Epileptic activity in neurological deterioration after ischemic stroke, a continuous EEG study.
Abstract OBJECTIVE: Despite improvement in acute stroke care, almost 40% of patients with ischemic stroke present neurological deterioration. Neurological deterioration is associated with higher death and dependency rates. Neurological deterioration mechanisms are unknown, and half of neurological deterioration remains unexplained. We postulate that a substantial proportion of neurological deterioration in ischemic stroke is associated with periodic discharges/non-convulsive seizures that negatively impact the recovery of ischemic stroke and worsen symptoms. METHODS: Retrospective review of 24 h continuous EE...
Source: Clinical Neurophysiology - September 21, 2019 Category: Neurology Authors: Scoppettuolo P, Gaspard N, Depondt C, Legros B, Ligot N, Naeije G Tags: Clin Neurophysiol Source Type: research

Saccular function is associated with both angular and distance errors on the triangle completion test.
Abstract OBJECTIVE: The present study was designed to determine whether healthy older adults with age-related vestibular loss have deficits in spatial navigation. METHODS: 154 adults participating in the Baltimore Longitudinal Study of Aging were tested for semicircular canal, saccular, and utricular function and spatial navigation ability using the blindfolded Triangle Completion Test (TCT). Multiple linear regression was used to investigate the relationships between each measure of vestibular function and performance on the TCT (angular error, end point error, and distance walked) while controlling for age ...
Source: Clinical Neurophysiology - September 17, 2019 Category: Neurology Authors: Anson ER, Ehrenburg MR, Wei EX, Bakar D, Simonsick E, Agrawal Y Tags: Clin Neurophysiol Source Type: research

Prospective observational study: Fast ripple localization delineates the epileptogenic zone.
Abstract OBJECTIVE: To investigate spatial correlation between interictal HFOs and neuroimaging abnormalities, and to determine if complete removal of prospectively identified interictal HFOs correlates with post-surgical seizure-freedom. METHODS: Interictal fast ripples (FRs: 250-500 Hz) in 19 consecutive children with pharmacoresistant focal epilepsy who underwent extra-operative electrocorticography (ECoG) recording were prospectively analyzed. The interictal FRs were sampled at 2000 Hz and were visually identified during 10 min of slow wave sleep. Interictal FRs, MRI and FDG-PET were delineated on pat...
Source: Clinical Neurophysiology - September 17, 2019 Category: Neurology Authors: Nariai H, Hussain SA, Bernardo D, Fallah A, Murata KK, Nguyen JC, Rajaraman RR, Rao LM, Matsumoto JH, Lerner JT, Salamon N, Elashoff D, Sankar R, Wu JY Tags: Clin Neurophysiol Source Type: research

What are you looking at? Unrippling terminology for high frequency activity.
PMID: 31563811 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - September 17, 2019 Category: Neurology Authors: Noorlag L, van Klink N, Huiskamp G, Zijlmans M Tags: Clin Neurophysiol Source Type: research

Photosensitive epilepsy and long QT: expanding Timothy syndrome phenotype.
PMID: 31563812 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - September 17, 2019 Category: Neurology Authors: Po' C, Zordan R, Vecchi M, Cerutti A, Sartori S, Trevisson E, Ludwig K, Castaldi B, Salviati L, Leoni L, Toldo I Tags: Clin Neurophysiol Source Type: research

Implicit learning in the developing brain: An exploration of ERP indices for developmental disorders.
PMID: 31542253 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - September 10, 2019 Category: Neurology Authors: Daikoku T Tags: Clin Neurophysiol Source Type: research

