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Harnessing Unruly Digital Health Data
As medical devices and digital apps increasingly merge, patients, healthcare professionals, and medtech companies find themselves armed with more and richer data. Digitally-enabled medical devices can record data which, if used properly, facilitates more personalized care and drives better outcomes for patients. These advanced devices also provide medtech companies with the information they need to do two important things: continually optimize product performance and prove to key stakeholders the efficacy and value of their products. And more of these devices are on the way.
Let’s consider two examples. A...
Source: MDDI - September 3, 2019 Category: Medical Devices Authors: Dan Schulman and Piotr Kula Tags: Digital Health Source Type: news
Burden of smoking in Brazil and potential benefit of increasing taxes on cigarettes for the economy and for reducing morbidity and mortality.
In conclusion, the burden of disease and economic losses associated with smoking is high in Brazil, and tax increases are capable of averting deaths, illness, and costs to society.
PMID: 31483047 [PubMed - in process]
Source: Cadernos de Saude Publica - August 28, 2019 Category: International Medicine & Public Health Authors: Pinto M, Bardach A, Palacios A, Biz A, Alcaraz A, Rodriguez B, Augustovski F, Pichon-Riviere A Tags: Cad Saude Publica Source Type: research
Health system challenges affecting rehabilitation services in South Africa.
This article presents challenges and solutions to ensure that South Africa can meet WHO 2030 Rehabilitation Goals for equitable provision of effective public rehabilitation services using the WHO's health system building block framework. IMPLICATIONS FOR REHABILITATION To meet the challenge of providing rehabilitation for those in need requires country-specific, strategic, evidence-informed, and planned decisions in terms of best investment for highest return. Whilst there is sound international evidence for best-practice rehabilitation care, country-specific strategies are required to identify and address local barriers t...
Source: Disability and Rehabilitation - August 2, 2019 Category: Rehabilitation Authors: Morris LD, Grimmer KA, Twizeyemariya A, Coetzee M, Leibbrandt DC, Louw QA Tags: Disabil Rehabil Source Type: research
NAMPT as a Dedifferentiation-Inducer Gene: NAD+ as Core Axis for Glioma Cancer Stem-Like Cells Maintenance
Conclusion and Perspectives
Gliomas are the most prevalent primary brain cancer in adults and include a broad category of tumors including astrocytoma, oligodendroglioma, and GBM. Regardless of tumor aggressiveness, malignancy, and infiltration, these glia-derived tumors rarely exceed a median survival time of 12–14 months. Driven by the infiltrative nature of these tumors, the clinical approach is difficult and relapses often occur with fatal consequences. These unsuccessful attempts to control glioma's fate have fostered research looking for more effective therapies.
(GSCs) are a small subset of CD133&#...
Source: Frontiers in Oncology - May 2, 2019 Category: Cancer & Oncology Source Type: research
The Outcome of Status Epilepticus and Long-Term Follow-Up
Conclusion: This study highlights the importance of regular care and patient follow-up.
Introduction
Status epilepticus (SE) is a condition and most extreme form of epilepsy (1), which leads to abnormal and prolonged seizure (at least 5 min). In case SE persists over 30 min, it may have severe long-term consequences (2). Referring to the new classification scheme of SE, there are two operational dimensions of the definition: time point 1 (T1) is associated with abnormally prolonged seizure, when therapy should be initiated, while time point 2 (T2) is related to the time of on-going seizure activity involving a risk...
Source: Frontiers in Neurology - April 25, 2019 Category: Neurology Source Type: research
A Copernican Approach to Brain Advancement: The Paradigm of Allostatic Orchestration
The objective of this presentation is to explore historical, scientific, interventional, and other differences between the two paradigms, so that innovators, researchers, practitioners, policy-makers, patients, end-users, and others can gain clarity with respect to both the explicit and implicit assumptions associated with brain advancement agendas of any kind.
