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Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation
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Total 298 results found since Jan 2013.
Motor cortex Transcranial Direct Current Stimulation (tDCS) improves acute stroke visuo-spatial neglect: A series of four case reports
Visuospatial neglect remains a relatively misunderstood complication of stroke. Up to 72% of right hemispheric strokes present neglect symptoms, and up to 75% of those patients still suffer at the 3-month mark [1]. This leads to marked increases in dependency, and lower functional outcomes [2].
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - November 30, 2017 Category: Neurology Authors: S. Bornheim, P. Maquet, J.L. Croisier, J.M. Crielaard, J.F. Kaux Source Type: research
Vagus nerve magnetic modulation facilitates dysphagia recovery in patients with stroke involving the brainstem - A proof of concept study
Stroke involving the brainstem (SBS) causes severe oropharyngeal dysphagia (OD). Research on the therapeutic efficacy of vagus nerve modulation (VNM) by using repetitive transcranial magnetic stimulation (rTMS) in SBS patients with OD has been limited thus far. We aimed to assess the effect of VNM by using rTMS in improving swallowing function after SBS.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - November 7, 2017 Category: Neurology Authors: Wang-Sheng Lin, Chen-Liang Chou, Miao-Hsiang Chang, Yuh-Mei Chung, Fu-Gong Lin, Po-Yi Tsai Source Type: research
Deep brain stimulation for stroke: Current uses and future directions
Survivors of stroke often experience significant disability and impaired quality of life related to ongoing maladaptive responses and persistent neurologic deficits. Novel therapeutic options are urgently needed to augment current approaches. One way to promote recovery and ameliorate symptoms may be to electrically stimulate the surviving brain. Various forms of brain stimulation have been investigated for use in stroke, including deep brain stimulation (DBS).
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - October 11, 2017 Category: Neurology Authors: Gavin J.B. Elias, Andrew A. Namasivayam, Andres M. Lozano Source Type: research
Changes in spectroscopic biomarkers after transcranial direct current stimulation in children with perinatal stroke
Perinatal stroke causes lifelong motor disability, affecting independence and quality of life. Non-invasive neuromodulation interventions such as transcranial direct current stimulation (tDCS) combined with intensive therapy may improve motor function in adult stroke hemiparesis but is under-explored in children. Measuring cortical metabolites with proton magnetic resonance spectroscopy (MRS) can inform cortical neurobiology in perinatal stroke but how these change with neuromodulation is yet to be explored.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - September 13, 2017 Category: Neurology Authors: Helen L. Carlson, Patrick Ciechanski, Ashley D. Harris, Frank P. MacMaster, Adam Kirton Source Type: research
Cranial nerve non-invasive neuromodulation improves gait and balance in stroke survivors: A pilot randomised controlled trial
Cranial nerve non-invasive neuromodulation (CN-NINM) is delivered using a Portable Neuromodulation Stimulation (PoNS ™) device that stimulates two cranial nerve nuclei (trigeminal and facial nerve nuclei) using electrodes embedded in a mouthpiece that rests on the tongue. Danilov and colleagues reported that prolonged and repetitive (20 minutes or more) tongue stimulation coupled with specific training of balanc e and gait can initiate long-lasting neuronal reorganization that can be measured in participants' behaviour [1].
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - September 1, 2017 Category: Neurology Authors: Mary P. Galea, L. Eduardo Cofr é Lizama, Andisheh Bastani, Maya G. Panisset, Fary Khan Source Type: research
BDNF Val66Met but not transcranial direct current stimulation affects motor learning after stroke
tDCS is a non-invasive neuromodulation technique that has been reported to improve motor skill learning after stroke. However, the contribution of tDCS to motor skill learning has only been investigated in a small number of studies. In addition, it is unclear if tDCS effects are mediated by activity-dependent BDNF release and dependent on timing of tDCS relative to training.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - July 13, 2017 Category: Neurology Authors: Rick van der Vliet, Gerard M. Ribbers, Yves Vandermeeren, Maarten A. Frens, Ruud W. Selles Source Type: research
The influence of sham repetitive transcranial magnetic stimulation on commonly collected TMS metrics in patients with chronic stroke
Repetitive transcranial magnetic stimulation (rTMS) is a non-invasive brain stimulation technique used in research to promote recovery for patients with chronic stroke by directly influencing neuronal activity. In research, sham-rTMS is often used to control for a placebo effect by mimicking auditory and somatosensory perception without actually stimulating the brain. Still, the influence of sham-rTMS on neuronal activity measured with single-pulse TMS has been given minimal attention. Therefore, our objective was to study the effect of sham-rTMS on TMS metrics and within-session reliability of these metrics from baseline ...
