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Specialty: Neurology
Condition: Multiple Sclerosis
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Total 440 results found since Jan 2013.
Clinical diagnostic utility of transcranial magnetic stimulation in neurological disorders. Updated report of an IFCN committee
Clin Neurophysiol. 2023 Mar 29;150:131-175. doi: 10.1016/j.clinph.2023.03.010. Online ahead of print.ABSTRACTThe review provides a comprehensive update (previous report: Chen R, Cros D, Curra A, Di Lazzaro V, Lefaucheur JP, Magistris MR, et al. The clinical diagnostic utility of transcranial magnetic stimulation: report of an IFCN committee. Clin Neurophysiol 2008;119(3):504-32) on clinical diagnostic utility of transcranial magnetic stimulation (TMS) in neurological diseases. Most TMS measures rely on stimulation of motor cortex and recording of motor evoked potentials. Paired-pulse TMS techniques, incorporating conventio...
Source: Clinical Neurophysiology - April 17, 2023 Category: Neurology Authors: Steve Vucic Kai-Hsiang Stanley Chen Matthew C Kiernan Mark Hallett David H Benninger Vincenzo Di Lazzaro Paolo M Rossini Alberto Benussi Alfredo Berardelli Antonio Curr à Sandro M Krieg Jean-Pascal Lefaucheur Yew Long Lo Richard A Macdonell Marcello Mass Source Type: research
Clinical efficacy of botulinum toxin type A in patients with traumatic brain injury, spinal cord injury, or multiple sclerosis: An observational longitudinal study
This study aims to clarify the role of BoNT-A in the context of non-stroke spasticity (NSS). We enrolled 86 patients affected by multiple sclerosis, spinal cord injury, and traumatic brain injury with clinical indication to perform BoNT-A treatment. Subjects were evaluated before injection and after 1, 3, and 6 months. At every visit, spasticity severity using the modified Ashworth scale, pain using the numeric rating scale, QoL using the Euro Qol Group EQ-5D-5L, and the perceived treatment effect using the Global Assessment of Efficacy scale were recorded. In our population BoNT-A demonstrated to have a significant effect...
Source: Frontiers in Neurology - April 6, 2023 Category: Neurology Source Type: research
Good multiple sclerosis (MS) care and how to get there in Canada: Perspectives of Canadian healthcare providers working with persons with MS
ConclusionTo meet the care needs of Canadians with MS, the healthcare system must consider standardizing and funding multidisciplinary team-based MS clinics, comparable to Stroke units, which continue to show favorable health outcomes after years of implementation.
Source: Frontiers in Neurology - March 2, 2023 Category: Neurology Source Type: research
Sphingosine-1-phosphate Signalling in Aneurysmal Subarachnoid Haemorrhage: Basic Science to Clinical Translation
AbstractSphingosine-1-phosphate (S1P) is generated intracellularly and, when transported to the extracellular compartment, predominantly signals through S1P receptors. The S1P signalling pathway has been implicated in the pathophysiology of neurological injury following aneurysmal subarachnoid haemorrhage (aSAH). In this review, we bring together all the available data regarding the role of S1P in neurological injury following aSAH. There is agreement in the literature that S1P increases in the cerebrospinal fluid following aSAH and leads to cerebral artery vasospasm. On the other hand, the role of S1P in the parenchyma is...
Source: Translational Stroke Research - February 7, 2023 Category: Neurology Source Type: research
The importance of neuromuscular rate of force development for physical function in aging and common neurodegenerative disorders - a systematic review
J Musculoskelet Neuronal Interact. 2022 Dec 1;22(4):562-586.ABSTRACTWe systematically reviewed existing literature regarding lower extremity neuromuscular rate of force development (RFD), maximal muscle strength (Fmax), and physical function in neurodegenerative populations, and to what extent these outcomes are affected and/or associated. Following PRISMA guidelines, 4 databases (Pubmed, Embase, SPORTDiscus, Web of Science) were searched. Across aging, Parkinson Disease (PD), Alzheimer's Disease (AD), Multiple Sclerosis (MS), or Stroke, included studies should report (Part 1) deficits in lower extremity RFD, Fmax, and phy...
Source: Journal of Musculoskeletal Neuronal Interactions - December 2, 2022 Category: Neurology Authors: Sidsel D Lomborg Ulrik Dalgas Lars G Hvid Source Type: research
