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Total 234 results found since Jan 2013.

Prevalence of people who could benefit from augmentative and alternative communication (AAC) in the UK: determining the need.
CONCLUSIONS & IMPLICATIONS: To provide accurate figures on the potential need for and use of AAC, data need to be consistently and accurately recorded and regularly reviewed at a community level. The existing data suggest an urgent need for more accurate and up to date information to be captured about the need for AAC in the UK to provide better services and ensure access to AAC strategies, equipment and support. PMID: 27113569 [PubMed - as supplied by publisher]
Source: International Journal of Language and Communication Disorders - April 25, 2016 Category: Speech Therapy Authors: Creer S, Enderby P, Judge S, John A Tags: Int J Lang Commun Disord Source Type: research

Unspoken Words: Art Helps Young Girl With Autism Communicate
BOSTON (CBS) – This Autism Awareness Month, a new exhibit called “Unspoken Words” is open at the 42 Maple Gallery in Bethlehem, NH. It shows the powerful expression of 10 artists who are on the autism spectrum. And wait until you meet one of those artists. For Lucy Sutton of Braintree, the focus is on communication, beauty and even therapy. Lucy just turned 4, and paints like nothing you’ve ever seen. With her canvas on top of a sheet spread on the family room floor and her paints carefully chosen, she picks her brushes and goes to town. Lucy is on the autism spectrum, with all the challenges that ...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - April 6, 2016 Category: Consumer Health News Authors: deanreddington Tags: Health Local News Seen On WBZ-TV Syndicated Local Watch Listen Autism Paula Ebben Source Type: news

Disparity of Epileptiform Discharges Among Children with Autism with and without Epilepsy (P3.249)
CONCLUSIONS: As expected, children with ASD frequently exhibit abnormal EEGs and at least rare to occasional focal, multifocal, or generalized ED. However, the presence of epilepsy does not explain the substantial observed burden of frequent ED seen in children with autism. Further study is warranted to determine if the burden (frequency and distribution) of ED is associated with severity of autism, and whether treatment of epileptiform discharges alleviates core autistic symptoms.Disclosure: Dr. Lee has nothing to disclose. Dr. Hayward has nothing to disclose. Dr. Hung has nothing to disclose. Dr. Cao has nothing to discl...
Source: Neurology - April 3, 2016 Category: Neurology Authors: Lee, V., Hayward, O., Hung, P., Cao, T., Hutman, T., Hussain, S., Sharifi-Hannauer, P. Tags: Child Neurology and Developmental Neurology: Epilepsy, Hypoxia, and Stroke Source Type: research

MMP‐9 in translation: from molecule to brain physiology, pathology, and therapy
This article is part of the 60th Anniversary special issue. MMP‐9, through cleavage of specific target proteins, plays a major role in synaptic plasticity and neuroinflammation, and by those virtues contributes to brain physiology and a host of neurological and psychiatric disorders. This article is part of the 60th Anniversary special issue.
Source: Journal of Neurochemistry - March 21, 2016 Category: Neuroscience Authors: Behnam Vafadari, Ahmad Salamian, Leszek Kaczmarek Tags: Bench to Bedside Source Type: research

MMP ‐9 in translation: from molecule to brain physiology, pathology, and therapy
This article is part of the 60th Anniversary special issue. MMP‐9, through cleavage of specific target proteins, plays a major role in synaptic plasticity and neuroinflammation, and by those virtues contributes to brain physiology and a host of neurological and psychiatric disorders. This article is part of the 60th Anniversary special issue.
Source: Journal of Neurochemistry - March 20, 2016 Category: Neuroscience Authors: Behnam Vafadari, Ahmad Salamian, Leszek Kaczmarek Tags: Bench to Bedside Source Type: research

Zimbabwe Needs SLPs in Public Hospitals
Zimbabwe desperately needs speech-language pathologists, according to the Africa Health Network in an article on Voice of America. State-owned hospitals and other public health organizations—especially those in the capital city of Harare—can’t keep SLPs employed. Government officials say this occurred primarily because of low salaries. “Right now there is not a single speech therapist working in public service in Zimbabwe,” says Michele Angeletti, country representative of Christian Blind Mission. This was confirmed by the permanent secretary in the Ministry of Health and Child Care, Dr. Gerald Gwinji, who says t...
Source: American Speech-Language-Hearing Association (ASHA) Press Releases - March 9, 2016 Category: Speech Therapy Authors: Shelley D. Hutchins Tags: News Autism Spectrum Disorder Speech Disorders speech-language pathology Swallowing Disorders Traumatic Brain Injury Source Type: blogs

Environmental Pollution: An Under-recognized Threat to Children’s Health, Especially in Low- and Middle-Income Countries
Conclusions Patterns of disease are changing rapidly in LMICs. Pollution-related chronic diseases are becoming more common. This shift presents a particular problem for children, who are proportionately more heavily exposed than are adults to environmental pollutants and for whom these exposures are especially dangerous. Better quantification of environmental exposures and stepped-up efforts to understand how to prevent exposures that cause disease are needed in LMICs and around the globe. To confront the global problem of disease caused by pollution, improved programs of public health monitoring and environmental protecti...
Source: EHP Research - March 1, 2016 Category: Environmental Health Authors: Web Admin Tags: Brief Communication March 2016 Source Type: research

