Editorial Board
Publication date: May 2020Source: Best Practice & Research Clinical Endocrinology & Metabolism, Volume 34, Issue 3Author(s): (Source: Best Practice and Research Clinical Endocrinology and Metabolism)
Source: Best Practice and Research Clinical Endocrinology and Metabolism - July 23, 2020 Category: Endocrinology Source Type: research

Acquired Forms of Central Diabetes Insipidus: Mechanisms of Disease
Publication date: Available online 10 July 2020Source: Best Practice & Research Clinical Endocrinology & MetabolismAuthor(s): Joseph G. Verbalis (Source: Best Practice and Research Clinical Endocrinology and Metabolism)
Source: Best Practice and Research Clinical Endocrinology and Metabolism - July 11, 2020 Category: Endocrinology Source Type: research

Pediatric adrenocortical tumours
Publication date: Available online 3 July 2020Source: Best Practice & Research Clinical Endocrinology & MetabolismAuthor(s): Emilia Modolo Pinto, Gerard P. Zambetti, Carlos Rodriguez-Galindo (Source: Best Practice and Research Clinical Endocrinology and Metabolism)
Source: Best Practice and Research Clinical Endocrinology and Metabolism - July 5, 2020 Category: Endocrinology Source Type: research

Central Diabetes Insipidus in children: Diagnosis and Management
Publication date: Available online 29 June 2020Source: Best Practice & Research Clinical Endocrinology & MetabolismAuthor(s): Giuseppa Patti, Anastasia Ibba, Gionanni Morana, Flavia Napoli, Daniela Fava, Natascia di Iorgi, Mohamad Maghnie (Source: Best Practice and Research Clinical Endocrinology and Metabolism)
Source: Best Practice and Research Clinical Endocrinology and Metabolism - June 29, 2020 Category: Endocrinology Source Type: research

Thyroid dysfunction following pregnancy and implications for breastfeeding
Publication date: Available online 20 June 2020Source: Best Practice & Research Clinical Endocrinology & MetabolismAuthor(s): Nobuyuki Amino, Naoko Arata (Source: Best Practice and Research Clinical Endocrinology and Metabolism)
Source: Best Practice and Research Clinical Endocrinology and Metabolism - June 22, 2020 Category: Endocrinology Source Type: research

Indications for Treatment of Subclinical Hypothyroidism and Isolated Hypothyroxinaemia in Pregnancy
Publication date: Available online 18 June 2020Source: Best Practice & Research Clinical Endocrinology & MetabolismAuthor(s): Peter N. Taylor, Ilaria Muller, Melanie Nana, Ines Velasco, John H. Lazarus (Source: Best Practice and Research Clinical Endocrinology and Metabolism)
Source: Best Practice and Research Clinical Endocrinology and Metabolism - June 19, 2020 Category: Endocrinology Source Type: research

Genetic forms of neurohypophyseal diabetes insipidus
Publication date: Available online 19 June 2020Source: Best Practice & Research Clinical Endocrinology & MetabolismAuthor(s): Martin Spiess, Nicole Beuret, Jonas Rutishauser (Source: Best Practice and Research Clinical Endocrinology and Metabolism)
Source: Best Practice and Research Clinical Endocrinology and Metabolism - June 19, 2020 Category: Endocrinology Source Type: research

Iodine Status and Supplementation Before, During, and After Pregnancy
Publication date: Available online 19 June 2020Source: Best Practice & Research Clinical Endocrinology & MetabolismAuthor(s): Eduardo Rodriguez-Diaz, Elizabeth N. Pearce (Source: Best Practice and Research Clinical Endocrinology and Metabolism)
Source: Best Practice and Research Clinical Endocrinology and Metabolism - June 19, 2020 Category: Endocrinology Source Type: research

