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Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation
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Total 298 results found since Jan 2013.
Diffusion tensor imaging evaluation of neural network development in patients undergoing therapeutic repetitive transcranial magnetic stimulation following stroke
Introduction: Motor function recovery in patients with stroke is considered to be largely due to plastic changes in the cerebral cortex. In the present study, we investigated plastic changes in cerebral white matter structures following a 15-day rehabilitation period using generalized fractional anisotropy (GFA) values.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - February 15, 2017 Category: Neurology Authors: N. Yamada, R. Ueda, W. Kakuda, R. Momosaki, T. Kondo, T. Hara, A. Senoo, M. Abo Source Type: research
The role of the cerebellum on motor recovery following stroke
The cerebellum is a critical structure for motor control and learning. The cerebellum does not have direct connections to lower motor neurons. However, its extensive connections to distribute motor regions and its role on motor control make it a structure that plays an important role in motor function following cerebral lesions. In addition, due to the cerebellar involvement in motor learning it plays an important when learning how to compensate for motor deficits arising from stroke. Indeed, previous studies suggested that restoration of cerebellar activation following diaschisis is associated with overall recovery follow...
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - February 15, 2017 Category: Neurology Authors: P. Celnik Source Type: research
Intervention induced intra-cortical plasticity in hemiparetic children with perinatal stroke
Introduction: Clinical trials are demonstrating efficacy of intensive hand training and/or brain stimulation therapies in improving hand function in hemiparetic children with perinatal stroke. However, high variability in individual responsiveness exists and the underlying neuroplasticity mechanisms responsible are virtually unknown. The neurophysiology of motor cortex (M1) and how it changes with therapeutic neuromodulation may provide valuable biomarkers for advancing treatments, patient selection, and personalized medicine.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - February 15, 2017 Category: Neurology Authors: H.C. Kuo, E. Zewdie, P. Ciechanski, A. Kirton Source Type: research
Functional network reorganization by dual-mode noninvasive brain stimulation in stroke patients
Introduction: The effect of simultaneous dual-mode stimulation using repetitive transcranial magnetic stimulation (rTMS) and transcranial direct current stimulation (tDCS) over the bilateral primary motor cortices (M1) in functional motor network was investigated as compared to single stimulation using rTMS alone over the ipsilesional M1 in subacute stroke patients.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - February 15, 2017 Category: Neurology Authors: J. Lee, E. Park, A. Lee, W.H. Chang, D.S. Kim, Y.H. Kim Source Type: research
Effects of prefrontal transcranial direct current stimulation on language production in post-stroke aphasia
A successful interplay between prefrontal and domain-specific language areas has been shown to be crucial for language processing. Non-invasive brain stimulation is increasingly being used as a promising therapeutic tool for neurological diseases. The aim of the present study is to investigate the effects of transcranial direct current stimulation (tDCS) of the prefrontal cortex (PFC) on language production in chronic post-stroke aphasic patients.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - February 15, 2017 Category: Neurology Authors: M.I. Pestalozzi, M. Di Pietro, G. Gaytanidis, L. Chouiter, L. Spierer, A. Schnider, J.M. Annoni, L.B. Jost Source Type: research
Neurorehabilitation treatment of dysphagia after-stroke with transcranial direct current stimulation: A clinical case
Introduction: Transcranial Direct Current Stimulation is a non-invasive neuromodulation technique that has been presented in the last years as a potential adjuvant neurorehabilitation tool that has shown positive effects in a variety of motor diseases. Hence, in our study, we tested whereas Transcranial Direct Current Stimulation applied together with swallowing training could benefit a resistant-treatment patient with dysphagia after stroke.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - February 15, 2017 Category: Neurology Authors: A. S ánchez-Kuhn, Y. Medina, M. Pérez-García, M. Martínez-Sola, P. De Haro, P. Flores, F. Sánchez-Santed Source Type: research
Decoding post-stroke motor function from structural brain images
Introduction: The ability to predict outcome after stroke is clinically important for planning treatment and for stratification in restorative clinical trials. In relation to upper limb function, the proportional recovery rule tells us that initial severity is the best predictor of long-term outcome, with most patients regaining about 70% of their lost motor function by 3 months. This rule works well for those presenting with mild to moderate upper limb impairment but in those with initially severe impairment about 50% fail to experience proportional recovery.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - February 15, 2017 Category: Neurology Authors: N.S. Ward Source Type: research
The efficacy of selective transcranial magnetic stimulation with functional near-infrared spectroscopy and intensive speech therapy on individuals with post-stroke aphasia
Introduction: To examine the efficacy of selective repetitive transcranial magnetic stimulation (rTMS) therapy guided by functional near-infrared spectroscopy (fNIRS) combined with intensive speech therapy(ST) on post-stroke patients with aphasia, and right hemisphere high-frequency rTMS combined with intensive ST on patients who were right hemisphere-activated in a language task.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - February 15, 2017 Category: Neurology Authors: T. Hara, M. Abo, K. Kakita Source Type: research
The influence of sham repetitive transcranial magnetic stimulation on commonly collected TMS metrics in patients with chronic stroke
Repetitive transcranial magnetic stimulation (rTMS) is a non-invasive brain stimulation technique used in research to promote recovery for patients with chronic stroke by directly influencing neuronal activity. In research, sham-rTMS is often used to control for a placebo effect by mimicking auditory and somatosensory perception without actually stimulating the brain. Still, the influence of sham-rTMS on neuronal activity measured with single-pulse TMS has been given minimal attention. Therefore, our objective was to study the effect of sham-rTMS on TMS metrics and within-session reliability of these metrics from baseline ...
