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Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation

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Total 298 results found since Jan 2013.

The effects of aerobic exercise on motor cortex plasticity in chronic stroke survivors with and without post-stroke depression: a preliminary report
Abstract
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - November 1, 2021 Category: Neurology Authors: Ryan Ross, Catherine VanDerwerker, Ewan Williams, Mark George, Steven Kautz, Chris Gregory Source Type: research

Ipsilateral corticospinal maps correspond to severe poststroke motor impairment
Motor recovery in the chronic stage, i.e., more than 6 months after stroke is often limited. While there is increasing interest in the development of novel therapies for this patient cohort [1], only very few trials focus on severely impaired chronic stroke patients [2]. Refined therapies are therefore required for this patient population. Furthermore, reliable measures for studying the underlying physiological mechanisms and effectiveness of interventions are crucial. In this context, cortical motor maps appear to be promising, i.e., by assessing the cortical representation of the affected muscles as measured by motor evo...
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - May 10, 2022 Category: Neurology Authors: Bettina Hanna Trunk, Lukas Ziegler, Alireza Gharabaghi Source Type: research

Personalized electric field modeling for transcranial electrical stimulation on stroke patients: a comparison of open-source pipelines, with versus without manual stroke delineation
Abstract
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - January 1, 2023 Category: Neurology Authors: Ziping Huang, Riki Shimizu, Jody Feld, Estate Sokhadze, Pratik Chhatbar, Wuwei Feng Source Type: research

Corticospinal excitability in patients with anoxic, traumatic, and non-traumatic diffuse brain injury
Conclusions: The present study demonstrated the impairment of the cortical inhibitory circuits in patients with brain injury of traumatic and non-traumatic aetiology. Moreover, the significant correlation was found between the amount of SICI and the severity of brain injury.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - April 19, 2012 Category: Neurology Authors: Natallia Lapitskaya, Sofie Kirial Moerk, Olivia Gosseries, Joergen Feldbaek Nielsen, Alain Maertens de Noordhout Tags: Original Articles Source Type: research

Eyelid Myokymia in an Older Subject After Repetitive Sessions of Anodal Transcranial Direct Current Stimulation
Non-invasive brain stimulation techniques have developed into useful tools to study brain functions, like motor learning , physiological changes of the brain like during healthy aging or pathological conditions (e.g., stroke, parkinson, tinnitus, among others) . Furthermore they are more and more applied and evaluated as therapeutic tools to treat neuropsychiatric diseases . The evolution of these techniques emphasizes the importance to report possible adverse effects. Here, we present a case with occurrence of monocular eyelid myokymia after repetitive application of anodal transcranial direct current stimulation (tDCS) to the motor cortex.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - November 5, 2012 Category: Neurology Authors: M. Wessel, M. Zimerman, J.E. Timmermann, F.C. Hummel Tags: Letters to the Editor Source Type: research

A Non-Epileptiform Event in the Course of rTMS: A Case for Close Physician Monitoring
We present the following case to demonstrate the importance of having physician supervision of patients undergoing repetitive transcranial magnetic stimulation (rTMS) treatments. The patient was a married 60-year-old male with a diagnosis of Major Depressive Disorder and Generalized Anxiety Disorder who had continuous symptoms of depression since the early 1980s despite receiving at least 7 adequate antidepressant treatments. The patient had several comorbid medical conditions. The patient did not have any previous history of seizure, stroke, an abnormal EEG, head injury, neurosurgical procedure, implanted devices, frequen...
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - April 29, 2013 Category: Neurology Authors: F. Andrew Kozel, Paul E. Croarkin, Kimberly S. Mapes Tags: Letters to the Editor Source Type: research

Connectivity between Right Inferior Frontal Gyrus and Supplementary Motor Area Predicts After-Effects of Right Frontal Cathodal tDCS on Picture Naming Speed
Conclusions: The results support the notion that the after-effects of tDCS on brain function are at least in part determined by the anatomical and functional connectivity of the targeted region.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - September 27, 2013 Category: Neurology Authors: Charlotte Rosso, R. Valabregue, C. Arbizu, S. Ferrieux, P. Vargas, F. Humbert, Y. Attal, A. Messé, C. Zavanone, S. Meunier, L. Cohen, C. Delmaire, A. Thielscher, D.M. Herz, H.R. Siebner, Y. Samson, S. Lehéricy Tags: Original Research Source Type: research

