Modified Rheumatoid Arthritis Impact of Disease (RAID) Score, a Potential Tool for Depression and Anxiety Screening for Rheumatoid Arthritis
Publication date: Available online 5 May 2019Source: Joint Bone SpineAuthor(s): Khai-Jing Ng, Kuang-Yung Huang, Chien-Hsueh Tung, Bao-Bao Hsu, Cheng-Han Wu, Malcolm Koo, Chia-Wen Hsu, Ming-Chi Lu, Ning-Sheng Lai (Source: Joint Bone Spine)
Source: Joint Bone Spine - May 5, 2019 Category: Orthopaedics Source Type: research

Rheumatology residency in France: an assessment of the past and the unknowns of a new reform
Publication date: Available online 5 May 2019Source: Joint Bone SpineAuthor(s): Olivier Fogel, Samuel Bitoun, on behalf of the young rheumatologist’s section of the French Society of Rheumatology, (REF) (Source: Joint Bone Spine)
Source: Joint Bone Spine - May 5, 2019 Category: Orthopaedics Source Type: research

Importance of feelings of injustice in fibromyalgia, large internet survey on experiences of 4516 french patients
Publication date: Available online 5 May 2019Source: Joint Bone SpineAuthor(s): Françoise Laroche, Julien Guérin, Joël d AP Trouvin, Serge Perrot (Source: Joint Bone Spine)
Source: Joint Bone Spine - May 5, 2019 Category: Orthopaedics Source Type: research

Winds of change in imaging of calcium crystal deposition diseases
Publication date: Available online 5 May 2019Source: Joint Bone SpineAuthor(s): Fabio Becce, Anais Viry, Lisa K. Stamp, Tristan Pascart, Jean-François Budzik, MARS Collaboration, Aamir Raja (Source: Joint Bone Spine)
Source: Joint Bone Spine - May 5, 2019 Category: Orthopaedics Source Type: research

HLA-B*51 subtypes molecular analysis in a series of Italian patients with Behçet’s syndrome
Publication date: Available online 5 May 2019Source: Joint Bone SpineAuthor(s): Pietro Leccese, Maria Carmela Padula, Eustachio Vincenzo Santospirito, Rosa Colucci, Nancy Lascaro, Salvatore D’Angelo (Source: Joint Bone Spine)
Source: Joint Bone Spine - May 5, 2019 Category: Orthopaedics Source Type: research

Screening for psoriatic arthritis: targeting phenotypes may improve case detection
Publication date: Available online 5 May 2019Source: Joint Bone SpineAuthor(s): Rafic Baddoura, Antoine Ghanem, Eugenie Halaby, Boutros Soutou, Roland Tomb (Source: Joint Bone Spine)
Source: Joint Bone Spine - May 5, 2019 Category: Orthopaedics Source Type: research

Structural Progression in Axial Spondyloarthritis
Publication date: Available online 5 May 2019Source: Joint Bone SpineAuthor(s): Krystel Aouad, Nelly Ziade, Xenofon BaraliakosAbstractFunctional disability in axial spondyloarthritis is related to the structural progression caused by the disease, thus largely contributing to its global burden and still representing a major challenge in management. Diagnosis at an early inflammatory stage of the disease is the hallmark for a better disease control and management. The natural history of axial spondyloarthritis is now better understood with imaging studies and long-term follow-up data, with some predictive factors for structu...
Source: Joint Bone Spine - May 5, 2019 Category: Orthopaedics Source Type: research

Partners and nurses’ knowledge and representations of gout: a qualitative study
Conclusion: Partners and nurses’ knowledge of gout is based on daily experiences. Participants were eager to learn more about gout. Nurses’ education and education programs including partners may improve gout management and patient adherence to treatment. (Source: Joint Bone Spine)
Source: Joint Bone Spine - May 5, 2019 Category: Orthopaedics Source Type: research

Editorial Board
Publication date: May 2019Source: Joint Bone Spine, Volume 86, Issue 3Author(s): (Source: Joint Bone Spine)
Source: Joint Bone Spine - May 2, 2019 Category: Orthopaedics Source Type: research

