Ipsilateral corticospinal maps correspond to severe poststroke motor impairment

Motor recovery in the chronic stage, i.e., more than 6 months after stroke is often limited. While there is increasing interest in the development of novel therapies for this patient cohort [1], only very few trials focus on severely impaired chronic stroke patients [2]. Refined therapies are therefore required for this patient population. Furthermore, reliable measures for studying the underlying physiological mechanisms and effectiveness of interventions are crucial. In this context, cortical motor maps appear to be promising, i.e., by assessing the cortical representation of the affected muscles as measured by motor evoked potentials (MEP) following transcranial magnetic stimulation (TMS) [3].

Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - May 10, 2022 Category: Neurology Authors: Bettina Hanna Trunk, Lukas Ziegler, Alireza Gharabaghi Source Type: research