HD-tDCS to enhance behavioral treatment for aphasia: A feasibility study
Transcranial direct current stimulation (tDCS) enhances treatment outcomes post-stroke. Effects depend largely on which cortical areas are targeted. Feasibility and tolerability of high-definition (HD) tDCS, a technique that is thought to increase current focality and intensity, for consecutive weekdays as an adjunct to behavioral treatment in a clinical population has not been demonstrated.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - March 1, 2014 Category: Neurology Authors: Jessica D. Richardson, Abhishek Datta, Jacek Dmochowski, Lucas Parra, Julius Fridriksson Tags: Abstracts Presented at NYC Neuromodulation 2013 Source Type: research

BDNF Polymorphism and Differential rTMS Effects on Motor Recovery of Stroke Patients
The brain-derived neurotrophic factor (BDNF) gene often shows a single nucleotide polymorphism that is thought to influence synaptic plasticity. It also affects the modulatory effects of repetitive transcranial magnetic stimulation (rTMS) on motor cortex excitability.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - March 28, 2014 Category: Neurology Authors: Won Hyuk Chang, Oh Young Bang, Yong-Il Shin, Ahee Lee, Alvaro Pascual-Leone, Yun-Hee Kim Tags: Original Articles Source Type: research

Val66Met BDNF Gene Polymorphism Influences Human Motor Cortex Plasticity in Acute Stroke
BDNF gene polymorphism impacts human motor cortex function and plasticity.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - August 22, 2014 Category: Neurology Authors: Vincenzo Di Lazzaro, Giovanni Pellegrino, Giovanni Di Pino, Marzia Corbetto, Federico Ranieri, Nicoletta Brunelli, Matteo Paolucci, Serena Bucossi, Maria C. Ventriglia, Peter Brown, Fioravante Capone Tags: Original Research Source Type: research

The outlook for non-invasive electrical brain stimulation
Over a decade since the initial establishment of modern transcranial direct current stimulation (tDCS), the field of transcranial electrical stimulation (tES) has blossomed to include a range of techniques (e.g., alternating current (tACS), random noise (tRNS), and pulsed current stimulation), and a diverse array of applications (e.g., depression, pain, tinnitus, stroke, and schizophrenia). At the cusp of even broader dissemination of tES as a tool for the treatment and rehabilitation of brain disorders, the study of brain function, and brain enhancement, it is incumbent to consolidate what have we learned and what remains to be addressed.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - October 23, 2014 Category: Neurology Authors: Marom Bikson, Dylan Edwards, Emily Kappenman Source Type: research

Electrical Stimulation of the Vagus Nerve Dermatome in the External Ear is Protective in Rat Cerebral Ischemia
Although cervical vagus nerve stimulation is effective for reducing infarct volume in rats, it is not feasible for acute human stroke as it requires surgical incision of the neck. We hypothesized that stimulation of the dermatome in the external ear innervated by the vagus nerve (auricular vagus nerve stimulation; aVNS) reduces infarct volume after transient focal ischemia in rats.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - September 25, 2014 Category: Neurology Authors: Ilknur Ay, Vitaly Napadow, Hakan Ay Tags: Original Research Source Type: research

Safety of Noninvasive Brain Stimulation in Children and Adolescents
Noninvasive brain stimulation (NIBS) techniques such as transcranial magnetic stimulation (TMS) and transcranial current stimulation (tCS) have the potential to mitigate a variety of symptoms associated with neurological and psychiatric conditions, including stroke, cerebral palsy, autism, depression, and Tourette syndrome. While the safety of these modalities has been established in adults, there is a paucity of research assessing the safety of NIBS among children.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - October 27, 2014 Category: Neurology Authors: Chandramouli Krishnan, Luciana Santos, Mark D. Peterson, Margaret Ehinger Source Type: research

Treatment of Post-stroke Motor Dsyfunction by Interleaved Trancranial Magnetic Stimulation Combined with Functional MRI (TMS-fMRI)
Transcranial magnetic stimulation (TMS) was first used by Anthony Baker and his co-investigators in 1985. They used TMS to induce weak electric currents of 1.0 Hz or less to stimulate and promote a neural metabolic response within the cerebral nervous system. This resulted not only in a physical response but a functional response as well. Further investigations and experimentation though the manipulation of repetitive TMS pulses has shown either increases or decreases in the promotion of neural transmissions depending upon the coil orientation of the TMS device, intensity of the magnetic pulse as well as its frequency.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - January 29, 2015 Category: Neurology Authors: Qiwen Mu, Huaping Chen, Bin He, Zhiwei Guo, Jun Ou, Morgan A. McClure Source Type: research