Stability of the Cardiovascular Response during Single-pulse TMS in Perinatal Stroke

Serious adverse events of syncope have been reported with single pulse transcranial magnetic stimulation (sp-TMS) in both healthy adults and adolescents post stroke [3, 5, 7-9]. Despite these reports, the physiological mechanisms leading to syncope during sp-TMS administration are not clearly understood. A syncopal event is classically identified by a sudden, large reduction in blood supply to neural tissue “cerebral hypoperfusion” to ultimately cause a loss of consciousness [2]. Common symptoms preceding syncope include lightheadedness, nausea, diaphoresis, and/or visual changes.

Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - November 20, 2018 Category: Neurology Authors: Manda L. Keller-Ross, Daniel P. Chantigian, Mo Chen, Tonya L. Rich, Chao-Ying Chen, Bernadette T. Gillick Source Type: research