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - June 18, 2017 Category: Neurology Authors: David A. Cunningham, Jacqueline Cavendish, Vishwanath Sankarasubramanian, Kelsey A. Potter-Baker, Andre G. Machado, Ela B. Plow Source Type: research
The current level of evidence for using transcranial direct current stimulation (tDCS) to improve naming ability in post-stroke aphasia: a critical review
Transcranial Direct Current Stimulation (tDCS) is a non-invasive neuromodulation tool that can be used to manipulate cortical brain activity to induce measurable behavioral changes. Although there is growing evidence that tDCS combined with behavioural language therapy could boost language recovery in patients with post-stroke aphasia, there is great variability in patient characteristics, treatment protocols, and outcome measures in these studies that poses challenges for analyzing the evidence.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - June 18, 2017 Category: Neurology Authors: Mohammed F. ALHarbi, Susan Armijo-Olivo, Esther S. Kim Source Type: research
BDNF Val66Met but not transcranial direct current stimulation affects motor learning after stroke
tDCS is a non-invasive neuromodulation technique that has been reported to improve motor skill learning after stroke. However, the contribution of tDCS to motor skill learning has only been investigated in a small number of studies. In addition, it is unclear if tDCS effects are mediated by activity-dependent BDNF release and dependent on timing of tDCS relative to training.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - July 13, 2017 Category: Neurology Authors: Rick van der Vliet, Gerard M. Ribbers, Yves Vandermeeren, Maarten A. Frens, Ruud W. Selles Source Type: research
Vagus nerve magnetic modulation facilitates dysphagia recovery in patients with stroke involving the brainstem - A proof of concept study
Stroke involving the brainstem (SBS) causes severe oropharyngeal dysphagia (OD). Research on the therapeutic efficacy of vagus nerve modulation (VNM) by using repetitive transcranial magnetic stimulation (rTMS) in SBS patients with OD has been limited thus far. We aimed to assess the effect of VNM by using rTMS in improving swallowing function after SBS.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - November 7, 2017 Category: Neurology Authors: Wang-Sheng Lin, Chen-Liang Chou, Miao-Hsiang Chang, Yuh-Mei Chung, Fu-Gong Lin, Po-Yi Tsai Source Type: research
Motor cortex Transcranial Direct Current Stimulation (tDCS) improves acute stroke visuo-spatial neglect: A series of four case reports
Visuospatial neglect remains a relatively misunderstood complication of stroke. Up to 72% of right hemispheric strokes present neglect symptoms, and up to 75% of those patients still suffer at the 3-month mark [1]. This leads to marked increases in dependency, and lower functional outcomes [2].
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - November 30, 2017 Category: Neurology Authors: S. Bornheim, P. Maquet, J.L. Croisier, J.M. Crielaard, J.F. Kaux Source Type: research
Decreased short-interval intracortical inhibition correlates with better pinch strength in patients with stroke and good motor recovery
Deeper short-interval intracortical inhibition (SICI), a marker of GABAA activity, correlates with better motor performance in patients with moderate to severe hand impairments in the chronic phase after stroke.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - February 2, 2018 Category: Neurology Authors: Karina Nocelo Ferreiro de Andrade, Adriana Bastos Conforto Source Type: research
Bi-hemispheric repetitive transcranial magnetic stimulation for upper limb motor recovery in chronic stroke: A feasibility study
With the emerging of a crucial role of non-primary and contralesional motor areas in the recovery of upper extremity (UE) after acute stroke [1,2], the ‘‘bimodal-balance recovery model“ has been proposed [3], with the hypothesis that the contribution of ipsi- and contralesional primary and secondary motor areas might vary according to the structural reserve of the ipsilesional corticospinal tract. This model opens to novel non-invasive brain stimulation approaches for improving the effects of neurorehabilitation, targeting bilateral, wide motor cortical regions rather than focusing on the ipsilateral or contralesional M1.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - March 15, 2018 Category: Neurology Authors: Raffaella Chieffo, Giuseppe Scopelliti, Mario Fichera, Roberto Santangelo, Simone Guerrieri, Abraham Zangen, Giancarlo Comi, Letizia Leocani Source Type: research
