Filtered By:
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation
This page shows you your search results in order of relevance. This is page number 8.
Order by Relevance | Date
Total 298 results found since Jan 2013.
Bi-hemispheric repetitive transcranial magnetic stimulation for upper limb motor recovery in chronic stroke: A feasibility study
With the emerging of a crucial role of non-primary and contralesional motor areas in the recovery of upper extremity (UE) after acute stroke [1,2], the ‘‘bimodal-balance recovery model“ has been proposed [3], with the hypothesis that the contribution of ipsi- and contralesional primary and secondary motor areas might vary according to the structural reserve of the ipsilesional corticospinal tract. This model opens to novel non-invasive brain stimulation approaches for improving the effects of neurorehabilitation, targeting bilateral, wide motor cortical regions rather than focusing on the ipsilateral or contralesional M1.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - March 15, 2018 Category: Neurology Authors: Raffaella Chieffo, Giuseppe Scopelliti, Mario Fichera, Roberto Santangelo, Simone Guerrieri, Abraham Zangen, Giancarlo Comi, Letizia Leocani Source Type: research
Decreased short-interval intracortical inhibition correlates with better pinch strength in patients with stroke and good motor recovery
Deeper short-interval intracortical inhibition (SICI), a marker of GABAA activity, correlates with better motor performance in patients with moderate to severe hand impairments in the chronic phase after stroke.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - February 2, 2018 Category: Neurology Authors: Karina Nocelo Ferreiro de Andrade, Adriana Bastos Conforto Source Type: research
Motor cortex Transcranial Direct Current Stimulation (tDCS) improves acute stroke visuo-spatial neglect: A series of four case reports
Visuospatial neglect remains a relatively misunderstood complication of stroke. Up to 72% of right hemispheric strokes present neglect symptoms, and up to 75% of those patients still suffer at the 3-month mark [1]. This leads to marked increases in dependency, and lower functional outcomes [2].
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - November 30, 2017 Category: Neurology Authors: S. Bornheim, P. Maquet, J.L. Croisier, J.M. Crielaard, J.F. Kaux Source Type: research
Vagus nerve magnetic modulation facilitates dysphagia recovery in patients with stroke involving the brainstem - A proof of concept study
Stroke involving the brainstem (SBS) causes severe oropharyngeal dysphagia (OD). Research on the therapeutic efficacy of vagus nerve modulation (VNM) by using repetitive transcranial magnetic stimulation (rTMS) in SBS patients with OD has been limited thus far. We aimed to assess the effect of VNM by using rTMS in improving swallowing function after SBS.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - November 7, 2017 Category: Neurology Authors: Wang-Sheng Lin, Chen-Liang Chou, Miao-Hsiang Chang, Yuh-Mei Chung, Fu-Gong Lin, Po-Yi Tsai Source Type: research
Transcranial direct current stimulation reduces secondary white-matter degradation after stroke
Motor recovery during the first 3 to 6 months after stroke shows a striking dichotomy. For the upper-extremity, most patients recover ≈70% of the difference between their baseline Upper Extremity Fugl–Meyer (UE-FM) score and the maximum UE-FM score (proportional recovery, PROP) [1]. However, patients with severe initial impairment often show poor recovery (POOR). POOR patients do not sufficiently benefit from current treatment approaches and it would be important to identify new treatment targets that might enable better outcome for this group of patients.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - September 20, 2018 Category: Neurology Authors: C écile Magnin, Pierre Nicolo, Elena Pedrazzini, Anh Nguyen-Danse, Adrian G. Guggisberg Source Type: research
Stability of the Cardiovascular Response during Single-pulse TMS in Perinatal Stroke
Serious adverse events of syncope have been reported with single pulse transcranial magnetic stimulation (sp-TMS) in both healthy adults and adolescents post stroke [3, 5, 7-9]. Despite these reports, the physiological mechanisms leading to syncope during sp-TMS administration are not clearly understood. A syncopal event is classically identified by a sudden, large reduction in blood supply to neural tissue “cerebral hypoperfusion” to ultimately cause a loss of consciousness [2]. Common symptoms preceding syncope include lightheadedness, nausea, diaphoresis, and/or visual changes.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - November 20, 2018 Category: Neurology Authors: Manda L. Keller-Ross, Daniel P. Chantigian, Mo Chen, Tonya L. Rich, Chao-Ying Chen, Bernadette T. Gillick Source Type: research
Safety of cathodal transcranial direct current stimulation early after ischemic stroke
According to the hypothesis of interhemispheric inhibition, the unaffected motor cortex (M1UH) may excessively inhibit the motor cortex of the affected hemisphere (M1AH) in subjects with stroke leading to exaggeration of the contralateral upper limb paresis. TDCS can be used to either inhibit M1UH, excite M1AH, or both. Typically, anodal tDCS increases brain excitability and cathodal tDCS (ctDCS) has the opposite effect [1].
