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Condition: Liver Disease

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Total 688 results found since Jan 2013.

Evaluating the cause of death in obese individuals: a ten-year medical autopsy study.
Conclusion. Autopsies on obese individuals constitute a third of all adult medical autopsies in our center. Increased death rates in the obese due to pulmonary embolism and liver disease should receive special clinical attention. Autopsy findings in the obese population should contribute to overall premortem disease detection, prevention, and management. PMID: 25653872 [PubMed - in process]
Source: Journal of Obesity - February 6, 2015 Category: Eating Disorders and Weight Management Tags: J Obes Source Type: research

Erectile dysfunction and obstructive sleep apnea: From mechanisms to a distinct phenotype and combined therapeutic strategies
Non-communicable diseases (NCDs), mainly cardiovascular diseases, cancer, diabetes, and chronic respiratory diseases, are responsible for two-thirds of the 57 million annual deaths worldwide. Tobacco smoking, physical inactivity, unhealthy diets and the resulting obesity are established risk factors for many chronic diseases (Fig. 1). Management of the rise in the prevalence of chronic diseases is a major challenge facing governments and health-care systems worldwide. As these disorders are now the leading causes of death and hospitalizations, health authorities assign high priority to heart disease, diabetes, sleep apnea...
Source: Sleep Medicine Reviews - December 27, 2014 Category: Sleep Medicine Authors: Jean-Louis Pépin, Renaud Tamisier, Diane Godin-Ribuot, Patrick A. Lévy Tags: Guest editorial Source Type: research

Stroke after cyst fenestration in a patient with autosomal dominant polycystic kidney disease and polycystic liver disease: Not necessarily aneurysm-related
Publication date: Available online 26 February 2015 Source:Journal of the Formosan Medical Association Author(s): Chia-Ter Chao , John Huang , Tze-Wah Kao
Source: Journal of the Formosan Medical Association - February 27, 2015 Category: Journals (General) Source Type: research

Chronic hepatitis C virus infection and neurological and psychiatric disorders: An overview.
Abstract Hepatitis C virus (HCV) infection is considered a systemic disease because of involvement of other organs and tissues concomitantly with liver disease. Among the extrahepatic manifestations, neuropsychiatric disorders have been reported in up to 50% of chronic HCV infected patients. Both the central and peripheral nervous system may be involved with a wide variety of clinical manifestations. Main HCV-associated neurological conditions include cerebrovascular events, encephalopathy, myelitis, encephalomyelitis, and cognitive impairment, whereas "brain fog", depression, anxiety, and fatigue are at the top o...
Source: World Journal of Gastroenterology : WJG - February 28, 2015 Category: Gastroenterology Authors: Adinolfi LE, Nevola R, Lus G, Restivo L, Guerrera B, Romano C, Zampino R, Rinaldi L, Sellitto A, Giordano M, Marrone A Tags: World J Gastroenterol Source Type: research

Prevalence and risk factors of arthritis in a middle-aged and older Chinese population: the China Health and Retirement Longitudinal Study
Conclusion. Middle-aged and older Chinese adults had a high prevalence of arthritis. Cardiovascular disease is a novel risk factor for arthritis in this population.
Source: Rheumatology - March 24, 2015 Category: Rheumatology Authors: Li, C., Liu, T., Sun, W., Wu, L., Zou, Z.-Y. Tags: Rheumatoid Arthritis CLINICAL SCIENCE Source Type: research

FloTrac® Monitoring System: What Are Its Uses in Critically Ill Medical Patients?
Abstract: The FloTrac®/Vigileo device uses arterial pressure waveform analysis to calculate stroke volume and cardiac output; it does not require calibration against an independent measurement of cardiac output. Consequently, it provides a method to determine hemodynamic status, changes in the clinical course and responses to therapeutic interventions in patients who have arterial catheters in place. These devices perform relatively well in stable patients undergoing surgery and having an acceptable percentage error in differences between the FloTrac® device and invasive monitoring using pulmonary catheters. However, in ...
Source: The American Journal of the Medical Sciences - March 31, 2015 Category: Journals (General) Tags: Review Article Source Type: research

Treatment and survival of non-alcoholic steatohepatitis associated hepatocellular carcinoma
Background: The incidence of non-alcoholic steatohepatitis (NASH) is increasing worldwide and a poorly defined subset of patients develops end-stage liver disease and hepatocellular carcinoma (HCC). Differences in the biological behaviour, tumour characteristics, associated risk factors, treatment outcomes and overall survival of patients with NASH-HCC remain poorly defined. The aim of this study was to determine and analyze these differences in a large clinical cohort to guide treatment decisions. Methods: 1119 patients with HCC treated in an 11 year period at the University Medical Centre of the Johannes Gutenberg Unive...
Source: BMC Cancer - April 1, 2015 Category: Cancer & Oncology Authors: Arndt WeinmannYvonne AltSandra KochCarina NellesChristoph DüberHauke LangGerd OttoTim ZimmermannJens MarquardtPeter GalleMarcus WörnsJörn Schattenberg Source Type: research