Contents
Publication date: May 2019Source: Joint Bone Spine, Volume 86, Issue 3Author(s): (Source: Joint Bone Spine)
Source: Joint Bone Spine - May 2, 2019 Category: Orthopaedics Source Type: research

Serum retinol-binding protein 4 is associated with insulin resistance in patients with early and untreated rheumatoid arthritis
In this study, 403 individuals with newly diagnosed and untreated RA were consecutively recruited. We calculated the Disease Activity Score assessed using 28-joint counts for swelling and tenderness (DAS28). Levels of serum RBP4, interleukin-6 (IL-6) and tumor necrosis factor (TNF) α were tested. IR was defined as Homeostasis model assessment for insulin resistance (HOMA-IR) index greater than or equal 2.40.ResultsIn those 403 patients, 68 (16.9%) were male and the median age was 43 years (IQR: 36–52). There was an evidently positive correlation between increased serum levels of RBP4 and increasing sever...
Source: Joint Bone Spine - May 2, 2019 Category: Orthopaedics Source Type: research

Vitamin D Supplementation in France in Patients with or at Risk for Osteoporosis: Recent Data and New Practices
Publication date: Available online 30 April 2019Source: Joint Bone SpineAuthor(s): Jean-Claude Souberbielle, Catherine Cormier, Etienne Cavalier, Véronique Breuil, Françoise Debiais, Patrice Fardellone, Pascal Guggenbuhl, Rose-Marie-Javier, Erick Legrand, Eric Lespessailles, Julien Paccou, Thierry Thomas, Bernard Cortet, au nom du Groupe de recherche et d’information sur les ostéoporoses, (GRIO)AbstractWith intermittent vitamin D supplementation, serum 25-hydroxyvitamin D (25OHD) levels may remain stable only if the dosing interval is shorter than 3 months, the ideal perhaps being about 1 month. ...
Source: Joint Bone Spine - May 2, 2019 Category: Orthopaedics Source Type: research

Is prediction of clinical response to methotrexate in individual rheumatoid arthritis patients possible? A systematic literature review
Conclusions:No predictors were identified reliably predicting clinical response to methotrexate after 3 to 6 months in the individual patient: clinical predictors were weak. However, a promising epigenetic model was found that needs further validation. (Source: Joint Bone Spine)
Source: Joint Bone Spine - April 13, 2019 Category: Orthopaedics Source Type: research

There is no season for infectious spondylodiscitis
Publication date: Available online 11 April 2019Source: Joint Bone SpineAuthor(s): Dubost Jean-Jacques, Pereira Bruno, Couderc Marion, Soubrier Martin (Source: Joint Bone Spine)
Source: Joint Bone Spine - April 13, 2019 Category: Orthopaedics Source Type: research

Uptrend in mortality from systemic connective tissue diseases: a joinpoint regression analysis among the general population of Brazil, 1996-2016
Publication date: Available online 11 April 2019Source: Joint Bone SpineAuthor(s): Rodrigo Rezende, Carol Vieira, Ronaldo Gismondi, Evandro Klumb (Source: Joint Bone Spine)
Source: Joint Bone Spine - April 13, 2019 Category: Orthopaedics Source Type: research

Esophagus type cervical spondylosis
Publication date: Available online 11 April 2019Source: Joint Bone SpineAuthor(s): Hecheng Ma, Si Meng (Source: Joint Bone Spine)
Source: Joint Bone Spine - April 13, 2019 Category: Orthopaedics Source Type: research

Biological secondary contributors to osteoporosis in fractured patients, is an early systematic assay relevant?
Publication date: Available online 9 April 2019Source: Joint Bone SpineAuthor(s): Pierre-Emmanuel Cailleaux, David Biau, Leclerc Philippe, Anract Philippe, Roux Christian, Briot KarineAbstractObjective:To evaluate the prevalence of biological abnormalities leading to secondary osteoporosis in recently fractured patients.Methods:Adults older than 50, hospitalized for a nonvertebral fracture from July 2015 to October 2016, were assessed for bone fragility contributors in the Orthopedics Department. Bone mineral density (BMD) measurements and Vertebral Fracture assessment (VFA) were performed within 3 months. We assessed the ...
Source: Joint Bone Spine - April 11, 2019 Category: Orthopaedics Source Type: research

