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Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation
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Total 298 results found since Jan 2013.
Center of Pressure Speed Changes with tDCS Versus GVS in Patients with Lateropulsion after Stroke
Dear Editor:
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - June 20, 2016 Category: Neurology Authors: Suzanne Babyar, Taiza Santos-Pontelli, Tenysson Lemos, Suleimy Mazin, Marom Bikson, Dennis Q. Truong, Dylan Edwards, Michael Reding Source Type: research
Does Transcranial Direct Current Stimulation Actually Deliver DC Stimulation: Response to Letter to the Editor
Transcranial direct current stimulation (tDCS) is a common form of transcranial electric stimulation (tES). It delivers constant, low intensity currents to the brain through spongy type electrodes on the scalp [1]. tDCS has been explored for producing behavioral changes and cognitive enhancement in healthy individuals [2]. Furthermore, tDCS may be helpful in attenuating symptoms of neurological disorders such as Parkinson's disease, Alzheimer's disease, schizophrenia, and stroke [3,4]. There are currently no FDA approved indications for its clinical use.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - June 2, 2016 Category: Neurology Authors: Yousef Salimpour, Kelly A. Mills, Zhikui Wei, Phan Q. Duy, William S. Anderson Tags: Letter to the Editor Source Type: research
The Proof is in the Pudding: Does tDCS Actually Deliver DC Stimulation?
Transcranial direct current stimulation (tDCS) is an increasingly used investigational modality for a variety of disease conditions worldwide, including stroke [1]. It is relatively easy to use, low-cost, and has a reasonable safety profile with currents up to 2 mA. The effect of tDCS on membrane potentials has been demonstrated in vitro [2] as well as in vivo through simulation of tDCS-generated electric fields [3]. Real-time monitoring of applied voltage and injected current in tDCS application is offered as an inbuilt feature of many tDCS devices and can be achieved with a simple data acquisition setup.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - May 10, 2016 Category: Neurology Authors: Pratik Y. Chhatbar, James R. Sawers, Wuwei Feng Tags: Letter to the Editor Source Type: research
Short Circuit in Deep Brain Stimulation for Parkinson's Disease Mimicking Stroke
To the Editor:
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - August 20, 2016 Category: Neurology Authors: Niels Allert, Marta Reyes Santana, Hans Karbe Source Type: research
Antidepressant Effect of Low-Frequency Right-Sided rTMS in Two Patients with Left Frontal Stroke
Dear Editor:
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - October 5, 2016 Category: Neurology Authors: Kevin A. Caulfield, Margo H. Bernstein, Adam P. Stern, Alvaro Pascual-Leone, Daniel Z. Press, Michael D. Fox Source Type: research
Local Immediate Versus Long-Range Delayed Changes in Functional Connectivity Following rTMS on the Visual Attention Network
• Offline inhibitory rTMS over the left intraparietal sulcus has a local, immediate and brief impact on the network integrity to functionally connected cortical regions in the dorsal attention network• Those individuals with more disruptions in local functional connectivity are most impaired on sustained visual attention tasks, which dovetails with the hypothesized role of interhemispheric balance for bilateral visual sustained attention• rTMS over left intraparietal sulcus creates remote and delayed increases in interregional functional connectivity in distal brain sites, which may have implications for models of co...
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - October 18, 2016 Category: Neurology Authors: Lorella Battelli, Emily D. Grossman, Ela B. Plow Source Type: research
Potential beneficial effects of high frequency rTMS to enhance visual function in bilateral visual cortex stroke: Case report
Transcranial magnetic stimulation (TMS) is a non-invasive brain stimulation (NIBS) technique in which an electrical current flows through a coil, generating a magnetic field, which in turn induces an electric field within the targeted cortical neurons, activating them and their related neuronal networks evoking responses in motor and non motor pathways, as phosphenes when applied over visual cortex [1]; delivering repetitive TMS pulses (rTMS) can increase (high frequency) or reduce (low frequency) cortical excitability, and when applied in daily sessions, rTMS can achieve long lasting effects by inducing synaptic plasticity [2,3].