Balancing risk and reward: a critical review of the intragastric balloon for weight loss
Worldwide, more than 1.4 billion adults are overweight or obese and either have or are at increased risk of numerous, potentially disabling conditions. In the United States, 68% of adults are overweight or obese, and the epidemic is spreading to children.1,2 Obesity is associated with a number of comorbidities including type 2 diabetes mellitus, coronary heart disease, sleep apnea, stroke, gallbladder and liver disease, musculoskeletal disease, and an increase in the prevalence of certain cancers.
Source: Gastrointestinal Endoscopy - April 14, 2015 Category: Gastroenterology Authors: Shantanu Gaur, Samuel Levy, Lisbeth Mathus-Vliegen, Ram Chuttani Tags: Review article Source Type: research

Middle age 'starts at 60' claims media
Conclusion This study is an interesting analysis of population data, which shows how looking at figures from a different perspective can change our view. We are used to hearing about "ageing Britain" and how the increasing numbers of older people could be a drain on the country's resources. This study considers whether our definitions of old age are too rigid and need to be revisited. In the paper, the researchers focus on results for Germany, but they have done calculations for 40 European countries, including the UK. This shows that the proportion of people in the UK aged 65 or over, given expected improvement...
Source: NHS News Feed - April 16, 2015 Category: Consumer Health News Tags: Lifestyle/exercise Obesity Source Type: news

Relationship between alcohol-attributable disease and socioeconomic status, and the role of alcohol consumption in this relationship: a systematic review and meta-analysis
Conclusions: Despite some limitations to our review, we have described relationships between socioeconomic status and a range of alcohol-attributable conditions, and explored the mediating and interacting effects of alcohol consumption where feasible. However, further research is needed to better characterise the relationship between SES, alcohol consumption and alcohol-attributable disease risk so as to gain a greater understanding of the mechanisms and pathways that influence the differential risk in harm between people of low and high socioeconomic status.
Source: BMC Public Health - April 18, 2015 Category: Consumer Health News Authors: Lisa JonesGeoff BatesEllie McCoyMark Bellis Source Type: research

Hypoglycemia in Emergency Department
Conclusions When hypoglycemic patients present in the emergency department, physicians should pay attention to the presence of infection, malignancy, liver diseases (liver cirrhosis and biliary tract infection), and acute renal failure.
Source: Journal of Acute Disease - April 22, 2015 Category: Emergency Medicine Source Type: research

UK life expectancy expected to rise to late 80s by 2030
Conclusion This analysis of population data provides some fascinating information about how life expectancy has changed over the past 30 years, and how it may change in the future. It found life expectancy for men and women will continue to rise. However, it also found the existing trends of the difference in life expectancy between different districts will continue to rise, which is of concern. Although the data shows more deprived areas have seen less of an improvement in life expectancy, the study cannot inform us what factors are responsible for the differences in life expectancy. There is one big limitation of any s...
Source: NHS News Feed - April 30, 2015 Category: Consumer Health News Tags: Lifestyle/exercise Medical practice Older people Source Type: news

Time trends for risk of severe age-related diseases in individuals with and without HIV infection in Denmark: a nationwide population-based cohort study
Publication date: Available online 27 May 2015 Source:The Lancet HIV Author(s): Line D Rasmussen , Margaret T May , Gitte Kronborg , Carsten S Larsen , Court Pedersen , Jan Gerstoft , Niels Obel Background Whether the reported high risk of age-related diseases in HIV-infected people is caused by biological ageing or HIV-associated risk factors such as chronic immune activation and low-grade inflammation is unknown. We assessed time trends in age-standardised and relative risks of nine serious age-related diseases in a nationwide cohort study of HIV-infected individuals and population controls. Methods We identified all ...
Source: The Lancet HIV - May 28, 2015 Category: Infectious Diseases Source Type: research

Subsequent mortality after hyperglycemic crisis episode in the non-elderly: a national population-based cohort study
Abstract Hyperglycemic crisis episodes (HCEs)—diabetic ketoacidosis and the hyperosmolar hyperglycemic state—are the most serious acute metabolic complications of diabetes. We aimed to investigate the subsequent mortality after HCE in the non-elderly diabetic which is still unclear. This retrospective national population-based cohort study reviewed, in Taiwan’s National Health Insurance Research Database, data from 23,079 non-elder patients (≤65 years) with new-onset diabetes between 2000 and 2002: 7693 patients with HCE and 15,386 patients without HCE (1:2). Both groups were compared, and follow-up p...
Source: Endocrine - June 27, 2015 Category: Endocrinology Source Type: research

Blood transfusion and 30-day readmission rate in adult patients hospitalized with sickle cell disease crisis.
CONCLUSION: Our findings point to blood transfusion as a potential means to reduce the 30-day readmission rate among Medicaid patients hospitalized with sickle cell crisis. There is a need for a prospective study to examine the potential benefit and safety of simple blood transfusion for this purpose. PMID: 26126756 [PubMed - as supplied by publisher]
Source: Transfusion - June 30, 2015 Category: Hematology Authors: Nouraie M, Gordeuk VR Tags: Transfusion Source Type: research