The role of inhibition in motor performance and learning

Introduction: Understanding the neurophysiological underpinnings of motor plasticity is of prime importance, not least for developing novel therapeutic approaches after a stroke. There is substantial evidence from animal models to support the hypothesis that modulation of GABA, the major inhibitory neurotransmitter, is a necessary step in motor learning. However, until recently it has been difficult to assess whether GABA is necessary for plasticity in vivo in humans.

Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - February 15, 2017 Category: Neurology Authors: J. Kolasinski, A. Johnstone, V. Bachtiar, C.J. Stagg Source Type: research