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Condition: Liver Disease

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Total 688 results found since Jan 2013.

Elevated Aminotransferase Levels and Intracerebral Hemorrhage Deaths in a General Japanese Population
Int Heart J. 2023;64(4):678-683. doi: 10.1536/ihj.23-027.ABSTRACTAlthough chronic liver disease has been associated with cardiovascular disease, to which metabolic syndrome might be related, intracerebral hemorrhage (ICH) generally has not been focused. Associations of chronic liver disease assessed by aspartate (AST) and alanine (ALT) aminotransferase levels with ICH deaths were examined using 15,952 subjects without a history of cardiovascular disease who underwent annual health checkups in 1997 in Japan. Proportional hazards regression analyses adjusted for age, sex, hypertension, current smoking, diabetes mellitus, dri...
Source: International Heart Journal - July 30, 2023 Category: Cardiology Authors: Hisako Tsuji Ichiro Shiojima Source Type: research

Clopidogrel, Aspirin and Proton Pump Inhibition after Percutaneous Valve Implants: An Update.
Conclusions: TAVR is a new technology that compresses a tissue valve onto an expandable stent. Technical and procedural issues have been solved, but strokes and major bleeding still affect patients' life despite double antiplatelet therapy given to reduce MACCE. To balance pros and cons, antithrombotic therapy with Warfarin or new anticoagulants can be used in patients with previous AF or NOAF to prevent stroke; while single antiplatelet with PPI is a better alternative in patients with liver disease, gastric ulcer or drug abuse to avoid bleeding events. While waiting for randomized trials, a tailored therapy based upon ph...
Source: Current Pharmaceutical Design - December 4, 2012 Category: Drugs & Pharmacology Authors: Fusari M Tags: Curr Pharm Des Source Type: research

Albumin: Pathophysiologic basis of its role in the treatment of cirrhosis and its complications
Abstract Since the introduction of human serum albumin as a plasma expander in the 1940s, considerable research has allowed a better understanding of its biochemical properties and potential clinical benefits. Albumin has a complex structure, which is responsible for a variety of biological functions. In disease, albumin molecule is susceptible to modifications that may alter its biological activity. During the last decades, different methods to measure albumin function have been developed. Recent studies have shown that not only albumin concentration but also albumin function is reduced in liver failure. This observation ...
Source: Hepatology - February 19, 2013 Category: Internal Medicine Authors: Rita Garcia‐Martinez, Paolo Caraceni, Mauro Bernardi, Pere Gines, Vicente Arroyo, Rajiv Jalan Tags: Liver Failure, Cirrhosis and Portal Hypertension Source Type: research

How to use... lupus anticoagulants
Introduction Lupus anticoagulants (LA) were first detected in patients with systemic lupus erythematosus (SLE) in 1952 by Conley and Hartmann.1 They identified patients in whom the activated partial thromboplastin time (APTT) was prolonged and which did not correct on the addition of normal plasma. Although Conley and Hartmann's original description was in association with a haemorrhagic disorder, subsequent reports from the 1960s highlighted patients with thrombotic events in the presence of LA.2 The term ‘lupus anticoagulant’ was introduced by Feinstein and Rapaport in 1972.3 It has, however, caused some conf...
Source: Archives of Disease in Childhood - Education and Practice - March 14, 2013 Category: Pediatrics Authors: Sen, E. S., Beresford, M. W., Avcin, T., Ramanan, A. V. Tags: Liver disease, Immunology (including allergy), Hepatitis and other GI infections, Travel medicine, Epilepsy and seizures, Headache (including migraine), Stroke, Pregnancy, Reproductive medicine, Rheumatology Interpretations Source Type: research

Republished: Mainstreaming HIV services for men who have sex with men: the role of general practitioners
Mainstreaming HIV services for men who have sex with men: The role of general practitioners General practitioners (GPs) and other primary care doctors around the world have a strong potential for providing quality HIV prevention, testing and treatment for men who have sex with men, as advocated by the recent WHO guideline.1 As the HIV epidemic becomes more focused on chronic disease care in many parts of the world, a number of primary care issues come to the forefront of clinical HIV service delivery. GPs have advantages in providing HIV services because of their position as trusted, community-based, long-term advocates fo...
Source: Postgraduate Medical Journal - March 12, 2013 Category: Journals (General) Authors: Wong, W. C. W., Kidd, M. R., Tucker, J. D. Tags: Liver disease, Sexual transmitted infections (viral), General practice / family medicine, Immunology (including allergy), Drugs: infectious diseases, HIV/AIDS, Stroke, Hypertension, Communication, Ethics, Legal and forensic medicine Republished editoria Source Type: research