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - June 18, 2017 Category: Neurology Authors: David A. Cunningham, Jacqueline Cavendish, Vishwanath Sankarasubramanian, Kelsey A. Potter-Baker, Andre G. Machado, Ela B. Plow Source Type: research
The current level of evidence for using transcranial direct current stimulation (tDCS) to improve naming ability in post-stroke aphasia: a critical review
Transcranial Direct Current Stimulation (tDCS) is a non-invasive neuromodulation tool that can be used to manipulate cortical brain activity to induce measurable behavioral changes. Although there is growing evidence that tDCS combined with behavioural language therapy could boost language recovery in patients with post-stroke aphasia, there is great variability in patient characteristics, treatment protocols, and outcome measures in these studies that poses challenges for analyzing the evidence.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - June 18, 2017 Category: Neurology Authors: Mohammed F. ALHarbi, Susan Armijo-Olivo, Esther S. Kim Source Type: research
Optimal transcranial direct current stimulation polarity for enhancing motor recovery from severe post-stroke hemiparesis
Transcranial direct current stimulation (tDCS) has been shown to enhance outcomes of motor training for subjects with mild to moderate post-stroke motor deficit. To determine which tDCS configuration optimizes motor training in cases of severe post-stroke hemiparesis ( ≤ 19 out of 60, Fugl-Meyer Assessment (FMA) upper extremity motor score), this study randomized 26 subjects to 1 of 4 conditions: 1) “anodal” (anodal tDCS to the ipsilesional motor cortex); 2) “cathodal” (cathodal tDCS to the contralesional motor cortex); 3) “dual” (anodal tDCS to the ipsilesional motor cortex and cathodal tDCS to the contrales...
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - June 18, 2017 Category: Neurology Authors: Elizabeth Powell, Cheryl Carrico, Kenneth Chelette, Laurie Nichols, Lumy Sawaki Source Type: research
Transcranial direct current stimulation in primary progressive aphasia: Whom does it help?
Transcranial direct current stimulation (tDCS) has been shown to be a valuable adjunct to speech and language therapy, mainly in stroke rehabilitation and recently in primary progressive aphasia. An intriguing question that has not been addressed is whether different brain pathologies, atrophy patterns and symptoms associated with each variant of PPA have a differential impact on the effectiveness of electrical stimulation. We conducted a randomized sham-controlled, double-blind clinical trial using a within-subjects crossover design and we compared effects of tDCS coupled with oral and written naming therapy vs.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - June 18, 2017 Category: Neurology Authors: Kyrana Tsapkini, Kim Webster, Bronte N. Ficek, John Desmond, Chiadi Onyike, Brenda Rapp, Constantine E. Frangakis, Argye E. Hillis Source Type: research
Concurrent tDCS and Mirror Feedback has additive effects on M1 excitability
Mirror visual feedback (MVF) has been shown to aid recovery of movement after stroke, potentially by facilitating sensorimotor areas contralateral to the mirror-reflected hand. Similarly, non-invasive brain stimulation, such as transcranial direct stimulation (tDCS), can boost excitability of the motor cortex (M1) and aid recovery. Here we test if combining the two approaches concurrently will yield synergistic effects on M1 excitability compared to either approach alone. Four healthy subjects each performed 4 sessions of goal-oriented right finger movements in a virtual environment while receiving either MVF or veridical ...
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - June 18, 2017 Category: Neurology Authors: Ge “Paul” Chen, Mathew Yarossi, Seth Gordon, Kayla Gomes, Anna Rubakhina, Sergei Adamovich, Eugene Tunik Source Type: research
Seizure induced by repetitive transcranial magnetic stimulation for central pain: adapted guidelines for post-stroke patients
We report the following TMS-related seizure:
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - March 23, 2017 Category: Neurology Authors: M élanie Cogné, Cédric Gil-Jardiné, Pierre-Alain Joseph, Dominique Guehl, Bertrand Glize Source Type: research
TMS measures of motor cortex function after stroke: A meta-analysis
Transcranial magnetic stimulation (TMS) is commonly used to measure the effects of stroke on corticomotor excitability, intracortical function, and interhemispheric interactions. The interhemispheric inhibition model posits that recovery of motor function after stroke is linked to rebalancing of asymmetric interhemispheric inhibition and corticomotor excitability. This model forms the rationale for using neuromodulation techniques to suppress unaffected motor cortex excitability, and facilitate affected motor cortex excitability.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - March 23, 2017 Category: Neurology Authors: Michelle N. McDonnell, Cathy M. Stinear Source Type: research
