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Condition: Metabolic Syndrome
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Total 657 results found since Jan 2013.

Food Intake Does Not Differ between Obese Women Who Are Metabolically Healthy or Abnormal Nutritional Epidemiology
Conclusions: Healthy obesity was not associated with a healthier diet. Prospective studies on relations of dietary patterns, which may be a better indicator of usual diet, with the phenotype would be beneficial.
Source: Journal of Nutrition - November 19, 2014 Category: Nutrition Authors: Kimokoti, R. W., Judd, S. E., Shikany, J. M., Newby, P. Tags: Nutritional Epidemiology Source Type: research

Cigarette smoking has a positive and independent effect on testosterone levels.
Authors: Wang W, Yang X, Liang J, Liao M, Zhang H, Qin X, Mo L, Lv W, Mo Z Abstract Previous studies have suggested that testosterone levels are linked to a variety of diseases, such as cardiovascular disease, type-2 diabetes, the metabolic syndrome, erectile dysfunction, depression, stroke and osteoporosis. Since cigarette smoking is a major health problem and highly prevalent among men, several groups have studied the effects of cigarette smoking on testosterone levels in men. However, the results have been conflicting. Our objectives were to examine the association of cigarette smoking and serum levels of sex ho...
Source: Hormones - December 2, 2014 Category: Endocrinology Tags: Hormones (Athens) Source Type: research

LOX-1 in atherosclerotic disease.
Abstract Oxidized low-density lipoprotein (LDL) exhibits various biological activities and accumulates in atheromas. LOX-1 (lectin-like oxidized LDL receptor) is the receptor that mediates oxidized LDL activity in vascular endothelial cells. Activation of LOX-1 results in oxidized LDL-induced endothelial dysfunction and hyperlipidemia-induced vascular lipid deposition. We hypothesized that LOX-1 is a candidate risk factor beyond LDL cholesterol (LDLC) and developed a novel assay to quantify LOX-1 ligand containing apoB (LAB). In men from the United States, serum LAB showed a significant positive association with c...
Source: International Journal of Clinical Chemistry - November 22, 2014 Category: Chemistry Authors: Sawamura T, Wakabayashi I, Okamura T Tags: Clin Chim Acta Source Type: research

Serum uric acid and cardiovascular risk: State of the art and perspectives
In this report, we review the inextricably link of serum uric acid to known cardiovascular risk factors, and we describe the possible mechanisms and potential causative role between serum uric acid and cardiovascular events in the general population, in subjects with cardiovascular risk factors and in those with pre-existing cardiovascular diseases. Limited information however is available concerning the impact of urate-lowering treatments on cardiovascular events, whereas only a positive therapeutic trial could give definite answers to the difficult problem of causality of uric acid in relation to cardiovascular risk. Thu...
Source: Joint Bone Spine - December 7, 2014 Category: Orthopaedics Source Type: research

Associations of neighborhood area level deprivation with the metabolic syndrome and inflammation among middle- and older- age adults
Background: The study examines the association of neighborhood socioeconomic deprivation and metabolic syndrome with inflammation. Methods: The analysis included 19, 079 black and white participants from the REasons for Geographic And Racial Differences in Stroke Study who were age> 45 years at baseline. Logistic regression examined whether neighborhood deprivation was associated with increased odds of METS and CRP-MetS. Results: Among black adults, residing in the most deprived neighborhoods was associated with increased odds of obesity (p
Source: BMC Public Health - December 23, 2014 Category: Consumer Health News Authors: Akilah KeitaSuzanne JuddVirginia HowardApril CarsonJamy ArdJose Fernandez Source Type: research

C-reactive protein: Its correlations with pulmonary function, physical capacity and anthropometric measurements in patients with metabolic syndrome
Conclusions: It was found negative relationships between CRP level with PF and PC. On the contrary, there were positive correlations of CRP with parameters of BC. We think that it can be provided decline in the CRP level and increment in PF improving the functional capacity and body composition with aerobic exercise in patients with MS.
Source: European Respiratory Journal - December 23, 2014 Category: Respiratory Medicine Authors: Demirtas, R. N., Bozdemir Ozel, C., Arikan, H., Calik-Kutukcu, E., Saglam, M., Vardar-Yagli, N., Celer, O., Akalin, A., Alatas, F. Tags: 9.2 Physiotherapists Source Type: research

LOX-1 in atherosclerotic disease
Publication date: 2 February 2015 Source:Clinica Chimica Acta, Volume 440 Author(s): Tatsuya Sawamura , Ichiro Wakabayashi , Tomonori Okamura Oxidized low-density lipoprotein (LDL) exhibits various biological activities and accumulates in atheromas. LOX-1 (lectin-like oxidized LDL receptor) is the receptor that mediates oxidized LDL activity in vascular endothelial cells. Activation of LOX-1 results in oxidized LDL-induced endothelial dysfunction and hyperlipidemia-induced vascular lipid deposition. We hypothesized that LOX-1 is a candidate risk factor beyond LDL cholesterol (LDLC) and developed a novel assay to quantify...
Source: Clinica Chimica Acta - January 11, 2015 Category: Laboratory Medicine Source Type: research

The brighter (and evolutionarily older) face of the metabolic syndrome: evidence from Trypanosoma Cruzi infection in CD‐1 mice
This article is protected by copyright. All rights reserved.
Source: Diabetes/Metabolism Research and Reviews - January 1, 2015 Category: Endocrinology Authors: Wunnie Brima, Daniel J. Eden, Syed Faizan Mehdi, Michelle Bravo, Mohammad M. Wiese, Joanna Stein, Vanessa Almonte, Dazhi Zhao, Irwin Kurland, Jeffrey E. Pessin, Tomas Zima, Herbert B. Tanowitz, Louis M. Weiss, Jesse Roth, Fnu Nagajyothi Tags: Research Article Source Type: research