Over the course of three decades, a series of brain-centric, evolution-inspired insights have been articulated with increasing refinement, as principles of allostasis (Sterling and Eyer, 1988; Sterling, 2004, 2012, 2014). Allostasis recognizes that the role of the ...
Source: Frontiers in Human Neuroscience - April 25, 2019 Category: Neuroscience Source Type: research
Influence of Combined Transcranial Direct Current Stimulation and Motor Training on Corticospinal Excitability in Children With Unilateral Cerebral Palsy
Conclusion
This proof-of-principle study evaluated the influence of cathodal contralesional tDCS on corticospinal excitability in pediatric participants with UCP. A hypothesized decrease in contralesional excitability was noted in participants in the Active+CIMT group, however, the efficacy of tDCS to modulate corticospinal excitability was not statistically different than the Sham+CIMT group. A more detailed understanding of how tDCS impacts M1 neurophysiology will be essential to inform future clinical trials on the optimal dosing parameters, based on individual brain circuitry, to explore the potential functional benef...
Source: Frontiers in Human Neuroscience - April 23, 2019 Category: Neuroscience Source Type: research
Influence of Sex on Stroke Prognosis: A Demographic, Clinical, and Molecular Analysis
Conclusion
Our data suggest that women who suffer from IS present with a poorer functional outcome than men at 3-months, regardless of other preclinical and clinical factors during the acute phase. These relationships seem to be mediated by atrial dysfunction and inflammation. The inflammatory response is slightly higher in women; however, there are no sex differences in their functional behavior. There is a probable relationship between the molecular marker of atrial dysfunction NT-proBNP and worse functional outcome in women, and the connection seems to be more important in cardioembolic stroke patients.
In patients wi...
Source: Frontiers in Neurology - April 16, 2019 Category: Neurology Source Type: research
WHO/ILO work-related burden of disease and injury: Protocol for systematic reviews of exposure to occupational noise and of the effect of exposure to occupational noise on cardiovascular disease.
aga JU
Abstract
BACKGROUND: The World Health Organization (WHO) and the International Labour Organization (ILO) are developing a joint methodology for estimating the national and global work-related burden of disease and injury (WHO/ILO joint methodology), with contributions from a large network of experts. In this paper, we present the protocol for two systematic reviews of parameters for estimating the number of deaths and disability-adjusted life years from cardiovascular disease attributable to exposure to occupational noise, to inform the development of the WHO/ILO joint methodology.
OBJECTIVES: We aim t...
Source: Environment International - January 22, 2019 Category: Environmental Health Authors: Teixeira LR, Azevedo TM, Bortkiewicz A, Corrêa da Silva DT, de Abreu W, de Almeida MS, de Araujo MAN, Gadzicka E, Ivanov ID, Leppink N, Macedo MRV, de S Maciel EMG, Pawlaczyk-Łuszczyńska M, Pega F, Prüss-Üstün AM, Siedlecka J, Stevens GA, Ujita Y, B Tags: Environ Int Source Type: research
Palm oil and dietary change: Application of an integrated macroeconomic, environmental, demographic, and health modelling framework for Thailand
Publication date: Available online 18 January 2019Source: Food PolicyAuthor(s): Henning Tarp Jensen, Marcus R. Keogh-Brown, Bhavani Shankar, Wichai Aekplakorn, Sanjay Basu, Soledad Cuevas, Alan D. Dangour, Shabbir H. Gheewala, Rosemary Green, Edward J.M. Joy, Nipa Rojroongwasinkul, Nalitra Thaiprasert, Richard D. SmithAbstractPalm oil is a cooking oil and food ingredient in widespread use in the global food system. However, as a highly saturated fat, palm oil consumption has been associated with negative effects on cardiovascular health, while large scale oil palm production has been linked to deforestation. We construct a...
Source: Food Policy - January 20, 2019 Category: Food Science Source Type: research
Application of Muse Cell Therapy to Stroke.
