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How Alcohol Use Affects Health
You may have heard of Dry January, a campaign run in the U.K. by Alcohol Concern. To promote alcohol awareness, it involves (as you’ve likely gathered) completely abstaining from alcohol for the month of January. It’s a valuable campaign with noble intentions, but a minority of participants may unfortunately miss the wider point. A month of strict abstinence does lead some to drink more than they should come February 1. Remaining alcohol free for a month is an achievement which deserves to be rewarded, but compensatory drinking is not what Dry January is trying to advocate. A healthy attitude towards consumption (not ...
Source: Psych Central - February 13, 2016 Category: Psychiatry Authors: Dr. Wayne Osborne Tags: Addictions Alcoholism General Healthy Living Substance Abuse Abstinence Alcohol Abuse Alcoholic beverage Binge Drinking Drinking culture Liver disease Liver health Long-term effects of alcohol Moderation National Council on Alc Source Type: news

You Don't Need To Lose A Lot Of Weight To Start Seeing Health Benefits
This study clarifies conventional wisdom among obesity experts, who have traditionally advised patients to lose 5 to 10 percent of their body weight in order to improve blood pressure, cholesterol and blood sugar levels. But as anyone who has ever tried to lose weight can attest, there is a big difference between 5 percent and 10 percent.   "That’s a very vague, wide range," Klein said. "It’s much harder to achieve a 10 percent weight loss than it is to achieve a five percent weight loss." Klein said his study shows that even just a little bit of weight loss is enough to improve health, and that peopl...
Source: Science - The Huffington Post - February 23, 2016 Category: Science Source Type: news

Optimizing Acute Pain Management in the Obese Patient: Treatment and Monitoring Considerations
THE CHALLENGES OF PROVIDING SAFE AND EFFECTIVE pain management for patients with obesity are present throughout the perioperative setting. Obesity is associated with chronic medical comorbidities, such as coronary artery disease, stroke, chronic kidney disease, nonalcoholic fatty liver disease, and type 2 diabetes.1 Other obesity-associated comorbidities include breast, endometrial, ovarian, colorectal, esophageal, kidney, pancreatic, and prostate cancers, chronic back pain, and osteoarthritis.1 The demand for bariatric surgery has risen markedly in recent years with the total number of surgeries performed in the United St...
Source: Journal of PeriAnesthesia Nursing - February 27, 2016 Category: Nursing Authors: Maureen F. Cooney Tags: Pain Care Source Type: research

Visceral Fat Triggers Heart Disease
I tell my patients to avoid drinking soda not just because they make you fat. Each sip of soda affects your health. Soda puts you at risk for health problems like metabolic syndrome. This is a collection of symptoms that can lead to diabetes, heart disease and other chronic diseases, like cancer. Soft drinks are the beverage of choice for millions of Americans. The latest research now reveals that sodas are a major cause of visceral fat — the deadliest kind of fat you can have, inflaming your tissues, rotting your blood vessels and upsetting your body chemistry. In a minute I’m going to tell you about a great healthy ...
Source: Al Sears, MD Natural Remedies - February 29, 2016 Category: Complementary Medicine Authors: Al Sears Tags: Heart Health heart disease metabolic syndrome Visceral Fat Source Type: news

Cardiac manifestations in alcoholic liver disease
Alcoholic liver disease is the most prevalent cause of progressive liver disease in Europe. Alcoholic cirrhosis occurs in 8%–20% of cases of alcoholic liver disease. It has significant influence on cardiovascular system and haemodynamics through increased heart rate, cardiac output, decreased systemic vascular resistance, arterial pressure and plasma volume expansion. Cirrhotic cardiomyopathy is characterised by systolic and diastolic dysfunction and electrophysiological abnormalities, if no other underlying cardiac disease is present. It is often unmasked only during pharmacological or physiological stress, when com...
Source: Postgraduate Medical Journal - March 21, 2016 Category: Journals (General) Authors: Milic, S., Lulic, D., Stimac, D., Ruzic, A., Zaputovic, L. Tags: Reviews Source Type: research

Chitotriosidase: A New Inflammatory Marker in Diabetic Complications
Chitotriosidase (CHIT1) belongs to chitinase family. So far this enzyme has been the best investigated human chitinase regarding its biological activity and association with various disorders. In a healthy population, CHIT1 activity is very low and originates in the circulating polymorphonuclear cells. Conversely, during the development of acute/chronic inflammatory disorders, the enzymatic activity of CHIT1 increases significantly. Recently, CHIT1 has also been involved in the pathogenesis of diabetes mellitus (DM). Mounting evidence from experimental studies revealing the increase of CHIT1 levels in pathological conditio...
Source: Pathobiology - April 26, 2016 Category: Pathology Source Type: research

Hepatitis C virus and neurological damage.
Authors: Mathew S, Faheem M, Ibrahim SM, Iqbal W, Rauff B, Fatima K, Qadri I Abstract Chronic hepatitis C virus (HCV) infection exhibits a wide range of extrahepatic complications, affecting various organs in the human body. Numerous HCV patients suffer neurological manifestations, ranging from cognitive impairment to peripheral neuropathy. Overexpression of the host immune response leads to the production of immune complexes, cryoglobulins, as well as autoantibodies, which is a major pathogenic mechanism responsible for nervous system dysfunction. Alternatively circulating inflammatory cytokines and chemokines and...
Source: World Journal of Hepatology - May 4, 2016 Category: Gastroenterology Tags: World J Hepatol Source Type: research

