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IJERPH, Vol. 19, Pages 4807: Stroke Risk Factors of Stroke Patients in China: A Nationwide Community-Based Cross-Sectional Study
Conclusions: The most common risk factors for community stroke patients in China are hypertension, dyslipidemia, and overweight or obesity. The stroke community patients’ suboptimal awareness and treatment of hypertension, and suboptimal awareness, treatment, and control of diabetes, and dyslipidemia are significant problems in China.
Source: International Journal of Environmental Research and Public Health - April 15, 2022 Category: Environmental Health Authors: Jingyi Chen Qianrang Zhu Lianlong Yu Yuqian Li Shanshan Jia Jian Zhang Tags: Article Source Type: research

China stroke surveillance report 2021
AbstractSince 2015, stroke has become the leading cause of death and disability in China, posing a significant threat to the health of its citizens as a major chronic non-communicable disease. According to the China Stroke High-risk Population Screening and Intervention Program, an estimated 17.8 million [95% confidence interval (CI) 17.6 –18.0 million] adults in China had experienced a stroke in 2020, with 3.4 million (95% CI 3.3–3.5 million) experiencing their first-ever stroke and another 2.3 million (95% CI 2.2–2.4 million) dying as a result. Additionally, approximately 12.5% (95% CI 12.4–12.5%) of stroke survi...
Source: Military Medical Research - July 19, 2023 Category: International Medicine & Public Health Source Type: research

Assessment of Stroke Risk Factors in Southern Arizona (P02.054)
CONCLUSIONS: Despite a higher incidence of stroke, Hispanic concern regarding stroke risk factors is much lower than non-Hispanics. This suggests that knowledge linking risk factors for stroke and incident stroke may be lacking in Hispanic communities. Lessened concern regarding stroke risk factors may contribute to an increase incidence in stroke and to a worse outcome in this population. Hispanics increased interest in health promotion programs may afford one approach to addressing this problem. This data suggest that despite historically worse stroke outcomes, preventative efforts may be beneficial in raising stroke ris...
Source: Neurology - February 14, 2013 Category: Neurology Authors: Nokes, B., Sim, Y., Byreddy, S., Chong, J., Drake, K., Labiner, D., Coull, B. Tags: P02 Cerebrovascular Disease II Source Type: research

Prolyl Carboxypeptidase Activity Decline Correlates with Severity and Short-Term Outcome in Acute Ischemic Stroke.
Abstract Prolyl carboxypeptidase (PRCP) is an enzyme associated with cerebrovascular risk factors such as hypertension, diabetes mellitus, obesity and hyperlipidemia. We aim to evaluate the relation between serum PRCP activity and severity, evolution and outcome of acute ischemic stroke. We used a specific RP-HPLC activity assay to measure PRCP activity in serum of 50 stroke patients at admission, and at 24 h, 72 h and 7 days after stroke onset to assess correlations with stroke severity based on the National Institutes of Health Stroke scale score (NIHSS), infarct volume on brain MRI scan, stroke outcome based...
Source: Neurochemical Research - November 5, 2014 Category: Neuroscience Authors: Kehoe K, Brouns R, Verkerk R, Engelborghs S, De Deyn PP, Hendriks D, De Meester I Tags: Neurochem Res Source Type: research

Age and the metabolic syndrome as risk factors for ischemic stroke: improving preclinical models of ischemic stroke.
Authors: Lucke-Wold BP, Turner RC, Lucke-Wold AN, Rosen CL, Huber JD Abstract Ischemic stroke represents a leading cause of morbidity and mortality in the developed world. This disabling and sometimes fatal event puts an ever increasing burden on the family members and medical professionals who care for stroke victims. Preclinical ischemic stroke research has predominantly utilized young adult, healthy animals, a clear discrepancy when considering the clinical population affected by stroke. A broad spectrum of risk factors such as age, obesity, diabetes, and hypertension has been associated with an increased stroke...
Source: The Yale Journal of Biology and Medicine - November 26, 2014 Category: Universities & Medical Training Tags: Yale J Biol Med Source Type: research

Body Mass Index and Stroke Subtype in a Young Adult Stroke Population (I12-5D)
CONCLUSIONS: In our group of young adult stroke patients, we found the highest BMI in the group with intracranial atherosclerosis. Although this group represented a small number of patients, this young adult population is at increased risk for future strokes. It is important to educate them on lifestyle modifications such as weight loss and exercise in addition to the treatment of hypertension, diabetes mellitus and hyperlipidemia.Disclosure: Dr. Youn has nothing to disclose. Dr. Aung has nothing to disclose. Dr. Afrasiabi has nothing to disclose. Dr. Clark has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Youn, J., Aung, T., Afrasiabi, M., Clark, J. Tags: Obesity and Neurological Disorders Poster Presentations Source Type: research