Polymyalgia rheumatica occurrence under multikinase inhibitors (sorafenib and erlotinib) treatment
Publication date: Available online 27 March 2019Source: Joint Bone SpineAuthor(s): Frank Verhoeven, Delphine Weil-Verhoeven, Clément Prati, Vincent Di Martino, Daniel Wendling (Source: Joint Bone Spine)
Source: Joint Bone Spine - April 6, 2019 Category: Orthopaedics Source Type: research

Early Clinical Response and Long-Term Radiographic Progression in Recent-Onset Rheumatoid Arthritis: Clinical Remission within Six Months Remains the Treatment Target
Publication date: Available online 27 March 2019Source: Joint Bone SpineAuthor(s): Julie Legrand, Thomas Kirchgesner, Tatiana Sokolova, Bruno Vande Berg, Patrick DurezAbstractObjectives: The primary objective was to evaluate the correlation between 5-year radiographic structural disease progression and early clinical remission in recent-onset rheumatoid arthritis (RA). The secondary objective was to assess the correlation between erosion development in joints free of damage at baseline and early clinical remission.Methods: A single-center retrospective study was performed in 133 patients meeting ACR criteria for RA of rece...
Source: Joint Bone Spine - March 28, 2019 Category: Orthopaedics Source Type: research

Rate of remission among rheumatoid arthritis patients being treated by rheumatologists in routine practice
Publication date: Available online 27 March 2019Source: Joint Bone SpineAuthor(s): Dubost Jean-Jacques, Pereira Bruno, Fan Angélique, Soubrier Martin (Source: Joint Bone Spine)
Source: Joint Bone Spine - March 28, 2019 Category: Orthopaedics Source Type: research

Polymyalgia Rheumatica occurrence undermultikinase inhibitors (sorafenib and erlotinib) treatment
Publication date: Available online 27 March 2019Source: Joint Bone SpineAuthor(s): Frank Verhoeven, Delphine Weil-Verhoeven, Clément Prati, Vincent Di Martino, Daniel Wendling (Source: Joint Bone Spine)
Source: Joint Bone Spine - March 28, 2019 Category: Orthopaedics Source Type: research

Isolated Muscle Hypertrophy Revealing Diffuse Large B-Cell Lymphoma
Publication date: Available online 27 March 2019Source: Joint Bone SpineAuthor(s): Julie Merindol, Anne Calleja, Madleen Chassang, Nihal Martis (Source: Joint Bone Spine)
Source: Joint Bone Spine - March 28, 2019 Category: Orthopaedics Source Type: research

Associations of hyperuricemia, gout, and UA-lowering therapy with the risk of fractures: a meta-analysis of observational studies
Publication date: Available online 22 March 2019Source: Joint Bone SpineAuthor(s): Qunchuan Zong, Yibo Hu, Qifu Zhang, Xiuxiu Zhang, Jingwen Huang, Tao WangAbstractObjective:A systematic review and meta-analysis were conducted to investigate the associations of hyperuricemia, gout, and uric acid (UA)-lowering therapy with the risk of fractures.Methods:Electronic searches on PubMed, the Cochrane Library, and Embase were conducted from inception to January 2, 2019. Observational studies assessing the effects of hyperuricemia, gout, and UA-lowering therapy on fractures were included in the meta-analysis. Summary risk estimate...
Source: Joint Bone Spine - March 23, 2019 Category: Orthopaedics Source Type: research

Knee replacement incidence and social deprivation: results from a French ecological study
Publication date: Available online 22 March 2019Source: Joint Bone SpineAuthor(s): Murielle Michel, Joséphine Bryère, Milka Maravic, Christian MarcelliAbstractObjectives:Temporal and geographic variations in knee osteoarthritis (OA) incidence occur worldwide. Regional variations also exist for socioeconomic status. We analyzed the association between socioeconomic deprivation (SED) and knee replacement (KR) incidence and assessed the proportion of KR associated with affluence.Methods:Patients aged 15 years and over hospitalized for KR in 2013 were included. We linked each patient to a municipality of residenc...
Source: Joint Bone Spine - March 23, 2019 Category: Orthopaedics Source Type: research