Management of overt hypothyroidism during pregnancy
Publication date: Available online 18 June 2020Source: Best Practice & Research Clinical Endocrinology & MetabolismAuthor(s): Sarah Weiling Li, Shiao Y. Chan (Source: Best Practice and Research Clinical Endocrinology and Metabolism)
Source: Best Practice and Research Clinical Endocrinology and Metabolism - June 19, 2020 Category: Endocrinology Source Type: research

Best Practice review article: TPO Antibody Positivity and Adverse Pregnancy Outcomes
Publication date: Available online 18 June 2020Source: Best Practice & Research Clinical Endocrinology & MetabolismAuthor(s): R.K. Dhillon-Smith, A. Coomarasamy (Source: Best Practice and Research Clinical Endocrinology and Metabolism)
Source: Best Practice and Research Clinical Endocrinology and Metabolism - June 19, 2020 Category: Endocrinology Source Type: research

Interpretation of thyroid function tests during pregnancy
Publication date: Available online 18 June 2020Source: Best Practice & Research Clinical Endocrinology & MetabolismAuthor(s): W. Edward Visser, Robin P. Peeters (Source: Best Practice and Research Clinical Endocrinology and Metabolism)
Source: Best Practice and Research Clinical Endocrinology and Metabolism - June 19, 2020 Category: Endocrinology Source Type: research

Next-generation therapies for adrenocortical carcinoma
Publication date: Available online 18 June 2020Source: Best Practice & Research Clinical Endocrinology & MetabolismAuthor(s): Barbara Altieri, Cristina L. Ronchi, Matthias Kroiss, Martin Fassnacht (Source: Best Practice and Research Clinical Endocrinology and Metabolism)
Source: Best Practice and Research Clinical Endocrinology and Metabolism - June 19, 2020 Category: Endocrinology Source Type: research

Management of neonates born to mothers with thyroid dysfunction, and points for attention during pregnancy
Publication date: Available online 18 June 2020Source: Best Practice & Research Clinical Endocrinology & MetabolismAuthor(s): A.S. Paul van Trotsenburg (Source: Best Practice and Research Clinical Endocrinology and Metabolism)
Source: Best Practice and Research Clinical Endocrinology and Metabolism - June 19, 2020 Category: Endocrinology Source Type: research

Adrenal Tumours
Publication date: Available online 16 June 2020Source: Best Practice & Research Clinical Endocrinology & MetabolismAuthor(s): Massimo Terzolo (Source: Best Practice and Research Clinical Endocrinology and Metabolism)
Source: Best Practice and Research Clinical Endocrinology and Metabolism - June 17, 2020 Category: Endocrinology Source Type: research

Universal Screening for Thyroid Disease SHOULD NOT be Recommended Before and During Pregnancy
Publication date: Available online 17 June 2020Source: Best Practice & Research Clinical Endocrinology & MetabolismAuthor(s): A.H. van der Spek, P.H. Bisschop (Source: Best Practice and Research Clinical Endocrinology and Metabolism)
Source: Best Practice and Research Clinical Endocrinology and Metabolism - June 17, 2020 Category: Endocrinology Source Type: research

Editorial Board
Publication date: March 2020Source: Best Practice & Research Clinical Endocrinology & Metabolism, Volume 34, Issue 2Author(s): (Source: Best Practice and Research Clinical Endocrinology and Metabolism)
Source: Best Practice and Research Clinical Endocrinology and Metabolism - June 1, 2020 Category: Endocrinology Source Type: research

Editorial Board
Publication date: January 2020Source: Best Practice & Research Clinical Endocrinology & Metabolism, Volume 34, Issue 1Author(s): (Source: Best Practice and Research Clinical Endocrinology and Metabolism)
Source: Best Practice and Research Clinical Endocrinology and Metabolism - May 28, 2020 Category: Endocrinology Source Type: research

