EEG findings in COVID-19 related encephalopathy.
cci R PMID: 32736327 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - July 18, 2020 Category: Neurology Authors: Pasini E, Bisulli F, Volpi L, Minardi I, Tappatà M, Muccioli L, Pensato U, Riguzzi P, Tinuper P, Michelucci R Tags: Clin Neurophysiol Source Type: research

Optimized set of criteria for defining interictal epileptiform EEG discharges.
CONCLUSIONS: The optimized set of criteria for defining IEDs has high accuracy and IRA. SIGNIFICANCE: Using these criteria will contribute to decreasing over-reading of EEG and avoid misdiagnosis of epilepsy. PMID: 32731161 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - July 17, 2020 Category: Neurology Authors: Kural MA, Tankisi H, Duez L, Sejer Hansen V, Udupi A, Wennberg R, Rampp S, Larsson PG, Schulz R, Beniczky S Tags: Clin Neurophysiol Source Type: research

Error and post-error processing in children with attention-deficit/hyperactivity disorder: An electrical neuroimaging study.
CONCLUSIONS: Self-regulation deficits in ADHD are associated with later stages of error processing and subsequent implementation of cognitive control. SIGNIFICANCE: We contribute to the literature by further specifying error processing deficits in ADHD. PMID: 32721844 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - July 14, 2020 Category: Neurology Authors: Janssen TWP, van Atteveldt N, Oosterlaan J Tags: Clin Neurophysiol Source Type: research

Central sensitization of nociceptive pathways demonstrated by robot-controlled pinprick-evoked brain potentials.
CONCLUSIONS: This study shows increased PEPs after HFS when they are elicited by a robot-controlled mechanical pinprick stimulator and participants are engaged in a stimulus evaluation task during pinprick stimulation. SIGNIFICANCE: This is the first study that shows a significant increase of both PEP peaks, and therefore, it provides a preferred setup for assessing the function of mechanical nociceptive pathways in the context of central sensitization. PMID: 32709556 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - July 9, 2020 Category: Neurology Authors: van den Broeke EN, de Hemptinne P, Mercken M, Torta DM, Lambert J, Mouraux A Tags: Clin Neurophysiol Source Type: research

Reduced EEG montage has a high accuracy in the post cardiac arrest setting.
CONCLUSION: Reduced EEG had high performance for classifying important background and discharge patterns in this post cardiac arrest cohort. SIGNIFICANCE: Our results support the use of reduced EEG-montage for monitoring comatose cardiac arrest patients. PMID: 32711346 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - July 9, 2020 Category: Neurology Authors: Backman S, Cronberg T, Rosén I, Westhall E Tags: Clin Neurophysiol Source Type: research

Motor unit number index as an individual biomarker: Reference limits of intra-individual variability over time in healthy subjects.
CONCLUSIONS: The MUNIX technique must be performed by experienced operators on several muscles to reduce its variability and improve its reliability. SIGNIFICANCE: A variation of the MUNIX sum score ≥20% can be interpreted as a significant change of muscle innervation. PMID: 32707479 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - July 9, 2020 Category: Neurology Authors: Delmont E, Wang F, Lefaucheur JP, Puma A, Breniere C, Beaudonnet G, Cintas P, Collin R, Fortanier E, Grapperon AM, Jomir L, Kribich H, Kouton L, Kuntzer T, Lenglet T, Magot A, Nordine T, Ochsner F, Bolloy G, Pereon Y, Salort-Campana E, Tard C, Vicino A, V Tags: Clin Neurophysiol Source Type: research

Reproducibility and reaction time of swallowing as markers of dysphagia in parkinsonian syndromes.
CONCLUSIONS: Increased variability of oral swallowing automatisms and abnormal sensorimotor integration may be of relevance for the pathophysiology of dysphagia in parkinsonian syndromes. SIGNIFICANCE: The electrophysiological assessment represents a valuable tool to investigate swallowing alterations in parkinsonian syndromes. It may also provide useful insights into clinical severity and pathophysiology of dysphagia, giving clues for the choice of the best therapeutic approach. PMID: 32702534 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - July 9, 2020 Category: Neurology Authors: Cosentino G, Tassorelli C, Prunetti P, Todisco M, De Icco R, Avenali M, Minafra B, Zangaglia R, Valentino F, Pacchetti C, Bertino G, Mauramati S, Fresia M, Alfonsi E Tags: Clin Neurophysiol Source Type: research

