Filtered By:
Condition: Metabolic Syndrome
Education: Study

This page shows you your search results in order of relevance. This is page number 5.

Order by Relevance | Date

Total 657 results found since Jan 2013.

Metabolic health is more closely associated with prevalence of cardiovascular diseases or stroke than obesity: A cross-sectional study in Korean populations
Abstract: Mounting evidence suggests that not all obese subjects are at increased cardiovascular risk. However, the relationship between the metabolically healthy obese (MHO) phenotype and cardiovascular diseases (CVDs) or stroke remains unclear. Therefore, we retrospectively investigated the prevalence of CVDs or stroke according to metabolic health with obese. We studied 3695 subjects (40–85 years) from the Fifth Korean National Health and Nutrition Examination Survey. Participants were divided into 2 groups and 6 subgroups based on the body mass index (BMI) and metabolic syndrome (MetS) components: healthy (exhibitin...
Source: Medicine - June 1, 2016 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research

The Relationship between Metabolically Obese Non-Obese Weight and Stroke: The Korea National Health and Nutrition Examination Survey
This study aimed to compare the prevalence of stroke in MONW and MHO individuals. MethodsA total of 25,744 subjects aged ≥40 years were selected from the 2007–2014 Korean National Health and Nutrition Examination Survey. MetS was defined using 2001 National Cholesterol Education Program/Adult Treatment Panel III and 2005 American Heart Association/National Heart, Lung, and Blood Institute criteria. Non-obese weigh t and obesity were defined as a body mass index (BMI)
Source: PLoS One - August 4, 2016 Category: Biomedical Science Authors: Young-Gyun Seo Source Type: research

Metabolic syndrome is associated with cognitive impairment after transient ischemic attack/mild stroke, but does not affect cognitive recovery in short term
The metabolic syndrome (MetS) is a cluster of risk factors for cognitive impairment. We aimed to investigate the association between MetS and risk of persistent cognitive impairment in patients with a transient ischemic attack (TIA) or mild ischemic stroke. This is a prospective and observational study in consecutive patients with first-ever TIA or mild stroke (National Institutes of Health Stroke Scale score ≤ 6). Patients underwent Montreal cognitive assessment (MoCA) at hospital admission and day 30 after discharge. We defined cognitive impairment as a MoCA score of ≤26. Persistent cognitive impairment was defin...
Source: NeuroReport - July 30, 2020 Category: Neurology Tags: Clinical Neuroscience Source Type: research

Crocins for Ischemic Stroke: A Review of Current Evidence
Crocins (CRs) and the related active constituents derived from Crocus sativus L. (Saffron) have demonstrated protective effects against cerebral ischemia and ischemic stroke, with various bioactivities including neuroprotection, anti-neuroinflammation, antioxidant, and cardiovascular protection. Among CRs, crocin (CR) has been shown to act on multiple mechanisms and signaling pathways involved in ischemic stroke, including mitochondrial apoptosis, nuclear factor kappa light chain enhancer of B cells pathway, S100 calcium-binding protein B, interleukin-6 and vascular endothelial growth factor-A. CR is generally safe and wel...
Source: Frontiers in Pharmacology - August 5, 2022 Category: Drugs & Pharmacology Source Type: research

Determinants of metabolic syndrome and its prognostic implications among stroke patients in Africa: Findings from the Stroke Investigation Research Network (SIREN) study
This study aimed to investigate the determinants of METS and its prognostic implications among Africans with newly diagnosed stroke in the SIREN study.
Source: Journal of the Neurological Sciences - August 8, 2022 Category: Neurology Authors: Abiodun M. Adeoye, Adeseye A. Akintunde, Joshua Akinyemi, Adekunle G. Fakunle, Fred S. Sarfo, Albert Akpalu, Kolawole Wahab, Reginald Obiako, Morenikeji Komolafe, Lukman Owolabi, Godwin O. Osaigbovo, Onoja Akpa, Oyedunni Arulogun, Akinkunmi P. Okekunle, O Source Type: research

