Imaging brain plasticity in stroke patients with simultaneous paired associative stimulation PAS /fMRI

Introduction: Paired associative stimulation (PAS) is a non-invasive brain stimulation technique where two neural substrates are employed in a temporally coordinated manner in order to modulate cortico-motor excitability, typically within the motor cortex (M1). PAS effects are easiest to study in the motor system, although others have examined PAS with EEG and other techniques in non-motor areas. Here, we aimed to investigate brain connectivity changes during PAS treatment using interleaved PAS/functional magnetic resonance imaging (fMRI) in stroke patients compared to healthy controls.

Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - January 22, 2019 Category: Neurology Authors: X. Li, M. George, W. Feng, T. Brown, M. Woodbury, S. Kautz Source Type: research