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Condition: Obesity

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Guidelines for the Prevention of Stroke in Women: A Statement for Healthcare Professionals From the American Heart Association/American Stroke Association AHA/ASA Guideline
Conclusions— To more accurately reflect the risk of stroke in women across the lifespan, as well as the clear gaps in current risk scores, we believe a female-specific stroke risk score is warranted.
Source: Stroke - April 28, 2014 Category: Neurology Authors: Bushnell, C., McCullough, L. D., Awad, I. A., Chireau, M. V., Fedder, W. N., Furie, K. L., Howard, V. J., Lichtman, J. H., Lisabeth, L. D., Pina, I. L., Reeves, M. J., Rexrode, K. M., Saposnik, G., Singh, V., Towfighi, A., Vaccarino, V., Walters, M. R., o Tags: AHA Statements and Guidelines AHA/ASA Guideline Source Type: research

Predictors of Noticing Stroke Educational Campaign
Conclusions: Tobacco smokers in particular should be targeted by stroke awareness campaigns, for example, through health warning labels on cigarette packs. People with some stroke risk factors, such as heart disease and obesity, are responsive to information about stroke. Therefore, educational campaigns should target the groups with increased risk of stroke.
Source: Journal of Stroke and Cerebrovascular Diseases - April 11, 2014 Category: Neurology Authors: Petra Sobotková, David Goldemund, Michal Reif, Robert Mikulík Tags: Original Articles Source Type: research

Neighborhood socioeconomic status and the prevalence of stroke and coronary heart disease in rural China: A population‐based study
ConclusionsThere were differences in vascular risk across rural villages in China, with higher lifetime stroke and CHD prevalence in higher‐income villages. For CHD, neighborhood effects were stronger among younger residents of high‐income villages. The results may have implications for public health interventions targeting populations at risk.
Source: International Journal of Stroke - August 4, 2014 Category: Neurology Authors: Xun Tang, Daniel T. Laskowitz, Liu He, Truls Østbye, Janet Prvu Bettger, Yang Cao, Na Li, Jingrong Li, Zongxin Zhang, Jianjiang Liu, Liping Yu, Haitao Xu, Yonghua Hu, Larry B. Goldstein Tags: Research Source Type: research

Predictors Of Early Mortality And Bad Outcome In Ischemic Stroke (P3.072)
Conclusion: identifying predictors of early mortality or post-stroke disability is mandatory in order to recognize opportunities of improvement and develop strategies for clinical care in this specific subgroup of patients. A multidisciplinary approach is essential to reduce clinical complications and to improve follow up after the hospitalization period.Disclosure: Dr. Luzzi has nothing to disclose. Dr. Zurru has nothing to disclose. Dr. Alonzo has nothing to disclose. Dr. Brescacin has nothing to disclose. Dr. Pigretti has nothing to disclose. Dr. Camera has nothing to disclose. Dr. Colla Machado has nothing to disclose....
Source: Neurology - April 8, 2015 Category: Neurology Authors: Luzzi, A., Zurru, M., Alonzo, C., Brescacin, L., Pigretti, S., Camera, L., Colla Machado, P., Waisman, G., Cristiano, E. Tags: Cerebrovascular Disease and Interventional Neurology: Ischemic Stroke Outcome Source Type: research

Stroke Induces Prolonged Changes in Lipid Metabolism, the Liver and Body Composition in Mice
AbstractDuring recovery, stroke patients are at risk of developing long-term complications that impact quality of life, including changes in body weight and composition, depression and anxiety, as well as an increased risk of subsequent vascular events. The aetiologies and time-course of these post-stroke complications have not been extensively studied and are poorly understood. Therefore, we assessed long-term changes in body composition, metabolic markers and behaviour after middle cerebral artery occlusion in mice. These outcomes were also studied in the context of obesity, a common stroke co-morbidity proposed to prote...
Source: Translational Stroke Research - December 20, 2019 Category: Neurology Source Type: research

Obesity Drives Delayed Infarct Expansion, Inflammation, and Distinct Gene Networks in a Mouse Stroke Model
AbstractObesity is associated with chronic peripheral inflammation, is a risk factor for stroke, and causes increased infarct sizes. To characterize how obesity increases infarct size, we fed a high-fat diet to wild-type C57BL/6J mice for either 6  weeks or 15 weeks and then induced distal middle cerebral artery strokes. We found that infarct expansion happened late after stroke. There were no differences in cortical neuroinflammation (astrogliosis, microgliosis, or pro-inflammatory cytokines) either prior to or 10 h after stroke, and also no differences in stroke size at 10 h. However, by 3 days after stroke, animals...
Source: Translational Stroke Research - June 24, 2020 Category: Neurology Source Type: research

Distribution of risk factors differs from coronary heart disease and stroke in China: a national population survey
Conclusions The distribution of risk factors for CHD and stroke were substantial differences. More specific prevention and control measures should be formulated according to the distribution differences of risk factors related to CVD.
Source: BMJ Open - November 24, 2022 Category: General Medicine Authors: Li, Y., Yin, L., Shen, Y., Wang, A., Zhou, L., Gao, Y., Li, Y., Lu, J., Shi, S., Tian, C., Xu, Y., Wang, L., on behalf of the China National Stroke Screening Survey investigators Tags: Open access, Public health Source Type: research

