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Cancer: Glioma
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Total 625 results found since Jan 2013.
Retracted IQGAP1 ‑siRNA inhibits proliferation and metastasis of U251 and U373 glioma cell lines
Mol Med Rep. 2023 Nov;28(5):207. doi: 10.3892/mmr.2023.13094. Epub 2023 Sep 21.ABSTRACTFollowing the publication of this paper, it was drawn to the Editor's attention by a concerned reader that the GAPDH control western blotting data shown in Fig. 1C, and other western blotting data included in Figs. 2D and 7C and D, were strikingly similar to data appearing in different form in other articles written by different authors at different research institutes. Owing to the fact that the contentious data in the above article were already under consideration for publication, or had already been published elsewhere, prior to its s...
Source: Molecular Medicine Reports - September 21, 2023 Category: Molecular Biology Authors: Bo Diao Ying Liu Yi Zhang Jing Yu Jun Xie Guo-Zheng Xu Source Type: research
Autocrine motility factor receptor promotes the malignancy of glioblastoma by regulating cell migration and invasion
CONCLUSION: This study suggests that AMFR could be used as a therapeutic strategy for the clinical treatment of glioblastoma.PMID:37703903 | DOI:10.1080/01616412.2023.2257463
Source: Cell Research - September 13, 2023 Category: Cytology Authors: Yao Zhang Xiuping Wang Guanghui Chen Yajing Lu Qiang Chen Source Type: research
Multilevel chitosan-gelatin particles loaded with P4HA1 siRNA suppress glioma development
Drug Deliv Transl Res. 2023 Sep 4. doi: 10.1007/s13346-023-01422-8. Online ahead of print.ABSTRACTIt has been reported that prolyl 4-hydroxylase subunit alpha 1 (P4HA1) promoted tumor growth and metastasis of glioma; thus, targeting P4HA1 may be a promising therapeutic strategy against glioma. In consideration of the instability of siRNA in vivo, the chitosan-gelatin microspheres loaded with P4HA1 siRNA (P4HA1 siRNA@CGM) were employed. Firstly, the gel electrophoresis and hemolytic test were performed to assess the stability and blood compatibility of P4HA1 siRNA@CGM. Then, methyl thiazolyl tetrazolium (MTT), cell colony f...
Source: Cell Research - September 4, 2023 Category: Cytology Authors: Yiting Zhou Jiajia Tian Yi Zhu Yating Zhang Xudong Zhao Source Type: research
Lactate-induced up-regulation of PLEKHA4 promotes proliferation and apoptosis of human glioma cells
CONCLUSION: PLEKHA4 knockdown inhibited the proliferation of glioma cells and promoted apoptosis by inhibiting the activation of the MAPK signaling pathway and expression of β-catenin. Lactic acid produced by glycolysis upregulates the expression of PLEKHA4 in glioma cells.PMID:37488789 | PMC:PMC10366507 | DOI:10.12122/j.issn.1673-4254.2023.07.03
Source: Journal of Southern Medical University - July 25, 2023 Category: Universities & Medical Training Authors: J Ye W Xu B Xi N Wang T Chen Source Type: research