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - November 20, 2018 Category: Neurology Authors: Adriana B. Conforto, Larissa Servinsckins, Joselisa P.Q. de Paiva, Edson Amaro, Daniel G. dos Santos, Priscila Soares, Danielle S. Pires, Jed Meltzer, Ela B. Plow, Paloma F. de Freitas, Danielli S. Speciali, Priscila Lopes, Mario.F.P. Peres, Gisele S. Sil Source Type: research
Targeted brain stimulation to ameliorate vigilance in stroke: a combined tDCS-fMRI approach
A stroke can affect widely-distributed cortical/subcortical brain networks, causing behavioural deficits. Right frontoparietal networks are key in maintaining attentional focus over time, and right-hemispheric damage typically impairs vigilance.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - January 22, 2019 Category: Neurology Authors: E. Olgiati, I. Violante, L. Li, A. Faraj, T. Sinclair, J. Crow, R. Wise, P. Malhotra Source Type: research
Mapping contralesional motor cortex plasticity using robotic transcranial magnetic stimulation in children with perinatal stroke
Introduction: Children with perinatal stroke are disabled by hemiparetic cerebral palsy (HCP). Motor control of the affected limb often resides in the contralesional hemisphere with preserved ipsilateral connections. Intensive therapies improve hand function but predictors are unknown. Individualized maps of the motor cortex (M1) may provide insight but are poorly studied. We aimed to use robotic TMS to characterize contralesional motor maps and their association with hand function in HCP.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - January 22, 2019 Category: Neurology Authors: H. Kuo, E. Zewdie, A. Giuffre, A. Kirton Source Type: research
Insights from rodent stroke models
Ischemic injuries within the motor cortex results in functional deficits that profoundly impact activities of daily living in patients. Current rehabilitation protocols achieve only limited recovery of motor abilities. The brain reorganizes spontaneously after injury, and it is believed that appropriately boosting these neuroplastic processes may restore function via recruitment of spared areas and pathways. In this presentation, I will describe our recent work on novel experimental therapies for the recovery of motor function in a mouse model of focal stroke.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - January 22, 2019 Category: Neurology Authors: M. Caleo, C. Spalletti, C. Alia Source Type: research
Cerebellar low-intensity focused ultrasound stimulation can normalize asymmetrical hemispheric delta power after mouse ischemic stroke
Introduction: Functional asymmetry between lesioned and non-lesioned hemispheres after unilateral middle cerebral artery (MCA) stroke could be indicative of cerebral pathophysiology. We propose a low-intensity focused ultrasound (LIFU) can non-invasively stimulate the deep cerebellar nuclei and induce plasticity for reestablishing the balance between two cerebral hemispheres.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - January 22, 2019 Category: Neurology Authors: H. Baek, A. Sariev, S. Dong, S. Royer, H. Kim Source Type: research
Imaging brain plasticity in stroke patients with simultaneous paired associative stimulation PAS /fMRI
Introduction: Paired associative stimulation (PAS) is a non-invasive brain stimulation technique where two neural substrates are employed in a temporally coordinated manner in order to modulate cortico-motor excitability, typically within the motor cortex (M1). PAS effects are easiest to study in the motor system, although others have examined PAS with EEG and other techniques in non-motor areas. Here, we aimed to investigate brain connectivity changes during PAS treatment using interleaved PAS/functional magnetic resonance imaging (fMRI) in stroke patients compared to healthy controls.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - January 22, 2019 Category: Neurology Authors: X. Li, M. George, W. Feng, T. Brown, M. Woodbury, S. Kautz Source Type: research
Effect of different frequencies in repetitive transcranial magnetic stimulation for the patients with post-stroke motor aphasia
In this study, we applied low and high frequency rTMS targeting the bilateral hemispheres. The purpose of this study is to evaluate the efficacy of two types of rTMS for post-stroke motor aphasia.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - January 22, 2019 Category: Neurology Authors: R. Awa, H. Tokimura, H. Yamanaka, Y. Tokimura, S. Etoh, K. Todoroki, K. Takasaki, M. Atsuchi, M. Atsuchi Source Type: research
The use of rTMS to augment walking recovery after stroke
The goal of non-invasive brain stimulation to directly target brain circuitry to increase neural plasticity and improve coordinated activation of muscles after walking rehabilitation. Neuromodulation using rTMS has been incredibly successful in treating depression and has had some success with improving upper extremity (UE) motor control after stroke through either exciting (E-rTMS) ipsilesional or inhibiting (I-rTMS) contralesional activity. However, similar successes with rTMS for walking have not been achieved in the very few attempts made to date.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - January 22, 2019 Category: Neurology Authors: M. Bowden Source Type: research
A multimodal approach to understand upper-limb motor impairment after stroke in subacute and chronic phases
Purpose: Accumulated evidence supports motor evoked potential (MEP) status and neuroimaging measures of corticospinal tract (CST) integrity as useful biomarkers for understanding upper-limb motor outcome. Our aim was to determine which biomarkers among electrophysiological and MRI variables can accurately explain the motor impairment in subacute and chronic stroke patients.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - January 22, 2019 Category: Neurology Authors: C. Kemlin, E. Moulton, M. Houot, S. Medhi, J. Lamy, C. Rosso Source Type: research