Assessment of age-related differences in decomposition-based quantitative EMG in the intrinsic hand muscles: A multivariate approach.
CONCLUSIONS: With aging, there are decreases in motor unit number estimation and stability in the intrinsic hand muscles. Using a multivariate approach allows for age-related differences and the relationship between the variables to be further elucidated. SIGNIFICANCE: Multivariate analysis of DQEMG may be useful for identifying patterns of change in neuromuscular physiology with age-related changes to hand musculature. This may potentially lead to future prognostic biomarkers of age-related changes to hand muscles. PMID: 32693193 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - July 9, 2020 Category: Neurology Authors: Tsang P, MacDermid JC, Miller TA, Doherty TJ, Ross DC Tags: Clin Neurophysiol Source Type: research

Age-related decline of neuroplasticity to intermittent theta burst stimulation of the lateral prefrontal cortex and its relationship with late-life memory performance.
CONCLUSIONS: These findings suggest that neuroplasticity in the human lateral prefrontal cortex is reduced in older relative to young adults, and this may be an important factor in age-related memory decline. SIGNIFICANCE: This may have important implications for the early detection of cognitive decline and dementia. PMID: 32693192 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - July 3, 2020 Category: Neurology Authors: Goldsworthy MR, Rogasch NC, Ballinger S, Graetz L, Van Dam JM, Harris R, Yu S, Pitcher JB, Baune BT, Ridding MC Tags: Clin Neurophysiol Source Type: research

Deficits in monitoring self-produced speech in Parkinson's disease.
CONCLUSIONS: The finding indicates that auditory evoked activity is abnormally modulated during speech in Parkinson's patients who do not subjectively notice speech impairment. This mechanism could play a role in producing speech deficits in as the disease progresses. SIGNIFICANCE: Our study is the first to show abnormal early auditory electrophysiological correlates of monitoring speech in Parkinson's disease patients. PMID: 32682241 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - July 3, 2020 Category: Neurology Authors: Railo H, Nokelainen N, Savolainen S, Kaasinen V Tags: Clin Neurophysiol Source Type: research

Neurophysiology to guide acute stroke treatment.
PMID: 32674960 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - July 2, 2020 Category: Neurology Authors: Stinear CM, Barber PA Tags: Clin Neurophysiol Source Type: research

Corrigendum to "A controlled clinical crossover trial of exercise training to improve cognition and neural communication in pediatric brain tumor survivors" [Clin. Neurophysiol. 131 (2020) 1533-1547].
Corrigendum to "A controlled clinical crossover trial of exercise training to improve cognition and neural communication in pediatric brain tumor survivors" [Clin. Neurophysiol. 131 (2020) 1533-1547]. Clin Neurophysiol. 2020 Jul 01;: Authors: Cox E, Bells S, Timmons BW, Laughlin S, Bouffet E, de Medeiros C, Beera K, Harasym D, Mabbott DJ PMID: 32622585 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - July 1, 2020 Category: Neurology Authors: Cox E, Bells S, Timmons BW, Laughlin S, Bouffet E, de Medeiros C, Beera K, Harasym D, Mabbott DJ Tags: Clin Neurophysiol Source Type: research

COVID-19 associated encephalopathy: Is there a specific EEG pattern?
PMID: 32615526 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - June 24, 2020 Category: Neurology Authors: Vellieux G, Rouvel-Tallec A, Jaquet P, Grinea A, Sonneville R, d'Ortho MP Tags: Clin Neurophysiol Source Type: research

Central motor conduction time reveals upper motor neuron involvement masked by lower motor neuron impairment in a significant portion of patients with amyotrophic lateral sclerosis.
CONCLUSIONS: CMCT shows UMN dysfunction in ALS patients without clinical UMN impairment. SIGNIFICANCE: TMS still has diagnostic utility in a significant portion of ALS patients. PMID: 32593964 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - June 12, 2020 Category: Neurology Authors: Tokimura R, Murakami T, Ugawa Y Tags: Clin Neurophysiol Source Type: research

