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Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation
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Total 298 results found since Jan 2013.
Abstract #7: HD-tDCS to contralesional hemisphere to enhance treatment outcomes in persons with stroke-induced aphasia
Background: Chronic aphasia, or language difficulty persisting beyond one year post-stroke, affects over 2.5 million individuals in the United States. Treatment response varies and language abilities are rarely restored. Intact, connected ipsilesional language areas and improved interhemispheric balance following stroke are consistent predictors of recovery. A promising approach to target these brain dynamics is using high-definition transcranial direct current stimulation (HD-tDCS) to deliver focal cathodal current to right frontal areas in the contralesional hemisphere, combined with efficacious behavioral treatment that...
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - January 22, 2019 Category: Neurology Authors: J.D. Richardson, S.G.H. Dalton, J.F. Cavanagh, C. Shultz, J. Adams Source Type: research
Abstract #4: Pipeline Verification for the Identification of Noninvasive Neuromodulation Targets for Pediatric Stroke Rehabilitation
Introduction: Ischemic perinatal stroke affects as many as 1 in 2,300 live births and may result in lifelong burden of care. Thus, better rehabilitation techniques are indicated to improve quality of life for individuals and families. Implementing interventions early in life can harness neuroplastic potential to promote recovery. Transcranial magnetic stimulation (TMS) and transcranial direct current stimulation (tDCS) have shown promise as noninvasive cortical assessment and neuromodulation techniques for stroke rehabilitation; regaining motor control and function can be facilitated through the induction of plasticity.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - January 22, 2019 Category: Neurology Authors: Kathleen E. Mantell, Samuel T. Nemanich, Ellen Sutter, Bernadette T. Gillick, Alexander Opitz Source Type: research
A single session of bihemispheric transcranial direct current stimulation does not improve quadriceps muscle spasticity in people with chronic stroke
Cerebral lesions following stroke cause an interhemispheric competition in the brain where the excitability of the affected hemisphere decreases and that of the unaffected hemisphere increases. This leads to a reduction of inhibitory control of spinal networks by the corticospinal tract of the affected side which in turn lead to the phenomenon of spasticity [1]. It has been found that i) bihemispheric-transcranial direct current stimulation (bi-tDCS) may reduce the interhemispheric imbalance in chronic stroke people (CSP) [2], and ii) anodal-tDCS applied over the affected leg motor cortex can alter the excitability of some...
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - June 27, 2019 Category: Neurology Authors: Thomas Cattagni, Maxime Geiger, Anthony Supiot, Rapha ël Zory, Didier Pradon, Nicolas Roche Source Type: research
The differential roles of contralesional frontoparietal areas in cortical reorganization after stroke
Studies examining the contribution of contralesional brain regions to motor recovery after stroke have revealed conflicting results comprising both supporting and disturbing influences. Especially the relevance of contralesional brain regions beyond primary motor cortex (M1) has rarely been studied, particularly concerning the temporal dynamics post-stroke.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - January 31, 2020 Category: Neurology Authors: Caroline Tscherpel, Lukas Hensel, Katharina Lemberg, Mattias Vollmer, Lukas J. Volz, Gereon R. Fink, Christian Grefkes Source Type: research
Integrating tDCS into Routine Inpatient Rehabilitation Practice to Boost Post-stroke Recovery
Transcranial direct current stimulation (tDCS), a non-invasive brain modulation tool, has gained popularity due to the portability, ease-of-use, and low cost. A majority of stroke recovery studies using tDCS have been focused on the chronic stage of recovery, as this time frame is relatively easy to conduct clinical trials and measure efficacy. However, studies during the chronic stage likely miss a window of opportunity where dynamic brain plasticity is occurring, the acute and subacute stages after stroke.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - April 5, 2020 Category: Neurology Authors: Shreyansh Shah, Pratik Y. Chhatbar, Jody Feld, Wuwei Feng Source Type: research
Transcranial alternating current stimulation enhances speech comprehension in chronic post-stroke aphasia patients: A single-blind sham-controlled study
Aphasia is one of the most devastating complications following stroke [1]. Speech and language therapy (SLT) [2] is recommended for post-stroke aphasia (PSA), but the benefits remain limited. Several recent studies have examined the potential efficacy of combining SLT with various forms of non-invasive brain stimulation (NIBS), including transcranial magnetic stimulation (TMS) and transcranial direct current stimulation (tDCS). While tDCS is accepted by clinicians and patients due to low cost and documented safety, it has not proven effective for improving speech comprehension [3].