Authors: Niizuma K, Borlongan CV, Tominaga T
Abstract
Stroke is defined as a sudden onset of neurologic deficits arising from cerebrovascular complications. It is the second common cause of death around the world and the major cause of disability. Because brain is an organ with complicated neural networks and neurons are highly differentiated, it has been traditionally considered to possess a limited potential for regeneration. The number of stroke patients is increasing, and stroke represents a serious problem from the viewpoint of the national medical economy. Even with the current sophisticated treatments, more ...
Source: Advances in Experimental Medicine and Biology - November 30, 2018 Category: Research Tags: Adv Exp Med Biol Source Type: research
‘ Meat Taxes ’ Would Save Lives And Cut Health Care Costs, Study Says
(CNN) — It would drive up the price of your barbecue but a global “meat tax” could save 220,000 lives and cut health care bills by $41 billion each year, according to a new study.
The numbers are based on evidence that links meat consumption to increased risk of heart disease, cancer, stroke and diabetes.
Three years ago, the World Health Organization declared red meat such as beef, lamb and pork to be carcinogenic when eaten in processed forms, including sausages, bacon and beef jerky.
Health officials have also declared that unprocessed red meat like steak and burgers are “probably” carcinog...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - November 7, 2018 Category: Consumer Health News Authors: Health – CBS Boston Tags: Health Offbeat Local TV Meat Source Type: news
Did post-Soviet Russians drink themselves to death?
By Vladimir Popov and Jomo Kwame SundaramMOSCOW and KUALA LUMPUR, Oct 23 2018 (IPS)Although initially obscured by The Economist, among others, the sudden and unprecedented increase in Russian adult male mortality during 1992-1994 is no longer denied. Instead, the debate is now over why?Having advocated ‘shock therapy’, a ‘big bang’, ‘sudden’ or rapid post-Soviet transition, Jeffrey Sachs and others have claimed that the sudden collapse in Russian adult male life expectancy was due to a sudden increase in alcohol consumption, playing into popular foreign images of vodka-binging Russian men. In Russia, vodka is a...
Source: IPS Inter Press Service - Health - October 23, 2018 Category: International Medicine & Public Health Authors: Vladimir Popov and Jomo Kwame Sundaram Tags: Development & Aid Economy & Trade Europe Global Governance Headlines Health TerraViva United Nations Source Type: news
Zero Hunger: our actions today are our future tomorrow
This article is part of a series of opinion pieces to mark World Food Day October 16 José Graziano da Silva is Director-General of the Food and Agriculture Organization of the United NationsThe post Zero Hunger: our actions today are our future tomorrow appeared first on Inter Press Service.
Source: IPS Inter Press Service - Health - October 15, 2018 Category: International Medicine & Public Health Authors: Jose Graziano da Silva Tags: Development & Aid Economy & Trade Editors' Choice Featured Food & Agriculture Global Headlines Health Poverty & SDGs TerraViva United Nations World Food Day 2018 Source Type: news
An update on physical health and economic consequences of overweight and obesity
Publication date: Available online 5 May 2018Source: Diabetes & Metabolic Syndrome: Clinical Research & ReviewsAuthor(s): Dinh-Toi Chu, Nguyen Thi Minh Nguyet, Thien Chu Dinh, Nguyen Vu Thai Lien, Khanh-Hoang Nguyen, Vo Truong Nhu Ngoc, Yang Tao, Le Hoang Son, Duc-Hau Le, Vu Bich Nga, Adam Jurgoński, Quoc-Hung Tran, Pham Van Tu, Van-Huy PhamAbstractOverweight and obesity (OW and OB) have been on the increase globally and posed health risks to the world’s population of all ages, including pre-born babies, children, adolescents, adults and elderly people, via their comorbid conditions. Excellent examples of comorbidities ...
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - July 10, 2018 Category: Endocrinology Source Type: research
