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Total 365 results found since Jan 2013.

Microcos paniculata: a review on its botany, traditional uses, phytochemistry and pharmacology
Publication date: August 2019Source: Chinese Journal of Natural Medicines, Volume 17, Issue 8Author(s): Ying-Qun JIANG, E-Hu LIUAbstractThe shrub Microcos paniulata (MPL; Tiliaceae), distributed in south China, south and southeast Asia, yields a phytomedicine used to treat heat stroke, fever, dyspepsia, diarrhea, insect bites and jaundice. Phytochemical investigations on different parts of MPL indicate the presence of flavonoids, alkaloids, triterpenoids and organic acids. The MPL leaves, fruits, barks and roots extracts showed antidiarrheal, antimicrobial and insecticidal, anti-inflammation, hepatoprotective, cardiovascul...
Source: Chinese Journal of Natural Medicines - August 30, 2019 Category: Complementary Medicine Source Type: research

Lifestyle Risk Behaviors Among Stroke Survivors With and Without Diabetes
Conclusions Prevalence of select lifestyle risk behaviors exceeds 50% in adults with stroke but is higher in adults with diabetes compared with adults without diabetes. Effective interventions, community programs, and healthcare policy are needed to promote lifestyle management in adults with stroke, particularly among those with diabetes.
Source: American Journal of Physical Medicine and Rehabilitation - August 17, 2019 Category: Rehabilitation Tags: Original Research Articles Source Type: research

Lifestyle Risk Behaviors Among Stroke Survivors With and Without Diabetes.
CONCLUSIONS: Prevalence of select lifestyle risk behaviors exceeds 50% in adults with stroke but is higher in adults with diabetes compared with adults without diabetes. Effective interventions, community programs, and healthcare policy are needed to promote lifestyle management in adults with stroke, particularly among those with diabetes. PMID: 31415289 [PubMed - in process]
Source: Health Physics - August 16, 2019 Category: Physics Authors: Bailey RR, Phad A, McGrath R, Ford AL, Tabak R, Haire-Joshu D Tags: Am J Phys Med Rehabil Source Type: research

Health Behaviors in Rural Appalachia.
CONCLUSIONS: This community-based sample demonstrated elevated behavioral risk factors that likely contribute to some of the nation's highest rates of premature mortality. Despite suboptimal dietary intake and physical activity, results indicate some potential leverage points between the generations that may be used to improve health. For example, the older generation could benefit from engaging with their younger relatives in physical activities while advocating for a better-rounded diet. Given traditions of intergenerational connectedness, mutual aid, and self-reliance, transmission of healthier behaviors across the gene...
Source: Southern Medical Journal - August 5, 2019 Category: General Medicine Tags: South Med J Source Type: research

Polyphenols regulate endothelial functions and reduce the risk of cardiovascular disease.
CONCLUSION: High intake of dietary polyphenols may help prevent CVD. Polyphenols inhibit endothelial dysfunction and induce vascular endothelium-dependent vascular relaxation viz. redox regulation and nitric oxide production. The polyphenol-induced healthy endothelial cell function may be related to CVD prevention. PMID: 31333108 [PubMed - as supplied by publisher]
Source: Current Pharmaceutical Design - July 20, 2019 Category: Drugs & Pharmacology Authors: Yamagata K Tags: Curr Pharm Des Source Type: research

Associations for BCO2, PCSK9, and TR1B1 Polymorphism and Lifestyle Factors with Ischemic Stroke: A Nested Case-Control Study.
CONCLUSION: Polymorphisms in BCO2 and TRIB1 and fruits/vegetables intake were associated with IS. These results provide the theoretical basis for gene screening to prevent chronic cerebrovascular diseases. PMID: 31250580 [PubMed - in process]
Source: Yonsei Medical Journal - June 30, 2019 Category: Universities & Medical Training Authors: Zhao TY, Li Z, Lei S, Huang L, Yang L Tags: Yonsei Med J Source Type: research

Natural Products from Mediterranean Diet: From anti-hyperlipidemic Agents to Dietary Epigenetic Modulators.
CONCLUSION: Many of the natural products found in Mediterranean diet contribute in the treatment of hyperlipidemia, however the effects seem to be dose and/or consumption frequency related, which highlights the fact that a healthy diet can only be effective in reversing disease markers if it is consistent and within the frame of a healthy life style. PMID: 31264546 [PubMed - as supplied by publisher]
Source: Current Pharmaceutical Biotechnology - June 27, 2019 Category: Biotechnology Authors: Georgia-Eirini D, Athina S, Wim VB, Christos K, Theodoros C Tags: Curr Pharm Biotechnol Source Type: research

Implementation of a Brazilian Cardioprotective nutritional (BALANCE) program for improvement on quality of diet and secondary prevention of cardiovascular events: A randomized, multicentre trial
ConclusionsThe BALANCE Program only slightly improved adherence to a healthy diet in patients with established CVD, and had no significant effect on the incidence of cardiovascular events or death.
Source: American Heart Journal - June 21, 2019 Category: Cardiology Source Type: research