International Federation of Clinical Neurophysiology (IFCN) - EEG research workgroup: Recommendations on frequency and topographic analysis of resting state EEG rhythms. Part 1: Applications in clinical research studies.
Abstract In 1999, the International Federation of Clinical Neurophysiology (IFCN) published "IFCN Guidelines for topographic and frequency analysis of EEGs and EPs" (Nuwer et al., 1999). Here a Workgroup of IFCN experts presents unanimous recommendations on the following procedures relevant for the topographic and frequency analysis of resting state EEGs (rsEEGs) in clinical research defined as neurophysiological experimental studies carried out in neurological and psychiatric patients: (1) recording of rsEEGs (environmental conditions and instructions to participants; montage of the EEG electrodes; reco...
Source: Clinical Neurophysiology - September 6, 2019 Category: Neurology Authors: Babiloni C, Barry RJ, Başar E, Blinowska KJ, Cichocki A, Drinkenburg WHIM, Klimesch W, Knight RT, Lopes da Silva F, Nunez P, Oostenveld R, Jeong J, Pascual-Marqui R, Valdes-Sosa P, Hallett M Tags: Clin Neurophysiol Source Type: research

Relationship between EMG-detected and ultrasound-detected fasciculations in amyotrophic lateral sclerosis: A prospective cohort study.
Abstract OBJECTIVES: Fasciculation potentials (FP) are an important consideration in the electrophysiological diagnosis of ALS. Muscle ultrasonography (MUS) has a higher sensitivity in detecting fasciculations than electromyography (EMG), while in some cases, it is unable to detect EMG-detected fasciculations. We aimed to investigate the differences of FP between the muscles with and without MUS-detected fasciculations (MUS-fas). METHODS: Thirty-one consecutive patients with sporadic ALS were prospectively recruited and in those, both needle EMG and MUS were performed. Analyses of the amplitude, duration, and...
Source: Clinical Neurophysiology - August 28, 2019 Category: Neurology Authors: Bokuda K, Shimizu T, Kimura H, Morishima R, Kamiyama T, Kawata A, Nakayama Y, Isozaki E Tags: Clin Neurophysiol Source Type: research

Corrigendum to 'A pilot study on the efficacy of transcranial direct current stimulation applied to the pharyngeal motor cortex for dysphagia associated with brainstem involvement in multiple sclerosis' [Clin. Neurophysiol. 130 (2019) 1017-1024].
PMID: 31473144 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - August 28, 2019 Category: Neurology Authors: Restivo DA, Alfonsi E, Casabona A, Hamdy S, Tassorelli C, Panebianco M, Marchese-Ragona R, Quartarone A, Centonze D, Pavone A, Bassi MS Tags: Clin Neurophysiol Source Type: research

F Wave Analyzer, a system for repeater F-waves detection: Application in patients with amyotrophic lateral sclerosis.
CONCLUSION: In ALS, the high numbers of Freps, reduced overall F-wave persistence and increased F-wave amplitude measurements in a relatively unaffected nerve-muscle complex reflects excitability alterations of the corresponding motor neuron pool. Overall, automatic analysis facilitates accurate and fast detection of Freps and could be useful in other clinical settings. SIGNIFICANCE: Analysis of repeater F-waves is expected to provide new insight regarding ALS pathophysiology and utilized for monitoring in clinical drug trials. PMID: 31472478 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - August 16, 2019 Category: Neurology Authors: Veltsista D, Papapavlou C, Chroni E Tags: Clin Neurophysiol Source Type: research

Diagnostic added value of electrical source imaging in presurgical evaluation of patients with epilepsy: A prospective study.
CONCLUSIONS: ESI provides non-redundant information in one third of the patients undergoing presurgical evaluation. SIGNIFICANCE: This study provides evidence for the diagnostic added value of ESI in presurgical evaluation. PMID: 31466846 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - August 16, 2019 Category: Neurology Authors: Foged MT, Martens T, Pinborg LH, Hamrouni N, Litman M, Rubboli G, Leffers AM, Ryvlin P, Jespersen B, Paulson OB, Fabricius M, Beniczky S Tags: Clin Neurophysiol Source Type: research

Auditory gating in adults with dyslexia: An ERP account of diminished rapid neural adaptation.
CONCLUSIONS: Neural adaptation occurs by approximately 100 ms after stimulus presentation and is diminished in adults with dyslexia. This complements fMRI findings of relevant brain regions by implying a time window representing sensory and pre-attentive auditory processes. SIGNIFICANCE: The association between gating magnitude and word discrimination contributes to a neurophysiological account of underspecified word representations. PMID: 31451333 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - August 12, 2019 Category: Neurology Authors: Peter B, McCollum H, Daliri A, Panagiotides H Tags: Clin Neurophysiol Source Type: research