Adrenocortical tumorigenesis: lessons from genetics
Publication date: Available online 23 May 2020Source: Best Practice & Research Clinical Endocrinology & MetabolismAuthor(s): Crystal D.C. Kamilaris, Fady Hannah-Shmouni, Constantine A. Stratakis (Source: Best Practice and Research Clinical Endocrinology and Metabolism)
Source: Best Practice and Research Clinical Endocrinology and Metabolism - May 24, 2020 Category: Endocrinology Source Type: research

Management of adrenal incidentalomas: working through uncertainty
Publication date: Available online 15 May 2020Source: Best Practice & Research Clinical Endocrinology & MetabolismAuthor(s): Sophie Cambos, Antoine Tabarin (Source: Best Practice and Research Clinical Endocrinology and Metabolism)
Source: Best Practice and Research Clinical Endocrinology and Metabolism - May 16, 2020 Category: Endocrinology Source Type: research

Endocrine causes of secondary hypertension
Publication date: Available online 20 April 2020Source: Best Practice & Research Clinical Endocrinology & MetabolismAuthor(s): Eric Grouzmann (Source: Best Practice and Research Clinical Endocrinology and Metabolism)
Source: Best Practice and Research Clinical Endocrinology and Metabolism - April 29, 2020 Category: Endocrinology Source Type: research

Preface: Endocrine causes of secondary hypertension
Publication date: Available online 20 April 2020Source: Best Practice & Research Clinical Endocrinology & MetabolismAuthor(s): Eric Grouzmann (Source: Best Practice and Research Clinical Endocrinology and Metabolism)
Source: Best Practice and Research Clinical Endocrinology and Metabolism - April 21, 2020 Category: Endocrinology Source Type: research

An overview of 20 years of genetic studies in pheochromocytoma and paraganglioma
Publication date: Available online 10 March 2020Source: Best Practice & Research Clinical Endocrinology & MetabolismAuthor(s): Alexandre Buffet, Nelly Burnichon, Judith Favier, Anne-Paule Gimenez-Roqueplo (Source: Best Practice and Research Clinical Endocrinology and Metabolism)
Source: Best Practice and Research Clinical Endocrinology and Metabolism - April 13, 2020 Category: Endocrinology Source Type: research

Check point inhibitors and autoimmunity: Why endocrinopathies and who is prone to?
Publication date: Available online 5 March 2020Source: Best Practice & Research Clinical Endocrinology & MetabolismAuthor(s): Ruth Percik, Yehuda Shoenfeld (Source: Best Practice and Research Clinical Endocrinology and Metabolism)
Source: Best Practice and Research Clinical Endocrinology and Metabolism - April 9, 2020 Category: Endocrinology Source Type: research

Cushing syndrome: old and new genes
Publication date: Available online 2 April 2020Source: Best Practice & Research Clinical Endocrinology & MetabolismAuthor(s): Christina Tatsi, Chelsi Flippo, Constantine A. Stratakis (Source: Best Practice and Research Clinical Endocrinology and Metabolism)
Source: Best Practice and Research Clinical Endocrinology and Metabolism - April 3, 2020 Category: Endocrinology Source Type: research

Editorial Board
Publication date: December 2019Source: Best Practice & Research Clinical Endocrinology & Metabolism, Volume 33, Issue 6Author(s): (Source: Best Practice and Research Clinical Endocrinology and Metabolism)
Source: Best Practice and Research Clinical Endocrinology and Metabolism - March 14, 2020 Category: Endocrinology Source Type: research

Autoimmunity and the Endocrine System: adrenal, Graves' disease, immune checkpoint
Publication date: Available online 10 March 2020Source: Best Practice & Research Clinical Endocrinology & MetabolismAuthor(s): Alessandro Antonelli, Yehuda Shoenfeld (Source: Best Practice and Research Clinical Endocrinology and Metabolism)
Source: Best Practice and Research Clinical Endocrinology and Metabolism - March 12, 2020 Category: Endocrinology Source Type: research

