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Condition: Obesity

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Total 4516 results found since Jan 2013.

Clinical features in liver cirrhosis patients who have experienced ischemic stroke.
CONCLUSION: Our results show that a comparatively high frequency of ischemic stroke occurs in patients with alcohol-induced liver cirrhosis and in patients with a less compromised liver function. In addition, it was found that most patients possessed at least one risk factor of ischemic stroke. PMID: 25599784 [PubMed - in process]
Source: The Turkish Journal of Gastroenterology - December 1, 2014 Category: Gastroenterology Authors: Kim KM, Hwang JW, Shim SG Tags: Turk J Gastroenterol Source Type: research

A dose‐response meta‐analysis of the impact of body mass index on stroke and all‐cause mortality in stroke patients: a paradox within a paradox
Summary The obesity paradox is often attributed to fat acting as a buffer to protect individuals in fragile metabolic states. If this was the case, one would predict that the reverse epidemiology would be apparent across all causes of mortality including that of the particular disease state. We performed a dose‐response meta‐analysis to assess the impact of body mass index (BMI) on all‐cause and stroke‐specific mortality among stroke patients. Data from relevant studies were identified by systematically searching PubMed, OVID and Scopus databases and were analysed using a random‐effects dose‐response model. Eig...
Source: Obesity Reviews - March 1, 2015 Category: Eating Disorders and Weight Management Authors: M. Bagheri, J. R. Speakman, S. Shabbidar, F. Kazemi, K. Djafarian Tags: Review Source Type: research

The interactive effect of diabetes and central obesity on stroke: a prospective cohort study of inner Mongolians
Conclusions: The participants who were both diabetic and centrally obese had significantly higher risk for incident stroke than the combination of individuals who individually had either condition among Mongolian population. This study suggests that central obesity and diabetes act synergistically to increase the risk of stroke.
Source: BMC Neurology - April 28, 2015 Category: Neurology Authors: Jennifer OlofindayoHao PengYan LiuHongmei LiMingzhi ZhangAili WangYonghong Zhang Source Type: research

The Nutraceutical Potential of Omega-3 Alpha-Linolenic Acid in Reducing the Consequences of Stroke.
Abstract Stroke is a worldwide major cause of mortality and morbidity. Preclinical studies have identified over 1000 molecules with brain-protective properties. More than 200 clinical trials have evaluated neuroprotective candidates for ischemic stroke yet, to date almost all failed, leading to a re-analysis of treatment strategies against stroke. An emerging view is to seek combinatory therapy, or discovering molecules able to stimulate multiple protective and regenerative mechanisms. A pertinent experimental approach to identify such candidates is the study of brain preconditioning, which refers to how the brain...
Source: Biochimie - June 16, 2015 Category: Biochemistry Authors: Blondeau N Tags: Biochimie Source Type: research

Association of Gallbladder Polyp and Stroke: A Nationwide, Population-Based Study
Abstract: Gallbladder polyp (GP) and stroke share several metabolic disorders as risk factors. We assessed the association between GP and subsequent stroke risk. From 2000 to 2011, patients with GP aged>20 years were identified from the Longitudinal Health Insurance Database 2000. Of the 15,975 examined patients, 12,780 and 3195 were categorized into the non-GP and GP cohorts, respectively. The relative risks of stroke were estimated using the Cox proportional hazard model after adjusting for age, sex, and comorbidities. The overall incidence of stroke was higher in the GP cohort than in the non-GP cohort (6.66 vs 5.20/100...
Source: Medicine - December 1, 2015 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research

The prevalence and risk factors of stroke in patients with chronic schizophrenia
Conclusion: The prevalence of stroke is relatively higher in Chinese patients with chronic schizophrenia. Chronic schizophrenia patients are more likely to suffer from stroke; meanwhile, a number of risk factors were identified, including old age, female sex, smoking history, combined medication with a variety of drugs, high doses, obesity, and high blood pressure. Keywords: schizophrenia, stroke, risk, risk factors
Source: Neuropsychiatric Disease and Treatment - May 9, 2016 Category: Psychiatry Tags: Neuropsychiatric Disease and Treatment Source Type: research

Sex ‐related differences in abdominal obesity impact on ischemic stroke risk
ConclusionsIncreased BMI was related to a lower risk of stroke in men. Abdominal obesity was associated with ischemic stroke in women. The impact of abdominal obesity on stroke risk differs by sex.
Source: European Journal of Neurology - December 29, 2016 Category: Neurology Authors: A. Rodr íguez‐Campello, J. Jiménez‐Conde, Á. Ois, E. Cuadrado‐Godia, E. Giralt‐Steinhauer, R. M. Vivanco, C. Soriano‐Tárraga, I. Subirana, D. Muñoz, A. Gómez‐González, A. Puig‐Pijoan, J. Roquer Tags: Original Article Source Type: research

