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Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation
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Total 298 results found since Jan 2013.
Safety of Noninvasive Brain Stimulation in Children and Adolescents
Noninvasive brain stimulation (NIBS) techniques such as transcranial magnetic stimulation (TMS) and transcranial current stimulation (tCS) have the potential to mitigate a variety of symptoms associated with neurological and psychiatric conditions, including stroke, cerebral palsy, autism, depression, and Tourette syndrome. While the safety of these modalities has been established in adults, there is a paucity of research assessing the safety of NIBS among children.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - October 27, 2014 Category: Neurology Authors: Chandramouli Krishnan, Luciana Santos, Mark D. Peterson, Margaret Ehinger Source Type: research
The outlook for non-invasive electrical brain stimulation
Over a decade since the initial establishment of modern transcranial direct current stimulation (tDCS), the field of transcranial electrical stimulation (tES) has blossomed to include a range of techniques (e.g., alternating current (tACS), random noise (tRNS), and pulsed current stimulation), and a diverse array of applications (e.g., depression, pain, tinnitus, stroke, and schizophrenia). At the cusp of even broader dissemination of tES as a tool for the treatment and rehabilitation of brain disorders, the study of brain function, and brain enhancement, it is incumbent to consolidate what have we learned and what remains to be addressed.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - October 23, 2014 Category: Neurology Authors: Marom Bikson, Dylan Edwards, Emily Kappenman Source Type: research
Immediate and Late Modulation of Interhemipheric Imbalance With Bilateral Transcranial Direct Current Stimulation in Acute Stroke
Significant changes in neurophysiological and clinical outcomes in chronic stroke had been reported after tDCS; but there is a paucity of data in acute stroke.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - October 9, 2014 Category: Neurology Authors: Vincenzo Di Lazzaro, Michele Dileone, Fioravante Capone, Giovanni Pellegrino, Federico Ranieri, Gabriella Musumeci, Lucia Florio, Giovanni Di Pino, Felipe Fregni Tags: Original Research Source Type: research
Electrical Stimulation of the Vagus Nerve Dermatome in the External Ear is Protective in Rat Cerebral Ischemia
Although cervical vagus nerve stimulation is effective for reducing infarct volume in rats, it is not feasible for acute human stroke as it requires surgical incision of the neck. We hypothesized that stimulation of the dermatome in the external ear innervated by the vagus nerve (auricular vagus nerve stimulation; aVNS) reduces infarct volume after transient focal ischemia in rats.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - September 25, 2014 Category: Neurology Authors: Ilknur Ay, Vitaly Napadow, Hakan Ay Tags: Original Research Source Type: research
Retrospective Safety and Efficacy of the DeepTMS in a variety of pathologies including refractory Major Depression, Bipolar Depression, Parkinsońs Disease, negative symptoms of Schizophrenia and Stroke in a clinical setting; an update on the post-Marketing experience in Chile
Repetitive transcranial magnetic stimulation (rTMS) has been proposed as add-on for the treatment of various pathologies, including refractory Major Depression (MD), Bipolar Depression (BD), Parkinsońs Disease (PD), negative symptoms of Schizophrenia (NS) and Stroke (ST). However, the effectiveness of the conventional rTMS in clinical settings is currently being debated. The novel Deep TMS H-coils can effectively stimulate deeper and larger brain regions than conventional rTMS coils, including the complete thickness of motor and prefrontal cortices, suggesting greater potential clinical efficacy.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - September 1, 2014 Category: Neurology Authors: Jimmy Stehberg, Francisco Torres, Esteban Villalón, Raúl Riquelme Tags: Poster Source Type: research
Val66Met BDNF Gene Polymorphism Influences Human Motor Cortex Plasticity in Acute Stroke
BDNF gene polymorphism impacts human motor cortex function and plasticity.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - August 22, 2014 Category: Neurology Authors: Vincenzo Di Lazzaro, Giovanni Pellegrino, Giovanni Di Pino, Marzia Corbetto, Federico Ranieri, Nicoletta Brunelli, Matteo Paolucci, Serena Bucossi, Maria C. Ventriglia, Peter Brown, Fioravante Capone Tags: Original Research Source Type: research
Broca's Area Damage is Necessary but not Sufficient to Induce After-effects of cathodal tDCS on the Unaffected Hemisphere in Post-stroke Aphasia