ASIA syndrome and endocrine autoimmune disorders
Publication date: Available online 11 March 2020Source: Best Practice & Research Clinical Endocrinology & MetabolismAuthor(s): Nicola Luigi Bragazzi, Ashraf Hejly, Abdulla Watad, Mohammed Adawi, Howard Amital, Yehuda Shoenfeld (Source: Best Practice and Research Clinical Endocrinology and Metabolism)
Source: Best Practice and Research Clinical Endocrinology and Metabolism - March 12, 2020 Category: Endocrinology Source Type: research

Disease Monitoring of Primary Aldosteronism
Publication date: Available online 10 March 2020Source: Best Practice & Research Clinical Endocrinology & MetabolismAuthor(s): Gian Paolo Rossi, Maurizio Cesari, Livia Lenzini, Teresa M. Seccia (Source: Best Practice and Research Clinical Endocrinology and Metabolism)
Source: Best Practice and Research Clinical Endocrinology and Metabolism - March 11, 2020 Category: Endocrinology Source Type: research

An Overview Of 20 Years Of Genetic Studies In Pheochromocytoma And Paraganglioma
Publication date: Available online 10 March 2020Source: Best Practice & Research Clinical Endocrinology & MetabolismAuthor(s): Alexandre Buffet, Nelly Burnichon, Judith Favier, Anne-Paule Gimenez-Roqueplo (Source: Best Practice and Research Clinical Endocrinology and Metabolism)
Source: Best Practice and Research Clinical Endocrinology and Metabolism - March 11, 2020 Category: Endocrinology Source Type: research

Management of Thyrotoxicosis During Pregnancy
Publication date: Available online 5 March 2020Source: Best Practice & Research Clinical Endocrinology & MetabolismAuthor(s): Stine Linding Andersen, Louise Knøsgaard (Source: Best Practice and Research Clinical Endocrinology and Metabolism)
Source: Best Practice and Research Clinical Endocrinology and Metabolism - March 5, 2020 Category: Endocrinology Source Type: research

Check point inhibitors and autoimmunity: endocrinopathies and susceptibility
Publication date: Available online 5 March 2020Source: Best Practice & Research Clinical Endocrinology & MetabolismAuthor(s): Ruth Percik, Yehuda Shoenfeld (Source: Best Practice and Research Clinical Endocrinology and Metabolism)
Source: Best Practice and Research Clinical Endocrinology and Metabolism - March 5, 2020 Category: Endocrinology Source Type: research

New perspectives for mitotane treatment of adrenocortical carcinoma
Publication date: Available online 5 March 2020Source: Best Practice & Research Clinical Endocrinology & MetabolismAuthor(s): S. Puglisi, A. Calabrese, V. Basile, A. Pia, G. Reimondo, P. Perotti, M. Terzolo (Source: Best Practice and Research Clinical Endocrinology and Metabolism)
Source: Best Practice and Research Clinical Endocrinology and Metabolism - March 5, 2020 Category: Endocrinology Source Type: research

Cushing's syndrome – Disease monitoring: Recurrence, surveillance with biomarkers or imaging studies
Publication date: Available online 30 January 2020Source: Best Practice & Research Clinical Endocrinology & MetabolismAuthor(s): Oskar Ragnarsson (Source: Best Practice and Research Clinical Endocrinology and Metabolism)
Source: Best Practice and Research Clinical Endocrinology and Metabolism - March 3, 2020 Category: Endocrinology Source Type: research

Surgery for adrenocortical carcinoma: When and how?
Publication date: Available online 3 March 2020Source: Best Practice & Research Clinical Endocrinology & MetabolismAuthor(s): Tiffany J. Sinclair, Andrea Gillis, Wilson M. Alobuia, Hannah Wild, Electron Kebebew (Source: Best Practice and Research Clinical Endocrinology and Metabolism)
Source: Best Practice and Research Clinical Endocrinology and Metabolism - March 3, 2020 Category: Endocrinology Source Type: research

