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Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation
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Total 298 results found since Jan 2013.
Different Modulation Mechanisms on Functional Motor Network between High and Low Frequency rTMS in Stroke Patients with Motor Dysfunction
Objective: To investigate the differences of the therapeutic effects and influence on motor functional network between high and low frequency repetitive transcranial magnetic stimulation (rTMS) in stroke patients by using the resting state functional magnetic resonance imaging (rs-fMRI).
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - January 22, 2019 Category: Neurology Authors: Q. Mu, Z. Guo, C. Yang Source Type: research
Understanding and modulating walking recovery post stroke
Gait speed is an important determinant of walking recovery, and descending corticomotor control is a significant contributor to gait recovery poststroke. Several studies have shown that the presence or absence of a transcranial magnetic stimulation (TMS) –induced motor evoked potential (MEP) is related to upper limb functional recovery in acute and chronic stroke. However, conflicting information regarding MEP responses and walking outcomes exist. In this symposium, I will review studies that have examined the contribution of the ipsilesional and contralesional hemisphere to walking recovery.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - January 22, 2019 Category: Neurology Authors: S. Madhavan Source Type: research
Intermittent theta burst stimulation plus external counterpulsation for upper limb motor recovery after ischemic stroke
Background and Purpose: Upper limb dysfunction is common after ischemic stroke. The single application of intermittent theta burst stimulation (iTBS) or external counterpulsation (ECP) has been proved effectively to enhance the cortical motor excitability in previous researches. However, it still needs to verify the augment effect and its duration when these two treatments are applied orderly. We hypothesized that there was a synergistic effect of ECP followed by iTBS to upper limb function through the improvement in both the cerebral perfusion and neuron excitability.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - January 22, 2019 Category: Neurology Authors: W. He, T. Leung, H. Leung, L. Wong Source Type: research
Abstract #130: EEG Beta-band Coherence for Prognosis of Motor Recovery in Stroke Patients with tDCS-BCI Intervention
Introduction: Substantial evidence in the literature suggests how the transcranial Direct Current Stimulation (tDCS) can be used as a tool to modulate the motor activity and its applications in neurorehabilitation research. However, it is little explored whether the tDCS can be used in conjunction with Brain-Computer Interface (BCI) therapy for prognosticating the motor recovery in chronic stroke population.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - January 22, 2019 Category: Neurology Authors: Vikram Shenoy Handiru, Cuntai Guan, Kai Keng Ang, Effie Chew Source Type: research
Abstract #112: Recruitment Challenges in Infant Stroke and Non-Invasive Brain Stimulation Research: Demographics and Factors
Introduction: Recruitment, enrollment, and retention (RER) of participants is a crucial determinant of successful research. Unique challenges exist with RER of pediatric participants due to public perceptions regarding the safety of non-invasive brain stimulation (NIBS), and consent involving family agreement and participation. Pediatric NIBS research historically struggles with low enrollment, resulting in issues of heterogeneity, validity, and generalizability. Our lab is currently engaged in RER methods for a NIBS study investigating cortical excitability, corticospinal tract organization, and motor function of infants ...
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - January 22, 2019 Category: Neurology Authors: Jesse L. Kowalski, Samuel T. Nemanich, Raghavendra Rao, MIchael Georgieff, Jeremiah Menk, Kyle Rudser, Bernadette Gillick Source Type: research
Abstract #71: Effects of Repetitive Transcranial magnetic Stimulation on Cognition and Neuroplasticity in Subacute Stroke Patients
Introduction: The purpose of this study is to determine the cognitive improvement and neurophysiological effects of repetitive transcranial magnetic stimulation (rTMS) over the left dorsolateral prefrontal cortex(L-DLPFC) in subacute stroke patients.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - January 22, 2019 Category: Neurology Authors: Yeong Wook Kim Source Type: research
Proceedings #57: Recruitment Challenges in Infant Stroke and Non-Invasive Brain Stimulation Research: Demographics and Factors
Background: Recruitment, enrollment, and retention (RER) of participants is a crucial determinant of successful research. Unique challenges exist with RER of pediatric participants due to public perceptions regarding the safety of NIBS, and consent involving family agreement and participation. Pediatric non-invasive brain stimulation (NIBS) research historically struggles with low participant recruitment.[1] Sufficient participant enrollment in pediatric NIBS studies is vital to addressing issues of heterogeneity, validity, and generalizability.[2] Our lab is currently engaged in RER methods for a NIBS study investigating ...
