Altered peripheral nerve excitability depends on severity of multiple sclerosis.
PMID: 31813829 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - November 27, 2019 Category: Neurology Authors: Cheung E, Parratt J, Frith J, Burke D, Ng K Tags: Clin Neurophysiol Source Type: research

Computational modelling in source space from scalp EEG to inform presurgical evaluation of epilepsy.
CONCLUSIONS: Our results show promise for the use of this framework to better interrogate scalp EEG to determine epilepsy lateralization. SIGNIFICANCE: The framework may aid clinicians in the decision process to define where to implant electrodes for intracranial monitoring. PMID: 31812920 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - November 22, 2019 Category: Neurology Authors: Lopes MA, Junges L, Tait L, Terry JR, Abela E, Richardson MP, Goodfellow M Tags: Clin Neurophysiol Source Type: research

Tripolar concentric EEG electrodes reduce noise.
Abstract OBJECTIVE: To assay EEG signal quality recorded with tripolar concentric ring electrodes (TCREs) compared to regular EEG electrodes. METHODS: EEG segments were recorded simultaneously by TCREs and regular electrodes, low-pass filtered at 35 Hz (REG35) and 70 Hz (REG70). Clips were rated blindly by nine electroencephalographers for presence or absence of key EEG features, relative to the "gold-standard" of the clinical report. RESULTS: TCRE showed less EMG artifact (F = 15.4, p 
Source: Clinical Neurophysiology - November 22, 2019 Category: Neurology Authors: Aghaei-Lasboo A, Inoyama K, Fogarty AS, Kuo J, Meador KJ, Walter JJ, Le ST, Graber KD, Razavi B, Fisher RS Tags: Clin Neurophysiol Source Type: research

A skew-based method for identifying intracranial EEG channels with epileptic activity without detecting spikes, ripples, or fast ripples.
CONCLUSIONS: The 'skew method' can distinguish epileptic from non-epileptic channels with good accuracy and, in particular, high specificity. SIGNIFICANCE: This is an easy-to-apply method that circumvents the need to visually mark or automatically detect interictal epileptic events. PMID: 31805492 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - November 22, 2019 Category: Neurology Authors: Mooij AH, Frauscher B, Gotman J, Huiskamp GJM Tags: Clin Neurophysiol Source Type: research

Influence of reference electrode position on the compound muscle action potential.
CONCLUSION: A proximal E2 position records a lower volume conducted signal and yields a CMAP that is more representative of the muscle over which the E1 (active) electrode is placed. SIGNIFICANCE: The proposed 'Proximal E2' montage may be better suited to assess pathology. PMID: 31794957 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - November 22, 2019 Category: Neurology Authors: Nandedkar SD, Barkhaus PE Tags: Clin Neurophysiol Source Type: research

Deriving pediatric nerve conduction normal values in the very young ( < 3 years).
Deriving pediatric nerve conduction normal values in the very young (
Source: Clinical Neurophysiology - November 22, 2019 Category: Neurology Authors: Jabre JF, Pitt MC, Smith R Tags: Clin Neurophysiol Source Type: research

Technology in context: A holistic care approach.
PMID: 31791924 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - November 21, 2019 Category: Neurology Authors: Lavrador JP, Patel S, Gullan R, Bhangoo R, Vergani F, Ashkan K Tags: Clin Neurophysiol Source Type: research

Effects of ventral intermediate nucleus deep brain stimulation across multiple effectors in essential tremor.
CONCLUSIONS: VIM-DBS reduced tremor in ET patients. There was no significant difference in the degree of tremor reduction across the measured effectors. SIGNIFICANCE: This study provides new quantitative evidence that VIM-DBS is effective at reducing tremor across multiple parts of the body. PMID: 31794958 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - November 20, 2019 Category: Neurology Authors: Wilkes BJ, Wagle Shukla A, Casamento-Moran A, Hess CW, Christou EA, Okun MS, Vaillancourt DE Tags: Clin Neurophysiol Source Type: research