Gestational diabetes insipidus: diagnosis and management
Publication date: Available online 27 February 2020Source: Best Practice & Research Clinical Endocrinology & MetabolismAuthor(s): Sonia Ananthakrishnan (Source: Best Practice and Research Clinical Endocrinology and Metabolism)
Source: Best Practice and Research Clinical Endocrinology and Metabolism - February 28, 2020 Category: Endocrinology Source Type: research

Diagnosis and differential diagnosis of diabetes insipidus: update
Publication date: Available online 28 February 2020Source: Best Practice & Research Clinical Endocrinology & MetabolismAuthor(s): Julie Refardt (Source: Best Practice and Research Clinical Endocrinology and Metabolism)
Source: Best Practice and Research Clinical Endocrinology and Metabolism - February 28, 2020 Category: Endocrinology Source Type: research

The spectrum of low-renin hypertension
Publication date: Available online 25 February 2020Source: Best Practice & Research Clinical Endocrinology & MetabolismAuthor(s): Fabrizio Buffolo, Silvia Monticone, Alessio Pecori, Jacopo Pieroni, Isabel Losano, Giovanni Cavaglià, Martina Tetti, Franco Veglio, Paolo Mulatero (Source: Best Practice and Research Clinical Endocrinology and Metabolism)
Source: Best Practice and Research Clinical Endocrinology and Metabolism - February 26, 2020 Category: Endocrinology Source Type: research

Graves’ disease: Epidemiology, genetic and environmental risk factors and viruses
Publication date: Available online 4 February 2020Source: Best Practice & Research Clinical Endocrinology & MetabolismAuthor(s): Alessandro Antonelli, Silvia Martina Ferrari, Francesca Ragusa, Giusy Elia, Sabrina Rosaria Paparo, Ilaria Ruffilli, Armando Patrizio, Claudia Giusti, Debora Gonnella, Alfonso Cristaudo, Rudy Foddis, Yehuda Shoenfeld, Poupak Fallahi (Source: Best Practice and Research Clinical Endocrinology and Metabolism)
Source: Best Practice and Research Clinical Endocrinology and Metabolism - February 25, 2020 Category: Endocrinology Source Type: research

Controversies and advances in adrenal venous sampling in the diagnostic workup of primary aldosteronism
Publication date: Available online 22 February 2020Source: Best Practice & Research Clinical Endocrinology & MetabolismAuthor(s): Martin Wolley, Moe Thuzar, Michael StowasserAbstractAdrenal venous sampling (AVS) is a key part of the diagnostic workup of primary aldosteronism, distinguishing unilateral from bilateral disease and determining treatment options. Although AVS is a well-established procedure, many aspects remain controversial, including optimal patient selection for the procedure and exactly how AVS is performed and interpreted. Despite the controversies, a growing body of evidence supports the use of AV...
Source: Best Practice and Research Clinical Endocrinology and Metabolism - February 23, 2020 Category: Endocrinology Source Type: research

Autoimmune Addison's disease
Publication date: Available online 30 January 2020Source: Best Practice & Research Clinical Endocrinology & MetabolismAuthor(s): Serena Saverino, Alberto FalorniPrimary adrenal insufficiency (PAI) occurs in 1/5000–1/7000 individuals in the general population. Autoimmune Addison's disease (AAD) is the major cause of PAI and is a major component of autoimmune polyendocrine syndrome type 1 (APS1) and type 2 (APS2). Presence of 21-hydroxylase autoantibodies (21OHAb) identifies subjects with ongoing clinical or pre-clinical adrenal autoimmunity. AAD requires life-long substitutive therapy with two-three daily dose...
Source: Best Practice and Research Clinical Endocrinology and Metabolism - February 15, 2020 Category: Endocrinology Source Type: research