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - June 22, 2019 Category: Neurology Authors: Jesse L. Kowalski, Samuel T. Nemanich, Raghavendra Rao, Michael Georgieff, Elizabeth Zorn, Jeremiah Menk, Kyle Rudser, Bernadette T. Gillick Source Type: research
Transcranial Direct Current Stimulation ASsociated With Physical-therapy In Acute Stroke Patients - the tDCS ASAP - a Randomized, Triple Blind, Sham-controlled Study
Transcranial Direct Current Stimulation has been increasing in popularity in the last few years. Despite vast amounts of articles on the use of tDCS on stroke patients, very little has been done during the acute phase.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - October 30, 2019 Category: Neurology Authors: Stephen Bornheim, Jean-Louis Croisier, Pierre Maquet, Jean-Fran çois Kaux Source Type: research
Effects of high-frequency repetitive transcranial magnetic stimulation over the contralesional motor cortex on motor recovery in severe hemiplegic stroke: a randomized clinical trial
The contralesional hemisphere compensation may play a critical role in the recovery of stroke when there is extensive damage to one hemisphere. There is little research on the treatment of hemiplegia by high-frequency repetitive transcranial magnetic stimulation (rTMS) delivered to the contralesional cortex.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - April 1, 2020 Category: Neurology Authors: Qi Wang, Dai Zhang, Ying-Yu Zhao, Hong Hai, Yue-Wen Ma Source Type: research
Phase-dependent transcranial magnetic stimulation of the lesioned hemisphere is accurate after stroke
Transcranial magnetic stimulation (TMS) can produce plastic changes within descending motor pathways and distributed brain networks [1-2]. It has been proposed that TMS could enhance post-stroke motor recovery by normalizing imbalanced sensorimotor network function and/or upregulating corticospinal output [3-4] but studies using TMS to boost motor recovery have shown heterogeneous results [5]. However, TMS has traditionally been delivered uncoupled from endogenous brain oscillatory activity, leading to indiscriminate application of individual TMS pulses across different, physiologically distinct brain states.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - July 16, 2020 Category: Neurology Authors: Sara J. Hussain, William Hayward, Farah Fourcand, Christoph Zrenner, Ulf Ziemann, Ethan R. Buch, Margaret K. Hayward, Leonardo G. Cohen Source Type: research
Predictive models for response to non-invasive brain stimulation in stroke: A critical review of opportunities and pitfalls
Noninvasive brain stimulation has been successfully applied to improve stroke-related impairments in different behavioral domains. Yet, clinical translation is limited by heterogenous outcomes within and across studies. It has been proposed to develop and apply noninvasive brain stimulation in a patient-tailored, precision medicine-guided fashion to maximize response rates and effect magnitude. An important prerequisite for this task is the ability to accurately predict the expected response of the individual patient.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - September 21, 2021 Category: Neurology Authors: Maximilian J. Wessel, Philip Egger, Friedhelm C. Hummel Source Type: research
Differential effects of anodal and dual tDCS on sensorimotor functions in chronic hemiparetic stroke patients
Previous tDCS studies in chronic stroke patients reported highly inconsistent effects on sensorimotor functions. Underlying reasons could be the selection of different kinematic parameters across studies and for different tDCS setups. We reasoned that tDCS may not simply induce global changes in a beneficial-adverse dichotomy, but rather that different sensorimotor kinematics are differentially affected. Furthermore, the often-postulated higher efficacy of bilateral-dual (bi-tDCS) over unilateral-anodal (ua-tDCS) could not yet be demonstrated consistently either.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - March 3, 2022 Category: Neurology Authors: Toni Muffel, Pei-Cheng Shih, Benjamin Kalloch, Vadim Nikulin, Arno Villringer, Bernhard Sehm Source Type: research
Assessment of safety and feasibility of non-invasive vagus nerve stimulation for treatment of acute stroke
Non-invasive vagus nerve stimulation (nVNS) using a hand-held stimulator placed on the neck is an FDA-approved treatment for primary headache disorders. The safety of nVNS is unknown in stroke patients.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - November 7, 2022 Category: Neurology Authors: Ethem Murat Arsava, Mehmet Akif Topcuoglu, Ilknur Ay, Atilla Ozcan Ozdemir, Ibrahim Levent Gungor, Canan Togay Isikay, Bijen Nazliel, Hasan Huseyin Kozak, Serefnur Ozturk, İbrahim Arda Yilmaz, Babur Dora, Hakan Ay, the TR-VENUS investigators Source Type: research
Early transcranial direct current stimulation with modified constraint-induced movement therapy for motor and functional upper limb recovery in hospitalized patients with stroke: A randomized, multicentre, double-blind, clinical trial
Constraint-induced movement therapy (CIMT) and transcranial direct current stimulation (tDCS) are used to reduce interhemispheric imbalance after stroke, which is why the combination of these therapies has been used for neurological recovery, but not in the acute phase.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - December 27, 2022 Category: Neurology Authors: Maricel Garrido M, Evelyn Alvarez E, Fabrizio Acevedo P, Álvaro Moyano V, Natalia Castillo N, Gabriel Cavada Ch Source Type: research
Sphenopalatine ganglion stimulation to treat acute ischemic stroke
Symposium title: Neuromodulation for acute stroke treatment, prevention and recovery
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - January 1, 2023 Category: Neurology Authors: Natan Borstein Source Type: research
