Phase-dependent transcranial magnetic stimulation of the lesioned hemisphere is accurate after stroke

Transcranial magnetic stimulation (TMS) can produce plastic changes within descending motor pathways and distributed brain networks [1-2]. It has been proposed that TMS could enhance post-stroke motor recovery by normalizing imbalanced sensorimotor network function and/or upregulating corticospinal output [3-4] but studies using TMS to boost motor recovery have shown heterogeneous results [5]. However, TMS has traditionally been delivered uncoupled from endogenous brain oscillatory activity, leading to indiscriminate application of individual TMS pulses across different, physiologically distinct brain states.

Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - July 16, 2020 Category: Neurology Authors: Sara J. Hussain, William Hayward, Farah Fourcand, Christoph Zrenner, Ulf Ziemann, Ethan R. Buch, Margaret K. Hayward, Leonardo G. Cohen Source Type: research