Filtered By:
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation
This page shows you your search results in order of date. This is page number 11.
Order by Relevance | Date
Total 298 results found since Jan 2013.
Transcranial direct current stimulation to treat aphasia: Longitudinal analysis of a randomized controlled trial
Post-stroke aphasia is a pervasive language disorder that affects communication and quality of life. Behavioral aphasia therapy is currently standard of care; however, in the chronic phase of recovery (>6 months post stroke), gains are often minimal. A number of studies have suggested that active transcranial direct current stimulation (A-tDCS) may improve treatment outcomes when coupled with behavioral aphasia therapy. However, many of these studies included small sample sizes or only single cases.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - September 29, 2018 Category: Neurology Authors: Julius Fridriksson, Alexandra Basilakos, Brielle C. Stark, Chris Rorden, Jordan Elm, Michelle Gottfried, Mark S. George, Souvik Sen, Leonardo Bonilha Source Type: research
Transcranial direct current stimulation reduces secondary white-matter degradation after stroke
Motor recovery during the first 3 to 6 months after stroke shows a striking dichotomy. For the upper-extremity, most patients recover ≈70% of the difference between their baseline Upper Extremity Fugl–Meyer (UE-FM) score and the maximum UE-FM score (proportional recovery, PROP) [1]. However, patients with severe initial impairment often show poor recovery (POOR). POOR patients do not sufficiently benefit from current treatment approaches and it would be important to identify new treatment targets that might enable better outcome for this group of patients.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - September 20, 2018 Category: Neurology Authors: C écile Magnin, Pierre Nicolo, Elena Pedrazzini, Anh Nguyen-Danse, Adrian G. Guggisberg Source Type: research
Response to ‘Cerebellum as a possible target for neuromodulation after stroke’
We appreciated Fran ça and colleagues' letter (‘Cerebellum as a possible target for neuromodulation after stroke’) in response to our systematic review on deep brain stimulation for stroke [1]. Their primary point – concerning the relevance of the cerebellum to post-stroke neuromodulation – is well taken, espe cially given the increasing recognition of the cerebellum as a critical hub in the widespread, distributed neuronal networks that subserve varied motor, cognitive, and emotional processes [2–4].
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - August 24, 2018 Category: Neurology Authors: Gavin J.B. Elias, Andres M. Lozano Source Type: research
Cerebellum as a possible target for neuromodulation after stroke
We read with great interest the article entitled “Deep brain stimulation for stroke: Current uses and future directions,” a systematic review of the current evidence for using neuromodulation as a rehabilitation tool after stroke [1]. This topic is of significant importance because stroke affects millions of people every year, leaving behind a large social burden in terms of medical costs. The rehabilitation techniques available to date often fail to restore a patient’s previous quality of life.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - April 23, 2018 Category: Neurology Authors: Carina Fran ça, Daniel Ciampi de Andrade, Manoel Jacobsen Teixeira, Rubens Gisbert Cury Source Type: research
Bi-hemispheric repetitive transcranial magnetic stimulation for upper limb motor recovery in chronic stroke: A feasibility study
With the emerging of a crucial role of non-primary and contralesional motor areas in the recovery of upper extremity (UE) after acute stroke [1,2], the ‘‘bimodal-balance recovery model“ has been proposed [3], with the hypothesis that the contribution of ipsi- and contralesional primary and secondary motor areas might vary according to the structural reserve of the ipsilesional corticospinal tract. This model opens to novel non-invasive brain stimulation approaches for improving the effects of neurorehabilitation, targeting bilateral, wide motor cortical regions rather than focusing on the ipsilateral or contralesional M1.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - March 15, 2018 Category: Neurology Authors: Raffaella Chieffo, Giuseppe Scopelliti, Mario Fichera, Roberto Santangelo, Simone Guerrieri, Abraham Zangen, Giancarlo Comi, Letizia Leocani Source Type: research
Variability of motor evoked potentials in stroke explained by corticospinal pathway integrity
Motor evoked potentials (MEPs) acquired using transcranial magnetic stimulation (TMS) are routinely used to index excitability of residual corticospinal tracts (CST) devoted to the paretic upper-limb in stroke. Unfortunately, MEPs suffer from considerable trial-to-trial variability [1]. Variability is attributed to several physiologic and methodological factors, such as TMS intensity or state of muscle activation [1]; but variability can also arise from the degree of damage to CST. No study to date has linked variability of MEPs to CST damage in stroke.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - March 9, 2018 Category: Neurology Authors: Kelsey A. Potter-Baker, Yin-Liang Lin, Andre G. Machado, Adriana B. Conforto, David A. Cunningham, Vishwanath Sankarasubramanian, Ken Sakaie, Ela B. Plow Source Type: research
Low Frequency repetitive Transcranial Magnetic Stimulation: Potential role in treatment of patients with hemispheric cerebellar strokes
Five years prior to TMS study, a 64 years old left-handed man with mild tremor-predominant Parkinson's disease that predominantly affected his right side experienced a large embolic left cerebellar infarct and subsequently required cerebellar hemispherectomy due to complications of cerebellar edema. He had no other evidence of brain lesions or stroke (Supplementary Figure). Patient was on Parkinson's medication Carbidopa/Levodopa 25 –100mg 3 times per day and denied having ON of OFF periods. Residual difficulties with coordination, speech, fine motor movements, spasticity and most prominently his balance led to the perma...
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - February 22, 2018 Category: Neurology Authors: Isabelle Buard, Jean M. Berliner, Benzi M. Kluger Source Type: research
Non-invasive vagus nerve stimulation reduces blood-brain barrier disruption in a rat model of ischemic stroke
Vagus nerve stimulation (VNS) significantly reduces infarct volume in rat models of cerebral ischemia, but the mechanism of this protective effect remains open.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - February 15, 2018 Category: Neurology Authors: Yirong Yang, Lisa Y. Yang, Lilla Orban, Darnell Cuylear, Jeffrey Thompson, Bruce Simon, Yi Yang Source Type: research
Decreased short-interval intracortical inhibition correlates with better pinch strength in patients with stroke and good motor recovery
Deeper short-interval intracortical inhibition (SICI), a marker of GABAA activity, correlates with better motor performance in patients with moderate to severe hand impairments in the chronic phase after stroke.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - February 2, 2018 Category: Neurology Authors: Karina Nocelo Ferreiro de Andrade, Adriana Bastos Conforto Source Type: research
