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Cancer: Glioma
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Total 625 results found since Jan 2013.
CDK-associated Cullin 1 promotes Cell Proliferation and inhibits Cell Apoptosis in Human Glioblastoma
CONCLUSION: CACUL1 can promote cell proliferation and suppress apoptosis of glioma cells and might serve as a potential oncogene for gliomas.PMID:34080964 | DOI:10.2174/1568009621666210602164225
Source: Current Cancer Drug Targets - June 3, 2021 Category: Cancer & Oncology Authors: Xiaohua Zhang Tianying Zhang Xiaojuan Han Zhongying Qiu Jianghong Cheng Xingchun Gao Xingchun Gou Source Type: research
Hypoxia-induced phenotypic transition from highly invasive to less invasive tumors in glioma stem-like cells: Significance of CD44 and osteopontin as therapeutic targets in glioblastoma
Transl Oncol. 2021 May 27;14(8):101137. doi: 10.1016/j.tranon.2021.101137. Online ahead of print.ABSTRACTThe poor prognosis of glioblastoma multiforme (GBM) is primarily due to highly invasive glioma stem-like cells (GSCs) in tumors. Upon GBM recurrence, GSCs with highly invasive and highly migratory activities must assume a less-motile state and proliferate to regenerate tumor mass. Elucidating the molecular mechanism underlying this transition from a highly invasive phenotype to a less-invasive, proliferative tumor could facilitate the identification of effective molecular targets for treating GBM. Here, we demonstrate t...
Source: Translational Oncology - May 30, 2021 Category: Cancer & Oncology Authors: Masahiro Nishikawa Akihiro Inoue Takanori Ohnishi Hajime Yano Saya Ozaki Yonehiro Kanemura Satoshi Suehiro Yoshihiro Ohtsuka Shohei Kohno Shiro Ohue Seiji Shigekawa Hideaki Watanabe Riko Kitazawa Junya Tanaka Takeharu Kunieda Source Type: research
ERK-CREB pathway is involved in HSPB8-mediated glioma cell growth and metastatic properties
CONCLUSION: Silencing HSPB8 can inhibit the malignant features, while facilitate the apoptosis of glioma cells, with inactivation of ERK-CREB pathway.PMID:34043982 | DOI:10.1016/j.yexmp.2021.104653
Source: Experimental and Molecular Pathology - May 27, 2021 Category: Pathology Authors: Xia Li Cui Sun Jing Chen Ji-Fen Ma Yi-Heng Pan Source Type: research
LINC00511 knockdown suppresses glioma cell malignant progression through miR-15a-5p/AEBP1 axis
CONCLUSION: LINC00511 knockdown inhibits glioma cell progression via miR-15a-5p/AEBP1 axis.PMID:33992709 | DOI:10.1016/j.brainresbull.2021.05.010
Source: Brain Research - May 16, 2021 Category: Neurology Authors: Zhen Liu Bei Tao Linkun Li Pin Liu Kaiguo Xia Chuanhong Zhong Source Type: research