Lack of evidence for interhemispheric inhibition in the lower face primary motor cortex.
CONCLUSION: In the DAO there was no evidence of IHI even though this was clear in hand and axial muscles. Control experiments excluded a transcallosal origin of the facilitation observed at the shortest intervals. SIGNIFICANCE: Data suggest that integrated bilateral control of facial muscles occurs mainly at the level of brainstem circuits engaged by corticobulbar output from fM1. PMID: 31437744 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - August 8, 2019 Category: Neurology Authors: Ginatempo F, Manzo N, Rothwell JC, Deriu F Tags: Clin Neurophysiol Source Type: research

A new potential specifically marks the sensory thalamus in anaesthetised patients.
CONCLUSIONS: VHFOs are widely extending and cannot be ascribed to the V.c. HFOs in patients under general anaesthesia can serve as a landmark to identify the V.c. in thalamic DBS surgery. SIGNIFICANCE: Thalamic processing involves nuclei other than the V.c, and HFO can be used to improve DBS surgery. PMID: 31437745 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - August 8, 2019 Category: Neurology Authors: Pastor J, Vega-Zelaya L Tags: Clin Neurophysiol Source Type: research

Motor unit number index (MUNIX) and compound muscle action potential amplitude: A reappraisal.
g EV PMID: 31416706 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - July 31, 2019 Category: Neurology Authors: Nandedkar SD, Barkhaus PE, Stålberg EV Tags: Clin Neurophysiol Source Type: research

Reply to "Motor Unit Number Index (MUNIX) and Compound Muscle Action Potential".
Reply to "Motor Unit Number Index (MUNIX) and Compound Muscle Action Potential". Clin Neurophysiol. 2019 Jul 31;: Authors: Bostock H, Jacobsen AB, Tankisi H PMID: 31409557 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - July 31, 2019 Category: Neurology Authors: Bostock H, Jacobsen AB, Tankisi H Tags: Clin Neurophysiol Source Type: research

Oscillatory connectivity as a diagnostic marker of dementia due to Alzheimer's disease.
CONCLUSIONS: The diagnostic accuracies for EEG connectivity measures are higher than findings from studies investigating EEG power and conventional Alzheimer's disease biomarkers. Furthermore, decreased alpha coherence is one of the earliest changes in Alzheimer's disease and associated with memory function. SIGNIFICANCE: EEG connectivity measures may be useful supplementary diagnostic classifiers. PMID: 31408790 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - July 29, 2019 Category: Neurology Authors: Musaeus CS, Engedal K, Høgh P, Jelic V, Mørup M, Naik M, Oeksengaard AR, Snaedal J, Wahlund LO, Waldemar G, Andersen BB Tags: Clin Neurophysiol Source Type: research

Can theta burst stimulation safely influence auditory hearing thresholds in healthy young adults?
CONCLUSIONS: A single stimulation session led to an effective neuromodulation of the auditory cortex, reflected in lower thresholds when using iTBS. SIGNIFICANCE: These encouraging results with this safe noninvasive tool suggest that iTBS may have the potential to positively influence hearing thresholds. PMID: 31408791 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - July 29, 2019 Category: Neurology Authors: Pinto N, Oliveira I, Ferreira J, Gama J, Vaz Pato M Tags: Clin Neurophysiol Source Type: research

Stability of a chronic implanted brain-computer interface in late-stage amyotrophic lateral sclerosis.
CONCLUSIONS: The implanted brain-computer interface proves to be robust in an individual with late-stage ALS, given stable performance and control signal for over 36 months. SIGNIFICANCE: These findings are relevant for the future of implantable brain-computer interfaces along with other brain-sensing technologies, such as responsive neurostimulation. PMID: 31401488 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - July 27, 2019 Category: Neurology Authors: Pels EGM, Aarnoutse EJ, Leinders S, Freudenburg ZV, Branco MP, van der Vijgh BH, Snijders TJ, Denison T, Vansteensel MJ, Ramsey NF Tags: Clin Neurophysiol Source Type: research