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - December 6, 2022 Category: Neurology Authors: Xiaohui Xie, Panpan Hu, Yanghua Tian, Kai Wang, Tongjian Bai Source Type: research
Left or right ear? A neuroimaging study using combined taVNS/fMRI to understand the interaction between ear stimulation target and lesion location in chronic stroke
Implanted vagus nerve stimulation (VNS) and transcutaneous auricular VNS (taVNS) have been primarily administered clinically to the unilateral-left vagus nerve. This left-only convention has proved clinically beneficial in brain disorders. However, in stroke survivors, the presence of a lesion in the brain may complicate VNS-mediated signaling, and it is important to understand the laterality effects of VNS in stroke survivors to optimize the intervention.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - July 27, 2023 Category: Neurology Authors: Xiaolong Peng, Brenna Baker-Vogel, Mutaz Sarhan, Edward B. Short, Wenzhen Zhu, Hesheng Liu, Steven Kautz, Bashar W. Badran Source Type: research
Customization of transcranial Direct Current Stimulation for susceptible populations including at the extremes of age, obesity, and stroke
Transcranial direct current stimulation (tDCS) is a neuromodulatory technique that delivers low-intensity currents facilitating or inhibiting spontaneous neuronal activity. Such noninvasive electrotherapies have a number of advantages that have been exploited in clinical practice; in particular, tDCS dose is easily customized by varying electrode number, position, size, shape, and current. Recent developments in computational models have further customized dose to individual subjects and cases. Finite Element Method models developed from high-resolution MRI scans are among the tools available today. Designing and interpret...
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - March 1, 2014 Category: Neurology Authors: Dennis Truong, Preet Minhas, Albert Mokrejs, Marom Bikson Tags: Abstracts Presented at NYC Neuromodulation 2013 Source Type: research
Talking and tDCS Treatment for Stroke Survivors with Aphasia
This pilot study involves the use of transcranial direct current stimulation (tDCS), in conjunction with speech-language therapy for aphasia. In recent years, researchers have investigated the use of noninvasive brain stimulation techniques such as TMS (transcranial magnetic stimulation) and tDCS for the modulation of brain activity to improve function post stroke. In contrast to TMS, administering speech-language therapy at the same time is feasible with tDCS since the environment is quiet. Although several studies include behavioral therapy, the specifics regarding the speech-language treatment have not been described, a...
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - March 1, 2014 Category: Neurology Authors: Elizabeth Galletta, Amy Vogel, Steven Baumann Tags: Abstracts Presented at NYC Neuromodulation 2013 Source Type: research
Speech-language neurorehabilitation: Preliminary results of tDCS and robotic arm training in single left ischemic stroke.
We report a preliminary trans-disciplinary study investigating changes in measures of speech/language processing subsequent to anodal or sham tDCS preceding robotic arm treatment.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - March 1, 2014 Category: Neurology Authors: Carolyn Falconer, Adam Buchwald, Dylan Edwards Tags: Abstracts Presented at NYC Neuromodulation 2013 Source Type: research
Ipsilateral corticomotor neurophysiology in children with perinatal stroke
Perinatal stroke (PS) causes most hemiparetic cerebral palsy. Persistence of ipsilateral corticomotor connections from unlesioned hemisphere to aff5cted hand are common and associated with worse function. Ipsilateral cortical neurophysiology is poorly understood and a therapeutic target. We hypothesized that ipsilateral motor cortex demonstrates the same neurophysiological properties as normal contralateral systems.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - March 1, 2014 Category: Neurology Authors: O. Damji, A. Kirton Tags: Abstracts Presented at NYC Neuromodulation 2013 Source Type: research
Broca's Area Damage is Necessary but not Sufficient to Induce After-effects of cathodal tDCS on the Unaffected Hemisphere in Post-stroke Aphasia
The inter-individual variability of behavioral effects after tDCS applied to the unaffected right hemisphere in stroke may be related to factors such as the lesion location.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - June 13, 2014 Category: Neurology Authors: C. Rosso, V. Perlbarg, R. Valabregue, C. Arbizu, S. Ferrieux, B. Alshawan, P. Vargas, A. Leger, C. Zavanone, J.C. Corvol, S. Meunier, S. Lehéricy, Y. Samson Source Type: research
Retrospective Safety and Efficacy of the DeepTMS in a variety of pathologies including refractory Major Depression, Bipolar Depression, Parkinsońs Disease, negative symptoms of Schizophrenia and Stroke in a clinical setting; an update on the post-Marketing experience in Chile
Repetitive transcranial magnetic stimulation (rTMS) has been proposed as add-on for the treatment of various pathologies, including refractory Major Depression (MD), Bipolar Depression (BD), Parkinsońs Disease (PD), negative symptoms of Schizophrenia (NS) and Stroke (ST). However, the effectiveness of the conventional rTMS in clinical settings is currently being debated. The novel Deep TMS H-coils can effectively stimulate deeper and larger brain regions than conventional rTMS coils, including the complete thickness of motor and prefrontal cortices, suggesting greater potential clinical efficacy.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - September 1, 2014 Category: Neurology Authors: Jimmy Stehberg, Francisco Torres, Esteban Villalón, Raúl Riquelme Tags: Poster Source Type: research
Effects of epidural cortical stimulation on motor recovery after a primary motor cortex ischemic stroke: preliminary results in a non-human primate model
Nearly 15 million people suffer from stroke every year worldwide. Spontaneous recovery is usually considered to be limited to 6 months. Rehabilitative therapies performed during the first weeks can enhance recovery; however 1/3 of the patients are left with some chronic deficit for which current rehabilitative treatments are limited. Cortical stimulation techniques have been proposed to enhance motor rehabilitation with promising results, but until now these techniques were only considered for research.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - January 29, 2015 Category: Neurology Authors: A. Balossier, C. Orset, O. Etard, C. Gakuba, E. Emery, D. Vivien Source Type: research