Destructive arthropathy of the shoulder complicating a cervical ependymoma
Publication date: Available online 16 March 2019Source: Joint Bone SpineAuthor(s): Zeineb Alaya (Source: Joint Bone Spine)
Source: Joint Bone Spine - March 16, 2019 Category: Orthopaedics Source Type: research

Epidural Corticosteroid Injections: Still Credible?
Publication date: Available online 9 March 2019Source: Joint Bone SpineAuthor(s): Hervé Bard, Marc Marty, Sylvie Rozenberg, Jean-Denis Laredo (Source: Joint Bone Spine)
Source: Joint Bone Spine - March 9, 2019 Category: Orthopaedics Source Type: research

Corneal and scleral involvement in inflammatory rheumatic disease: Rheumatologists and ophthalmologists exchanging views
Publication date: Available online 1 February 2019Source: Joint Bone SpineAuthor(s): Gaëlle Clavel, Eric Gabison, Luca SemeranoAbstractCorneal and scleral disorders related to inflammatory rheumatic diseases vary both in frequency and in severity. Sicca syndrome and its complications are the most common ocular manifestations and, together with episcleritis, can usually be managed by topical treatments. In contrast, the various forms of scleritis and peripheral ulcerative keratitis generally require systemic glucocorticoid therapy and the initiation or intensification of immunosuppressive treatment. Corneal and scleral...
Source: Joint Bone Spine - March 8, 2019 Category: Orthopaedics Source Type: research

The risk of Sjogren's syndrome in the older adults with gout: A medicare claims study
ConclusionsGout was associated with more than 1.7-fold higher risk of incident SS in adults 65 years or older. This finding needs to be reproduced and the underlying mechanisms for this association need further study. (Source: Joint Bone Spine)
Source: Joint Bone Spine - March 8, 2019 Category: Orthopaedics Source Type: research

Assessment of major salivary gland size in primary Sjögren's syndrome: Comparison between clinical examination and ultrasonography
ConclusionClinical measurement of parotidomegaly was concordant between two observers on a binary mode (presence/absence). However, concordance on direct measurement was weak. US could be a complementary examination. (Source: Joint Bone Spine)
Source: Joint Bone Spine - March 8, 2019 Category: Orthopaedics Source Type: research

Editorial Board
Publication date: March 2019Source: Joint Bone Spine, Volume 86, Issue 2Author(s): (Source: Joint Bone Spine)
Source: Joint Bone Spine - March 4, 2019 Category: Orthopaedics Source Type: research

Contents
Publication date: March 2019Source: Joint Bone Spine, Volume 86, Issue 2Author(s): (Source: Joint Bone Spine)
Source: Joint Bone Spine - March 4, 2019 Category: Orthopaedics Source Type: research

Pathogenic effects of anti-citrullinated protein antibodies in rheumatoid arthritis – role for glycosylation
Publication date: Available online 25 January 2019Source: Joint Bone SpineAuthor(s): Frédéric CoutantAbstractThe identification in 1998 of the main antigenic substrate recognized by autoantibodies was a dramatic turning point in our understanding of rheumatoid arthritis (RA) biology. Now, two decades later, antibodies to citrullinated proteins are viewed no longer as mere biomarkers for RA, but also as major pathophysiological factors involved in the development of bone loss and joint pain. These pathogenic effects are ascribable to abnormal autoantibody glycosylation via a pathway involving the Th17T cells. ...
Source: Joint Bone Spine - February 28, 2019 Category: Orthopaedics Source Type: research

Knee psoriatic enthesitis assessed using positron emission tomography (PET) – FNa merged to ultrahigh field magnetic resonance imaging (UHF-MRI)
Publication date: Available online 17 January 2019Source: Joint Bone SpineAuthor(s): Serge Cammilleri, Sophie Gabriel, Arnaud Le Troter, Christophe Chagnaud, Jean Pierre Mattei, David Bendahan, Sandrine Guis (Source: Joint Bone Spine)
Source: Joint Bone Spine - February 27, 2019 Category: Orthopaedics Source Type: research