Frequency and characteristic features of REM sleep without atonia.
CONCLUSIONS: RSWA is a frequent finding in the context of antidepressant use or synucleinopathies. iRSWA subjects reported increased excessive daytime sleepiness and more often had excessive daytime sleepiness as polysomnography indication. SIGNIFICANCE: Our study provides evidence for high frequency of RSWA, underscoring the need for longitudinal studies in iRSWA patients, with interest for conversion to synucleinopathies. PMID: 31401491 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - July 27, 2019 Category: Neurology Authors: Dijkstra F, Viaene M, Crosiers D, De Volder I, Cras P Tags: Clin Neurophysiol Source Type: research

EEG reactivity predicts recovery of consciousness in patients with acute brain injury and signs of intracranial hypertension.
PMID: 31400576 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - July 26, 2019 Category: Neurology Authors: Longhi L, Cavalleri G, Ferri F, Lorini L, Zangari R, Rottoli MR, Frigeni B Tags: Clin Neurophysiol Source Type: research

Reply to "Transcutaneous electric currents to target the peripheral and central nervous system in children with attention deficit hyperactivity disorder".
Reply to "Transcutaneous electric currents to target the peripheral and central nervous system in children with attention deficit hyperactivity disorder". Clin Neurophysiol. 2019 Jul 23;: Authors: McGough JJ, Loo SK, Cook IA PMID: 31377119 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - July 23, 2019 Category: Neurology Authors: McGough JJ, Loo SK, Cook IA Tags: Clin Neurophysiol Source Type: research

Transcutaneous electric currents to target the peripheral and central nervous system in children with attention deficit hyperactivity disorder.
PMID: 31377120 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - July 23, 2019 Category: Neurology Authors: Schutter DJLG, Hunnius S, Rommelse N Tags: Clin Neurophysiol Source Type: research

Current source density approaches improve spatial resolution in event related potential analysis in people with Parkinson's disease.
PMID: 31377118 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - July 22, 2019 Category: Neurology Authors: Fearon C, Butler JS, Waechter SM, Killane I, Reilly RB, Lynch T Tags: Clin Neurophysiol Source Type: research

Unforeseen clinical outcome for laryngeal adductor reflex loss during intraaxial brainstem surgery.
Sinclair CF, Ulkatan S PMID: 31371238 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - July 19, 2019 Category: Neurology Authors: Pescador AM, Ángeles Sánchez Roldán M, Téllez MJ, Sinclair CF, Ulkatan S Tags: Clin Neurophysiol Source Type: research

Reply to "Current source density approaches improve spatial resolution in event related potential analysis in people with Parkinson's disease".
Reply to "Current source density approaches improve spatial resolution in event related potential analysis in people with Parkinson's disease". Clin Neurophysiol. 2019 Jul 19;: Authors: Maidan I PMID: 31353268 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - July 19, 2019 Category: Neurology Authors: Maidan I Tags: Clin Neurophysiol Source Type: research

Alpha oscillations and consciousness in completely locked-in state.
PMID: 31330450 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - July 15, 2019 Category: Neurology Authors: Rosburg T Tags: Clin Neurophysiol Source Type: research

Long-term impact of prenatal exposure to chemotherapy on executive functioning: An ERP study.
This study examines the long-term impact of prenatal exposure to chemotherapy on executive functioning and the contribution of late-prematurity to this effect, using event-related potentials. METHODS: Mothers of the prenatal-exposed children (n = 20) were diagnosed with cancer and received chemotherapeutic treatment during pregnancy. We recruited healthy controls (n = 20) who were matched on a 1:1 ratio regarding prematurity, age and sex. We assessed executive functioning at the age of nine, using two event-related potential paradigms: a Go/Nogo paradigm to investigate processes of response inhibition and conf...
Source: Clinical Neurophysiology - July 9, 2019 Category: Neurology Authors: Blommaert J, Zink R, Deprez S, Myatchin I, Dupont P, Vandenbroucke T, Sleurs C, Van Calsteren K, Amant F, Lagae L Tags: Clin Neurophysiol Source Type: research

