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Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation

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Total 298 results found since Jan 2013.

Talking and tDCS Treatment for Stroke Survivors with Aphasia
This pilot study involves the use of transcranial direct current stimulation (tDCS), in conjunction with speech-language therapy for aphasia. In recent years, researchers have investigated the use of noninvasive brain stimulation techniques such as TMS (transcranial magnetic stimulation) and tDCS for the modulation of brain activity to improve function post stroke. In contrast to TMS, administering speech-language therapy at the same time is feasible with tDCS since the environment is quiet. Although several studies include behavioral therapy, the specifics regarding the speech-language treatment have not been described, a...
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - March 1, 2014 Category: Neurology Authors: Elizabeth Galletta, Amy Vogel, Steven Baumann Tags: Abstracts Presented at NYC Neuromodulation 2013 Source Type: research

Speech-language neurorehabilitation: Preliminary results of tDCS and robotic arm training in single left ischemic stroke.
We report a preliminary trans-disciplinary study investigating changes in measures of speech/language processing subsequent to anodal or sham tDCS preceding robotic arm treatment.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - March 1, 2014 Category: Neurology Authors: Carolyn Falconer, Adam Buchwald, Dylan Edwards Tags: Abstracts Presented at NYC Neuromodulation 2013 Source Type: research

HD-tDCS to enhance behavioral treatment for aphasia: A feasibility study
Transcranial direct current stimulation (tDCS) enhances treatment outcomes post-stroke. Effects depend largely on which cortical areas are targeted. Feasibility and tolerability of high-definition (HD) tDCS, a technique that is thought to increase current focality and intensity, for consecutive weekdays as an adjunct to behavioral treatment in a clinical population has not been demonstrated.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - March 1, 2014 Category: Neurology Authors: Jessica D. Richardson, Abhishek Datta, Jacek Dmochowski, Lucas Parra, Julius Fridriksson Tags: Abstracts Presented at NYC Neuromodulation 2013 Source Type: research

Ipsilateral corticomotor neurophysiology in children with perinatal stroke
Perinatal stroke (PS) causes most hemiparetic cerebral palsy. Persistence of ipsilateral corticomotor connections from unlesioned hemisphere to aff5cted hand are common and associated with worse function. Ipsilateral cortical neurophysiology is poorly understood and a therapeutic target. We hypothesized that ipsilateral motor cortex demonstrates the same neurophysiological properties as normal contralateral systems.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - March 1, 2014 Category: Neurology Authors: O. Damji, A. Kirton Tags: Abstracts Presented at NYC Neuromodulation 2013 Source Type: research

Treatment of severe expressive dysphasia with rTMS and language therapy after childhood stroke.
Childhood stroke causes lifelong language disability. Expressive dysphasia accompanies left inferior frontal gyrus (IFG/Broca) injury. Recovery and therapy effects may relate to interhemispheric balance with homologous, contralesional IFG. Inhibiting contralesional IFG with repetitive transcranial magnetic stimulation (rTMS) may improve adult stroke dysphasia but is unexplored in children.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - March 1, 2014 Category: Neurology Authors: Helen L. Carlson, Aleksandra Mineyko, Omar Damji, Zeanna Zadavji, Rebecca Patzelt, Anya Mazur-Mosiewicz, Adam Kirton Tags: Abstracts Presented at NYC Neuromodulation 2013 Source Type: research

Characterizing the Mechanisms of Central and Peripheral Forms of Neurostimulation in Chronic Dysphagic Stroke Patients
Conclusions: In this mechanistic study, an increase in corticobulbar excitability the unaffected projection was correlated with the improvement in swallowing safety (P = .001, rho = −.732), but modality-specific differences were observed. Paradigms providing peripheral input favored change in neurophysiological and behavioral outcome measures in chronic dysphagia patients. Further larger cohort studies of neurostimulation in chronic dysphagic stroke are imperative.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - October 14, 2013 Category: Neurology Authors: Emilia Michou, Satish Mistry, Samantha Jefferson, Pippa Tyrrell, Shaheen Hamdy Tags: Original Research Source Type: research

Connectivity between Right Inferior Frontal Gyrus and Supplementary Motor Area Predicts After-Effects of Right Frontal Cathodal tDCS on Picture Naming Speed
Conclusions: The results support the notion that the after-effects of tDCS on brain function are at least in part determined by the anatomical and functional connectivity of the targeted region.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - September 27, 2013 Category: Neurology Authors: Charlotte Rosso, R. Valabregue, C. Arbizu, S. Ferrieux, P. Vargas, F. Humbert, Y. Attal, A. Messé, C. Zavanone, S. Meunier, L. Cohen, C. Delmaire, A. Thielscher, D.M. Herz, H.R. Siebner, Y. Samson, S. Lehéricy Tags: Original Research Source Type: research