Are broken bones, loneliness and poor sleep really hidden killers?
Conclusion As the researchers say, the WHO definition of health encompasses physical, mental and social wellbeing – not just the presence or absence of disease. But how often are these extra dimensions taken into account when assessing a person's health status? In this sample of older adults, just looking at their disease status puts the majority of them into an apparently "robust" health group. Yet when you consider the additional dimensions of psychological health and wellbeing, you seem to get a much better indication of those who were at higher or lower risk of dying or being incapacitated in the coming...
Source: NHS News Feed - May 18, 2016 Category: Consumer Health News Tags: Lifestyle/exercise Medical practice Source Type: news

Dyspnoea as a predictor of cause-specific heart/lung disease mortality in Bangladesh: a prospective cohort study
Conclusions Dyspnoea, ascertained by a single question with binary response, predicts heart and lung disease mortality. Individuals reporting dyspnoea were twofold to ninefold more likely to die of diseases that involve the heart and/or lungs relative to the non-dyspnoeic individuals. Therefore, in those with chronic dyspnoea, workup to look for the five common dyspnoeic diseases resulting in increased mortality (COPD, asthma, heart disease, tuberculosis and lung cancer), all treatable, should reduce mortality and improve the public health.
Source: Journal of Epidemiology and Community Health - June 9, 2016 Category: Epidemiology Authors: Pesola, G. R., Argos, M., Chinchilli, V. M., Chen, Y., Parvez, F., Islam, T., Ahmed, A., Hasan, R., Rakibuz-Zaman, M., Ahsan, H. Tags: Epidemiologic studies, Cohort studies, Mortality and morbidity Other topics Source Type: research

Transplants give Garden Plain man a second chance at life
Chris Simon’s bucket list wasn’t anything fancy. He simply wanted to be able to ride a bike again. Or take a swim. Or go camping with friends. “Stuff I used to do all the time,” Simon said. “And all of a sudden it was taken away.” Those once simple joys were stolen by cystic fibrosis, the same disease that claimed his younger sister Emily’s life in 2009. The Simon family on Sunday will join millions of others around the world in celebrating Easter, a day symbolizing new beginnings. The holiday will have special significance for Chris, 26, who has another chapter dawning in his life after a double-lung/liver t...
Source: Cystic Fibrosis Worldwide Blog - April 20, 2014 Category: Respiratory Medicine Authors: Webmaster Tags: Uncategorized Source Type: blogs

A conceptual and practical approach to haemostasis in paediatric liver disease
Conclusion: we propose a model regarding haemostasis in paediatric liver disease, taking into account a number of specific variables and mechanisms, as well as the type of liver disease, which will provide a framework for clinical decision-making in these complex patients.
Source: Archives of Disease in Childhood - August 16, 2016 Category: Pediatrics Authors: Magnusson, M., Ignjatovic, V., Hardikar, W., Monagle, P. Tags: Liver disease, Drugs: cardiovascular system, Stroke Review Source Type: research

Special Interest Groups - Updates in Psychosomatics (SIG-UPs): Alcohol Use Disorders in Women
While low to moderate alcohol use has shown to yield cardiovascular benefit, heavy alcohol intake has been associated with many adverse effects including increased risk of hemorrhagic stroke, alcoholic liver disease, pancreatitis, as well as overall morbidity and mortality. Recent studies show a clear gender difference; women have an increased risk for all-cause mortality with moderate to heavy alcohol use.1 Worldwide statistics indicate 45% of women consume alcohol,1 stressing the need for careful screening and dual diagnosis treatment to decrease use and improve overall health outcomes.
Source: Psychosomatics - August 20, 2016 Category: Psychiatry & Psychology Authors: Neeta Shenai, Jody Glance, Patrick Marshalek Source Type: research

Added Sugars and Cardiovascular Disease Risk in Children: A Scientific Statement From the American Heart Association.
CONCLUSIONS: Associations between added sugars and increased cardiovascular disease risk factors among US children are present at levels far below current consumption levels. Strong evidence supports the association of added sugars with increased cardiovascular disease risk in children through increased energy intake, increased adiposity, and dyslipidemia. The committee found that it is reasonable to recommend that children consume ≤25 g (100 cal or ≈6 teaspoons) of added sugars per day and to avoid added sugars for children <2 years of age. Although added sugars most likely can be safely consumed in low amounts as ...
Source: Circulation - August 21, 2016 Category: Cardiology Authors: Vos MB, Kaar JL, Welsh JA, Van Horn LV, Feig DI, Anderson CA, Patel MJ, Cruz Munos J, Krebs NF, Xanthakos SA, Johnson RK, American Heart Association Nutrition Committee of the Council on Lifestyle and Cardiometabolic Health; Council on Clinical Cardiology Tags: Circulation Source Type: research

Clinical outcome prediction in aneurysmal subarachnoid hemorrhage - Alterations in brain-body interface.
CONCLUSIONS: Using the aforementioned results generated from binary logistic regression models, we can identify potential patients who are in the high risk group of neurological deterioration. Specific therapies can be tailored to prevent these detriments, including treatment of hypertension, seizures, early detection and treatment of myocardial infarction, and prevention of hepatic encephalopathy. PMID: 27583179 [PubMed]
Source: Surgical Neurology International - September 2, 2016 Category: Neurosurgery Tags: Surg Neurol Int Source Type: research

The Role of the Model of End-Stage Liver Disease Score in Predicting Outcomes of Carotid Endarterectomy
Conclusion: High MELD score places asymptomatic patients undergoing carotid endarterectomy at a higher risk of adverse outcomes in the 30 days following surgery. This provides further empirical evidence for risk stratification when considering treatment for these patients. Outcomes of medical management or carotid stenting should be investigated in high-risk patients.
Source: Vascular and Endovascular Surgery - September 13, 2016 Category: Surgery Authors: Krafcik, B. M., Farber, A., Eslami, M. H., Kalish, J. A., Rybin, D., Doros, G., King, E. G., Siracuse, J. J. Tags: Original Manuscripts Source Type: research