What is the role of medical therapy in adrenal-dependent Cushing's syndrome?
Publication date: Available online 31 January 2020Source: Best Practice & Research Clinical Endocrinology & MetabolismAuthor(s): Leah T. Braun, Martin ReinckeMedical therapy to control hypercortisolism in adrenal Cushing's syndrome is currently not the first-line therapy. However, in many clinical scenarios like pre-surgical treatment, in patients who are not suitable candidates for surgery or in patients with bilateral hyperplasia, medical therapy can be important representing the only viable treatment option. Adrenal steroidogenesis inhibitors and glucocorticoid receptor blockers have been used for many years: me...
Source: Best Practice and Research Clinical Endocrinology and Metabolism - February 15, 2020 Category: Endocrinology Source Type: research

Endocrine disruptors and thyroid autoimmunity
Publication date: Available online 11 February 2020Source: Best Practice & Research Clinical Endocrinology & MetabolismAuthor(s): Salvatore Benvenga, Giusy Elia, Francesca Ragusa, Sabrina Rosaria Paparo, Mattia Maria Sturniolo, Silvia Martina Ferrari, Alessandro Antonelli, Poupak FallahiAbstractMany papers evaluated the effect of the environmental, or occupational endocrine disruptors (ED), on the thyroid gland, that can lead to thyroid autoimmunity. A higher prevalence of “autoimmune thyroid diseases” (AITD) was observed in people living in polluted areas near to petrochemical plants, and in petrochemi...
Source: Best Practice and Research Clinical Endocrinology and Metabolism - February 12, 2020 Category: Endocrinology Source Type: research

Cushing's syndrome: Treatment and new therapeutic approaches
Publication date: Available online 30 January 2020Source: Best Practice & Research Clinical Endocrinology & MetabolismAuthor(s): Amandine Ferriere, Antoine TabarinOvert Cushing's syndrome is a severe condition responsible for multiple comorbidities and increased mortality. Effective treatment is essential to reduce mortality, improve comorbidities and long-term quality of life. Surgical resection of the causal lesion(s) is generally the first-line and most effective treatment to normalize cortisol secretion. Adjunctive symptomatic treatments of co-morbidities are often necessary both during the active phase of the ...
Source: Best Practice and Research Clinical Endocrinology and Metabolism - February 6, 2020 Category: Endocrinology Source Type: research

Graves' disease: epidemiology, genetic and environmental risk factors and viruses
Publication date: Available online 4 February 2020Source: Best Practice & Research Clinical Endocrinology & MetabolismAuthor(s): Alessandro Antonelli, Silvia Martina Ferrari, Francesca Ragusa, Giusy Elia, Sabrina Rosaria Paparo, Ilaria Ruffilli, Armando Patrizio, Claudia Giusti, Debora Gonnella, Alfonso Cristaudo, Rudy Foddis, Yehuda Shoenfeld, Poupak FallahiAbstractGraves' disease (GD) is the most common cause of hyperthyroidism in developed Countries. It is more common between 30-60 years; 5-10 times more frequent in women. The genetic predisposition accounts for 79% of the risk for GD, while environmental factor...
Source: Best Practice and Research Clinical Endocrinology and Metabolism - February 5, 2020 Category: Endocrinology Source Type: research

Adrenocortical hyperplasia: a multifaceted disease
Publication date: Available online 4 February 2020Source: Best Practice & Research Clinical Endocrinology & MetabolismAuthor(s): Isabelle Bourdeau, Stéfanie Parisien-La Salle, André LacroixAbstractAdrenocortical hyperplasia may develop in different contexts. Primary adrenal hyperplasia may be secondary to primary bilateral macronodular adrenocortical hyperplasia (PBMAH) or micronodular bilateral adrenal hyperplasia (MiBAH) which may be divided in primary pigmented nodular adrenocortical disease (PPNAD) and isolated micronodular adrenocortical disease (i-MAD). Both lead to oversecretion of cortisol and...
Source: Best Practice and Research Clinical Endocrinology and Metabolism - February 4, 2020 Category: Endocrinology Source Type: research

