Oct4-dependent FoxC1 activation improves the survival and neovascularization of mesenchymal stem cells under myocardial ischemia

CONCLUSIONS: Together, these studies demonstrate that the FoxC1/Oct4 axis is an essential aspect for survival and neovascularization of MSCs in the ischemic conditions and represents a potential therapeutic target for enhancing cardiac repair.PMID:34454602 | DOI:10.1186/s13287-021-02553-w

Source: Cell Research - August 29, 2021 Category: Cytology Authors: Zhou Ji Songsheng Chen Jin Cui Weiguang Huang Rui Zhang Jianrui Wei Shaoheng Zhang Source Type: research