The effects of antiepileptic drugs on high-frequency oscillations in somatosensory evoked potentials.
CONCLUSION: Our results demonstrate that SEP-HFOs are sensitive to the action of AEDs on cortical excitability. This effect seems to affect mainly the cortical component of HFOs in the AH and it is related to the number of AEDs taken. SIGNIFICANCE: SEP-HFOs might be a viable tool to probe cortical excitability changes induced by AEDs. PMID: 32599275 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - June 12, 2020 Category: Neurology Authors: Lanzone J, Boscarino M, Ricci L, Insola A, Tombini M, Di Lazzaro V, Assenza G Tags: Clin Neurophysiol Source Type: research

EEG autoregressive modeling analysis: A diagnostic tool for patients with epilepsy without epileptiform discharges.
CONCLUSIONS: Our proposed method can help neurologists in the early diagnosis of epilepsy in patients without EDs and might help in differentiating between nonepileptic paroxysmal events and epilepsy. SIGNIFICANCE: EEG AR model prediction errors could be used as an alternative diagnostic marker of epilepsy. PMID: 32599273 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - June 8, 2020 Category: Neurology Authors: Ouyang CS, Yang RC, Chiang CT, Wu RC, Lin LC Tags: Clin Neurophysiol Source Type: research

Family nurture intervention alters relationships between preterm infant EEG delta brush characteristics and term age EEG power.
CONCLUSIONS: DBs are related to subsequent brain activity and FNI alters DB parameters. However, FNI's effects on electrocortical activity at term age are not dependent on its earlier effects on DBs. SIGNIFICANCE: While early DBs can have important effects on later brain activity in preterm infants, facilitating emotional connection with FNI may allow brain maturation to be less dependent on early bursts. PMID: 32599274 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - June 8, 2020 Category: Neurology Authors: Welch MG, Grieve PG, Barone JL, Ludwig RJ, Stark RI, Isler JR, Myers MM Tags: Clin Neurophysiol Source Type: research

Separating posterior-circulation stroke from vestibular neuritis with quantitative vestibular testing.
CONCLUSION: vHIT provided the best separation of VN from PCS. VOR-gain, refixation-saccade prevalence and amplitude were effective discriminators of VN from PCS. SIGNIFICANCE: vHIT and oVEMP could assist early identification of the aetiology of Acute Vestibular Syndrome in the Emergency Room. PMID: 32600960 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - June 8, 2020 Category: Neurology Authors: Calic Z, Nham B, Bradshaw AP, Young AS, Bhaskar S, D'Souza M, Anderson CS, Cappelen-Smith C, Cordato D, Welgampola MS Tags: Clin Neurophysiol Source Type: research

Temporal regularity of cerebral activity at rest correlates with slowness of reaction times in intellectual disability.
Abstract OBJECTIVE: Intellectual disability (ID) is described as a general slowness in behavior and an inadequacy in adaptive skills. The present study examines whether behavioral slowness in ID could originate from abnormal complexity in brain signals. METHODS: Participants (N = 29) performed a reaction times (RTs) task assessing their individual information processing speeds. Half of the participants had moderate intellectual disability (intelligence quotient (IQ) 
Source: Clinical Neurophysiology - June 8, 2020 Category: Neurology Authors: Palix J, Giuliani F, Sierro G, Brandner C, Favrod J Tags: Clin Neurophysiol Source Type: research

Quantitative EEG markers to prognosticate critically ill patients with COVID-19: A retrospective cohort study.
PMID: 32544837 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - June 6, 2020 Category: Neurology Authors: Pati S, Toth E, Chaitanya G Tags: Clin Neurophysiol Source Type: research