Telmisartan Promotes Potential Glucose Homeostasis in Stroke-Resistant Spontaneously Hypertensive Rats via Peroxisome Proliferator-Activated Receptor γ Activation.
Abstract An angiotensin 2 type 1 receptor blocker (ARB) telmisartan possesses not only an anti-hypertensive effect but also an anti-metabolic syndrome effect due to peroxisome proliferator-activated receptor γ (PPAR-γ) activation. In the present study, we examined the effects of telmisartan on the angiotensin 2 type 1 receptor (AT1R), PPAR-γ, and insulin receptor (IR) in stroke-resistant spontaneously hypertensive rats (SHR-SR), comparing them with Wistar rats. Three-months-old SHR-SR rats were divided into three treatment groups, i.e., vehicle (SHR/Ve), low-dose telmisartan (0.3 mg/kg/day, SHR/Low), and high-d...
Source: Current Neurovascular Research - January 4, 2015 Category: Neurology Authors: Omote Y, Deguchi K, Kurata T, Yamashita T, Sato K, Hishikawa N, Abe K Tags: Curr Neurovasc Res Source Type: research

Relationship Between Insulin-like Growth Factor Binding Protein-2 and Left Ventricular Stroke Volume in Patients with Aortic Stenosis
Conclusions In this study, we documented that lower IGFBP-2 levels are independently associated with lower SVi, a powerful predictor of worse outcomes in the mild to moderate AS population. Teaser In aortic stenosis (AS) patients, LV remodeling and function vary extensively from one patient to another. Considering the associations between circulating IGFBP-2 and markers of the metabolic syndrome, the aim of the study was to examine the relationship between circulating IGFBP-2 and left ventricle (LV) pump function as measured by stroke volume index in AS patients with preserved LV ejection fraction.
Source: Canadian Journal of Cardiology - April 30, 2015 Category: Cardiology Source Type: research

Metabolic syndrome correlates poorly with cognitive performance in stroke-free community-dwelling older adults: a population-based, cross-sectional study in rural Ecuador.
CONCLUSIONS: This population-based study showed a poor correlation of metabolic syndrome with cognitive performance after adjusting for relevant confounders. Of the individual components of metabolic syndrome, only hypertriglyceridemia correlated with worse cognitive performance. PMID: 26142624 [PubMed - as supplied by publisher]
Source: Aging Clinical and Experimental Research - July 5, 2015 Category: Geriatrics Authors: Del Brutto OH, Mera RM, Zambrano M Tags: Aging Clin Exp Res Source Type: research

The effect of metabolic syndrome and obesity on outcomes of acute ischemic stroke patients treated with systemic thrombolysis
Metabolic syndrome (MetS) is associated with increased risk of ischemic stroke; while central obesity has controversial effects on ischemic stroke. We investigated effects of MetS and obesity on clinical courses and outcomes of patients treated with intravenous recombinant tissue-type plasminogen activator (iv rt-PA). 319 patients treated with intravenous thrombolysis were included to our study. Metabolic syndrome was determined if ≥3 of following criteria are present: elevated waist circumference; elevated triglycerides; reduced high density-lipoprotein cholesterol (HDL-C); elevated blood pressure; elevated fasting glucose.
Source: Journal of the Neurological Sciences - October 10, 2017 Category: Neurology Authors: Demet Funda Bas, Atilla Ozcan Ozdemir Source Type: research

Common comorbidities and survival in MS: Risk for stroke, type 1 diabetes and infections
Conclusions Given the high risk for stroke in this MS population and the observed complexity among the coincident common risk factors for circulatory diseases, the high risk for type 1 diabetes and common infections raise a need to recognize patients at risk with these conditions and with the other known risk factors such as metabolic syndrome and smoking. The survival disadvantage related to circulatory diseases observed in general population is true also in MS and should be recognized to reduce the burden of disease and premature mortality in MS. Graphical abstract
Source: Multiple Sclerosis and Related Disorders - November 13, 2017 Category: Neurology Source Type: research

