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Total 234 results found since Jan 2013.

Risks of Epilepsy During Pregnancy
Epilepsy is a common disease that affects 1 in 26 individuals in their lifetime. According to a National Institute of Neurological Disorders and Stroke assessment, with 2 million affected individuals, epilepsy ranks only fourth to migraine, stroke, and Alzheimer disease in the prevalence of neurological disorders. Epilepsy affects more people than autism, amyotrophic lateral sclerosis, cerebral palsy, multiple sclerosis, and Parkinson disease combined. Approximately 0.3% to 0.5% of all pregnancies are among women with epilepsy (WWE). The risks during pregnancy in WWE have been uncertain.
Source: JAMA Neurology - July 6, 2015 Category: Neurology Source Type: research

Probiotic supplementation in children with autism spectrum disorder
Scenario A mother of a 4 year old with autism spectrum disorder (ASD) attends the paediatric outpatient clinic. Her son has significant behavioural difficulties, tantrums that are difficult to control, an obsession with spinning wheels and sensory difficulties. She has heard and read about the advantages of probiotic supplementation (PS) in ASD. She wants to know if her son should be given probiotics to improve his behaviour. You wonder if there is any evidence that regular PS improve behaviour in children with ASD. Structured clinical question: In children with proven ASD (patient), does supplementation with any probiotic...
Source: Archives of Disease in Childhood - April 17, 2015 Category: Pediatrics Authors: Srinivasjois, R., Rao, S., Patole, S. Tags: ADC Archimedes, Clinical genetics, Stroke, Childhood nutrition, Child and adolescent psychiatry (paedatrics), Childhood nutrition (paediatrics), Child health, Autism, Asperger syndrome, Pervasive developmental disorder, Personality disorders Source Type: research

HyDRA: gene prioritization via hybrid distance-score rank aggregation
Summary: Gene prioritization refers to a family of computational techniques for inferring disease genes through a set of training genes and carefully chosen similarity criteria. Test genes are scored based on their average similarity to the training set, and the rankings of genes under various similarity criteria are aggregated via statistical methods. The contributions of our work are threefold: (i) first, based on the realization that there is no unique way to define an optimal aggregate for rankings, we investigate the predictive quality of a number of new aggregation methods and known fusion techniques from machine lea...
Source: Bioinformatics - April 2, 2015 Category: Bioinformatics Authors: Kim, M., Farnoud, F., Milenkovic, O. Tags: SYSTEMS BIOLOGY Source Type: research

Precision medicine is coming, but not anytime soon
President Obama’s announcement of a Precision Medicine Initiative was one of the few items in this year’s State of the Union address to garner bipartisan support. And for good reason. Precision medicine, also known as personalized medicine, offers the promise of health care — from prevention to diagnosis to treatment — based on your unique DNA profile. Who wouldn’t want that? We’ve already had a taste of precision medicine. Relatively low-tech therapies like eyeglasses, orthotic devices, allergy treatments, and blood transfusions have long been personalized for the individual. Genetic analysis o...
Source: New Harvard Health Information - March 26, 2015 Category: Consumer Health News Authors: Beverly Merz Tags: Health care personalized health care precision medicine Source Type: news

11 Reasons Your Crazy Cat Obsession Makes You Happier And Healthier
Feline fans, rejoice: Your cat isn't just a cute and cuddly ball of fluff -- he's also incredibly good for your health. Even pet owners who prefer puppies can't deny the major benefits that come along with caring for a furry friend of either species. Science shows that pets can help prevent allergies in kids, ward off respiratory infections, improve your mood and even boost self-esteem. Whether you're a crazy cat lady or a dude ready to publicly proclaim your obsession with your feline friend, get ready to celebrate the many pros of being a proud cat owner -- all negative stereotypes aside. Here are 11 reasons we should...
Source: Healthy Living - The Huffington Post - March 15, 2015 Category: Consumer Health News Source Type: news

Microglia and neuroprotection
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Source: Journal of Neurochemistry - February 18, 2015 Category: Neuroscience Authors: Zhihong Chen, Bruce D. Trapp Tags: Review Source Type: research

Oxytocin shows promise for improving social skills in autistic mice
UCLA Dr. Daniel Geschwind People with autism spectrum disorders have difficulty with social behavior and communication, which can make it challenging to form friendships, engage in routine conversations or pick up on the social cues that are second nature to most people. Similarly, mice with symptoms of autism show little interest in interacting or socializing with other mice. A drug called risperidone has been shown to treat some symptoms of autism — including repetitive behaviors — in both humans and mice, but so far no medication has been found to help improve the ability to socialize. In a study published online b...
Source: UCLA Newsroom: Health Sciences - January 27, 2015 Category: Universities & Medical Training Source Type: news