Identifying the epileptogenic zone by four non-invasive imaging techniques versus stereo-EEG in MRI-negative pre-surgery epilepsy patients.
CONCLUSIONS: The study highlights the accuracy of a combination of functional imaging techniques in the identification of EZ in MRI negative focal epilepsy. The best diagnostic yield was obtained if the combination of PET, MEG (or HR-EEG as alternative), EEG-fMRI were considered together. SIGNIFICANCE: The functional imaging techniques may improve the presurgical workup of MRI negative focal epilepsy, if epileptogenic zone involves more than one lobe. PMID: 32544836 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - June 3, 2020 Category: Neurology Authors: Rossi Sebastiano D, Tassi L, Duran D, Visani E, Gozzo F, Cardinale F, Nobili L, Del Sole A, Rubino A, Dotta S, Schiaffi E, Garbelli R, Franceschetti S, Spreafico R, Panzica F Tags: Clin Neurophysiol Source Type: research

Pathophysiology of rigidity in Parkinson's disease: Another step forward.
PMID: 32507558 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - May 29, 2020 Category: Neurology Authors: Bologna M, Paparella G Tags: Clin Neurophysiol Source Type: research

Seizure onset location shapes dynamics of initiation.
CONCLUSIONS: Our findings suggest that the onset region sculpts neurodynamics at seizure initiation and that unique features of the cytoarchitecture and/or connectivity of that region play a significant role in determining seizure mechanism. SIGNIFICANCE: To learn how seizures are initiated, researchers would do well to consider other aspects of their manifestation, in addition to their electrographic patterns. Examination of onset pattern in conjunction with the interactions between different oscillatory frequencies in the context of different brain regions might be more informative and lead to more reliable clinical...
Source: Clinical Neurophysiology - May 29, 2020 Category: Neurology Authors: Salami P, Peled N, Nadalin JK, Martinet LE, Kramer MA, Lee JW, Cash SS Tags: Clin Neurophysiol Source Type: research

Split-hand phenomenon in motor neuron diseases: Sonographic assesment of muscle thickness.
CONCLUSIONS: SHI determined by sonographic measurement of hand muscle thickness seems to be a promising tool for the diagnosis of ALS and may be added easily when performing neuromuscular ultrasound. SIGNIFICANCE: SHI determined by sonographic measurement of hand muscle thickness can differentiate between healthy subjects and patients with ALS and SMA. PMID: 32504931 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - May 22, 2020 Category: Neurology Authors: Abraham A, Fainmesser Y, Drory VE, Bril V Tags: Clin Neurophysiol Source Type: research

Thalamic and cortical hyperexcitability in juvenile myoclonic epilepsy.
Abstract OBJECTIVES: Juvenile myoclonic epilepsy (JME) is a genetic generalized epilepsy marked by cortical hyperexcitability. Recent neuroimaging data suggested also a thalamic role in sustaining epileptic propensity in JME. However, thalamic hyperexcitability was not demonstrated so far. Low-frequency (LF-SEPs) and high-frequency somatosensory evoked potentials (HF-SEPs) are very sensitive to thalamic (early HF-SEPs burst, eHFO) and cortical (late HF-SEPs burst, lHFO) excitability. The aim of our experiment was to explore and discern the role of thalamic and cortical excitability in epileptic susceptibility of J...
Source: Clinical Neurophysiology - May 22, 2020 Category: Neurology Authors: Assenza G, Lanzone J, Dubbioso R, Coppola A, Boscarino M, Ricci L, Insola A, Bilo L, Tombini M, Di Lazzaro V Tags: Clin Neurophysiol Source Type: research

Pay more attention to EEG in COVID-19 pandemic.
PMID: 32482439 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - May 22, 2020 Category: Neurology Authors: Flamand M, Perron A, Buron Y, Szurhaj W Tags: Clin Neurophysiol Source Type: research

Erratum to "Smaller increase in delta post-ictal suppression in magnetic seizure therapy than electroconvulsive therapy in geriatric patients with severe depression: A multi-case study" [Clin. Neurophysiol. 131 (2020) 1219-1220].
Erratum to "Smaller increase in delta post-ictal suppression in magnetic seizure therapy than electroconvulsive therapy in geriatric patients with severe depression: A multi-case study" [Clin. Neurophysiol. 131 (2020) 1219-1220]. Clin Neurophysiol. 2020 May 16;: Authors: Rowny SB, Ly MT, Kluisza L, Casal-Roscum L, Prudic J, Chen CM PMID: 32430168 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - May 16, 2020 Category: Neurology Authors: Rowny SB, Ly MT, Kluisza L, Casal-Roscum L, Prudic J, Chen CM Tags: Clin Neurophysiol Source Type: research

