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Cancer: Glioma
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Total 625 results found since Jan 2013.
Interference of P2X4 receptor expression in tumor-associated macrophages suppresses migration and invasion of glioma cells
CONCLUSION: Interference of P2X4 receptor in the TAMs suppresses the migration and invasion of glioma cells possibly by lowering the expressions of IL-1β and IL-18.PMID:35673908 | PMC:PMC9178632 | DOI:10.12122/j.issn.1673-4254.2022.05.05
Source: Journal of Southern Medical University - June 8, 2022 Category: Universities & Medical Training Authors: X Yang H Shen Q Li Z Dai R Yang G Huang R Chen F Wang J Song H Hua Source Type: research
Upregulation of atypical cadherin FAT1 promotes an immunosuppressive tumor microenvironment via TGF- β
Atypical cadherin FAT1 promotes glioblastoma (GBM) by promoting pro-tumorigenic
inflammatory cytokine expression in tumor cells. However, tumors also have an
immunosuppressive microenvironment, maintained by mediators like TGF-β cytokines. Here, we
have studied the role of FAT1 in tumor immune suppression. Our preliminary TIMER2.0
analysis of TCGA database revealed inverse correlation of FAT1 expression with infiltration of
tumor-inhibiting immune cells (like monocytes, T-cells, etc.) and positive correlation with
tumor-promoting immune cells (like myeloid-derived suppressor cells/MDSCs) in various
cancers. ...
Source: Frontiers in Immunology - June 3, 2022 Category: Allergy & Immunology Source Type: research
Hemin protects against Zika virus infection by disrupting virus-endosome fusion
This study elaborated that hemin could play anti-ZIKV activity by disrupting the virus-endosome fusion process and shed new light on developing novel agents against ZIKV infection.PMID:35643150 | DOI:10.1016/j.antiviral.2022.105347
Source: Antiviral Research - June 1, 2022 Category: Virology Authors: Meng-Meng Xu Bing Wu Guan-Gen Huang Chun-Lan Feng Xiao-Han Wang Hao-Yu Wang Yan-Wei Wu Wei Tang Source Type: research