Retour aux sources: defining the structural basis of glutamate receptor activation.
Abstract Ionotropic glutamate receptors (iGluRs) are the major excitatory neurotransmitter receptor in the vertebrate CNS and, as a result, their activation properties lie at the heart of much of the neuronal network activity observed in the developing and adult brain. iGluRs have also been implicated in many nervous system disorders associated with postnatal development (e.g. autism, schizophrenia), cerebral insult (e.g. stroke, epilepsy), and disorders of the ageing brain (e.g. Alzheimer's disease, Parkinsonism). In view of this, an emphasis has been placed on understanding how iGluRs activate and desensitize in...
Source: The Journal of Physiology - January 1, 2015 Category: Physiology Authors: Dawe GB, Aurousseau MR, Daniels BA, Bowie D Tags: J Physiol Source Type: research

NIH Funds Robots to Assist People with Disabilities
New research in robotics might help with stroke rehabilitation, guide wheelchairs, and assist children with Autism
Source: Disabled World - December 11, 2014 Category: Disability Tags: Assistive Technology Source Type: news

NIH Funds Robots To Assist People With Disabilities
New research in robotics might help with stroke rehabilitation, guide wheelchairs, and assist children with Autism Spectrum Disorder. Projects investigating co-robotics are the focus of new funding from the National Institutes of Health.
Source: Medical Design Online News - December 9, 2014 Category: Medical Equipment Source Type: news

Neurofeedback: How Is It Used for Treatment?
How does neurofeedback treat symptoms such as anxiety, sleeping problems, headaches, memory problems and ADHD? Read how Neurofeedback treats these symptoms, along with causes relating to dysregulation of the brainwaves and/or neural hubs as seen in a concussion, stroke, MS, autism, and parkinson disease. Neurofeedback can also be used to improve brain function!read more
Source: Psychology Today Anxiety Center - November 17, 2014 Category: Psychiatry & Psychology Authors: Diane Roberts Stoler, Ed.D. Tags: Anxiety Autism Cognition Depression Health Integrative Medicine Memory Neuroscience Sleep Stress Therapy brain fitness brain waves concussion neurofeedback qeeg stroke Source Type: news

Safety of Noninvasive Brain Stimulation in Children and Adolescents
Conclusion Our findings indicate that both repetitive TMS and tCS are safe modalities in children and adolescents with various neurological conditions, especially when safety guidelines are followed. The incidence of adverse events appears to be similar to that observed in adults; however, further studies with longer treatment and follow-up periods are needed to better understand the benefits and tolerance of long-term use of NIBS in children.
Source: Brain Stimulation - November 4, 2014 Category: Neurology Source Type: research

Erythropoietin attenuates loss of potassium chloride co-transporters following prenatal brain injury
Publication date: July 2014 Source:Molecular and Cellular Neuroscience, Volume 61 Author(s): L.L. Jantzie , P.M. Getsy , D.J. Firl , C.G. Wilson , R.H. Miller , S. Robinson Therapeutic agents that restore the inhibitory actions of γ-amino butyric acid (GABA) by modulating intracellular chloride concentrations will provide novel avenues to treat stroke, chronic pain, epilepsy, autism, and neurodegenerative and cognitive disorders. During development, upregulation of the potassium-chloride co-transporter KCC2, and the resultant switch from excitatory to inhibitory responses to GABA guide the formation of essential inhibit...
Source: Molecular and Cellular Neuroscience - November 3, 2014 Category: Neuroscience Source Type: research

Safety of Noninvasive Brain Stimulation in Children and Adolescents
Noninvasive brain stimulation (NIBS) techniques such as transcranial magnetic stimulation (TMS) and transcranial current stimulation (tCS) have the potential to mitigate a variety of symptoms associated with neurological and psychiatric conditions, including stroke, cerebral palsy, autism, depression, and Tourette syndrome. While the safety of these modalities has been established in adults, there is a paucity of research assessing the safety of NIBS among children.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - October 27, 2014 Category: Neurology Authors: Chandramouli Krishnan, Luciana Santos, Mark D. Peterson, Margaret Ehinger Source Type: research

Asperger Syndrome
information prepared by the National Institute of Neurological Disorders and Stroke (NINDS).
Source: NINDS Disorders: National Institute of Neurological Disorders and Stroke - October 26, 2014 Category: Neurology Source Type: research