Polymorphism of IL6 receptor gene is associated with ischaemic stroke in patients with metabolic syndrome.
Abstract The interleukin 6 receptor (IL6R) gene has been shown to locate in the chromosome 1q21 associated with metabolic syndrome (MetS), a condition related to the augmented risk of ischaemic stroke (IS), cardiovascular diseases and all-cause mortality. The aim of this study was to assess the relationship between IL6R gene polymorphisms and IS in patients with MetS in the Chinese Han population. We designed a case-control study enrolling 447 patients with MetS plus IS and 438 patients with MetS alone. Tag single nucleotide polymorphisms (SNPs) of the IL6R gene were determined by a fine-mapping strategy and genot...
Source: Brain Research - December 9, 2019 Category: Neurology Authors: Huang X, Ye Q, Zhu Z, Chen W, Chen Y, Li J, Chen S, Xia N, Huang X, Ye Z Tags: Brain Res Source Type: research

TG/HDL-C ratio as a predictor of stroke in the population with healthy BMI: The Jichi Medical School Cohort Study
This study examined whether TG/HDL-C helps in predicting stroke onset; this was compared between the whole population and healthy body mass index (BMI) population.
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - May 15, 2022 Category: Nutrition Authors: Fumitaka Sato, Yosikazu Nakamura, Kazunori Kayaba, Shizukiyo Ishikawa Source Type: research

Use of Total Cerebral Blood Flow as an Imaging Biomarker of Known Cardiovascular Risks Clinical Sciences
Conclusions— Reduced cerebral blood flow seems to be a correlate of vascular disease risk factors associated with cardiometabolic dysregulation. Cerebral blood flow may provide a valid imaging biomarker for cardiovascular risk.
Source: Stroke - August 26, 2013 Category: Neurology Authors: Jennings, J. R., Heim, A. F., Kuan, D. C.-H., Gianaros, P. J., Muldoon, M. F., Manuck, S. B. Tags: Cerebrovascular disease/stroke, Computerized tomography and Magnetic Resonance Imaging Clinical Sciences Source Type: research

Habitual snoring and risk of stroke: A meta-analysis of prospective studies
Habitual snoring (HS), which is defined as snoring more than three nights per week, occurs among approximately 33% of the general population [1]. Emerging evidence suggests this increase in HS problems may be due to hypertension [2], diabetes mellitus [3], metabolic syndrome [4], and intima-media thickness (IMT) [5]. In addition, there was mounting evidence for an association between HS and cardiovascular and all-cause mortality [6–8]. However, the role of HS in stroke is still uncertain.
Source: International Journal of Cardiology - March 11, 2015 Category: Cardiology Authors: Min Li, Kun Li, Xiao-Wei Zhang, Wen-Shang Hou, Zhen-Yu Tang Tags: Letter to the Editor Source Type: research

Omentin-1 and risk of myocardial infarction and stroke: Results from the EPIC-Potsdam cohort study
The recently identified adipokine omentin-1 is inversely associated with body fatness, metabolic syndrome and cardiovascular disease (CVD) in cross-sectional analyses. However, prospective data on the association between plasma omentin-1 levels and future risk of CVD are lacking. The aim of the study was to investigate the relationship between omentin-1 and incident myocardial infarction (MI) and stroke.
Source: Atherosclerosis - June 1, 2016 Category: Cardiology Authors: Juliane Menzel, Romina di Giuseppe, Ronald Biemann, Clemens Wittenbecher, Krasimira Aleksandrova, Tobias Pischon, Andreas Fritsche, Matthias B. Schulze, Heiner Boeing, Berend Isermann, Cornelia Weikert Source Type: research