Neurophysiological markers of cue reactivity and inhibition subtend a three-month period of complete alcohol abstinence.
CONCLUSIONS: Specific cue-reactivity and inhibitory neurophysiological markers subtend a further three-months of complete abstinence. SIGNIFICANCE: Monitoring these ERP changes during detoxification may provide important clues regarding patients' future abstinence vs. relapse. PMID: 31786051 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - November 20, 2019 Category: Neurology Authors: Campanella S, Schroder E, Kajosch H, Hanak C, Veeser J, Amiot M, Besse-Hammer T, Hayef N, Kornreich C Tags: Clin Neurophysiol Source Type: research

Acute onset and severe manifestation of postural orthostatic tachycardia syndrome - Two cases.
b M PMID: 31778914 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - November 11, 2019 Category: Neurology Authors: Chung HY, Essig F, Wickel J, Besteher B, Neugebauer H, Haeusler KG, Müllges W, Schwab M Tags: Clin Neurophysiol Source Type: research

Mapping short-latency cortical responses to electrical stimulation of thalamic motor nuclei by increasing sampling rate - A technical report.
PMID: 31765977 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - November 11, 2019 Category: Neurology Authors: Toth E, Chaitanya G, Pati S Tags: Clin Neurophysiol Source Type: research

Association of corneal nerve loss with markers of axonal ion channel dysfunction in type 1 diabetes.
Abstract OBJECTIVE: Corneal confocal microscopy (CCM) has been identified as a non-invasive technique to assess corneal nerve fiber morphology. It is not known how corneal nerve changes relate to measures of peripheral nerve function in diabetic peripheral neuropathy (DPN). The present study investigates the relationship between nerve structure and function in DPN. METHODS: Fifty participants with type 1 diabetes (T1DM) and 29 healthy controls underwent CCM to assess corneal nerve fiber density (CNFD), branch density (CNBD), fiber length (CNFL), total branch density (CTBD), nerve fractal dimension (CNFrD) and...
Source: Clinical Neurophysiology - November 11, 2019 Category: Neurology Authors: Tummanapalli SS, Issar T, Kwai N, Poynten A, Krishnan AV, Willcox M, Markoulli M Tags: Clin Neurophysiol Source Type: research

Prognostic value of phrenic nerve conduction study in amyotrophic lateral sclerosis: Systematic review and meta-analysis.
CONCLUSIONS: There is moderate-quality evidence that CMAP-amplitude of the PNC is correlated with FVC. Results favour a predictive value for mortality, but the risk of bias is high. SIGNIFICANCE: PNC is a simple test that should be considered to assess respiratory function in ALS, especially in patients with bulbar involvement or cognitive impairment. PMID: 31760209 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - November 11, 2019 Category: Neurology Authors: Silva CS, Rodrigues FB, Duarte GS, Costa J, de Carvalho M Tags: Clin Neurophysiol Source Type: research

Could we have missed out the seizure onset: A study based on intracranial EEG.
CONCLUSIONS: The signals associated with onset and spread regions exhibit different characteristics. The proposed features are able to classify the signals with good accuracy. SIGNIFICANCE: Using our classifier on new seizures could help clinicians gain confidence in having recorded the real seizure onset or on the contrary be concerned that the true onset may have been missed. PMID: 31760210 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - November 11, 2019 Category: Neurology Authors: Karthick PA, Tanaka H, Khoo HM, Gotman J Tags: Clin Neurophysiol Source Type: research

Direct cortical stimulation with cylindrical depth electrodes in the interhemispheric fissure for leg motor evoked potential monitoring.
CONCLUSIONS: Lower extremity MEPs were consistently recorded using a multi-contact cylindrical depth electrode in the interhemispheric fissure by DCS. SIGNIFICANCE: Cylindrical depth electrodes may be a safe and effective alternative for DCS in the interhemispheric fissure, where subdural strips are difficult to place. PMID: 31760211 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - November 11, 2019 Category: Neurology Authors: Brage L, Javier Pérez-Lorensu P, Plata-Bello J, Saponaro-González Á, Pérez-Orribo L, García-Conde M, Febles-García P, Roldán-Delgado H, García-Marín V Tags: Clin Neurophysiol Source Type: research