Prevalence and covariates of uncontrolled hypertension in ischemic stroke survivors: the Norwegian stroke in the young study.
CONCLUSION: Uncontrolled hypertension was highly prevalent in ischemic stroke survivors <60 years and associated with co-presence of obesity and functional and structural arterial damage. Our results highlight the unmet potential and challenge of optimization of hypertension diagnosis and management in order to prevent recurrent vascular events in ischemic stroke survivors. PMID: 29334265 [PubMed - as supplied by publisher]
Source: Blood Pressure - January 16, 2018 Category: Hematology Tags: Blood Press Source Type: research

Cluster Enrollment: A Screening Tool for Stroke Risk Factors in Minority Women Caregivers.
CONCLUSIONS: Using cluster enrollment, we discovered minority female caregivers were more likely to have unknown or poorly controlled vascular risk factors compared to stroke patients. Innovative health screening tools may benefit the extended family of minority patients participating in clinical trials. PMID: 30442422 [PubMed - as supplied by publisher]
Source: Journal of the National Medical Association - November 19, 2018 Category: General Medicine Tags: J Natl Med Assoc Source Type: research

Body Mass Index and Prognosis in Ischemic Stroke Patients With Type 2 Diabetes Mellitus
This study showed the overall presence of the obesity paradox in stroke patients with T2DM. However, obese patients had different risks of cardiovascular events and stroke.
Source: Frontiers in Neurology - June 4, 2019 Category: Neurology Source Type: research

Impact of aging and comorbidities on ischemic stroke outcomes in preclinical animal models: A translational perspective.
Abstract Ischemic stroke is a highly complex and devastating neurological disease. The sudden loss of blood flow to a brain region due to an ischemic insult leads to severe damage to that area resulting in the formation of an infarcted tissue, also known as the ischemic core. This is surrounded by the peri-infarct region or penumbra that denotes the functionally impaired but potentially salvageable tissue. Thus, the penumbral tissue is the main target for the development of neuroprotective strategies to minimize the extent of ischemic brain damage by timely therapeutic intervention. Given the limitations of reperf...
Source: Experimental Neurology - October 6, 2020 Category: Neurology Authors: Candelario-Jalil E, Paul S Tags: Exp Neurol Source Type: research

Association of LDLc to HDLc ratio with carotid plaques in a community-based population with a high stroke risk: a cross-sectional study in China.
CONCLUSION: Higher LDLc/HDLc was significantly associated with the presence of carotid plaques in the Chinese population with a high risk of stroke. PMID: 33242435 [PubMed - as supplied by publisher]
Source: Clinical Biochemistry - November 23, 2020 Category: Biochemistry Authors: Geng Y, Liu Y, Chen Y, Zhang Z, Wang L, Li X, Xia B, Song B, Zhang H Tags: Clin Biochem Source Type: research

An Analysis of the Potential Relationship of Triglyceride Glucose and Body Mass Index With Stroke Prognosis
Conclusion: Overweight/obese patients with ischemic stroke have better survival than patients with low/normal weight. The association of BMI and stroke outcome is not changed by TYG index.
Source: Frontiers in Neurology - April 22, 2021 Category: Neurology Source Type: research

Risk factors predisposing to acute stroke in India: a prospective study
Conclusion: The foremost risk factors for stroke in India, hypertension and diabetes, need to be controlled and treated like other global high-risk populations for stroke prevention. The NIHSS scores highlight the relationship between risk factors and stroke severity.
Source: Journal of Hypertension - October 15, 2021 Category: Cardiology Tags: ORIGINAL PAPERS: Risk factors Source Type: research

The Effects of Body Mass Index on In-hospital mortality following first ischemic or hemorrhagic stroke events: Does the "obesity paradox" apply?
CONCLUSION: Obese patients are less likely to die during hospitalization following first-time non-subarachnoid hemorrhage and ischemic stroke than non-overweight/non-obese patients. These findings support the "obesity paradox" concept, though more research is needed for recurrent stroke patients.PMID:34691415 | PMC:PMC8519764 | DOI:10.1016/j.amsu.2021.102839
Source: Annals of Medicine - October 25, 2021 Category: Internal Medicine Authors: Kevin J Kinter Robert Alfaro Christopher Kinter Lucas Suder Zachary Davis Pura Rodriguez Juan Gabriel Ruiz Juan Carlos Zevallos Adel Elkbuli Source Type: research