNNs, can provide accurate and precise forecasts across a range of physical activities. Significance: The proposed models provide the groundwork for a wearable device which can forecast muscle fatigue in the trunk, so as to potentially prevent low back pain. Additionally, the explicit real-time forecasting of sEMG features provides a general model which can be applied to many applications of muscle activity monitoring, which helps practitioners and physiotherapists improve therapy. (So...
Source: IEEE Transactions on Biomedical Engineering - January 22, 2021 Category: Biomedical Engineering Source Type: research

Dual-Function MR-Guided Hyperthermia: An Innovative Integrated Approach and Experimental Demonstration of Proof of Principle
Temperature monitoring plays a central role in improving clinical effectiveness of adjuvant hyperthermia. The potential of magnetic resonance thermometry for treatment monitoring purposes led to several MR-guided hyperthermia approaches. However, the proposed solutions were sub-optimal due to technological and intrinsic limitations. These hamper achieving target conformal heating possibilities (applicator limitations) and accurate thermometry (inadequate signal-to-noise-ratio (SNR)). In this work, we studied proof of principle of a dual-function hyperthermia approach based on a coil array (64 MHz, 1.5 T) that is ...
Source: IEEE Transactions on Biomedical Engineering - January 22, 2021 Category: Biomedical Engineering Source Type: research

A Long-Term Cranial Window for High-Resolution Photoacoustic Imaging
Conclusion: The cranial window has a good imaging quality for both anesthetized and behaving rats, enabling long-term, high-resolution, and steady photoacoustic imaging of cerebral vasculatures. Significance: Based on the studies of both anesthetized and behaving rats, the proposed cranial window has the potential to be used in the longitudinal in vivo study of chronic brain diseases in freely moving rodents. (Source: IEEE Transactions on Biomedical Engineering)
Source: IEEE Transactions on Biomedical Engineering - January 22, 2021 Category: Biomedical Engineering Source Type: research

Voluntary Control of an Ankle Joint Exoskeleton by Able-Bodied Individuals and Stroke Survivors Using EMG-Based Admittance Control Scheme
Control schemes based on electromyography (EMG) have demonstrated their superiority in human-robot cooperation due to the fact that motion intention can be well estimated by EMG signals. However, there are several limitations due to the noisy nature of EMG signals and the inaccuracy of EMG-force/torque estimation, which might deteriorate the stability of human-robot cooperation movement. To improve the movement stability, an EMG-based admittance control scheme (EACS) was proposed, comprised of an EMG-driven musculoskeletal model (EDMM), an admittance filter and an inner position controller. To investigate the performance o...
Source: IEEE Transactions on Biomedical Engineering - January 22, 2021 Category: Biomedical Engineering Source Type: research

Skill-Oriented and Performance-Driven Adaptive Curricula for Training in Robot-Assisted Surgery Using Simulators: A Feasibility Study
This study introduces an automatic, adaptive curriculum where the training session is real-time scheduled on the basis of the trainee's performances. Methods: An experimental study using the master console of the da Vinci Research Kit (Intuitive Surgical Inc., Sunnyvale, US) was carried out to test this approach. Tasks involving fundamental skills of robotic surgery were designed and simulated in VR. Twelve participants without medical background along with twelve medical residents were randomly and equally divided into two groups: a control group, self-managing the training session, and an experimental group, under...
Source: IEEE Transactions on Biomedical Engineering - January 22, 2021 Category: Biomedical Engineering Source Type: research

Dimensionality Transcending: A Method for Merging BCI Datasets With Different Dimensionalities
Conclusion and significance: Such findings pave the way to a new generation of BCI systems capable of reusing information and learning from several sources of data despite differences in their electrodes positioning. (Source: IEEE Transactions on Biomedical Engineering)
Source: IEEE Transactions on Biomedical Engineering - January 22, 2021 Category: Biomedical Engineering Source Type: research

Classifying Major Depressive Disorder and Response to Deep Brain Stimulation Over Time by Analyzing Facial Expressions
Conclusion: This work demonstrates the potential for the classification of MDD remission and response to DBS treatment from passively acquired video captured during unstructured, unscripted psychiatric interviews. Significance: This novel MDD evaluation could be used to augment current psychiatric evaluations and allow automatic, low-cost, frequent use when an expert isn’t readily available or the patient is unwilling or unable to engage. Potentially, the framework may also be applied to other psychiatric disorders. (Source: IEEE Transactions on Biomedical Engineering)
Source: IEEE Transactions on Biomedical Engineering - January 22, 2021 Category: Biomedical Engineering Source Type: research

Temporal-Framing Adaptive Network for Heart Sound Segmentation Without Prior Knowledge of State Duration
Conclusion: TFAN therefore provides a substantial improvement on heart sound segmentation while using less parameters compared to BiGRNN. Significance: The proposed method is highly flexible and likely to apply to other non-stationary time series. Further work is required to understand to what extent this approa- h will provide improved diagnostic performance, although it is logical to assume superior segmentation will lead to improved diagnostics. (Source: IEEE Transactions on Biomedical Engineering)
Source: IEEE Transactions on Biomedical Engineering - January 22, 2021 Category: Biomedical Engineering Source Type: research

Sleep-Dependent Directional Interactions of the Central Nervous System-Cardiorespiratory Network
Conclusion: These findings reveal detailed information regarding CNS-cardiorespiratory interactions during sleep and provide new insights into understanding of sleep control mechanisms. Significance: Our approach may facilitate the investigation of the pathological cardiorespiratory complications of sleep disorders. (Source: IEEE Transactions on Biomedical Engineering)
Source: IEEE Transactions on Biomedical Engineering - January 22, 2021 Category: Biomedical Engineering Source Type: research

Muscle Path Wrapping on Arbitrary Surfaces
Conclusion: Our method has been implemented in the open source simulation system ArtiSynth (www.artisynth.org) and helps solve the problem of muscle wrapping around bones and other structures. Significance: Muscle wrapping on arbitrary surfaces opens up new possibilities for patient-specific musculoskeletal models where muscle paths can directly conform to shapes extracted from medical image data. (Source: IEEE Transactions on Biomedical Engineering)
Source: IEEE Transactions on Biomedical Engineering - January 22, 2021 Category: Biomedical Engineering Source Type: research