Detection of mesial temporal lobe epileptiform discharges on intracranial electrodes using deep learning.
CONCLUSIONS: Using deep learning, we developed a high-performing, patient non-specific algorithm for detection of mTL epileptiform discharges on intracranial electrodes. SIGNIFICANCE: Our algorithm has many potential applications for understanding the impact of mTL epileptiform discharges in epilepsy and on cognition, and for developing therapies to specifically reduce mTL epileptiform activity. PMID: 31760212 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - November 11, 2019 Category: Neurology Authors: Abou Jaoude M, Jing J, Sun H, Jacobs CS, Pellerin KR, Westover MB, Cash SS, Lam AD Tags: Clin Neurophysiol Source Type: research

Repeater F-waves in amyotrophic lateral sclerosis: Electrophysiologic indicators of upper or lower motor neuron involvement?
CONCLUSION: Our findings suggest that the presence and density of Freps are primarily related to the degree of lower motor neuron loss and show no correlation with any of the relatively extensive set of parameters for upper motor neuron dysfunction. SIGNIFICANCE: Freps are primarily related to lower motor neuron loss in ALS. PMID: 31760213 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - November 11, 2019 Category: Neurology Authors: Oguz Akarsu E, Sirin NG, Kocasoy Orhan E, Erbas B, Dede HO, Baslo MB, Idrisoglu HA, Oge AE Tags: Clin Neurophysiol Source Type: research

Corrigendum to 'SPiQE: An automated analytical tool for detecting and characterising fasciculations in amyotrophic lateral sclerosis' [Clin. Neurophysiol. 130 (2019) 1083-1090].
PMID: 31706721 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - November 6, 2019 Category: Neurology Authors: Bashford J, Wickham A, Iniesta R, Drakakis E, Boutelle M, Mills K, Shaw C Tags: Clin Neurophysiol Source Type: research

Which kinds of fasciculations are missed by ultrasonography in ALS?
PMID: 31703938 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - October 24, 2019 Category: Neurology Authors: Regensburger M Tags: Clin Neurophysiol Source Type: research

Connectivity measures suggest a sub-cortical generator of myoclonus in Angelman syndrome.
CONCLUSIONS: These neurophysiological findings suggest a subcortical generator of myoclonus in AS. SIGNIFICANCE: Myoclonus in AS has not a cortical origin as previously hypothesised. PMID: 31704627 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - October 24, 2019 Category: Neurology Authors: Ferlazzo E, Franceschetti S, Gasparini S, Elia M, Canafoglia L, Pantaleoni C, Ascoli M, D'Agostino T, Sueri C, Ferrigno G, Panzica F, Cianci V, Aguglia U Tags: Clin Neurophysiol Source Type: research

Muscle ultrasound in the assessment of oxaliplatin-induced neurotoxicity.
PMID: 31706720 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - October 24, 2019 Category: Neurology Authors: Pelosi L, Han CH, McKeage MJ Tags: Clin Neurophysiol Source Type: research

Sleep modulates effective connectivity: A study using intracranial stimulation and recording.
CONCLUSIONS: Sleep modulates brain excitability and reconfigures functional brain networks, depending on tissue epileptogenicity. SIGNIFICANCE: We found specific patterns of information flow during sleep in physiologic and pathologic structures, with possible implications for cognition. PMID: 31708382 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - October 24, 2019 Category: Neurology Authors: Arbune AA, Popa I, Mindruta I, Beniczky S, Donos C, Daneasa A, Mălîia MD, Băjenaru OA, Ciurea J, Barborica A Tags: Clin Neurophysiol Source Type: research

Muscle velocity recovery cycles: An evolving technique for assessing muscle fiber membrane properties.
PMID: 31694794 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - October 24, 2019 Category: Neurology Authors: Tankisi H Tags: Clin Neurophysiol Source Type: research

Poor working memory performance in healthy elderly adults with electroencephalographic risk of cognitive decline affects syntactic processing.
CONCLUSION: The findings suggest that the Risk group shows difficulties integrating information associated with the previous sentence context. SIGNIFICANCE: The electroencephalographic risk factor of cognitive decline might be not only a predictor of but also an indicator of current decline. PMID: 31698266 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - October 15, 2019 Category: Neurology Authors: Alatorre-Cruz GC, Silva-Pereyra J, Fernández T, Rodríguez-Camacho MA Tags: Clin Neurophysiol Source Type: research