Non-lesional status epilepticus in a patient with coronavirus disease 2019.
Magot A, Peyre A PMID: 32405258 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - May 13, 2020 Category: Neurology Authors: Balloy G, Mahé PJ, Leclair-Visonneau L, Péréon Y, Derkinderen P, Magot A, Peyre A Tags: Clin Neurophysiol Source Type: research

How to carry out and interpret EEG recordings in COVID-19 patients in ICU?
Abstract There are questions and challenges regarding neurologic complications in COVID-19 patients. EEG is a safe and efficient tool for the evaluation of brain function, even in the context of COVID-19. However, EEG technologists should not be put in danger if obtaining an EEG does not significantly advance diagnosis or change management in the patient. Not every neurologic problem stems from a primary brain injury: confusion, impaired consciousness that evolves to stupor and coma, and headaches are frequent in hypercapnic/hypoxic encephalopathies. In patients with chronic pulmonary disorders, acute symptomatic ...
Source: Clinical Neurophysiology - May 13, 2020 Category: Neurology Authors: Gelisse P, Rossetti AO, Genton P, Crespel A, Kaplan PW Tags: Clin Neurophysiol Source Type: research

Investigating the influence of paired-associative stimulation on multi-session skill acquisition and retention in older adults.
CONCLUSIONS: PASLTD over multiple sessions may represent an effective tool to help maintain newly learned motor skills in older adults. SIGNIFICANCE: While multisession priming with PAS can influence long-term skill retention, improving skill acquisition requires investigation of alternative protocols. PMID: 32388475 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - April 30, 2020 Category: Neurology Authors: Opie GM, Pourmajidian M, Ziemann U, Semmler JG Tags: Clin Neurophysiol Source Type: research

EEG during the COVID-19 pandemic: What remains the same and what is different.
PMID: 32388156 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - April 25, 2020 Category: Neurology Authors: Sethi NK Tags: Clin Neurophysiol Source Type: research

Different findings of morphological changes and functional decline in the vestibule and the semicircular canal in ipsilateral delayed endolymphatic hydrops.
CONCLUSIONS: Hydrops can be found mainly in the vestibule as shown by MRI. In the vestibule, abnormalities are commonly morphologic rather than functional, whereas in the LSCC a functional deterioration can be detected more frequently than morphological changes. SIGNIFICANCE: Our findings can provide a new perspective on the functional and morphological characteristics of patients with DEH. PMID: 32388473 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - April 23, 2020 Category: Neurology Authors: Yu J, Zhou YJ, Xu XD, Tian L, Ren DD, Ding CR, Wang J, Chi FL Tags: Clin Neurophysiol Source Type: research

The clinical meaning of giant somatosensory evoked potentials of the median nerve.
WN PMID: 32388474 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - April 23, 2020 Category: Neurology Authors: Horlings CGC, Kofler M, Hotter A, Reiter E, Wanschitz JV, Löscher WN Tags: Clin Neurophysiol Source Type: research

Does EMG provide essential information for the diagnosis and treatment of blepharospasm?
PMID: 32387048 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - April 21, 2020 Category: Neurology Authors: Conte A, Ferrazzano G, Berardelli A Tags: Clin Neurophysiol Source Type: research

A proposal for new diagnostic criteria for ALS.
nan MC PMID: 32387049 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - April 19, 2020 Category: Neurology Authors: Shefner JM, Al-Chalabi A, Baker MR, Cui LY, de Carvalho M, Eisen A, Grosskreutz J, Hardiman O, Henderson R, Manuel Matamala J, Mitsumoto H, Paulus W, Simon N, Swash M, Talbot K, Turner MR, Ugawa Y, van den Berg LH, Verdugo R, Vucic S, Kaji R, Burke D, Kie Tags: Clin Neurophysiol Source Type: research

Reply to "Electrophysiology and ultrasonography in the diagnosis of ulnar neuropathy at the elbow".
Reply to "Electrophysiology and ultrasonography in the diagnosis of ulnar neuropathy at the elbow". Clin Neurophysiol. 2020 Apr 17;: Authors: Podnar S, Omejec G PMID: 32349940 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - April 17, 2020 Category: Neurology Authors: Podnar S, Omejec G Tags: Clin Neurophysiol Source Type: research