Obstructive Sleep Apnea as an Independent Stroke Risk Factor: A Review of the Evidence, Stroke Prevention Guidelines, and Implications for Neuroscience Nursing Practice
Discussion: OSA is highly prevalent in patients with stroke/TIA independently increasing stroke risk. CPAP studies revealed reduced stroke recurrence and improved recovery with feasible initiation in stroke units. Patients with stroke/TIA have less OSA-associated daytime sleepiness and obesity, making the usual screening tools insufficient and CPAP adherence challenging. Treating OSA decreases stroke prevalence and mortality. OSA initiatives empower neuroscience nurses to integrate this OSA evidence into clinical practice and improve stroke/TIA patient outcomes.
Source: Journal of Neuroscience Nursing - May 3, 2016 Category: Neuroscience Tags: Article Source Type: research

Sex differences in neuroinflammation and neuroprotection in ischemic stroke.
Abstract Stroke is not only a leading cause of mortality and morbidity worldwide it also disproportionally affects women. There are currently over 500,000 more women stroke survivors in the US than men, and elderly women bear the brunt of stroke-related disability. Stroke has dropped to the fifth leading cause of death in men, but remains the third in women. This review discusses sex differences in common stroke risk factors, the efficacy of stroke prevention therapies, acute treatment responses, and post-stroke recovery in clinical populations. Women have an increased lifetime risk of stroke compared to men, larg...
Source: Cell Research - November 23, 2016 Category: Cytology Authors: Spychala MS, Honarpisheh P, McCullough LD Tags: J Neurosci Res Source Type: research

Prevalence and risk factors of stroke in the elderly in Northern China: data from the National Stroke Screening Survey
AbstractBackgroundThe overall global burden of stroke is considerable and increasing. In China, stroke is the leading cause of death and disability.MethodsFor this study, we used data from the National Stroke Screening Survey in 2012 and the 2010 Chinese population from sixth National Census of Populations to calculate a standardized (by age, gender, and education) stroke prevalence. Prevalence, risk factors, and management of stroke were compared by gender, age, and site.FindingsThe standardized prevalence rate of survival stroke patients in study population aged 60 and older was 4.94% in total. Hypertension was the most ...
Source: Journal of Neurology - April 14, 2019 Category: Neurology Source Type: research

Filling the gaps on stroke research: focus on inflammation and immunity.
Abstract For the last two decades, researchers have placed hopes in a new era in which a combination of reperfusion and neuroprotection would revolutionize the treatment of stroke. Nevertheless, despite the thousands of papers available in the literature showing positive results in preclinical stroke models, randomized clinical trials have failed to show efficacy. It seems clear now that the existing data obtained in preclinical research have depicted an incomplete picture of stroke pathophysiology. In order to ameliorate bench-to-bed translation, in this review we first describe the main actors on stroke inflamma...
Source: Brain, Behavior, and Immunity - October 1, 2020 Category: Neurology Authors: Levard D, Buendia I, Lanquetin A, Glavan M, Vivien D, Rubio M Tags: Brain Behav Immun Source Type: research

Association of obesity with recurrent stroke and cardiovascular events.
CONCLUSIONS: Our results showed that obesity is a significant risk factor for recurrent stroke, although obesity was not associated significantly with myocardial infarction and death after 5-years of first stroke. Further clinical goal-directed weight reduction outcome trials in this area will be critical to validate the most effective approaches and, ultimately, to guide policy is certainly needed. PMID: 33041060 [PubMed - as supplied by publisher]
Source: Revue Neurologique - October 14, 2020 Category: Neurology Tags: Rev Neurol (Paris) Source Type: research

Prevalence and Risk Factors of High-Risk Population for Stroke: A Population-Based Cross-Sectional Survey in Southwestern China
With the aging of the population and the change of lifestyle in China, the prevalence and risk factors of the high-risk population for stroke may change. However, few studies performed community-based high-risk stroke population surveys in China. Hence, we performed this multicenter, cross-sectional, and community-based survey in Sichuan of southwestern China, according to the China National Stroke Screening Survey (CNSSS) program in 2015. The residents aged ≥ 40 years volunteered to participate in the face-to-face survey in 8 communities in Sichuan. The 8 communities were selected using the cluster randomization method....
Source: Frontiers in Neurology - March 2, 2022 Category: Neurology Source Type: research

Prevalence of stroke and associated risk factors: a population-based cross-sectional study from the Qinghai-Tibet Plateau of China
Conclusions The prevalence of stroke, the related risk factors and the detection rate of high-risk individuals were clarified. The prevalence rates of hypertension, overweight or obesity and diabetes in the Qinghai-Tibet Plateau were all higher than the Chinese average. Higher-altitude exposure may be an independent risk factor for stroke.
Source: BMJ Open - November 22, 2022 Category: General Medicine Authors: Li, Z., Hu, Q., Ji, W., Fan, Q. Tags: Open access, Epidemiology Source Type: research

Sex differences and risk factors in recurrent ischemic stroke
ConclusionHypertension and dyslipidemia were significant risk factors of recurrent ischemic stroke in both genders. Smoking and alcohol drinking were significant risk factors associated with ischemic stroke recurrence in males. Therefore, smoking cessation and alcohol abstinence are recommended after the first stroke to prevent recurrent ischemic stroke especially for males. Diabetes was a significant risk factor of ischemic stroke recurrence in females. More extensive studies are needed to understand the causal relationship of each factors with ischemic stroke recurrence according to sex differences and specification of p...
Source: Frontiers in Neurology - January 26, 2023 Category: Neurology Source Type: research