TEMPORARY REMOVAL: Event-related potentials following contraction of respiratory muscles in pre-term and full-term infants.
Abstract The publisher regrets that this article has been temporarily removed. A replacement will appear as soon as possible in which the reason for the removal of the article will be specified, or the article will be reinstated. The full Elsevier Policy on Article Withdrawal can be found at https://www.elsevier.com/about/our-business/policies/article-withdrawal. PMID: 31677560 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - October 15, 2019 Category: Neurology Authors: Whitehead K, Jones L, Laudiano-Dray MP, Meek J, Fabrizi L Tags: Clin Neurophysiol Source Type: research

The network integration of epileptic activity in relation to surgical outcome.
Abstract OBJECTIVE: Epilepsy is a network disease with epileptic activity and cognitive impairment involving large-scale brain networks. A complex network is involved in the seizure and in the interictal epileptiform discharges (IEDs). Directed connectivity analysis, describing the information transfer between brain regions, and graph analysis are applied to high-density EEG to characterise networks. METHODS: We analysed 19 patients with focal epilepsy who had high-density EEG containing IED and underwent surgery. We estimated cortical activity during IED using electric source analysis in 72 atlas-based corti...
Source: Clinical Neurophysiology - October 14, 2019 Category: Neurology Authors: Carboni M, Rubega M, Iannotti GR, De Stefano P, Toscano G, Tourbier S, Pittau F, Hagmann P, Momjian S, Schaller K, Seeck M, Michel CM, van Mierlo P, Vulliemoz S Tags: Clin Neurophysiol Source Type: research

Reply to "MUNIX value dependence on surface electromyogram properties".
Reply to "MUNIX value dependence on surface electromyogram properties". Clin Neurophysiol. 2019 Oct 11;: Authors: Bostock H, Jacobsen AB, Tankisi H PMID: 31668553 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - October 11, 2019 Category: Neurology Authors: Bostock H, Jacobsen AB, Tankisi H Tags: Clin Neurophysiol Source Type: research

MUNIX value dependence on surface electromyogram properties.
PMID: 31668751 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - October 11, 2019 Category: Neurology Authors: Miralles F Tags: Clin Neurophysiol Source Type: research

Differentiating early Parkinson's disease and multiple system atrophy with parkinsonism by saccade velocity profiles.
CONCLUSION: Saccade profiles provide useful information for differentiating between PD and MSAP at early stages. While the changes in velocity profiles may be explained by the cerebellar and brainstem pathology in MSAP, the changes in velocity profile in both PD and MSAP correlated significantly with increasing severity of Parkinsonism in both disorders, suggesting a link with striatonigral pathology. SIGNIFICANCE: The differential changes in saccade velocity profiles of MSAP and PD may be used as a measure indexing the progression of cerebellar and basal ganglia dysfunction as well as for assessing the functional imp...
Source: Clinical Neurophysiology - September 23, 2019 Category: Neurology Authors: Terao Y, Tokushige SI, Inomata-Terada S, Fukuda H, Yugeta A, Ugawa Y Tags: Clin Neurophysiol Source Type: research

Epileptic activity in neurological deterioration after ischemic stroke, a continuous EEG study.
Abstract OBJECTIVE: Despite improvement in acute stroke care, almost 40% of patients with ischemic stroke present neurological deterioration. Neurological deterioration is associated with higher death and dependency rates. Neurological deterioration mechanisms are unknown, and half of neurological deterioration remains unexplained. We postulate that a substantial proportion of neurological deterioration in ischemic stroke is associated with periodic discharges/non-convulsive seizures that negatively impact the recovery of ischemic stroke and worsen symptoms. METHODS: Retrospective review of 24 h continuous EE...
Source: Clinical Neurophysiology - September 21, 2019 Category: Neurology Authors: Scoppettuolo P, Gaspard N, Depondt C, Legros B, Ligot N, Naeije G Tags: Clin Neurophysiol Source Type: research

