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Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation
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Total 298 results found since Jan 2013.
Center of Pressure Speed Changes with tDCS Versus GVS in Patients with Lateropulsion after Stroke
We offer this letter to spark discussion about potential transcranial methods to augment rehabilitation to ameliorate lateropulsion after stroke. Patients with lateropulsion after stroke, also known as ‘pusher syndrome,’ actively push themselves to the weak side and resist passive correction of the posture to the vertical upright [1]. Various lesion sites along pathways which formulate subjective perceptions of verticality have been implicated in lateropulsion. Transcranial direct current stim ulation (tDCS) or galvanic vestibular stimulation (GVS) over parts of the impaired pathways may change seated center of pressur...
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - June 20, 2016 Category: Neurology Authors: Suzanne Babyar, Taiza Santos-Pontelli, Tenysson Will-Lemos, Suleimy Mazin, Marom Bikson, Dennis Q. Truong, Dylan Edwards, Michael Reding Tags: Letter to the Editor Source Type: research
The Effects of 10-Hz Repetitive Transcranial Magnetic Stimulation on Depression in Chronic Stroke Patients
• 10-Hz rTMS on the left DLPFC is effective in managing post-stroke depression.• The effect for managing depression was sustained at least 1 month.• We showed the potential utility of rTMS for managing depression in stroke patients
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - October 17, 2016 Category: Neurology Authors: Seo Young Gu, Min Cheol Chang Source Type: research
Targeting interhemispheric inhibition with neuromodulation to enhance stroke rehabilitation
Interhemispheric inhibition in the brain plays a dynamic role in the production of voluntary unimanual actions. In stroke, the interhemispheric imbalance model predicts the presence of asymmetry in interhemispheric inhibition, with excessive inhibition from the contralesional hemisphere limiting maximal recovery. Stimulation methods to reduce this asymmetry in the brain may be promising as a stroke therapy, however determining how to best measure and modulate interhemispheric inhibition and who is likely to benefit, remain important questions.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - January 12, 2017 Category: Neurology Authors: L.J. Boddington, J.N.J. Reynolds Source Type: research
Effects of rTMS based on brain activation during language performance in stroke patients with non-fluent Aphasia (Pilot Study)
Introduction: In post-stroke aphasia rehabilitation, repetitive transcranial stimulation (rTMS) aimed to reinforce the activity of the brain regions in the left hemisphere. Most conventional rTMS studies employed an inhibitory low frequency protocol for the contralesional homologs of Broca's area. In the present pilot study, we performed functional near-infrared spectroscopy (fNIRS) prior to excitatory rTMS treatment for selection of the most appropriate application of stimulation. The purpose of this study is to assess the safety and clinical efficacy of high frequency repetitive transcranial magnetic stimulation based on...
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - February 15, 2017 Category: Neurology Authors: B.S. Kwon, N.-J. Paik, W.-S. Kim, J.-H. Park, S. Kwon Source Type: research
Effect of ipsilesional anodal tDCS with contralesional low-frequency rTMS for post-stroke motor impairment
Introduction: Noninvasive brain stimulation using the repetitive transcranial magnetic stimulation (rTMS) or the transcranial direct current stimulation (tDCS) were recently adopted for modulating motor function of stroke patients. We investigated the effect of simultaneous dual-mode stimulation applying low-frequency rTMS (LF-rTMS) over the contralesional primary motor cortex (M1) and anodal tDCS over the ipsilesional M1 compared with single LF-rTMS over the contralesional M1 for motor recovery in subacute stroke patients.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - February 15, 2017 Category: Neurology Authors: Y.-H. Kim, E. Park, J.-S. Lee, W.-H. Chang, A. Lee Source Type: research
Distinction of functional corticomuscular coupling in synkinetic and separate movement following stroke
Motor dysfunction is a major consequence of stroke and it is generally believed that the loss of motor ability is caused by the impairments in neural network that control movement. The aim of our research is to explore the functional connection between the motor cortex and the contralateral muscles in stroke patients at both synkinetic and separate movement stages, and further investigate the relationship between the functional corticomuscular coupling (FCMC) and the clinical assessment scale (CAS).
