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Procedure: Transplants
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Total 526 results found since Jan 2013.
Prof. Transient receptor potential vanilloid 4 promotes the growth of non-small cell lung cancer by regulating Foxp3
CONCLUSIONS: Antitumor effects caused by TRPV4 inhibition in NSCLC might be attributed to the suppression of Foxp3 which induced subsequent cell apoptosis. Thus, pharmacological inhibition of TRPV4 may be a promising option for NSCLC treatment.PMID:34995050 | DOI:10.18388/abp.2020_5614
Source: Acta Biochim Pol - January 7, 2022 Category: Biochemistry Authors: Jiang-Tao Pu Tao Zhang Kai-Ming He Deng-Guo Zhang Zhang-Yu Teng Yun-Fei Wu Source Type: research
Sevoflurane preconditioning promotes mesenchymal stem cells to relieve myocardial ischemia/reperfusion injury via TRPC6-induced angiogenesis
CONCLUSION: The current findings reveal that sevoflurane preconditioned MSCs boost angiogenesis in HUVECs subjected to H/R insult and attenuate myocardial I/R injury, which may be mediated by TRPC6 up-regulated HIF-1α, CXCR4 and VEGF.PMID:34809715 | DOI:10.1186/s13287-021-02649-3
Source: Cell Research - November 23, 2021 Category: Cytology Authors: Jinting Yang Lihui Tang Fengjiang Zhang Tingting Yang Ting Lu Kai Sun Na Sun Jinxuan Ren Min Yan Source Type: research
Nanog/NFATc1/Osterix signaling pathway-mediated promotion of bone formation at the tendon-bone interface after ACL reconstruction with De-BMSCs transplantation
CONCLUSIONS: De-BMSCs transplantation could promote bone formation at the tendon-bone interface after ACLR and improve the biomechanical strength of the reconstruction. The Nanog/NFATc1/Osterix signaling pathway mediated the enhanced osteogenic differentiation efficiency of De-BMSCs.PMID:34775995 | DOI:10.1186/s13287-021-02643-9
Source: Cell Research - November 15, 2021 Category: Cytology Authors: Kai Tie Jinghang Cai Jun Qin Hao Xiao Yangfan Shangguan Hui Wang Liaobin Chen Source Type: research
Bortezomib alleviates antibody-mediated rejection in kidney transplantation by facilitating Atg5 expression
J Cell Mol Med. 2021 Nov 3. doi: 10.1111/jcmm.16998. Online ahead of print.ABSTRACTAntibody-mediated rejection (AMR) is one of the most dominant mechanisms responsible for the loss of kidney grafts. Previous researches have shown that donor-specific antibodies (DSAs) are the major mediators of AMR. In order to prolong the survival time of grafts, it is vital to reduce the incidence of AMR and inhibit the generation of DSAs. We established an animal model of AMR by performing kidney transplantation in pre-sensitized rats. Then, we investigated the effect of bortezomib (BTZ) on AMR. We found that BTZ could reduce the serum l...
Source: J Cell Mol Med - November 4, 2021 Category: Molecular Biology Authors: Hong Cheng Bin Xu Lijie Zhang Yi Wang Ming Chen Shuqiu Chen Source Type: research