Electrophysiology and ultrasonography in the diagnosis of ulnar neuropathy at the elbow.
PMID: 32345517 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - April 16, 2020 Category: Neurology Authors: Pelosi L, Mulroy E Tags: Clin Neurophysiol Source Type: research

Peripheral nerve imaging in amyotrophic lateral sclerosis.
Abstract We systematically identified and reviewed 29 studies of peripheral nerve ultrasound or magnetic resonance imaging (MRN) in amyotrophic lateral sclerosis (ALS). The majority of the ultrasound studies reported smaller nerves and nerve roots in ALS compared to healthy controls, but there was a large overlap of the cross-sectional nerve area between ALS and controls. Most of the MRN studies confirmed nerve abnormalities demonstrating slight T2 hyperintensities and, sometimes, mild enlargement of more proximal nerve segments (plexus, roots) in ALS. The size of the proximal nerve segments, i.e. nerve roots, is ...
Source: Clinical Neurophysiology - April 13, 2020 Category: Neurology Authors: Schreiber S, Vielhaber S, Schreiber F, Cartwright MS Tags: Clin Neurophysiol Source Type: research

Interrogating interneurone function using threshold tracking of the H reflex in healthy subjects and patients with motor neurone disease.
CONCLUSIONS: Threshold tracking is useful and may be preferable under some conditions for studying the excitability of the motoneurone pool. The decreased D1 inhibition in the patients suggests that presynaptic inhibition may be reduced in MND. SIGNIFICANCE: Reduced presynaptic inhibition could be evidence of an interneuronopathy in MND. It is possible that the hyperreflexia is a spinal pre-motoneuronal disorder, and not definitive evidence of corticospinal involvement in MND. PMID: 32336595 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - April 13, 2020 Category: Neurology Authors: Howells J, Sangari S, Matamala JM, Kiernan MC, Marchand-Pauvert V, Burke D Tags: Clin Neurophysiol Source Type: research

Evidence for normative intracortical inhibitory recruitment properties in cervical dystonia.
This study evaluated cSP recruitment properties in people with cervical dystonia (CD). METHODS: Bilateral electromyographic recordings were collected in the upper trapezius muscle in response to transcranial magnetic stimulation of the left and right primary motor cortex in a group with CD (n = 19) and controls (n = 21). cSP threshold, cSP input-output properties at stimulation intensities from 1 to 1.4x the cSP threshold, ipsilateral silent period duration (iSP) and timing and magnitude of the contralateral and ipsilateral motor evoked potential (MEP) were assessed. RESULTS: The cSP threshold...
Source: Clinical Neurophysiology - April 2, 2020 Category: Neurology Authors: Summers RLS, Chen M, MacKinnon CD, Kimberley TJ Tags: Clin Neurophysiol Source Type: research

Modulation of self-appraisal of illness, medication adherence, life quality and autonomic functioning by transcranial direct current stimulation in schizophrenia patients.
Abstract OBJECTIVES: Little is known about the impact of fronto-temporal transcranial direct current stimulation (tDCS) on attitudes toward mental illness, psychosocial and autonomic functioning, life quality, and medication adherence among schizophrenia patients. METHODS: Sixty schizophrenia patients were randomly allocated to receive 10 sessions of active (2 mA, 20 min, 2 sessions/day for five weekdays) or sham fronto-temporal tDCS. Self-Appraisal of Illness Questionnaire (SAIQ), Medication Adherence Rating Scale (MARS), World Health Organization Quality of Life-BREF (WHOQOL-BREF) and indices of h...
Source: Clinical Neurophysiology - April 2, 2020 Category: Neurology Authors: Kao YC, Tzeng NS, Chao CY, Chang CC, Chang HA Tags: Clin Neurophysiol Source Type: research