Saccular function is associated with both angular and distance errors on the triangle completion test.
Abstract OBJECTIVE: The present study was designed to determine whether healthy older adults with age-related vestibular loss have deficits in spatial navigation. METHODS: 154 adults participating in the Baltimore Longitudinal Study of Aging were tested for semicircular canal, saccular, and utricular function and spatial navigation ability using the blindfolded Triangle Completion Test (TCT). Multiple linear regression was used to investigate the relationships between each measure of vestibular function and performance on the TCT (angular error, end point error, and distance walked) while controlling for age ...
Source: Clinical Neurophysiology - September 17, 2019 Category: Neurology Authors: Anson ER, Ehrenburg MR, Wei EX, Bakar D, Simonsick E, Agrawal Y Tags: Clin Neurophysiol Source Type: research

Prospective observational study: Fast ripple localization delineates the epileptogenic zone.
Abstract OBJECTIVE: To investigate spatial correlation between interictal HFOs and neuroimaging abnormalities, and to determine if complete removal of prospectively identified interictal HFOs correlates with post-surgical seizure-freedom. METHODS: Interictal fast ripples (FRs: 250-500 Hz) in 19 consecutive children with pharmacoresistant focal epilepsy who underwent extra-operative electrocorticography (ECoG) recording were prospectively analyzed. The interictal FRs were sampled at 2000 Hz and were visually identified during 10 min of slow wave sleep. Interictal FRs, MRI and FDG-PET were delineated on pat...
Source: Clinical Neurophysiology - September 17, 2019 Category: Neurology Authors: Nariai H, Hussain SA, Bernardo D, Fallah A, Murata KK, Nguyen JC, Rajaraman RR, Rao LM, Matsumoto JH, Lerner JT, Salamon N, Elashoff D, Sankar R, Wu JY Tags: Clin Neurophysiol Source Type: research

What are you looking at? Unrippling terminology for high frequency activity.
PMID: 31563811 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - September 17, 2019 Category: Neurology Authors: Noorlag L, van Klink N, Huiskamp G, Zijlmans M Tags: Clin Neurophysiol Source Type: research

Photosensitive epilepsy and long QT: expanding Timothy syndrome phenotype.
PMID: 31563812 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - September 17, 2019 Category: Neurology Authors: Po' C, Zordan R, Vecchi M, Cerutti A, Sartori S, Trevisson E, Ludwig K, Castaldi B, Salviati L, Leoni L, Toldo I Tags: Clin Neurophysiol Source Type: research

Implicit learning in the developing brain: An exploration of ERP indices for developmental disorders.
PMID: 31542253 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - September 10, 2019 Category: Neurology Authors: Daikoku T Tags: Clin Neurophysiol Source Type: research

International Federation of Clinical Neurophysiology (IFCN) - EEG research workgroup: Recommendations on frequency and topographic analysis of resting state EEG rhythms. Part 1: Applications in clinical research studies.
Abstract In 1999, the International Federation of Clinical Neurophysiology (IFCN) published "IFCN Guidelines for topographic and frequency analysis of EEGs and EPs" (Nuwer et al., 1999). Here a Workgroup of IFCN experts presents unanimous recommendations on the following procedures relevant for the topographic and frequency analysis of resting state EEGs (rsEEGs) in clinical research defined as neurophysiological experimental studies carried out in neurological and psychiatric patients: (1) recording of rsEEGs (environmental conditions and instructions to participants; montage of the EEG electrodes; reco...
Source: Clinical Neurophysiology - September 6, 2019 Category: Neurology Authors: Babiloni C, Barry RJ, Başar E, Blinowska KJ, Cichocki A, Drinkenburg WHIM, Klimesch W, Knight RT, Lopes da Silva F, Nunez P, Oostenveld R, Jeong J, Pascual-Marqui R, Valdes-Sosa P, Hallett M Tags: Clin Neurophysiol Source Type: research