The effect of periodontal treatment on patients with rheumatoid arthritis: the ESPERA randomised controlled trial
Conclusions: Although no clinical effect of periodontal treatment on RA was identified, this trial provides important data to support periodontal care in RA patients. Periodontal treatment is safe and reduces oral inflammation with a possible effect on oral health QoL. Since both periodontitis and RA are complex and multifactorial chronic diseases, it is likely that patient-centred approaches involving both oral health professionals and rheumatologists will contribute to optimal patient care. ISRCTN79186420. (Source: Joint Bone Spine)
Source: Joint Bone Spine - February 27, 2019 Category: Orthopaedics Source Type: research

Motivational Interviewing to Improve Treatment Adherence
Publication date: Available online 22 February 2019Source: Joint Bone SpineAuthor(s): Catherine Beauvais (Source: Joint Bone Spine)
Source: Joint Bone Spine - February 23, 2019 Category: Orthopaedics Source Type: research

Ultrasound and clinical features of hip involvement in patients with gout
Conclusion: Our results indicate that detecting monosodium urate crystals by ultrasound is common at hip joint in patients with gout. (Source: Joint Bone Spine)
Source: Joint Bone Spine - February 17, 2019 Category: Orthopaedics Source Type: research

Complex regional pain syndrome secondary to everolimus: two cases
Publication date: Available online 15 February 2019Source: Joint Bone SpineAuthor(s): Marion Magnol, Yannick Degboé, Guillaume Couture, Arnaud Constantin, Michel Laroche (Source: Joint Bone Spine)
Source: Joint Bone Spine - February 16, 2019 Category: Orthopaedics Source Type: research

Geoepidemiology of Sjögren's syndrome in Latin America
Conclusions: The clinical spectrum of SS differs between countries and continents. Genetic differences relying upon ancestry could explain these findings. However, environmental factors have proven to be important determinants in the development of autoimmune diseases (i.e., autoimmune ecology). Thus, ancestry and the autoimmune ecology should be considered in studies aimed to evaluate the geoepidemiology of SS and other autoimmune diseases. (Source: Joint Bone Spine)
Source: Joint Bone Spine - February 16, 2019 Category: Orthopaedics Source Type: research

Single Tumor-Like Tophus
Publication date: Available online 14 February 2019Source: Joint Bone SpineAuthor(s): Laurent Messer, Pierre Marie Duret, Auriane Mallick, Thibault Willaume, Lionel Spielmann, Emmanuel Chatelus (Source: Joint Bone Spine)
Source: Joint Bone Spine - February 15, 2019 Category: Orthopaedics Source Type: research

Reply to the comment of Sartorelli et al. “Diagnostic approach and novel therapeutic option for cardiac inflammatory disorders”
Publication date: Available online 11 February 2019Source: Joint Bone SpineAuthor(s): Loïc Meudec, Sébastien Ottaviani (Source: Joint Bone Spine)
Source: Joint Bone Spine - February 12, 2019 Category: Orthopaedics Source Type: research

Assessment of major salivary gland size in primary Sjögren’s syndrome: comparison between clinical examination and ultrasonography
Conclusion: Clinical measurement of parotidomegaly was concordant between two observers on a binary mode (presence/absence). However, concordance on direct measurement was weak. US could be a complementary examination. (Source: Joint Bone Spine)
Source: Joint Bone Spine - February 12, 2019 Category: Orthopaedics Source Type: research

The management of Osteogenesis Imperfecta in Adults: state of the art
Publication date: Available online 8 February 2019Source: Joint Bone SpineAuthor(s): Marie-Hélène Lafage-Proust, Isabelle CourtoisABSTRACTOsteogenesis imperfecta (OI) is a genetic disease whose clinical phenotype and severity vary considerably. The increased risk of fractures due to bone fragility persists in adulthood, notably after 40 years of age, albeit at a lower level than during growth. Adults with OI require periodic evaluations of the other manifestations of OI including hearing loss, respiratory impairments, ocular and dental abnormalities, and cardiovascular disease. Follow-up should therefore be p...
Source: Joint Bone Spine - February 9, 2019 Category: Orthopaedics Source Type: research

