Intervention induced intra-cortical plasticity in hemiparetic children with perinatal stroke

Introduction: Clinical trials are demonstrating efficacy of intensive hand training and/or brain stimulation therapies in improving hand function in hemiparetic children with perinatal stroke. However, high variability in individual responsiveness exists and the underlying neuroplasticity mechanisms responsible are virtually unknown. The neurophysiology of motor cortex (M1) and how it changes with therapeutic neuromodulation may provide valuable biomarkers for advancing treatments, patient selection, and personalized medicine.

Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - February 15, 2017 Category: Neurology Authors: H.C. Kuo, E. Zewdie, P. Ciechanski, A. Kirton Source Type: research