Unravelling mechanisms of altered modulation of trigemino-facial circuits in blepharospasm.
PMID: 31326645 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - July 9, 2019 Category: Neurology Authors: Baione V, Ferrazzano G, Berardelli I, Belvisi D, Berardelli A, Conte A Tags: Clin Neurophysiol Source Type: research

Is Motor Unit Number Index (MUNIX) an index of Compound Muscle Action Potential amplitude rather than motor unit number?
PMID: 31303432 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - July 4, 2019 Category: Neurology Authors: Moldovan M, Vucic S Tags: Clin Neurophysiol Source Type: research

Nocturnal motor events in epilepsy: Is there a defined physiological network?
CONCLUSION: We conclude that nocturnal movements are due to a complex interplay within this physiological network of defined anatomical regions. Epileptic activity had significant impact on nocturnal movements but was not required for generation. SIGNIFICANCE: Where the semiology of the first clinical sign of a seizure consistently matches a patient's nocturnal movements, we suggest that the underlying epileptogenic zone is potentially located within this defined network. PMID: 31299588 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - July 2, 2019 Category: Neurology Authors: Woolfe M, Prime D, Tjoa L, O'Keefe S, Rowlands D, Dionisio S Tags: Clin Neurophysiol Source Type: research

Sleep deprivation and Modafinil affect cortical sources of resting state electroencephalographic rhythms in healthy young adults.
CONCLUSIONS: The present results suggest that posterior delta and alpha source activities may be both related to the regulation of human brain arousal and vigilance in quiet wakefulness. SIGNIFICANCE: Future research in healthy young adults may use this methodology to preselect new symptomatic drug candidates designed to normalize brain arousal and vigilance in seniors with dementia. PMID: 31295717 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - July 1, 2019 Category: Neurology Authors: Del Percio C, Derambure P, Noce G, Lizio R, Faz DB, Blin O, Payoux P, Deplanque D, Méligne D, Chauveau N, Bourriez JL, Casse-Perrot C, Lanteaume L, Thalamas C, Dukart J, Ferri R, Pascarelli MT, Richardson JC, Bordet R, Babiloni C, PharmaCog Consortium Tags: Clin Neurophysiol Source Type: research

Picking up the pace.
PMID: 31295722 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - June 25, 2019 Category: Neurology Authors: Marafi D, Fussner S, Chen YY, Yoshor D, Van Ness P, Maheshwari A Tags: Clin Neurophysiol Source Type: research

Artificial intelligence in the field of electrodiagnosis - A new threat or heralding a new era in electromyography?
PMID: 31257119 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - June 24, 2019 Category: Neurology Authors: Jeon J, Han YJ, Park GY, Sohn DG, Lee S, Im S Tags: Clin Neurophysiol Source Type: research

Reply to "Artificial intelligence in the field of electrodiagnosis - A new threat or heralding a new era in electromyography?"
Reply to "Artificial intelligence in the field of electrodiagnosis - A new threat or heralding a new era in electromyography?" Clin Neurophysiol. 2019 Jun 24;: Authors: Nodera H PMID: 31255423 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - June 24, 2019 Category: Neurology Authors: Nodera H Tags: Clin Neurophysiol Source Type: research

The 'neurophysiological index' predicts survival in amyotrophic lateral sclerosis.
PMID: 31213354 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - June 11, 2019 Category: Neurology Authors: Swash M, de Carvalho M Tags: Clin Neurophysiol Source Type: research

Standards for quantification of EMG and neurography.
ts M Abstract This document is an update and extension of ICCN Standards published in 1999. It is the consensus of experts on the current status of EMG and Neurography methods. A panel of authors from different countries with different approach to routines in neurophysiological methods was chosen based on their particular interest and previous publications. Each member of the panel submitted a section on their particular area of interest and these submissions were circulated among the panel members for edits and comments. This process continued until a consensus was reached. The document covers EMG topics such as ...
Source: Clinical Neurophysiology - June 10, 2019 Category: Neurology Authors: Stålberg E, van Dijk H, Falck B, Kimura J, Neuwirth C, Pitt M, Podnar S, Rubin DI, Rutkove S, Sanders DB, Sonoo M, Tankisi H, Zwarts M Tags: Clin Neurophysiol Source Type: research