Risk of ischemic stroke during periods of warfarin discontinuation for surgical procedures: A longitudinal study of 4060 patients with atrial fibrillation (P1.058)
CONCLUSIONS: The risk associated with discontinuation of warfarin for procedures must be recognized and considered in the risk benefit analysis of any procedure.Disclosure: Dr. Jahangir has nothing to disclose. Dr. Malik has nothing to disclose. Dr. Suri has nothing to disclose. Dr. Qureshi has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Jahangir, N., Malik, A., Suri, M., Qureshi, A. Tags: Cerebrovascular Disease and Interventional Neurology: Atrial Fibrillation and Cardio-embolic Stroke Source Type: research

Associations of Serum C-Peptide Level with Body Fat Distribution and Ever Stroke in Nondiabetic Subjects
Conclusion: The serum C-peptide level is strongly associated with the ever stroke in nondiabetic subjects and significantly associated with total and regional body fat distribution.
Source: Journal of Stroke and Cerebrovascular Diseases - October 17, 2013 Category: Neurology Authors: Ying Li, Lu Meng, Yue Li, Yasuto Sato Tags: Original Articles Source Type: research

Sex Differences in Trends of Incidence and Mortality of First-Ever Stroke in Rural Tianjin, China, From 1992 to 2012 Clinical Sciences
Conclusions— There was a significant increase in the incidence of first-ever stroke in women annually and a declining trend in the male/female rate ratio in rural China during the past 21 years. These results suggest that stroke will become one of the major diseases affecting women in future decades in China.
Source: Stroke - May 27, 2014 Category: Neurology Authors: Wang, J., Ning, X., Yang, L., Tu, J., Gu, H., Zhan, C., Zhang, W., Su, T.-C. Tags: Epidemiology Clinical Sciences Source Type: research

Disparities among Asians and Native Hawaiians and Pacific Islanders with ischemic stroke
Conclusions: Asians, NHPI, and whites with ischemic stroke have substantially different cardiovascular risk factors. Targeted secondary prevention will be important in reducing disparities among these racial groups.
Source: Neurology - February 25, 2013 Category: Neurology Authors: Nakagawa, K., Koenig, M. A., Asai, S. M., Chang, C. W., Seto, T. B. Tags: All Cerebrovascular disease/Stroke, Risk factors in epidemiology ARTICLE Source Type: research

Association of Body Mass Index and Mortality After Acute Ischemic Stroke Original Articles
Conclusions— Severe obesity is associated with increased poststroke mortality in middle-aged and older adults. Stroke patients with class 2 obesity had the lowest mortality risk. More research is needed to determine weight management goals among stroke survivors.
Source: Circulation: Cardiovascular Quality and Outcomes - January 21, 2014 Category: Cardiology Authors: Skolarus, L. E., Sanchez, B. N., Levine, D. A., Baek, J., Kerber, K. A., Morgenstern, L. B., Smith, M. A., Lisabeth, L. D. Tags: Obesity, Cerebrovascular disease/stroke Original Articles Source Type: research

Investigation of Vaspin Level in Patients with Acute Ischemic Stroke
This study was intended to investigate the relation between vaspin and stroke and stroke and other risk factors.Methods: A total of 50 patients with stroke, as 28 men (56%) and 22 women (44%), and a total of 50 healthy individuals, as 25 men (50%) and 25 women (50%), were enrolled in the study. Blood samples were taken in the acute period (first 48 hours) in the patient group, and serum vaspin levels were measured. Vaspin level was also measured in the control group. The association of vaspin with the lipid parameters, gender, and the severity of internal carotid artery (ICA) stenosis in the patient group was evaluated. S...
Source: Journal of Stroke and Cerebrovascular Diseases - April 16, 2013 Category: Neurology Authors: Hasan S. Cura, Hasan H. Özdemir, Caner F. Demir, Serpil Bulut, Nevin İlhan, Mehmet Fatih Inci Tags: Original Articles Source Type: research

Obesity Paradox in Ischemic Stroke: Clinical and Molecular Insights
AbstractIt has recently emerged the concept of “obesity paradox,” a term used to describe the unexpected improved prognosis and lower mortality rates found in several diseases in patients with higher body weight. Concerning stroke, few clinical studies have assessed this obesity paradox showing contradictory results. Therefore, our aim was t o compare clinical evolution and inflammatory balance of obese and non-obese patients after ischemic stroke. We designed a prospective case-control study in patients with acute ischemic stroke categorized into obese (body mass index, BMI ≥ 30 kg/m2) and non-obese (BMI  <...
Source: Translational Stroke Research - April 12, 2019 Category: Neurology Source Type: research

Diabetes and obesity are associated with disability in community-dwelling stroke survivors: A cross-sectional study of 37,955 Behavioral Risk Factor Surveillance System respondents
Conclusion. Stroke survivors with obesity or diabetes experience increased risk for disability compared to survivors without these chronic conditions. Interventions for managing disability, obesity, and diabetes concomitantly may be warranted and deserve further consideration.PMID:33775239 | DOI:10.1080/10749357.2021.1904537
Source: Topics in Stroke Rehabilitation - March 29, 2021 Category: Neurology Authors: Ryan R Bailey Molly Conroy Source Type: research