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EP61 Direct carotid puncture for mechanical thrombectomy in acute ischaemic stroke: a single centre experience and review of the literature
ConclusionDirect carotid puncture is an effective and generally safe approach for EVT, with major access-site related complications seen in <5% of the cases. It should be considered as a bailout technique or primary access approach in selected cases.ReferencesAkpinar CK, et al. Direct common carotid artery puncture: rescue mechanical thrombectomy strategy in acute ischemic stroke. Neurointervention 2020;15(2):60–66.Cord BJ, et al. Direct carotid puncture for mechanical thrombectomy in acute ischemic stroke patients with prohibitive vascular access. J Neurosurg 2020:1–11.Miszczuk M, et al. Direct puncture of ...
Source: Journal of NeuroInterventional Surgery - August 24, 2021 Category: Neurosurgery Authors: Chan, J., Cheung, I., Chu, Y., Lee, R. Tags: Treatment Source Type: research
The Hyperbaric Oxygen Therapy Protocol in Acute Central Retinal Artery Occlusion Seen within 24 Hours at a Tertiary Institution
We read with interest the research article entitled “Acute Central Retinal Artery Occlusion Seen within 24 h at a Tertiary Institution”,1 it was an original study focusing on the timing of emergency hospital attendance after acute Central Retinal Artery Occlusion (CRAO) onset from sudden vision loss. The authors were particularly concerned on th e CRAO protocol of intravenous thrombolysis and diagnostic pathway. However, as the Hyperbaric Oxygen Therapy (HBOT) practitioners running the HORA study,2–5 we are more interested in the HBOT protocol adopted in the authors’ tertiary institution, which was not mentioned in the article.
Source: Journal of Stroke and Cerebrovascular Diseases - August 13, 2021 Category: Neurology Authors: Sunny Chi Lik Au Tags: Letter to the Editor Source Type: research
Peptide5 attenuates rtPA related brain microvascular endothelial cells reperfusion injury via the Wnt/ β-catenin signalling pathway
CONCLUSION: This study showed that the application of peptide5 maintained cell viability and permeability associated with rtPA treatment, revealing a possible pathway that could be exploited to limit rtPA-related endothelial cell injury during ischemic stroke. Furthermore, the altered Wnt/β-catenin signaling pathway demonstrated that signaling pathways associated with Cx43 might have potential applications in the future. This study may provide a new way to attenuate HT and assist the application of rtPA in ischemic stroke.PMID:34370635 | DOI:10.2174/1567202618666210809115305
Source: Current Neurovascular Research - August 9, 2021 Category: Neurology Authors: Weimin Ren Chuyi Huang Heling Chu Yuping Tang Xiaobo Yang Source Type: research