Graves' disease: clinical manifestations, immune pathogenesis (cytokines and chemokines) and therapy
Publication date: Available online 4 February 2020Source: Best Practice & Research Clinical Endocrinology & MetabolismAuthor(s): Alessandro Antonelli, Poupak Fallahi, Giusy Elia, Francesca Ragusa, Sabrina Rosaria Paparo, Ilaria Ruffilli, Armando Patrizio, Debora Gonnella, Claudia Giusti, Camilla Virili, Marco Centanni, Yehuda Shoenfeld, Silvia Martina FerrariAbstractGraves’ disease (GD) is characterized by thyrotoxicosis, caused by the presence of circulating thyroid stimulating antibodies (TSAb), that are determinant also in the pathogenesis of its extrathyroidal manifestations [Graves’ ophthalmopathy ...
Source: Best Practice and Research Clinical Endocrinology and Metabolism - February 4, 2020 Category: Endocrinology Source Type: research

Autoimmune Addison’s Disease
Publication date: Available online 30 January 2020Source: Best Practice & Research Clinical Endocrinology & MetabolismAuthor(s): Serena Saverino, Alberto FalorniAbstractPrimary adrenal insufficiency (PAI) occurs in 1/5,000-1/7,000 individuals in the general population. Autoimmune Addison’s disease (AAD) is the major cause of PAI and is a major component of autoimmune polyendocrine syndrome type 1 (APS1) and type 2 (APS2). Presence of 21-hydroxylase autoantibodies (21OHAb) identifies subjects with ongoing clinical or pre-clinical adrenal autoimmunity. AAD requires life-long substitutive therapy with two-three ...
Source: Best Practice and Research Clinical Endocrinology and Metabolism - January 31, 2020 Category: Endocrinology Source Type: research

Cushing’s syndrome – Disease monitoring: Recurrence, surveillance with biomarkers or imaging studies
Publication date: Available online 30 January 2020Source: Best Practice & Research Clinical Endocrinology & MetabolismAuthor(s): Oskar RagnarssonAbstractPituitary surgery is the first-line treatment for patients with Cushing’s disease. For patients who are not considered candidates for pituitary surgery, pituitary radiation and bilateral adrenalectomy are further treatment alternatives. Not all patients are cured with pituitary surgery, and a substantial number of patients develop recurrence, sometimes many years after an apparently successful treatment. The same applies to patients treated with radiotherapy....
Source: Best Practice and Research Clinical Endocrinology and Metabolism - January 31, 2020 Category: Endocrinology Source Type: research

Cushing’s syndrome: treatment and new therapeutic approaches
Publication date: Available online 30 January 2020Source: Best Practice & Research Clinical Endocrinology & MetabolismAuthor(s): Amandine Ferriere, Antoine TabarinAbstractOvert Cushing’s syndrome is a severe condition responsible for multiple comorbidities and increased mortality. Effective treatment is essential to reduce mortality, improve comorbidities and long-term quality of life. Surgical resection of the causal lesion(s) is generally the first-line and most effective treatment to normalize cortisol secretion. Adjunctive symptomatic treatments of co-morbidities are often necessary both during the active...
Source: Best Practice and Research Clinical Endocrinology and Metabolism - January 31, 2020 Category: Endocrinology Source Type: research

Thyroid-associated ophthalmopathy: emergence of teprotumumab as a promising medical therapy
Publication date: Available online 31 January 2020Source: Best Practice & Research Clinical Endocrinology & MetabolismAuthor(s): Terry J. SmithAbstractThyroid-associated ophthalmopathy (TAO) remains a vexing autoimmune component of Graves’ disease that can diminish the quality of life as a consequence of its impact on visual function, physical appearance and emotional well-being. Because of its relative rarity and variable presentation, the development of highly effective and well-tolerated medical therapies for TAO has been slow relative to other autoimmune diseases. Contributing to the barriers of greater i...
Source: Best Practice and Research Clinical Endocrinology and Metabolism - January 31, 2020 Category: Endocrinology Source Type: research