Relationship between EMG-detected and ultrasound-detected fasciculations in amyotrophic lateral sclerosis: A prospective cohort study.
Abstract OBJECTIVES: Fasciculation potentials (FP) are an important consideration in the electrophysiological diagnosis of ALS. Muscle ultrasonography (MUS) has a higher sensitivity in detecting fasciculations than electromyography (EMG), while in some cases, it is unable to detect EMG-detected fasciculations. We aimed to investigate the differences of FP between the muscles with and without MUS-detected fasciculations (MUS-fas). METHODS: Thirty-one consecutive patients with sporadic ALS were prospectively recruited and in those, both needle EMG and MUS were performed. Analyses of the amplitude, duration, and...
Source: Clinical Neurophysiology - August 28, 2019 Category: Neurology Authors: Bokuda K, Shimizu T, Kimura H, Morishima R, Kamiyama T, Kawata A, Nakayama Y, Isozaki E Tags: Clin Neurophysiol Source Type: research

Corrigendum to 'A pilot study on the efficacy of transcranial direct current stimulation applied to the pharyngeal motor cortex for dysphagia associated with brainstem involvement in multiple sclerosis' [Clin. Neurophysiol. 130 (2019) 1017-1024].
PMID: 31473144 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - August 28, 2019 Category: Neurology Authors: Restivo DA, Alfonsi E, Casabona A, Hamdy S, Tassorelli C, Panebianco M, Marchese-Ragona R, Quartarone A, Centonze D, Pavone A, Bassi MS Tags: Clin Neurophysiol Source Type: research

F Wave Analyzer, a system for repeater F-waves detection: Application in patients with amyotrophic lateral sclerosis.
CONCLUSION: In ALS, the high numbers of Freps, reduced overall F-wave persistence and increased F-wave amplitude measurements in a relatively unaffected nerve-muscle complex reflects excitability alterations of the corresponding motor neuron pool. Overall, automatic analysis facilitates accurate and fast detection of Freps and could be useful in other clinical settings. SIGNIFICANCE: Analysis of repeater F-waves is expected to provide new insight regarding ALS pathophysiology and utilized for monitoring in clinical drug trials. PMID: 31472478 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - August 16, 2019 Category: Neurology Authors: Veltsista D, Papapavlou C, Chroni E Tags: Clin Neurophysiol Source Type: research

Diagnostic added value of electrical source imaging in presurgical evaluation of patients with epilepsy: A prospective study.
CONCLUSIONS: ESI provides non-redundant information in one third of the patients undergoing presurgical evaluation. SIGNIFICANCE: This study provides evidence for the diagnostic added value of ESI in presurgical evaluation. PMID: 31466846 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - August 16, 2019 Category: Neurology Authors: Foged MT, Martens T, Pinborg LH, Hamrouni N, Litman M, Rubboli G, Leffers AM, Ryvlin P, Jespersen B, Paulson OB, Fabricius M, Beniczky S Tags: Clin Neurophysiol Source Type: research

Auditory gating in adults with dyslexia: An ERP account of diminished rapid neural adaptation.
CONCLUSIONS: Neural adaptation occurs by approximately 100 ms after stimulus presentation and is diminished in adults with dyslexia. This complements fMRI findings of relevant brain regions by implying a time window representing sensory and pre-attentive auditory processes. SIGNIFICANCE: The association between gating magnitude and word discrimination contributes to a neurophysiological account of underspecified word representations. PMID: 31451333 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - August 12, 2019 Category: Neurology Authors: Peter B, McCollum H, Daliri A, Panagiotides H Tags: Clin Neurophysiol Source Type: research

Lack of evidence for interhemispheric inhibition in the lower face primary motor cortex.
CONCLUSION: In the DAO there was no evidence of IHI even though this was clear in hand and axial muscles. Control experiments excluded a transcallosal origin of the facilitation observed at the shortest intervals. SIGNIFICANCE: Data suggest that integrated bilateral control of facial muscles occurs mainly at the level of brainstem circuits engaged by corticobulbar output from fM1. PMID: 31437744 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - August 8, 2019 Category: Neurology Authors: Ginatempo F, Manzo N, Rothwell JC, Deriu F Tags: Clin Neurophysiol Source Type: research

