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Condition: Liver Disease

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Total 688 results found since Jan 2013.

Teen drinking linked to raised breast cancer risk
Conclusion Alcohol consumption is already recognised as a risk factor for breast cancer. And this large, well-conducted study seems to confirm that young women between their first period and first pregnancy are particularly susceptible.  One limitation of the study is that the women were asked to recall their drinking habits when they were far younger, which could mean the results are less reliable. Also, other factors called confounders might have affected women’s risk of breast cancer, although researchers did adjust their findings for a range of other risk factors. As the authors point out, it is crucial that youn...
Source: NHS News Feed - August 29, 2013 Category: Consumer Health News Tags: Cancer Lifestyle/exercise Source Type: news

As preschool obesity rates dip, Boston Children’s expert suggests feds step to the plate
The scales may not be tipping quite so precipitously for some low-income preschoolers. So says a new report from the Centers for Disease Control and Prevention (CDC). Nineteen states saw small decreases in obesity rates among preschoolers between 2008 and 2011, while rates held steady in another 20 states. Is this cause for celebration, cautious optimism or concern? Perhaps all of the above, says David Ludwig, MD, PhD, director of the New Balance Foundation Obesity Prevention Center Boston Children’s Hospital. “The report is a small, but encouraging, sign after nearly half a century of bad news.” The latest data...
Source: Thrive, Children's Hospital Boston - September 11, 2013 Category: Pediatrics Authors: Lisa Fratt Tags: All posts Childhood obesity Children's in the news Health & wellness Healthful eating Research David Ludwig New Balance Foundation Obesity Prevention Center Source Type: news

Antithrombotic Medication Use and Bleeding Risk in Medically Ill Patients After Hospitalization
Conclusions: Careful consideration of these demonstrated bleed-associated comorbidities before initiating anticoagulation or combining antithrombotic medications in medically ill patients may improve strategies for prevention of postdischarge thromboembolism.
Source: Clinical and Applied Thrombosis/Hemostasis - September 15, 2013 Category: Hematology Authors: Mahan, C. E., Spyropoulos, A. C., Fisher, M. D., Fields, L. E., Mills, R. M., Stephenson, J. J., Fu, A.-C., Klaskala, W. Tags: Original Articles Source Type: research

The Role of Statins in the Treatment of Type 2 Diabetes Mellitus: an Update.
Abstract The prevalence of type 2 diabetes mellitus (T2DM) is increasing worldwide. T2DM is associated with both microvascular (neuropathy, nephropathy and retinopathy) and macrovascular complications [coronary artery disease (CAD), stroke, carotid artery disease and peripheral artery disease (PAD)]. Apart from acting on diabetic dyslipidemia, statins were shown to exert beneficial effects on several diabetic complications as well as other cardiovascular (CVD) risk predictors such as endothelial dysfunction, inflammation, oxidative stress, chronic kidney disease (CKD), non-alcoholic fatty liver disease (NAFLD), me...
Source: Current Pharmaceutical Design - September 12, 2013 Category: Drugs & Pharmacology Authors: Niki Katsiki, Vasilios G Athyros, Asterios Karagiannis, Dimitri P Mikhailidis Tags: Curr Pharm Des Source Type: research

Risk Factors for Aspiration in Community-acquired Pneumonia: Analysis of a Hospitalized UK Cohort
Abstract: Background: There is a move toward finding clinically useful “phenotypes” in community-acquired pneumonia: groups of patients displaying distinct clinical characteristics, microbiology, and prognosis. Aspiration pneumonia is an intuitive clinical phenotype; however, to date there are no recognized diagnostic criteria, and data regarding outcomes in suspected aspiration are limited.Methods: An observational study of 1348 patients hospitalized with community-acquired pneumonia in the United Kingdom examined both short- and long-term outcomes for patients at risk of aspiration pneumonia. Patients were defined as...
Source: The American Journal of Medicine - September 19, 2013 Category: Journals (General) Authors: Joanne K. Taylor, Gillian B. Fleming, Aran Singanayagam, Adam T. Hill, James D. Chalmers Tags: Clinical research studies Source Type: research

Modest cancer prevention benefit with long-term multivitamin supplementation: Physicians' Health Study II results warrant cautious interpretation
Commentary on Gaziano JM, Sesso HD, Christen WG, et al.. Multivitamins in the prevention of cancer in men: the Physicians’ Health Study II randomised controlled trial. JAMA 2012;308:1871–80. Context Various vitamins and minerals have been shown to inhibit carcinogenesis or reduce cancer risk in preclinical experiments and observational studies. Such work has given rise to several chemoprevention trials of isolated nutrients, many of which (eg, Alpha-Tocopherol and Beta-Carotene (ATBC) Trial, Carotene and Retinol Efficacy Trial (CARET) and Selenium and Vitamin E Cancer Prevention Trial (SELECT)) have produced d...
Source: Evidence-Based Medicine - November 21, 2013 Category: Internal Medicine Authors: Demark-Wahnefried, W. Tags: Liver disease, Clinical trials (epidemiology), Epidemiologic studies, Drugs: cardiovascular system, Stroke, Diet, Prevention, Complementary medicine, Dermatology, Prostate Therapeutics Source Type: research

Antivirals for HCV improve kidney and cardiovascular diseases in diabetic patients
(Wiley) Researchers from Taiwan reveal that antiviral therapy for hepatitis C virus (HCV) improves kidney and cardiovascular outcomes for patients with diabetes. Results of the study published in Hepatology, a journal of the American Association for the Study of Liver Diseases, show that incidences of kidney disease, stroke, and heart attack were lower in patients treated with pegylated interferon and ribavirin compared to HCV patients not treated with antivirals or diabetic patients not infected with the virus.
Source: EurekAlert! - Infectious and Emerging Diseases - December 11, 2013 Category: Infectious Diseases Source Type: news