Electrophysiological and phenotypic profiles of taxane-induced neuropathy.
CONCLUSIONS: There is considerable variation in CIPN phenotypes associated with taxane-treatment. Understanding their clinical associations may assist in identification of patients at risk of severe neurotoxicity. This would enable treatment modification decisions but also limit early cessation of effective anti-cancer treatment in patients with less severe neurological sequelae. SIGNIFICANCE: Understanding the CIPN phenotype may inform treatment decisions which could impact clinical and survival outcomes. PMID: 32291143 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - April 2, 2020 Category: Neurology Authors: Timmins HC, Li T, Huynh W, Kiernan MC, Baron-Hay S, Boyle F, Goldstein D, Park SB Tags: Clin Neurophysiol Source Type: research

An artificial intelligence-based EEG algorithm for detection of epileptiform EEG discharges: Validation against the diagnostic gold standard.
CONCLUSIONS: Automated detection of EDs using an artificial intelligence-based computer algorithm had a high sensitivity. Human (expert) supervision is still necessary for confirming the clusters of detected EDs and for describing clinical correlations. Further studies on different patient populations will be needed to confirm our results. SIGNIFICANCE: The automated algorithm we describe here is a useful tool, assisting neurophysiologist in rapid assessment of EEG recordings. PMID: 32299000 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - April 2, 2020 Category: Neurology Authors: Fürbass F, Kural MA, Gritsch G, Hartmann M, Kluge T, Beniczky S Tags: Clin Neurophysiol Source Type: research

GRM8 genotype is associated with externalizing disorders and greater inter-trial variability in brain activation during a response inhibition task.
CONCLUSIONS: GRM8 genotype is associated with Alcohol and Cocaine Dependence as well as personality risk factors for dependence. The association may be mediated through an inherited instability in brain function that affects cognitive control. SIGNIFICANCE: The present study focuses on a metric and brain mechanism not typically considered or theorized in studies of patients with substance use disorders. PMID: 32299001 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - April 2, 2020 Category: Neurology Authors: Bauer LO, Covault JM Tags: Clin Neurophysiol Source Type: research

Automatic detection of cortical arousals in sleep and their contribution to daytime sleepiness.
CONCLUSIONS: The MAD performed better or comparable to human expert scorers. The MAD-predicted arousals were shown to be significant predictors of MSL. SIGNIFICANCE: This study validates a fully automatic method for scoring arousals in PSGs. PMID: 32299002 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - April 2, 2020 Category: Neurology Authors: Brink-Kjaer A, Olesen AN, Peppard PE, Stone KL, Jennum P, Mignot E, Sorensen HBD Tags: Clin Neurophysiol Source Type: research

Pretarsal blepharospasm: Clinical and electromyographic characteristics.
CONCLUSIONS: Pretarsal blepharospasm can be suspected on clinical grounds and it can be confirmed by electromyographic recordings. SIGNIFICANCE: Recognition of this type of blepharospasm is important because of its excellent response to botulinum toxin injections applied into the pretarsal part of the orbicularis oculi muscle. PMID: 32280019 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - April 2, 2020 Category: Neurology Authors: Grandas F, Traba A, Perez-Sanchez JR, Esteban A Tags: Clin Neurophysiol Source Type: research

Reply to "Repeater F-waves detection in upper motor neuron dysfunction".
Reply to "Repeater F-waves detection in upper motor neuron dysfunction". Clin Neurophysiol. 2020 Mar 20;: Authors: Oguz Akarsu E, Sirin NG, Baslo MB, Oge AE PMID: 32245679 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - March 20, 2020 Category: Neurology Authors: Oguz Akarsu E, Sirin NG, Baslo MB, Oge AE Tags: Clin Neurophysiol Source Type: research

Repeater F-waves detection in upper motor neuron dysfunction.
PMID: 32245680 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - March 20, 2020 Category: Neurology Authors: Veltsista D, Chroni E Tags: Clin Neurophysiol Source Type: research

Threshold tracking as a tool to study activity-dependent axonal plasticity.
PMID: 32224021 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - March 17, 2020 Category: Neurology Authors: Moldovan M Tags: Clin Neurophysiol Source Type: research

Motor unit estimation by MRI: Integrating old and new ideas.
PMID: 32201104 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - March 12, 2020 Category: Neurology Authors: de Carvalho M, Swash M Tags: Clin Neurophysiol Source Type: research