Making one change — getting more fiber — can help with weight loss
Getting to a healthy weight and staying there is an important way to prevent heart disease, diabetes, some cancers, and other serious conditions. Many of us know firsthand just how hard it can be to reach and maintain that healthy weight. And there’s no shortage of ways to try to get there: You can count calories, carbs, or points. You can cut back on fat or sugar. You can try any number of popular diets that forbid certain foods, or focus on just one (the grapefruit diet, anyone?). Any of these approaches might work for you. Or they might not — in large part because they are complicated. A study published in todayR...
Source: New Harvard Health Information - February 17, 2015 Category: Consumer Health News Authors: Nancy Ferrari Tags: Diet and Weight Loss Healthy Eating fiber Source Type: news

Emerging cardiovascular indications of mineralocorticoid receptor antagonists.
Abstract Mineralocorticoid receptor (MR) antagonism is a well-established treatment modality for patients with hypertension, heart failure, and left ventricular systolic dysfunction (LVSD) post-myocardial infarction (MI). There are emerging data showing potential benefits of MR antagonists in other cardiovascular conditions. Studies have shown association between MR activation and the development of myocardial fibrosis, coronary artery disease, metabolic syndrome, and cerebrovascular diseases. This review examines the preclinical and clinical data of MR antagonists for novel indications including heart failure wit...
Source: Trends in Endocrinology and Metabolism: TEM - February 20, 2015 Category: Endocrinology Authors: Parviz Y, Iqbal J, Pitt B, Adlam D, Al-Mohammad A, Zannad F Tags: Trends Endocrinol Metab Source Type: research

Multiple biomarker models for improved risk estimation of specific cardiovascular diseases related to metabolic syndrome: a cross-sectional study
Conclusion: The reduced joint association modeling results suggest that unique combinations of biomarkers with their related measure of association can be used to produce more accurate cumulative risk estimates for each CVD. Additionally, our results indicate that the use of multiple biomarkers in a single multivariate model may provide increased accuracy of individual biomarker association estimates by controlling for statistical artifacts and spurious relationships due to co-biomarker confounding.
Source: Population Health Metrics - March 14, 2015 Category: Epidemiology Authors: Evan CoffmanJennifer Richmond-Bryant Source Type: research

Emerging cardiovascular indications of mineralocorticoid receptor antagonists
Publication date: April 2015 Source:Trends in Endocrinology & Metabolism, Volume 26, Issue 4 Author(s): Yasir Parviz , Javaid Iqbal , Bertram Pitt , David Adlam , Abdallah Al-Mohammad , Faiez Zannad Mineralocorticoid receptor (MR) antagonism is a well-established treatment modality for patients with hypertension, heart failure, and left ventricular systolic dysfunction (LVSD) post-myocardial infarction (MI). There are emerging data showing potential benefits of MR antagonists in other cardiovascular conditions. Studies have shown association between MR activation and the development of myocardial fibrosis, corona...
Source: Trends in Endocrinology and Metabolism - March 31, 2015 Category: Endocrinology Source Type: research

Treatment and survival of non-alcoholic steatohepatitis associated hepatocellular carcinoma
Background: The incidence of non-alcoholic steatohepatitis (NASH) is increasing worldwide and a poorly defined subset of patients develops end-stage liver disease and hepatocellular carcinoma (HCC). Differences in the biological behaviour, tumour characteristics, associated risk factors, treatment outcomes and overall survival of patients with NASH-HCC remain poorly defined. The aim of this study was to determine and analyze these differences in a large clinical cohort to guide treatment decisions. Methods: 1119 patients with HCC treated in an 11 year period at the University Medical Centre of the Johannes Gutenberg Unive...
Source: BMC Cancer - April 1, 2015 Category: Cancer & Oncology Authors: Arndt WeinmannYvonne AltSandra KochCarina NellesChristoph DüberHauke LangGerd OttoTim ZimmermannJens MarquardtPeter GalleMarcus WörnsJörn Schattenberg Source Type: research

Closing the loop on inflammation and atherothrombosis: why perform the CIRT and CANTOS trials?
Authors: Ridker PM Abstract Inflammation contributes to all phases of the atherothrombotic process, patients with elevated inflammatory biomarkers such as high-sensitivity C-reactive protein (hsCRP) have increased cardiovascular risk, and recent work directly implicates the interleukin-1 (IL-1) and interleukin-6 (IL-6) pathways in atherogenesis. Yet, it remains unknown whether targeted inhibition of inflammation will reduce cardiovascular event rates. To address directly this fundamental hypothesis, our research group has initiated two large-scale, randomized, placebo-controlled trials using targeted anti-inflammat...
Source: Transactions of the American Clinical and Climatological Association - June 4, 2015 Category: Journals (General) Tags: Trans Am Clin Climatol Assoc Source Type: research

The metabolic syndrome in hypertensive black population of South Algeria.
CONCLUSION: The MS is highly prevailing among hypertensive black population, and significantly higher among women. The ranking of the cluster elements frequency shows clearly the specifities of our population. It is necessary to elaborate an adequate strategy to prevent such cardiovascular morbidity and mortality. PMID: 26044305 [PubMed - as supplied by publisher]
Source: Annales de Cardiologie et d'Angeiologie - June 1, 2015 Category: Cardiology Authors: Bachir Cherif A, Temmar M, Chibane A, Labat C, Atif ML, Taleb A, Benetos A, Bouafia MT Tags: Ann Cardiol Angeiol (Paris) Source Type: research