Targeting interhemispheric inhibition with neuromodulation to enhance stroke rehabilitation

Interhemispheric inhibition in the brain plays a dynamic role in the production of voluntary unimanual actions. In stroke, the interhemispheric imbalance model predicts the presence of asymmetry in interhemispheric inhibition, with excessive inhibition from the contralesional hemisphere limiting maximal recovery. Stimulation methods to reduce this asymmetry in the brain may be promising as a stroke therapy, however determining how to best measure and modulate interhemispheric inhibition and who is likely to benefit, remain important questions.

Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - January 12, 2017 Category: Neurology Authors: L.J. Boddington, J.N.J. Reynolds Source Type: research