Diagnostic approach and novel therapeutic option for cardiac inflammatory disorders. Comment on “Antisynthetase syndrome and cardiac involvement: a rare association” by Meudec et al. Joint Bone Spine 2018. doi: 10.1016/j.jbspin.2018.09.019
Publication date: Available online 7 February 2019Source: Joint Bone SpineAuthor(s): Silvia Sartorelli, Corrado Campochiaro, Giacomo De Luca (Source: Joint Bone Spine)
Source: Joint Bone Spine - February 8, 2019 Category: Orthopaedics Source Type: research

Assessment of the adherence to disease-modifying drugs in patients with chronic inflammatory rheumatic diseases: results of a survey of 1594 patients
This study suggests that more than 20% of CIRDs patients are low adherent to their DMARDs, and this is more frequent when bDMARDs are administered as a monotherapy. (Source: Joint Bone Spine)
Source: Joint Bone Spine - February 7, 2019 Category: Orthopaedics Source Type: research

Exploratory study of adalimumab in twelve patients with chronic low back pain associated with Modic I changes
Publication date: Available online 7 February 2019Source: Joint Bone SpineAuthor(s): Stéphane Genevay, Sana Boudabbous, Federico Balagué (Source: Joint Bone Spine)
Source: Joint Bone Spine - February 7, 2019 Category: Orthopaedics Source Type: research

The Risk of Sjogren’s Syndrome in the Older adults with Gout: A Medicare Claims Study
Conclusions: Gout was associated with more than 1.7-fold higher risk of incident SS in adults 65 years or older. This finding needs to be reproduced and the underlying mechanisms for this association need further study. (Source: Joint Bone Spine)
Source: Joint Bone Spine - February 7, 2019 Category: Orthopaedics Source Type: research

Curative Treatment of Prosthetic Joint Infection in Patients Younger than 80 vs. 80 or Older
Publication date: Available online 6 February 2019Source: Joint Bone SpineAuthor(s): Chloé Jamakorzyan, Vanina Meyssonnier, Younes Kerroumi, Benoit Villain, Beate Heym, Luc Lhotellier, Valérie Zeller, Jean-Marc Ziza, Simon MarmorResumeObjective: Prosthetic joint infection (PJI) is a serious complication of joint replacement surgery. The major pharmacological and surgical treatments required by PJI increase the risk of peri-operative complications in elderly patients. The increase in life expectancy combined with procedural advances make these treatments possible even in the oldest patients. Here, our objectiv...
Source: Joint Bone Spine - February 7, 2019 Category: Orthopaedics Source Type: research

Increased incidence of spondyloarthropathies in patients with Takayasu arteritis: a systematic clinical survey
Conclusion:Our results suggest a significant association between Takayasu arteritis and spondyloarthropathy. Possible shared genetic or immunopathogenic processes may explain this association which merits further investigations. (Source: Joint Bone Spine)
Source: Joint Bone Spine - February 7, 2019 Category: Orthopaedics Source Type: research

Bortezomib Improved the Joint Manifestations of Rheumatoid Arthritis in Three Patients
We report on 3 patients with rheumatoid arthritis and multiple myeloma in whom bortezomib therapy was associated with improvements in the joint manifestations. The contribution to this effect of the concomitant glucocorticoid therapy is discussed. (Source: Joint Bone Spine)
Source: Joint Bone Spine - February 7, 2019 Category: Orthopaedics Source Type: research

Statins, myalgia, and rhabdomyolysis
Publication date: Available online 6 February 2019Source: Joint Bone SpineAuthor(s): Anne TournadreAbstractStatin-associated muscle symptoms (SAMSs) vary considerably in frequency and severity, with a spectrum extending from myalgia with normal creatine kinase (CK) levels or asymptomatic hyperCKemia to potentially life-threatening rhabdomyolysis and necrotizing autoimmune myopathy. Myalgia with CK elevation is the most common presentation. Onset is usually within 1 month after statin initiation or dosage intensification, and the symptoms can be expected to resolve within a few weeks after treatment discontinuation. The mec...
Source: Joint Bone Spine - February 7, 2019 Category: Orthopaedics Source Type: research