A Quantitative Summary of The Listening Program (TLP) Efficacy Studies: What Areas Were Found to Improve by TLP Intervention?
Abstract A quantitative summary of existing research examining the effects of The Listening Program (TLP) on various functions in children is presented. Nine studies were used, looking at TLP intervention effects across studies, within each study and for various outcome measures. The studies looked at TLP intervention on children with autism spectrum disorder, Down syndrome, learning disabilities, auditory processing disorders, attention deficit hyperactivity disorders, Rhett syndrome, dyspraxia, cerebral palsy, fibromyalgia, arthritis and stroke. The magnitude of the TLP effect size revealed a mean value of 0.41 across al...
Source: Occupational Therapy International - February 17, 2016 Category: Occupational Health Authors: Sadako Vargas, Jay R. Lucker Tags: Research Article Source Type: research

Dextromethorphan: An update on its utility for neurological and neuropsychiatric disorders
Publication date: Available online 28 January 2016 Source:Pharmacology & Therapeutics Author(s): Linda Nguyen, Kelan L. Thomas, Brandon P. Lucke-Wold, John Z. Cavendish, Molly S. Crowe, Rae R. Matsumoto Dextromethorphan (DM) is a commonly used antitussive and is currently the only FDA-approved pharmaceutical treatment for pseudobulbar affect. Its safety profile and diverse pharmacologic actions in the central nervous system have stimulated new interest for repurposing it. Numerous preclinical investigations and many open-label or blinded clinical studies have demonstrated its beneficial effects across a var...
Source: Pharmacology and Therapeutics - January 28, 2016 Category: Drugs & Pharmacology Source Type: research

NIH genome sequencing program targets the genomic bases of common, rare disease
The National Institutes of Health will fund a set of genome sequencing and analysis centers whose research will focus on understanding the genomic bases of common and rare human diseases. The National Human Genome Research Institute (NHGRI), part of NIH, today launched the Centers for Common Disease Genomics (CCDG), which will use genome sequencing to explore the genomic contributions to common diseases such as heart disease, diabetes, stroke and autism. NHGRI also announced the next phase of a complementary program, the Centers for Mendelian Genomics (CMG), which will continue investigating the genomic underpinnings of ra...
Source: NHGRI Press Releases - January 14, 2016 Category: Genetics & Stem Cells Source Type: news

$60 million to fund study of genetics underlying common diseases
(Washington University School of Medicine) The McDonnell Genome Institute at Washington University School of Medicine in St. Louis will receive $60 million from the National Institutes of Health to study the genetics of common diseases, such as heart disease, diabetes, stroke, autism and epilepsy.
Source: EurekAlert! - Medicine and Health - January 14, 2016 Category: Global & Universal Source Type: news

NIH genome sequencing program targets the genomic bases of common, rare disease
(NIH/National Human Genome Research Institute) The National Human Genome Research Institute and other institutes will fund genome sequencing centers to focus on understanding the genomic bases of common and rare human diseases. The Centers for Common Disease Genomics will use genome sequencing to explore the genomics of common diseases such as heart disease, diabetes, stroke and autism. NHGRI is also funding the next phase of the Centers for Mendelian Genomics, which will investigate the genomic underpinnings of rare, inherited diseases.
Source: EurekAlert! - Medicine and Health - January 14, 2016 Category: Global & Universal Source Type: news

Four new recommendations for adolescent health
The yearly “check-up” is the perfect (perhaps only) time to not only see how kids are growing and give any needed shots, but to see how they are doing more generally — and help be sure that they grow into healthy, happy adults. After all, prevention is really what pediatrics is all about. That’s why the American Academy of Pediatrics (AAP) has a checklist for pediatricians called “Recommendations for Preventive Pediatric Health Care.” These recommendations, which are updated every few years, are based on the most up-to-date research about the health of children now — and in the future. While the latest versio...
Source: New Harvard Health Information - January 4, 2016 Category: Consumer Health News Authors: Claire McCarthy, MD Tags: Children's Health Parenting Prevention Source Type: news

Statistical methods for studying disease subtype heterogeneity
A fundamental goal of epidemiologic research is to investigate the relationship between exposures and disease risk. Cases of the disease are often considered a single outcome and assumed to share a common etiology. However, evidence indicates that many human diseases arise and evolve through a range of heterogeneous molecular pathologic processes, influenced by diverse exposures. Pathogenic heterogeneity has been considered in various neoplasms such as colorectal, lung, prostate, and breast cancers, leukemia and lymphoma, and non‐neoplastic diseases, including obesity, type II diabetes, glaucoma, stroke, cardiovascular d...
Source: Statistics in Medicine - December 1, 2015 Category: Statistics Authors: Molin Wang, Donna Spiegelman, Aya Kuchiba, Paul Lochhead, Sehee Kim, Andrew T. Chan, Elizabeth M. Poole, Rulla Tamimi, Shelley S. Tworoger, Edward Giovannucci, Bernard Rosner, Shuji Ogino Tags: Tutorial in Biostatistics Source Type: research

Research Roundup
DHA study finds no effect on PTSD symptoms after injury Extended‐release guanfacine effective for youths with autism Retrospective study of varenicline finds no evidence of adverse risk Adjunctive quetiapine may improve outcomes in PMDD treatment Tricyclic antidepressants associated with recurrence of stroke Cognition not altered in postmenopausal women on hormones
Source: The Brown University Psychopharmacology Update - November 20, 2015 Category: Psychiatry Tags: Research Roundup Source Type: research