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - February 15, 2017 Category: Neurology Authors: X.L. Chen, P. Xie, Y.Y. Zhang, L.X. Liu, Y.H. Du Source Type: research
Non-invasive brain stimulation to enhance stroke recovery – towards patient-tailored strategies
Stroke is the leading cause of serious long-term disability with growing impact on actual and future health economy. The resulting deficits of a stroke, e.g., of the upper extremity or language, have great impact on activities of daily life, social as well as professional.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - February 15, 2017 Category: Neurology Authors: F.C. Hummel Source Type: research
Effects of bihemispheric tDCS combined with radial nerve stimulation in acute stroke patients
Introduction: Transcranial direct current stimulation (tDCS) may change the excitability of the central nervous system and contribute to motor recovery of patients with acute stroke. The functional benefit may increase with the combination of tDCS with manoeuvres facilitating motor output. We have evaluated the effects of tDCS coupled with radial nerve stimulation in the acute phase after stroke.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - February 15, 2017 Category: Neurology Authors: S. Yag üe, M. Veciana, J. Pedro, A. Martínez-Yélamos, H. Kumru, P. Cardona, B. Lara, B. García, J. Montero, J. Valls-Sole Source Type: research
Variability in response to non-invasive brain stimulation in stroke patients
Introduction: It may be possible to simplify determinants of variability into two groups: intrinsic and extrinsic. Intrinsic variability may relate to factors that are impossible to modify, such as age, gender, and genetics. Extrinsic variability is potentially controllable and includes factors such as detection of the motor hotspot, stability of holding coil, the attention level of subjects in a long experiment, etc. In case of stroke patients, two factors may be added to this extrinsic variability, such as anatomical regions and the time from stroke onset.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - February 15, 2017 Category: Neurology Authors: N.S. Ward Source Type: research
5Hz repetitive transcranial magnetic stimulation (rTMS)-effects on cortical excitability and speech and swallowing functions in stroke patients
This study aimed to further study the effects of 5Hz rTMS on cortical excitability and speech and swallowing functions.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - February 15, 2017 Category: Neurology Authors: I.K.Y. Cheng, E.M.L. Yiu, L.S.W. Li, K.M.Y. Chiu, C.S. Wong, K.M.K. Chan Source Type: research
Sequential Theta burst stimulation changes language function after stroke - Preliminary analysis in Chinese survivors
Introduction: Theta burst stimulation (TBS) is a patterned repetitive transcranial magnetic stimulation (rTMS) protocol with relatively short stimulation period and strong power. Controlled trial of sequential TBS in post-stroke aphasia has been scarce. We aimed to investigate the potential therapeutic effect of consecutive suppressive-facilitatory TBS on language outcome after stroke.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - February 15, 2017 Category: Neurology Authors: W. He, K. Lee, T. Leung, H. Leung, Q. Zhang, L. Wong Source Type: research
Does the presence of a TMS-evoked MEP predict walking speeds in individuals with chronic stroke?
Background: Motor evoked potentials (MEPs), elicited with single pulse transcranial magnetic stimulation (TMS), provide a quantification of corticomotor excitability and is used to preditc motor recovery. It is unknown whether the presence or absence of lower limb MEPs are predictors of gait speed post stroke. The main purpose of this study was to determine whether the presence of a MEP is associated with recovery of gait speed and walking reserve in individuals with chronic stroke.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - February 15, 2017 Category: Neurology Authors: S. Madhavan, M. Yerrapothu, A. Williams, A. Gradowska Source Type: research
TMS measures of motor cortex function after stroke: A meta-analysis
Transcranial magnetic stimulation (TMS) is commonly used to measure the effects of stroke on corticomotor excitability, intracortical function, and interhemispheric interactions. The interhemispheric inhibition model posits that recovery of motor function after stroke is linked to rebalancing of asymmetric interhemispheric inhibition and corticomotor excitability. This model forms the rationale for using neuromodulation techniques to suppress unaffected motor cortex excitability, and facilitate affected motor cortex excitability.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - March 23, 2017 Category: Neurology Authors: Michelle N. McDonnell, Cathy M. Stinear Source Type: research
Optimal transcranial direct current stimulation polarity for enhancing motor recovery from severe post-stroke hemiparesis
Transcranial direct current stimulation (tDCS) has been shown to enhance outcomes of motor training for subjects with mild to moderate post-stroke motor deficit. To determine which tDCS configuration optimizes motor training in cases of severe post-stroke hemiparesis ( ≤ 19 out of 60, Fugl-Meyer Assessment (FMA) upper extremity motor score), this study randomized 26 subjects to 1 of 4 conditions: 1) “anodal” (anodal tDCS to the ipsilesional motor cortex); 2) “cathodal” (cathodal tDCS to the contralesional motor cortex); 3) “dual” (anodal tDCS to the ipsilesional motor cortex and cathodal tDCS to the contrales...
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - June 18, 2017 Category: Neurology Authors: Elizabeth Powell, Cheryl Carrico, Kenneth Chelette, Laurie Nichols, Lumy Sawaki Source Type: research
Deep brain stimulation for stroke: Current uses and future directions
Survivors of stroke often experience significant disability and impaired quality of life related to ongoing maladaptive responses and persistent neurologic deficits. Novel therapeutic options are urgently needed to augment current approaches. One way to promote recovery and ameliorate symptoms may be to electrically stimulate the surviving brain. Various forms of brain stimulation have been investigated for use in stroke, including deep brain stimulation (DBS).
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - October 11, 2017 Category: Neurology Authors: Gavin J.B. Elias, Andrew A. Namasivayam, Andres M. Lozano Source Type: research