It twitches without kicking - An association between fragmentary myoclonus and arousal?
CONCLUSIONS: We suggest FM represents a ubiquitous motor phenomenon occurring spontaneously during relaxed wakefulness and sleep, primarily in men and with advanced age. SIGNIFICANCE: In women, particularly FMI25 may be a surrogate marker for more frequent arousals and sleep fragmentation. PMID: 31212201 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - June 1, 2019 Category: Neurology Authors: Trimmel K, Lindinger G, Böck M, Stefanic A, Klösch G, Seidel S Tags: Clin Neurophysiol Source Type: research

Quantitative electrocorticographic biomarkers of clinical outcomes in mesial temporal lobe epileptic patients treated with the RNS ® system.
Quantitative electrocorticographic biomarkers of clinical outcomes in mesial temporal lobe epileptic patients treated with the RNS® system. Clin Neurophysiol. 2019 May 31;130(8):1364-1374 Authors: Arcot Desai S, Tcheng TK, Morrell MJ Abstract OBJECTIVES: Find interictal electrocorticographic (ECoG) biomarkers of clinical outcomes in mesiotemporal lobe (MTL) epilepsy patients. METHODS: In the NeuroPace® RNS® System clinical trials with 256 patients, 20 MTL patients with the most reduction in clinical seizures at Year 7 compared to baseline (upper response quartile; -96.5% median change...
Source: Clinical Neurophysiology - May 31, 2019 Category: Neurology Authors: Arcot Desai S, Tcheng TK, Morrell MJ Tags: Clin Neurophysiol Source Type: research

Phonemes, words, and phrases: Tracking phonological processing in pre-schoolers developing dyslexia.
CONCLUSION: Our findings complement the picture of phonological processing in dyslexia by confirming difficulties in segmental phonology and showing that prosodic processing is affected for the smaller word level, but not the larger phrase level. SIGNIFICANCE: These findings might have implications for early interventions, considering both phonemic awareness and stress pattern training. PMID: 31200240 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - May 31, 2019 Category: Neurology Authors: Schaadt G, Männel C Tags: Clin Neurophysiol Source Type: research

Periodic focal epileptiform discharges.
Abstract OBJECTIVE: To report intraoperative periodic focal epileptiform discharges (PFEDs) during awake craniotomy using high-density electrocorticography (HD-ECoG). METHODS: We retrospectively analyzed 81 patients undergoing awake craniotomy between 9/29/2016 and 7/5/2018. Intraoperative HD-ECoG was performed with direct electrocortical stimulation (DECS) for functional brain mapping. Real-time interpretation was performed and compared to scalp EEG when performed. Perioperative seizures, surgical complications, and characteristics of PFEDs were assessed. RESULTS: 69/81 patients (mean age 48.5 years) ...
Source: Clinical Neurophysiology - May 31, 2019 Category: Neurology Authors: Tatum WO, Feyissa AM, ReFaey K, Grewal SS, Alvi MA, Castro-Apolo R, Roth G, Segura-Duran I, Mahato D, Ruiz-Garcia H, Pamias-Portalatin E, Yelvington K, Chaichana K, Bechtle P, Quinones-Hinojosa A Tags: Clin Neurophysiol Source Type: research

The influence of one session of low frequency rTMS on pre-supplementary motor area metabolites in late stage Parkinson's disease.
CONCLUSIONS: LF rTMS at the right pre-SMA in late stage Parkinson's disease patients does not alter tNAA/tCr, but influences tCho/tCr ratio, in particular in patients with shorter disease duration. SIGNIFICANCE: Pre-SMA LF rTMS seems to influence membrane turnover, more importantly in patients with shorter disease duration. Larger LF rTMS treatment studies applying multiple sessions are needed. PMID: 31176928 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - May 31, 2019 Category: Neurology Authors: Flamez A, Wiels W, Van Schuerbeek P, De Mey J, De Keyser J, Baeken C Tags: Clin Neurophysiol Source Type: research