Analysis of disability using WHODAS 2.0 among the middle-aged and elderly in Cinco Villas, Spain
Conclusions: For the first time, this study furnishes detailed disability prevalence figures and data on associated variables in a middle-aged and elderly Western population.
Source: Disability and Health Journal - September 27, 2013 Category: Disability Authors: J. Almazán-Isla, M. Comín-Comín, J. Damián, E. Alcalde-Cabero, C. Ruiz, E. Franco, G. Martín, L.A. Larrosa-Montañés, J. de Pedro-Cuesta, DISCAP-ARAGON Research Group Tags: Research Papers Source Type: research

Adiponectin as a routine clinical biomarker.
Abstract Adiponectin is a protein synthesized and secreted predominantly by adipocytes into the peripheral blood. However, circulating adiponectin level is inversely related with body weight, especially visceral fat accumulation. The mechanism of this paradoxical relation remains obscure. Low circulating adiponectin concentrations (hypoadiponectinemia; <4 μg/mL) are associated with a variety of diseases, including dysmetabolism (type 2 diabetes, insulin resistance, hypertension, dyslipidemia, metabolic syndrome, hyperuricemia), atherosclerosis (coronary artery disease, stroke, peripheral artery disease), slee...
Source: Clin Med Res - January 1, 2014 Category: Research Authors: Kishida K, Funahashi T, Shimomura I Tags: Best Pract Res Clin Endocrinol Metab Source Type: research

Wine and chocolate may not 'beat diabetes'
This study does not give the green light to drink red wine above the recommended levels or to consume chocolate often – any potential benefits of diabetes prevention are likely to be overshadowed by the already known risks of excessive sugar, fat and alcohol consumption, including liver disease, cardiovascular disease, stroke and cancer.   Links To The Headlines Chocolate And Red Wine 'Can Beat Diabetes'. Sky News, January 20 2014 Chocolate and red wine can help stave off diabetes: High levels of antioxidants can regulate blood glucose levels. Daily Mail, January 20 2014 Red wine 'protects against diabetes' - and cho...
Source: NHS News Feed - January 20, 2014 Category: Consumer Health News Tags: Diabetes Food/diet Source Type: news

The association between self-reported history of physical diseases and psychological distress in a community-dwelling Japanese population: the Ohsaki Cohort 2006 Study
Conclusions: Subjects with a history of physical disease were significantly and positively associated with psychological distress, and social support did not modify this association for most physical diseases. Even after patients have left hospital following treatment for physical disease, they require continuous monitoring for psychological distress by doctors and paramedics.
Source: The European Journal of Public Health - January 24, 2014 Category: Journals (General) Authors: Nakaya, N., Kogure, M., Saito-Nakaya, K., Tomata, Y., Sone, T., Kakizaki, M., Tsuji, I. Tags: Mental health Source Type: research

Reply Effects of Habitual Coffee Consumption on Vascular Function
We thank Dr. Siasos and colleagues for pointing out that habitual coffee consumption has been associated with improved endothelial function in elderly inhabitants of Ikaria Island (1). The improvement in endothelial function may in part account for the associations of moderate coffee intake (about 2 to 4 cups daily) with lower risks for coronary heart disease and stroke (2). Indeed, even in the setting of endothelium damage, coffee has the ability to prevent arterial thrombus formation, a benefit that is independent of its caffeine content (3). Recent studies also indicate that moderate daily coffee intake may confer pro...
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - February 10, 2014 Category: Cardiology Source Type: research

Reply: Effects of Habitual Coffee Consumption on Vascular Function
We thank Dr. Siasos and colleagues for pointing out that habitual coffee consumption has been associated with improved endothelial function in elderly inhabitants of Ikaria Island . The improvement in endothelial function may in part account for the associations of moderate coffee intake (about 2 to 4 cups daily) with lower risks for coronary heart disease and stroke . Indeed, even in the setting of endothelium damage, coffee has the ability to prevent arterial thrombus formation, a benefit that is independent of its caffeine content . Recent studies also indicate that moderate daily coffee intake may confer protection a...
Source: Journal of the American College of Cardiology - November 1, 2013 Category: Cardiology Authors: James J. DiNicolantonio, James H. O'Keefe, Carl J. Lavie Tags: Letters to the Editor Source Type: research

Prognostic models for stable coronary artery disease based on electronic health record cohort of 102 023 patients
Conclusion These validated prognostic models could be used in clinical practice to support risk stratification as recommended in clinical guidelines.
Source: European Heart Journal - April 1, 2014 Category: Cardiology Authors: Rapsomaniki, E., Shah, A., Perel, P., Denaxas, S., George, J., Nicholas, O., Udumyan, R., Feder, G. S., Hingorani, A. D., Timmis, A., Smeeth, L., Hemingway, H. Tags: Coronary artery disease Source Type: research

Quality of Life in Liver Transplant Patients with Neurologic Complications. (P4.031)
Conclusions: Our analysis shows that neurological complications worsen the quality of life of liver transplant patients. Especially regarding perception of health, ability to function independently due to physical and mental health limitations. Pain is a limiting condition in this group. Transplant patients who suffer neurological complications should be carefully followed up to reduce the impact on quality of life, in order to promote the ultimate goal of transplant.Disclosure: Dr. Gonzalez Toledo has nothing to disclose. Dr. Calle has received personal compensation for activities with UCB Pharma. Dr. Pagani Cassara has n...
Source: Neurology - April 9, 2014 Category: Neurology Authors: Gonzalez Toledo, M., Calle, A., Pagani Cassara, F., Tamargo, A., Thomson, A., Nadile, D., Gruz, F., Sinay, V. Tags: General Neurology III Source Type: research