A new potential specifically marks the sensory thalamus in anaesthetised patients.
CONCLUSIONS: VHFOs are widely extending and cannot be ascribed to the V.c. HFOs in patients under general anaesthesia can serve as a landmark to identify the V.c. in thalamic DBS surgery. SIGNIFICANCE: Thalamic processing involves nuclei other than the V.c, and HFO can be used to improve DBS surgery. PMID: 31437745 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - August 8, 2019 Category: Neurology Authors: Pastor J, Vega-Zelaya L Tags: Clin Neurophysiol Source Type: research

Motor unit number index (MUNIX) and compound muscle action potential amplitude: A reappraisal.
g EV PMID: 31416706 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - July 31, 2019 Category: Neurology Authors: Nandedkar SD, Barkhaus PE, Stålberg EV Tags: Clin Neurophysiol Source Type: research

Reply to "Motor Unit Number Index (MUNIX) and Compound Muscle Action Potential".
Reply to "Motor Unit Number Index (MUNIX) and Compound Muscle Action Potential". Clin Neurophysiol. 2019 Jul 31;: Authors: Bostock H, Jacobsen AB, Tankisi H PMID: 31409557 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - July 31, 2019 Category: Neurology Authors: Bostock H, Jacobsen AB, Tankisi H Tags: Clin Neurophysiol Source Type: research

Oscillatory connectivity as a diagnostic marker of dementia due to Alzheimer's disease.
CONCLUSIONS: The diagnostic accuracies for EEG connectivity measures are higher than findings from studies investigating EEG power and conventional Alzheimer's disease biomarkers. Furthermore, decreased alpha coherence is one of the earliest changes in Alzheimer's disease and associated with memory function. SIGNIFICANCE: EEG connectivity measures may be useful supplementary diagnostic classifiers. PMID: 31408790 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - July 29, 2019 Category: Neurology Authors: Musaeus CS, Engedal K, Høgh P, Jelic V, Mørup M, Naik M, Oeksengaard AR, Snaedal J, Wahlund LO, Waldemar G, Andersen BB Tags: Clin Neurophysiol Source Type: research

Can theta burst stimulation safely influence auditory hearing thresholds in healthy young adults?
CONCLUSIONS: A single stimulation session led to an effective neuromodulation of the auditory cortex, reflected in lower thresholds when using iTBS. SIGNIFICANCE: These encouraging results with this safe noninvasive tool suggest that iTBS may have the potential to positively influence hearing thresholds. PMID: 31408791 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - July 29, 2019 Category: Neurology Authors: Pinto N, Oliveira I, Ferreira J, Gama J, Vaz Pato M Tags: Clin Neurophysiol Source Type: research

Stability of a chronic implanted brain-computer interface in late-stage amyotrophic lateral sclerosis.
CONCLUSIONS: The implanted brain-computer interface proves to be robust in an individual with late-stage ALS, given stable performance and control signal for over 36 months. SIGNIFICANCE: These findings are relevant for the future of implantable brain-computer interfaces along with other brain-sensing technologies, such as responsive neurostimulation. PMID: 31401488 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - July 27, 2019 Category: Neurology Authors: Pels EGM, Aarnoutse EJ, Leinders S, Freudenburg ZV, Branco MP, van der Vijgh BH, Snijders TJ, Denison T, Vansteensel MJ, Ramsey NF Tags: Clin Neurophysiol Source Type: research

Frequency and characteristic features of REM sleep without atonia.
CONCLUSIONS: RSWA is a frequent finding in the context of antidepressant use or synucleinopathies. iRSWA subjects reported increased excessive daytime sleepiness and more often had excessive daytime sleepiness as polysomnography indication. SIGNIFICANCE: Our study provides evidence for high frequency of RSWA, underscoring the need for longitudinal studies in iRSWA patients, with interest for conversion to synucleinopathies. PMID: 31401491 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - July 27, 2019 Category: Neurology Authors: Dijkstra F, Viaene M, Crosiers D, De Volder I, Cras P Tags: Clin Neurophysiol Source Type: research

EEG reactivity predicts recovery of consciousness in patients with acute brain injury and signs of intracranial hypertension.
PMID: 31400576 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - July 26, 2019 Category: Neurology Authors: Longhi L, Cavalleri G, Ferri F, Lorini L, Zangari R, Rottoli MR, Frigeni B Tags: Clin Neurophysiol Source Type: research