Diabetes is not an independent risk factor for hepatocellular carcinoma
ConclusionsDiabetes is not an independent risk factor for HCC after considering the effects of alcohol‐related diagnoses, chronic liver disease and potential detection bias. This article is protected by copyright. All rights reserved.
Source: Diabetes/Metabolism Research and Reviews - May 1, 2013 Category: Endocrinology Authors: Chin‐Hsiao Tseng Tags: Research Article Source Type: research

Adipose tissue dysfunction contributes to obesity related metabolic diseases
Obesity significantly increases the risk of developing type 2 diabetes, hypertension, coronary heart disease, stroke, fatty liver disease, dementia, obstructive sleep apnea and several types of cancer. Adipocyte and adipose tissue dysfunction represent primary defects in obesity and may link obesity to metabolic and cardiovascular diseases. Adipose tissue (AT) dysfunction manifests by a proinflammatory adipokine secretion pattern that mediate auto/paracrine and endocrine communication and by inflammatory cell infiltration, particularly in intra-abdominal fat. Impaired AT function is caused by the interaction of genetic, be...
Source: Best Practice and Research. Clinical Endocrinology and Metabolism - April 1, 2013 Category: Endocrinology Authors: Matthias Blüher Tags: Section 2: Health Impacts of Obesity Source Type: research

'Early death map' shows English health inequality
“North and South health divide: Chilling study reveals premature death is 'postcode lottery',” the Daily Mirror reports. The news is based on a new interactive map showing the variation in premature death rates across England. The Longer Lives map, created by the new organisation Public Health England, ranks 150 local authorities by their premature death rates (deaths occurring before age 75). The interactive map also enables users to compare these areas by five common causes of premature (and potentially preventable) deaths: cancer heart disease stroke lung diseases, such as chronic obstructive pulmonary ...
Source: NHS News Feed - June 11, 2013 Category: Consumer Health News Tags: Lifestyle/exercise Heart/lungs Cancer QA articles Source Type: news

Pneumatosis cystoides intestinalis: Modern diagnostic modalities
We read with interest the article by Masuda et al. on the use of computed tomographic (CT) colonoscopy for the diagnosis of pneumatosis cystoides intestinalis. We would like to share our experience of a similar case. A 73-year-old woman with history of hypertension and ischemic stroke was referred for evaluation of chronic constipation and abdominal distention. Taking into account the patient's desire for a non-invasive exploration, a CT colonoscopy was initially performed; CT disclosed multiple air-containing cysts within the wall of the sigmoid colon, suggesting the diagnosis of idiopathic pneumatosis cystoides intestina...
Source: Digestive and Liver Disease - March 11, 2013 Category: Gastroenterology Authors: Georgios Mavrogenis, Xavier Chapeaux, Véronique Benali, Philippe Warzée Tags: Correspondence Source Type: research

Systematic bias in surgeons' predictions of the donor‐specific risk of liver transplant graft failure
In conclusion, transplant surgeons vary widely in their predictions of the donor‐specific risk of graft failure, and they demonstrate a systematic bias toward inaccurately low estimates of graft failure, particularly for higher risk organs. Liver Transpl, 2013. © 2013 AASLD.
Source: Liver Transplantation - June 19, 2013 Category: Transplant Surgery Authors: Michael L. Volk, Meghan Roney, Robert M. Merion Tags: Original Article Source Type: research

157 E-Books New to JEFFLINE
Scott Library added these 157 e-books to the growing collection in May and June: Accurate Results in the Clinical Laboratory Adult Emergency Medicine Adult-Gerontology and Family Nurse Practitioner Certification Examination (4th ed.) Advanced Assessment: Interpreting Findings and Formulating Differential Diagnoses (2nd ed.) Advancing Your Career: Concepts of Professional Nursing (5th ed.) Arrhythmia Essentials Atlas of Advanced Operative Surgery Atlas of Clinical Neurology (3rd ed.) Atlas of Hematopathology: Morphology, Immunophenotype, Cytogenetics, and Molecular Approaches Atlas of Human Infectious Diseases Atlas of No...
Source: What's New on JEFFLINE - June 25, 2013 Category: Databases & Libraries Authors: Gary Kaplan Tags: All News Clinicians Researchers Students Teaching Faculty Source Type: news

Reduced thoracic fluid content in early stage primary biliary cirrhosis that associates with impaired cardiac inotropy.
Conclusion: This study has confirmed that TFC is reduced in those with PBC, that this is specific to PBC and that it associates independently with markers of cardiac inotropy. PMID: 23868409 [PubMed - as supplied by publisher]
Source: Am J Physiol Gastroi... - July 18, 2013 Category: Gastroenterology Authors: Zalewski P, Jones DE, Lewis I, Frith J, Newton JL Tags: Am J Physiol Gastrointest Liver Physiol Source Type: research