The inter-individual variability of behavioral effects after tDCS applied to the unaffected right hemisphere in stroke may be related to factors such as the lesion location.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - June 13, 2014 Category: Neurology Authors: C. Rosso, V. Perlbarg, R. Valabregue, C. Arbizu, S. Ferrieux, B. Alshawan, P. Vargas, A. Leger, C. Zavanone, J.C. Corvol, S. Meunier, S. Lehéricy, Y. Samson Tags: Transcranial Direct Current Stimulation (tDCS)/Transcranial Alternating Current Stimulation (tACS) Source Type: research
BDNF Polymorphism and Differential rTMS Effects on Motor Recovery of Stroke Patients
Conclusions: The findings suggest that the BDNF gene polymorphism negatively influences the effect of rTMS on the motor recovery of upper extremities in stroke patients.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - March 28, 2014 Category: Neurology Authors: Won Hyuk Chang, Oh Young Bang, Yong-Il Shin, Ahee Lee, Alvaro Pascual-Leone, Yun-Hee Kim Tags: Original Articles Source Type: research
Does cathodal transcranial direct current stimulation (ctDCS) plus standard upper limb rehabilitation augment motor recovery post acute stroke? – A pilot study
Interhemispheric balance (IHB) is disrupted after stroke. The contralesional hemisphere can exert an excessive inhibitory influence on the lesioned side, reducing activity in the damaged motor cortex and interfering with motor recovery. Non-invasive brain stimulation (NIBS) may ameliorate this imbalance. One form of NIBS is transcranial direct current stimulation (tDCS). tDCS can modulate cortical excitability in three ways: (1) excitatory (anodal) tDCS to the aff5cted hemisphere; (2) inhibitory (cathodal) tDCS (ctDCS) can dampen overactivity in the contralesional hemisphere; and (3) bihemispheric tDCS which produces a com...
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - March 1, 2014 Category: Neurology Authors: Jimena Garcia-Vega, Gillian Bowater, Belinda Rapperport, Christopher Lind, David Blacker, Souyma Ghosh, Gary Thickbroom, Ian Cooper, Barbara Singer Tags: Abstracts Presented at NYC Neuromodulation 2013 Source Type: research
Contralesional transcranial direct-current stimulation in a case of childhood stroke rehabilitation
Transcranial direct-current stimulation (tDCS) may modulate cortical excitability to enhance motor rehabilitation in adult stroke. Contralesional cathodal tDCS effects may reduce excessive interhemispheric inhibition from the non-lesioned hemisphere. Advanced imaging allows investigation of neurophysiological changes accompanying such interventions. tDCS has not been applied to the potentially more plastic brains of children, where stroke often leads to lifelong disability.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - March 1, 2014 Category: Neurology Authors: Patrick Ciechanski, Helen Carlson, Omar Damji, Colleen Lane, Adam Kirton Tags: Abstracts Presented at NYC Neuromodulation 2013 Source Type: research
Can enhancing left lateralization using transcranial direct current stimulation improve recovery from post-stroke aphasia?
One third of stroke victims suffer from aphasia, an acquired language disorder for which there are few effective medical treatments. Aphasia often does not resolve completely, resulting in substantial long-term disability. After a stroke that causes aphasia, the reorganization of language networks in the brain involves compensatory recruitment of brain tissue in the left hemisphere as well as potentially maladaptive recruitment of symmetric areas in the right hemisphere. One avenue for intervention might be to externally “left lateralize” the brain, enhancing activity of the left frontal lobe while inhibiting the right...
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - March 1, 2014 Category: Neurology Authors: Mackenzie Fama, Elizabeth Lacey, Alexa Desko, Lauren Taylor, Laura Hussey, Peter Turkeltaub Tags: Abstracts Presented at NYC Neuromodulation 2013 Source Type: research
Customization of transcranial Direct Current Stimulation for susceptible populations including at the extremes of age, obesity, and stroke
Transcranial direct current stimulation (tDCS) is a neuromodulatory technique that delivers low-intensity currents facilitating or inhibiting spontaneous neuronal activity. Such noninvasive electrotherapies have a number of advantages that have been exploited in clinical practice; in particular, tDCS dose is easily customized by varying electrode number, position, size, shape, and current. Recent developments in computational models have further customized dose to individual subjects and cases. Finite Element Method models developed from high-resolution MRI scans are among the tools available today. Designing and interpret...
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - March 1, 2014 Category: Neurology Authors: Dennis Truong, Preet Minhas, Albert Mokrejs, Marom Bikson Tags: Abstracts Presented at NYC Neuromodulation 2013 Source Type: research
