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Total 526 results found since Jan 2013.

Roles of VE-Cadherin in Hypoxia Induced Injury of Pulmonary Microvascular Endothelial Barrier
CONCLUSIONS: These data verify that VE-cadherin expression played an important role in hypoxia induced PMVECs apoptosis and cellular skeletal recombination.PMID:34473045 | DOI:10.1532/hsf.3405
Source: The Heart Surgery Forum - September 2, 2021 Category: Cardiovascular & Thoracic Surgery Authors: Lizhe Zhong Xiurong Gao Yongli Chen Zhaoxiang Yu Shuo Jin Chunlei Zhu Source Type: research

Oct4-dependent FoxC1 activation improves the survival and neovascularization of mesenchymal stem cells under myocardial ischemia
CONCLUSIONS: Together, these studies demonstrate that the FoxC1/Oct4 axis is an essential aspect for survival and neovascularization of MSCs in the ischemic conditions and represents a potential therapeutic target for enhancing cardiac repair.PMID:34454602 | DOI:10.1186/s13287-021-02553-w
Source: Cell Research - August 29, 2021 Category: Cytology Authors: Zhou Ji Songsheng Chen Jin Cui Weiguang Huang Rui Zhang Jianrui Wei Shaoheng Zhang Source Type: research

Interleukin-18: A Novel Participant in the Occurrence, Development, and Drug Therapy of Obliterative Bronchiolitis Postlung Transplantation
CONCLUSIONS: IL-18 could be a novel molecular involved in the occurrence, development, and drug treatment of OB.PMID:34367377 | PMC:PMC8337162 | DOI:10.1155/2021/5586312
Source: Disease Markers - August 9, 2021 Category: Laboratory Medicine Authors: Ping Shu Wei Zhang Yanfei Zhang Yanfeng Zhao Yuping Li Xiaoqing Zhang Source Type: research

Viruses, Vol. 13, Pages 1353: Chk1 and the Host Cell DNA Damage Response as a Potential Antiviral Target in BK Polyomavirus Infection
omas D. Friedrich The human BK polyomavirus (BKPyV) is latent in the kidneys of most adults, but can be reactivated in immunosuppressed states, such as following renal transplantation. If left unchecked, BK polyomavirus nephropathy (PyVAN) and possible graft loss may result from viral destruction of tubular epithelial cells and interstitial fibrosis. When coupled with regular post-transplant screening, immunosuppression reduction has been effective in limiting BKPyV viremia and the development of PyVAN. Antiviral drugs that are safe and effective in combating BKPyV have not been identified but would be a benefit in com...
Source: Viruses - July 13, 2021 Category: Virology Authors: Lydia E. Hainley Martina S. Hughson Amithi Narendran Ralph Smith Justin Arthur Alida Hayner-Buchan David J. Conti John M. Lehman Thomas D. Friedrich Tags: Article Source Type: research