Coronary heart disease and stroke disease burden attributable to fruit and vegetable intake in Japan: projected DALYS to 2060
This study aimed to project the reduction in the CVD burden under different scenar...
Source: BMC Public Health - June 7, 2019 Category: Consumer Health News Authors: Xiuting Mo, Ruoyan Tobe Gai, Kimi Sawada, Yoshimutsu Takahashi, Sharon E. Cox, Takeo Nakayama and Rintaro Mori Tags: Research article Source Type: research

The dietary transition and its association with cardiometabolic mortality among Chinese adults, 1982–2012: a cross-sectional population-based study
Publication date: Available online 10 May 2019Source: The Lancet Diabetes & EndocrinologyAuthor(s): Yuna He, Yanping Li, Xiaoguang Yang, Elena C Hemler, Yuehui Fang, Liyun Zhao, Jian Zhang, Zhenyu Yang, Zhu Wang, Li He, Jing Sun, Dong D Wang, Jingzhong Wang, Jianhua Piao, Xiaofeng Liang, Gangqiang Ding, Frank B HuSummaryBackgroundFew studies have used nationally representative data to describe dietary trends and the related cardiometabolic mortality burden in China. Thus, we aimed to characterise the trends in disease-related dietary factors as well as their associated disease burden among Chinese adults from 1982 to 2012....
Source: The Lancet Diabetes and Endocrinology - May 12, 2019 Category: Endocrinology Source Type: research

Myricetin ameliorated Ischemia/Reperfusion-Induced Brain Endothelial Permeability by improvement of eNOS uncoupling and activation eNOS/NO
In conclusion, Myricetin showed significant protect effect on ischemia/reperfusion-induced brain endothelial permeability, and related to simultaneously regulated Akt pathway and improvement of eNOS uncoupling through Nrf2 pathway.
Source: Journal of Pharmacological Sciences - May 4, 2019 Category: Drugs & Pharmacology Source Type: research

Assessment of the risk factors in the daily life of stroke patients based on an optimized decision tree.
CONCLUSIONS: It is anticipated that the proposed system could help in reducing the risk, mortality, and disability of stroke, and provide clinical decision support for the treatment of stroke. PMID: 31045550 [PubMed - as supplied by publisher]
Source: Technology and Health Care - April 28, 2019 Category: Medical Devices Authors: Shao Z, Chen C, Chen W, Li W, Ren H, Chen W Tags: Technol Health Care Source Type: research

Intake of 12 food groups and disability-adjusted life years from coronary heart disease, stroke, type 2 diabetes, and colorectal cancer in 16 European countries
AbstractOur aim was to estimate and rank 12 food groups according to disability-adjusted life years (DALYs) from coronary heart disease (CHD), stroke, type 2 diabetes (T2D), and colorectal cancer (CRC) in 16 European countries. De novo published non-linear dose –response meta-analyses of prospective studies (based on 297 primary reports), and food consumption data from the European Food Safety Authority Comprehensive European Food Consumption Database in Exposure Assessment, and DALY estimates from the Institute for Health Metrics and Evaluation were use d. By implementing disease-specific counterfactual scenarios of the...
Source: European Journal of Epidemiology - April 26, 2019 Category: Epidemiology Source Type: research

Want to Live Longer? Science Says to Do These 5 Things
When it comes to staying healthy, most people have the same motivation: living as long and fulfilling a life as possible. And while science has yet to find a true fountain of youth, researchers have identified certain behaviors that can increase longevity. One study, published in the journal Circulation last year, even argued that adhering to just five healthy habits could extend your lifespan by roughly a decade. Here’s what they are, and what research to date says about living your longest life. Eating a healthy diet Diet is strongly linked to longevity. Research has long suggested that following a Mediterranean di...
Source: TIME: Health - April 19, 2019 Category: Consumer Health News Authors: Jamie Ducharme Tags: Uncategorized Longevity Source Type: news

Geniposide Alleviates Glucocorticoid-Induced Inhibition of Osteogenic Differentiation in MC3T3-E1 Cells by ERK Pathway
Conclusion In summary, we demonstrated that geniposide alleviated GC-induced osteogenic suppression in MC3T3-E1 cells. The effects of geniposide were at least partially associated with activating ERK signaling pathway via GLP-1 receptor. Geniposide might be a potential therapeutic agent for protection against GC-induced osteoporosis. Author Contributions BX, DX, CZ, and LW participated in research design. BX, JW, YL, XW, and ZZ conducted the experiments. BX, DX, and LW contributed new reagents or analytic tools and wrote or contributed to the writing of the manuscript. BX, JW, CZ, and DX performed the data analysis. Fu...
Source: Frontiers in Pharmacology - April 17, 2019 Category: Drugs & Pharmacology Source Type: research