Hyperreflexia as an upper motor neuron sign in amyotrophic lateral sclerosis.
PMID: 31171431 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - May 30, 2019 Category: Neurology Authors: Burke D Tags: Clin Neurophysiol Source Type: research

A new diagnostic tool for the detection of steroid myopathy.
PMID: 31171432 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - May 30, 2019 Category: Neurology Authors: Simon NG Tags: Clin Neurophysiol Source Type: research

High frequency oscillations (HFOs) as a unique pattern of EEG in a patient with anti-NMDA receptor encephalitis.
PMID: 31163367 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - May 27, 2019 Category: Neurology Authors: Wang T, Mayson DJ, Tornatore CS, Motamedi GK Tags: Clin Neurophysiol Source Type: research

Incorporation of fixation-removal with Fresnel glasses in a routine EEG protocol.
PMID: 31163362 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - May 24, 2019 Category: Neurology Authors: Alhajaj G, Myers KA Tags: Clin Neurophysiol Source Type: research

Neurophysiological evidence of impaired attention and working memory in untreated hematologic cancer patients.
Abstract OBJECTIVE: Neuroimaging studies of hematologic cancer patients report altered activity in dorsal attention and central executive networks. To determine the consequences of these altered brain networks, we evaluated neurophysiological correlates of attention and working memory in hematologic cancer patients prior to initiating treatment. METHODS: Hematologic cancer patients (19-80 years) were excluded for premorbid cognitive impairment, prior non-hematologic cancer diagnosis, and prior chemotherapy. Attention was manipulated by presenting an irrelevant spatial cue prior to visual search displays. Wo...
Source: Clinical Neurophysiology - May 24, 2019 Category: Neurology Authors: Anderson DE, Bhatt VR, Schmid K, Holstein SA, Lunning M, Berger AM, Rizzo M Tags: Clin Neurophysiol Source Type: research

MScanFit motor unit number estimation (MScan) and muscle velocity recovery cycle recordings in amyotrophic lateral sclerosis patients.
CONCLUSION: MScanFit MUNE gives a sensitive and quantitative measure of loss of TA motor units in ALS. Muscle fiber membrane properties are mostly unaffected, despite substantial denervation, presumably due to collateral reinnervation. SIGNIFICANCE: MScan is suitable for detecting motor unit loss in TA. MVRCs do not provide new insights in ALS. PMID: 31163374 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - May 24, 2019 Category: Neurology Authors: Kristensen RS, Bostock H, Tan SV, Witt A, Fuglsang-Frederiksen A, Qerama E, Andersen H, Tankisi H Tags: Clin Neurophysiol Source Type: research

Effect of repetitive transcranial magnetic stimulation combined with robot-assisted training on wrist muscle activation post-stroke.
CONCLUSIONS: Following a single rTMS + RW session in people>1-year post-stroke, changes were found in voluntary muscle activation of wrist extensor muscles. Alterations in ipsilesional corticospinal or interhemispheric excitability were not detected. SIGNIFICANCE: The effects of rTMS + RW on muscle activation warrant further investigation as post-stroke rehabilitation strategy. PMID: 31163373 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - May 20, 2019 Category: Neurology Authors: Miller KJ, Gallina A, Neva JL, Ivanova TD, Snow NJ, Ledwell NM, Xiao ZG, Menon C, Boyd LA, Garland SJ Tags: Clin Neurophysiol Source Type: research

Not all brain regions are created equal for improving bimanual coordination in individuals with chronic stroke.
CONCLUSIONS: Cortical stimulation protocols could be tailored to the types of tasks and to individuals' severity of impairment. Facilitation of cPMd may improve bimanual coordination especially for individuals with limited arm/hand function. SIGNIFICANCE: Our study is the first to identify cortical stimulation strategies for improving bimanual coordination for individuals with different level of severity of stroke. PMID: 31163366 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - May 13, 2019 Category: Neurology Authors: Liao WW, Whitall J, Wittenberg GF, Barton JE, McCombe Waller S Tags: Clin Neurophysiol Source Type: research