Filtered By:
Procedure: Transplants
This page shows you your search results in order of date. This is page number 13.
Order by Relevance | Date
Total 526 results found since Jan 2013.
Clinical and biological impact of SAMHD1 expression in mantle cell lymphoma
AbstractSAMHD1 is a deoxynucleoside triphosphate triphosphohydrolase (dNTPase) that restricts viral replication in infected cells and limits the sensitivity to cytarabine by hydrolysing its active metabolite, as recently shown in acute myeloid leukemia. Cytarabine is an essential component in the Nordic mantle cell lymphoma protocols (MCL2 and MCL3) for induction and high-dose chemotherapy treatment before autologous stem cell transplantation for younger patients with mantle cell lymphoma (MCL). We here investigated the expression of SAMHD1 in a population-based cohort of MCL (N = 150). SAMHD1 was highly variably expre...
Source: Virchows Archiv - November 4, 2021 Category: Pathology Source Type: research
MsrB1 Promotes Proliferation and Invasion of Colorectal Cancer Cells via GSK-3 β/β-catenin Signaling Axis
In conclusion, the oncogenic role and related mechanisms of MsrB1 in CRC discovered in our work determined the potential role of MsrB1 as a biomarker and may provide a new target for clinical therapy of CRC.PMID:34719306 | PMC:PMC8558597 | DOI:10.1177/09636897211053203
Source: Cell Transplantation - November 1, 2021 Category: Cytology Authors: Xiao-Yu Chen Sheng-Yong Yang Xiao-Jie Ruan Hong-Yue Ding Ning-Xi Wang Fang Liu Jia-Chu Li Yi Li Source Type: research
Dysfunctional lactate metabolism in human alveolar type II cells from idiopathic pulmonary fibrosis lung explant tissue
CONCLUSIONS: These results are consistent with the concept that altered lactate metabolism may be an underlying feature of AEC2 dysfunction in IPF and may be a novel and important target for therapeutic treatment.PMID:34711218 | DOI:10.1186/s12931-021-01866-x
Source: Cell Research - October 29, 2021 Category: Cytology Authors: Danforth A Newton Robyn G Lottes Rita M Ryan Demetri D Spyropoulos John E Baatz Source Type: research
lncRNA OR3A4 Promotes the Proliferation and Metastasis of Ovarian Cancer Through KLF6 Pathway
Conclusion: lncRNA OR3A4 promotes the proliferation and metastasis of ovarian cancer through the KLF6 pathway.
Source: Frontiers in Pharmacology - October 27, 2021 Category: Drugs & Pharmacology Source Type: research
Growth Arrest Specific-6 and Axl Coordinate Inflammation and Hypertension
Conclusions: We define a previously unrecognized interaction of human endothelial cells and monocytes that promote formation of AS DCs in hypertension and show a critical role of GAS6 and Axl signaling in both immune cells and endothelial cells. This pathway is potentially a novel therapeutic target to reduce inflammation and end organ damage in hypertension.PMID:34565181 | DOI:10.1161/CIRCRESAHA.121.319643
Source: Circulation Research - September 27, 2021 Category: Cardiology Authors: Justin Pieter Van Beusecum Natalia Ruggeri Barbaro Charles Duncan Smart David M Patrick Roxana Loperena Shilin Zhao Nestor de la Visitacion Mingfang Ao Liang Xiao Cyndya A Shibao David G Harrison Source Type: research
Roles of VE-Cadherin in Hypoxia Induced Injury of Pulmonary Microvascular Endothelial Barrier
CONCLUSIONS: These data verify that VE-cadherin expression played an important role in hypoxia induced PMVECs apoptosis and cellular skeletal recombination.PMID:34473045 | DOI:10.1532/hsf.3405
Source: The Heart Surgery Forum - September 2, 2021 Category: Cardiovascular & Thoracic Surgery Authors: Lizhe Zhong Xiurong Gao Yongli Chen Zhaoxiang Yu Shuo Jin Chunlei Zhu Source Type: research