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - November 22, 2016 Category: Neurology Authors: Jos é L. Guerrero Solano, Elena Molina Pacheco, Giovana Femat Roldan, Julio I. Prieto Montalvo, Juan F. Gongora Rivera Source Type: research
Considerations for Research Treatment of Aphasia Combining Neuromodulation and Speech-Language Intervention
Aphasia, commonly defined as impairment or loss of language functions, is a frequent and often chronic consequence of left-hemispheric stroke. The effects of aphasia on patient independence and quality of life are often lifelong. Although beneficial in some cases, the effectiveness of behavioral speech-language therapy is often limited. Therefore, in these last decades, new treatment designs combining speech-language therapy and noninvasive brain stimulation techniques such as transcranial direct current stimulation (tDCS) have been developed with the goal of maximizing the recovery process.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - December 31, 2016 Category: Neurology Authors: Elizabeth E. Galletta, Adam Buchwald, Jessica Richardson, Julius Fridriksson, Roy Hamilton, Peter Turkeltaub, Paola Marangolo Source Type: research
Hemispace Matters in Normal Individuals: Effects of Gaze and Hand Location on Corticospinal Excitability
Effects of hemispace on perception and action are commonly observed in stroke survivors. In the hemispatial neglect syndrome, for example, patients fail to reliably perceive, orient to or initiate action towards stimuli in contralesional space. Stimulus location may also affect higher-level cognitive processes like language, however. Effects of hemispace on perception and action have not been extensively explored in normal individuals. Using single-pulse transcranial magnetic stimulation (TMS) over primary motor cortex, the present study examined hemispace effects on motor evoked potentials (MEPs).
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - December 31, 2016 Category: Neurology Authors: Matthieu M. de Wit, Olufunsho K. Faseyitan, H. Branch Coslett Source Type: research
Enhancing low-frequency oscillations using on-demand direct-current stimulation improves motor function after stroke
Introduction: 50% of strokesurvivors continue to have chronic motor deficits when tracked up to 5 years later, with limited therapeutic options available. One novel approach for treating these patients is to design a chronic neural-interface that could deliver stimulation optimally timed to improve the neural circuits associated with skilled actions.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - February 15, 2017 Category: Neurology Authors: D.S. Ramanathan, L. Guo, T. Gulati, S.J. Won, G. Davidson, A. Hishinuma, K. Ganguly Source Type: research
Left unilateral ultrabrief ECT in a patient with Cerebral Aneurysms and right side stoke
Introduction: To evaluate safety and efficacy of a left unilateral ultrabrief (LU-UB) ECT treatment for patient with 2 repaired brain aneurysms and right side encephalomalacia secondary to right side ischemic stroke.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - February 15, 2017 Category: Neurology Authors: A.Z. Elmaadawi, S. Mashaly, S. Nasr Source Type: research
MRI-compatible bilateral tDCS in rats: effects on functional connectivity in the sensorimotor network
Transcranial direct current stimulation (tDCS) is a noninvasive brain stimulation technique that influences neuronal excitability through subthreshold direct current. Bilateral tDCS, with anodal and cathodal electrodes positioned bihemispherically over homologous regions, has shown therapeutic promise in post-stroke recovery. However, its influence on underlying brain structure and function remains unclear. Therefore, our goal was to establish an MRI-compatible rat tDCS model to investigate the effects of bilateral stimulation on brain network measures.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - February 15, 2017 Category: Neurology Authors: D.J. Ardesch, J. Boonzaier, C.L. van Heiningen, G. van Vliet, S.F. Neggers, A. van der Toorn, R.M. Dijkhuizen Source Type: research
Transcranial Direct Current Stimulation and neural reorganisation after aphasia treatment
This study aims to investigate the effect of LH anodal tDCS on the neural reorganisation of language in the context of aphasia treatment.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - February 15, 2017 Category: Neurology Authors: R.M.A. Blom-Smink, K. Spielmann, C.P.M. Orellana, M. Smits, J. Crinion, W.M.E. van de Sandt-Koenderman, G.M. Ribbers Source Type: research
The role of inhibition in motor performance and learning
Introduction: Understanding the neurophysiological underpinnings of motor plasticity is of prime importance, not least for developing novel therapeutic approaches after a stroke. There is substantial evidence from animal models to support the hypothesis that modulation of GABA, the major inhibitory neurotransmitter, is a necessary step in motor learning. However, until recently it has been difficult to assess whether GABA is necessary for plasticity in vivo in humans.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - February 15, 2017 Category: Neurology Authors: J. Kolasinski, A. Johnstone, V. Bachtiar, C.J. Stagg Source Type: research
Magnetic focusing by magnetic shielding for Non-Invasive Brain Stimulation
Instruction: Transcranial magnetic stimulation (TMS) is one of the most widely used methods for brain stimulation. It is utilized in diagnosis and treatment for many neural diseases, such as neuropathic pain and loss of function caused by stroke. Current commercial TMS stimulators cannot provide well targeted stimulation. Due to fast field divergence, the effective distance in TMS is limited to around 1.5 cm. A breakthrough is needed to achieve non-invasive, focused brain stimulation.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - February 15, 2017 Category: Neurology Authors: Q. Meng, M. Cherry, X. Du, H. Lu, E. Hong, Y. Yang, F.-S. Choa Source Type: research
