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Total 550 results found since Jan 2013.

Effective treatment of intractable diseases using nanoparticles to interfere with vascular supply and angiogenic process
Eur J Med Res. 2022 Nov 4;27(1):232. doi: 10.1186/s40001-022-00833-6.ABSTRACTAngiogenesis is a vital biological process involving blood vessels forming from pre-existing vascular systems. This process contributes to various physiological activities, including embryonic development, hair growth, ovulation, menstruation, and the repair and regeneration of damaged tissue. On the other hand, it is essential in treating a wide range of pathological diseases, such as cardiovascular and ischemic diseases, rheumatoid arthritis, malignancies, ophthalmic and retinal diseases, and other chronic conditions. These diseases and disorder...
Source: Cell Research - November 5, 2022 Category: Cytology Authors: Ahmad Hoseinzadeh Hamed Ghoddusi Johari Mohammad Hossein Anbardar Lobat Tayebi Ehsan Vafa Milad Abbasi Ahmad Vaez Ali Golchin Ali Mohammad Amani Ali Jangjou Source Type: research

Transgenic animal models to explore and modulate the blood brain and blood retinal barriers of the CNS
AbstractThe unique environment of the brain and retina is tightly regulated by blood –brain barrier and the blood-retinal barrier, respectively, to ensure proper neuronal function. Endothelial cells within these tissues possess distinct properties that allow for controlled passage of solutes and fluids. Pericytes, glia cells and neurons signal to endothelial cells (ECs) to form an d maintain the barriers and control blood flow, helping to create the neurovascular unit. This barrier is lost in a wide range of diseases affecting the central nervous system (CNS) and retina such as brain tumors, stroke, dementia, and in the ...
Source: Fluids and Barriers of the CNS - November 1, 2022 Category: Neuroscience Source Type: research

The impact of initial admission department on the management and prognosis of retinal artery occlusion
CONCLUSIONS: The study demonstrated that the visual prognosis of RAO was devastating regardless of the neurology and ophthalmology department. Given the admission delay, inadequate management, and high risk of cardiovascular risk factors and stroke, stroke centers should be recommended as initial admission departments for RAO patients.PMID:36305143 | DOI:10.2174/1567202620666221027091249
Source: Current Neurovascular Research - October 28, 2022 Category: Neurology Authors: Yanqin Liu Shuju Dong Yaxi Luo Yanbo Li Changling Li Dong Zhou Li He Source Type: research

Eye signs in stroke
Rajeshwar Sahonta, Ivy Sebastian, Sanjit Aaron, Appaswamy T Prabakhar, Anupriya Arthur, Jeyaraj D PandianAnnals of Indian Academy of Neurology 2022 25(8):94-100 A large part of the central nervous system is involved in the normal functioning of the vision, and hence vision can be affected in a stroke patient. Transient visual symptoms can likewise be a harbinger of stroke and prompt rapid evaluation for the prevention of recurrent stroke. A carotid artery disease can manifest as transient monocular visual loss (TMVL), central retinal artery occlusion (CRAO), anterior ischemic optic neuropathy or ocular ischemic syndrome (...
Source: Annals of Indian Academy of Neurology - October 19, 2022 Category: Neurology Authors: Rajeshwar Sahonta Ivy Sebastian Sanjit Aaron Appaswamy T Prabakhar Anupriya Arthur Jeyaraj D Pandian Source Type: research

Retinoic Acid Prevents the Neuronal Damage Through the Regulation of Parvalbumin in an Ischemic Stroke Model
In conclusion, retinoic acid contributes to the preservation of neurons from ischemic stroke by controlling parvalbumin expression and apoptosis-related proteins.PMID:36245066 | DOI:10.1007/s11064-022-03769-9
Source: Neurochemical Research - October 16, 2022 Category: Neuroscience Authors: Ju-Bin Kang Dong-Ju Park Phil-Ok Koh Source Type: research