Anodal Transcranial Direct Current Stimulation (tDCS) Over the Motor Cortex Increases Sympathetic Nerve Activity
Conclusions: Anodal tDCS of the motor cortex shifts autonomic nervous system balance toward sympathetic dominance due at least in part to an increase in sympathetic output. These results suggest further investigation is warranted on tDCS use in patient groups with potential autonomic dysfunction, such as stroke patients.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - September 19, 2013 Category: Neurology Authors: Jennifer A. Clancy, Robyn Johnson, Rachael Raw, Susan A. Deuchars, Jim Deuchars Tags: Original Research Source Type: research

A Non-Epileptiform Event in the Course of rTMS: A Case for Close Physician Monitoring
We present the following case to demonstrate the importance of having physician supervision of patients undergoing repetitive transcranial magnetic stimulation (rTMS) treatments. The patient was a married 60-year-old male with a diagnosis of Major Depressive Disorder and Generalized Anxiety Disorder who had continuous symptoms of depression since the early 1980s despite receiving at least 7 adequate antidepressant treatments. The patient had several comorbid medical conditions. The patient did not have any previous history of seizure, stroke, an abnormal EEG, head injury, neurosurgical procedure, implanted devices, frequen...
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - April 29, 2013 Category: Neurology Authors: F. Andrew Kozel, Paul E. Croarkin, Kimberly S. Mapes Tags: Letters to the Editor Source Type: research

Eyelid Myokymia in an Older Subject After Repetitive Sessions of Anodal Transcranial Direct Current Stimulation
Non-invasive brain stimulation techniques have developed into useful tools to study brain functions, like motor learning , physiological changes of the brain like during healthy aging or pathological conditions (e.g., stroke, parkinson, tinnitus, among others) . Furthermore they are more and more applied and evaluated as therapeutic tools to treat neuropsychiatric diseases . The evolution of these techniques emphasizes the importance to report possible adverse effects. Here, we present a case with occurrence of monocular eyelid myokymia after repetitive application of anodal transcranial direct current stimulation (tDCS) to the motor cortex.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - November 5, 2012 Category: Neurology Authors: M. Wessel, M. Zimerman, J.E. Timmermann, F.C. Hummel Tags: Letters to the Editor Source Type: research

Mapping Early Changes of Cortical Motor Output after Subcortical Stroke: A Transcranial Magnetic Stimulation Study
Abstract: After acute stroke several changes in cortical excitability occur involving affected (AH) and unaffected hemisphere (UH) but whether they contribute to motor recovery is still controversial. We performed transcranial magnetic stimulation mapping of several upper limb muscles over the two hemispheres in thirteen patients at 4–12 days from subcortical stroke and after 1 month. The occurrence of mirror movements (MMs) on the healthy side during contraction of paretic muscles was measured. At baseline, cortical excitability parameters over the AH decreased in comparison with controls, while excitability over the UH...
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - July 2, 2012 Category: Neurology Authors: Raffaella Chieffo, Alberto Inuggi, Laura Straffi, Elisabetta Coppi, Javier Gonzalez-Rosa, Francesca Spagnolo, Antonella Poggi, Giancarlo Comi, Mauro Comola, Letizia Leocani Tags: Original Articles Source Type: research

Intermittent theta burst stimulation over ipsilesional primary motor cortex of subacute ischemic stroke patients: A pilot study
Conclusions: Repetitive sessions of iTBS1200 over ipsilesional M1 of subacute stroke patients are safe and the potential benefits encourage a larger trial to determine the efficacy in stroke patients. (ClinicalTrials.gov: NCT-01323881).
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - May 14, 2012 Category: Neurology Authors: Ya-Fang Hsu, Ying-Zu Huang, Yung-Yang Lin, Chih-Wei Tang, Kwong-Kum Liao, Po-Lei Lee, Yun-An Tsai, Hsien-Lin Cheng, Henrich Cheng, Chang-Ming Chern, I-Hui Lee Tags: Original Articles Source Type: research

Corticospinal excitability in patients with anoxic, traumatic, and non-traumatic diffuse brain injury
Conclusions: The present study demonstrated the impairment of the cortical inhibitory circuits in patients with brain injury of traumatic and non-traumatic aetiology. Moreover, the significant correlation was found between the amount of SICI and the severity of brain injury.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - April 19, 2012 Category: Neurology Authors: Natallia Lapitskaya, Sofie Kirial Moerk, Olivia Gosseries, Joergen Feldbaek Nielsen, Alain Maertens de Noordhout Tags: Original Articles Source Type: research